DE69700470D1 - Neue 19-nor-pregnen-derivate - Google Patents

Neue 19-nor-pregnen-derivate

Info

Publication number: DE69700470D1
Authority: DE; Germany
Prior art keywords: pregnen; derivatives; new; pregnen derivatives
Prior art date: 1996-01-22
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

DE69700470T

Other languages

English (en)

Other versions

DE69700470T2 (de

Inventor

Alain Piasco

Jean Lafay

Remi Delansorne

Jacques Paris

Jean-Claude Pascal

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Laboratoire Theramex SAM

Original Assignee

Laboratoire Theramex SAM

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-01-22

Filing date

1997-01-17

Publication date

1999-10-07

1997-01-17 Application filed by Laboratoire Theramex SAM filed Critical Laboratoire Theramex SAM

1999-10-07 Publication of DE69700470D1 publication Critical patent/DE69700470D1/de

2000-03-30 Application granted granted Critical

2000-03-30 Publication of DE69700470T2 publication Critical patent/DE69700470T2/de

2017-01-18 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
- C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
- C07J7/004—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa
- C07J7/0045—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa not substituted in position 16
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/34—Gestagens
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J21/005—Ketals
- C07J21/006—Ketals at position 3
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
- C07J41/0016—Oximes
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
- C07J53/002—Carbocyclic rings fused
- C07J53/004—3 membered carbocyclic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/001—Oxiranes

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Endocrinology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Reproductive Health (AREA)
Diabetes (AREA)
Gynecology & Obstetrics (AREA)
Pregnancy & Childbirth (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Saccharide Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

DE69700470T 1996-01-22 1997-01-17 Neue 19-nor-pregnen-derivate Expired - Lifetime DE69700470T2 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP96400146A EP0785212A1 (de)	1996-01-22	1996-01-22	Neue 19-nor-Pregnan-Derivate
PCT/EP1997/000357 WO1997027210A1 (en)	1996-01-22	1997-01-17	New 19-nor-pregnene derivatives

Publications (2)

Publication Number	Publication Date
DE69700470D1 true DE69700470D1 (de)	1999-10-07
DE69700470T2 DE69700470T2 (de)	2000-03-30

Family

ID=8225217

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE69700470T Expired - Lifetime DE69700470T2 (de)	1996-01-22	1997-01-17	Neue 19-nor-pregnen-derivate

Country Status (35)

