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DE69800488D1 - Verfahren zur Identifizierung von Verbindungen zur Hemmung von neoplastischen Verletzungen - Google Patents

Verfahren zur Identifizierung von Verbindungen zur Hemmung von neoplastischen Verletzungen

Info

Publication number
DE69800488D1
DE69800488D1 DE69800488T DE69800488T DE69800488D1 DE 69800488 D1 DE69800488 D1 DE 69800488D1 DE 69800488 T DE69800488 T DE 69800488T DE 69800488 T DE69800488 T DE 69800488T DE 69800488 D1 DE69800488 D1 DE 69800488D1
Authority
DE
Germany
Prior art keywords
compound
activity
identifying compounds
cgmp
inhibiting neoplastic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69800488T
Other languages
English (en)
Other versions
DE69800488T2 (de
Inventor
Rifat Pamukcu
Gary A Piazza
W Joseph Thompson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
OSI Pharmaceuticals LLC
Original Assignee
Cell Pathways Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/866,027 external-priority patent/US5858694A/en
Application filed by Cell Pathways Inc filed Critical Cell Pathways Inc
Application granted granted Critical
Publication of DE69800488D1 publication Critical patent/DE69800488D1/de
Publication of DE69800488T2 publication Critical patent/DE69800488T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/44—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving esterase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/533—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving isomerase

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69800488T 1997-05-30 1998-05-29 Verfahren zur Identifizierung von Verbindungen zur Hemmung von neoplastischen Verletzungen Expired - Lifetime DE69800488T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/866,027 US5858694A (en) 1997-05-30 1997-05-30 Method for identifying compounds for inhibition of cancerous lesions
US4673998A 1998-03-24 1998-03-24

Publications (2)

Publication Number Publication Date
DE69800488D1 true DE69800488D1 (de) 2001-02-22
DE69800488T2 DE69800488T2 (de) 2001-08-09

Family

ID=26724247

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69800488T Expired - Lifetime DE69800488T2 (de) 1997-05-30 1998-05-29 Verfahren zur Identifizierung von Verbindungen zur Hemmung von neoplastischen Verletzungen
DE0881300T Pending DE881300T1 (de) 1997-05-30 1998-05-29 Verfahren zur Identifizierung von Verbindungen zur Hemmung von neoplastischen Verletzungen

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE0881300T Pending DE881300T1 (de) 1997-05-30 1998-05-29 Verfahren zur Identifizierung von Verbindungen zur Hemmung von neoplastischen Verletzungen

Country Status (15)

Country Link
US (3) US6500610B1 (de)
EP (2) EP1038523A3 (de)
JP (3) JP3053381B2 (de)
KR (1) KR100304859B1 (de)
AT (1) ATE198771T1 (de)
AU (1) AU709666B2 (de)
CA (1) CA2238283C (de)
CZ (1) CZ295868B6 (de)
DE (2) DE69800488T2 (de)
DK (1) DK0881300T3 (de)
ES (1) ES2132055T3 (de)
IL (1) IL124699A (de)
NO (1) NO321717B1 (de)
TR (1) TR199800960A3 (de)
TW (1) TW591111B (de)

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* Cited by examiner, † Cited by third party
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US20040009464A1 (en) * 1998-10-15 2004-01-15 Li Liu Methods for identifying compounds for inhibition of neoplastic lesions, and pharmacetical compositions containing such compounds
US20050244914A1 (en) * 1999-10-08 2005-11-03 Li Liu Methods for identifying compounds for inhibition of neoplastic lesions, and pharmaceutical compositions containing such compounds
DE10060388A1 (de) * 2000-12-05 2002-06-06 Merck Patent Gmbh Verwendung von Pyrazolo [4,3-d]pyrimidinen
FR2824334B1 (fr) 2001-05-03 2003-10-10 Coletica Procede pour tester une substance eventuellement active dans le domaine de la lipolyse et son utilisation principalement cosmetique
JP2005516586A (ja) * 2001-07-20 2005-06-09 ボード オブ トラスティーズ オブ ザ ユニヴァースティ オブ イリノイ 癌の処置に対する遺伝子標的を同定するための試薬および方法
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JP2007224007A (ja) * 2006-03-27 2007-09-06 Univ De Santiago De Compostela ｙｅｓｓｏｔｏｘｉｎｓのヒト腫瘍細胞増殖抑制剤としての治療的な使用
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CZ165198A3 (cs) 1999-01-13
NO321717B1 (no) 2006-06-26
NO982477D0 (no) 1998-05-29
KR19980087436A (ko) 1998-12-05
EP1038523A2 (de) 2000-09-27
EP1038523A3 (de) 2000-10-25
HK1012196A1 (en) 1999-07-30
IL124699A (en) 2003-02-12
ES2132055T1 (es) 1999-08-16
TR199800960A2 (xx) 1998-12-21
TW591111B (en) 2004-06-11
DE881300T1 (de) 1999-08-19
KR100304859B1 (ko) 2001-11-30
US6500610B1 (en) 2002-12-31
ES2132055T3 (es) 2001-05-01
TR199800960A3 (tr) 1998-12-21
DE69800488T2 (de) 2001-08-09
US20030190686A1 (en) 2003-10-09
JPH1194823A (ja) 1999-04-09
CZ295868B6 (cs) 2005-11-16
ATE198771T1 (de) 2001-02-15
NO982477L (no) 1998-12-01
JP3234818B2 (ja) 2001-12-04
CA2238283C (en) 2002-08-20
AU6979498A (en) 1998-12-10
CA2238283A1 (en) 1998-11-30
EP0881300A3 (de) 1999-01-20
AU709666B2 (en) 1999-09-02
JP3053381B2 (ja) 2000-06-19
US20030004093A1 (en) 2003-01-02
IL124699A0 (en) 1998-12-06
JP2000028601A (ja) 2000-01-28
EP0881300B1 (de) 2001-01-17
DK0881300T3 (da) 2001-06-18
EP0881300A2 (de) 1998-12-02

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