Country	Link
US (1)	US6180803B1 (de)
EP (2)	EP0785212A1 (de)
JP (2)	JP4368945B2 (de)
KR (1)	KR100396902B1 (de)
CN (1)	CN1187366C (de)
AP (1)	AP1176A (de)
AR (1)	AR005500A1 (de)
AT (1)	ATE184015T1 (de)
BR (1)	BR9707064A (de)
CA (1)	CA2243504C (de)
CO (1)	CO4810230A1 (de)
CZ (1)	CZ292047B6 (de)
DE (1)	DE69700470T2 (de)
DZ (1)	DZ2169A1 (de)
EE (1)	EE03692B1 (de)
ES (1)	ES2140961T3 (de)
GR (1)	GR3031954T3 (de)
HU (1)	HU221796B1 (de)
ID (1)	ID15840A (de)
IL (1)	IL125379A (de)
IS (1)	IS1902B (de)
JO (1)	JO1971B1 (de)
MY (1)	MY116845A (de)
NO (1)	NO309572B1 (de)
NZ (1)	NZ330954A (de)
OA (1)	OA10813A (de)
PE (1)	PE55998A1 (de)
PL (1)	PL185608B1 (de)
RU (1)	RU2166509C2 (de)
SI (1)	SI0886645T1 (de)
TN (1)	TNSN97015A1 (de)
TR (1)	TR199801399T2 (de)
TW (1)	TW411345B (de)
WO (1)	WO1997027210A1 (de)
ZA (1)	ZA97521B (de)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2776191B1 (fr) *	1998-03-23	2002-05-31	Theramex	Composition hormonale topique a effet systemique
TWI290549B (en) *	2000-06-02	2007-12-01	Astrazeneca Ab	Process for the preparation of cyclopropyl carboxylic acid ester and derivatives
AU8206401A (en)	2000-08-03	2002-02-18	Antares Pharma Ipl Ag	Novel composition for transdermal and/or transmucosal administration of active compounds that ensures adequate therapeutic levels
US8980290B2 (en)	2000-08-03	2015-03-17	Antares Pharma Ipl Ag	Transdermal compositions for anticholinergic agents
US20070225379A1 (en) *	2001-08-03	2007-09-27	Carrara Dario Norberto R	Transdermal delivery of systemically active central nervous system drugs
US7198801B2 (en)	2000-08-03	2007-04-03	Antares Pharma Ipl Ag	Formulations for transdermal or transmucosal application
US20040198706A1 (en) *	2003-03-11	2004-10-07	Carrara Dario Norberto R.	Methods and formulations for transdermal or transmucosal application of active agents
FR2814074B1 (fr) *	2000-09-15	2003-03-07	Theramex	Nouvelles compositions estro-progestatives topiques a effet systemique
DK1660009T3 (en)	2003-09-03	2015-04-27	Miscon Trading S A	METHODS OF TREATING ENDOMETRIOSIS
PL1670433T3 (pl)	2003-10-10	2013-03-29	Ferring Bv	Przezskórna formulacja farmaceutyczna do zmniejszania pozostałości na skórze
US7425340B2 (en)	2004-05-07	2008-09-16	Antares Pharma Ipl Ag	Permeation enhancing compositions for anticholinergic agents
US8067399B2 (en)	2005-05-27	2011-11-29	Antares Pharma Ipl Ag	Method and apparatus for transdermal or transmucosal application of testosterone
CA2646667C (en)	2006-04-21	2014-03-11	Antares Pharma Ipl Ag	Methods of treating hot flashes with formulations for transdermal or transmucosal application
WO2008067991A2 (en) *	2006-12-08	2008-06-12	Antares Pharma Ipl Ag	Skin-friendly drug complexes for transdermal administration
LT2782584T (lt)	2011-11-23	2021-09-10	Therapeuticsmd, Inc.	Natūralios kombinuotos pakaitinės hormonų terapijos kompozicijos ir gydymas
US9301920B2 (en)	2012-06-18	2016-04-05	Therapeuticsmd, Inc.	Natural combination hormone replacement formulations and therapies
US10806697B2 (en)	2012-12-21	2020-10-20	Therapeuticsmd, Inc.	Vaginal inserted estradiol pharmaceutical compositions and methods
US20150196640A1 (en)	2012-06-18	2015-07-16	Therapeuticsmd, Inc.	Progesterone formulations having a desirable pk profile
US10806740B2 (en)	2012-06-18	2020-10-20	Therapeuticsmd, Inc.	Natural combination hormone replacement formulations and therapies
US20130338122A1 (en)	2012-06-18	2013-12-19	Therapeuticsmd, Inc.	Transdermal hormone replacement therapies
US9180091B2 (en)	2012-12-21	2015-11-10	Therapeuticsmd, Inc.	Soluble estradiol capsule for vaginal insertion
US10568891B2 (en)	2012-12-21	2020-02-25	Therapeuticsmd, Inc.	Vaginal inserted estradiol pharmaceutical compositions and methods
US11246875B2 (en)	2012-12-21	2022-02-15	Therapeuticsmd, Inc.	Vaginal inserted estradiol pharmaceutical compositions and methods
US10537581B2 (en)	2012-12-21	2020-01-21	Therapeuticsmd, Inc.	Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en)	2012-12-21	2022-03-08	Therapeuticsmd, Inc.	Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en)	2012-12-21	2019-11-12	Therapeuticsmd, Inc.	Vaginal inserted estradiol pharmaceutical compositions and methods
US10206932B2 (en)	2014-05-22	2019-02-19	Therapeuticsmd, Inc.	Natural combination hormone replacement formulations and therapies
US9173915B1 (en) *	2014-10-10	2015-11-03	Peter F. Kador	Antioxidant eye drops
US10328087B2 (en)	2015-07-23	2019-06-25	Therapeuticsmd, Inc.	Formulations for solubilizing hormones
CN109481450B (zh) *	2015-09-02	2021-07-23	盛世泰科生物医药技术(苏州)有限公司	一种用于预防和治疗白内障的眼用制剂及其制备方法
WO2017173044A1 (en)	2016-04-01	2017-10-05	Therapeuticsmd Inc.	Steroid hormone compositions in medium chain oils
JP2019513709A (ja)	2016-04-01	2019-05-30	セラピューティックスエムディーインコーポレーテッドＴｈｅｒａｐｅｕｔｉｃｓｍｄ，Ｉｎｃ．	ステロイドホルモン薬学的組成物
CN110452279B (zh) *	2019-05-13	2022-04-08	株洲千金药业股份有限公司	三萜类化合物和其药学上可接受的盐及制备方法和应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1593524A1 (de) *	1951-01-28	1970-08-13	Schering Ag	Verfahren zur Herstellung von 1,2alpha-Methylen-19-nor-steroiden
DE1087127B (de) *	1958-12-13	1960-08-18	Schering Ag	Verfahren zur Herstellung neuer progestativ wirksamer Ester von 2-Methyl-Steroiden
FR1405214A (fr) *	1962-06-21	1965-07-09	Rhone Poulenc Sa	Nouveaux stéroïdes de la série du prégnane et leur procédé de préparation
FR1525916A (fr) *	1965-11-09	1968-05-24	Schering Ag	Stéroïdes portant un groupe méthylène en position 1.2 et leur préparation
US3835160A (en) *	1967-06-06	1974-09-10	Schering Corp	3{40 -keto-2{40 ,3{40 -seco-1{40 -(2{40 )-yne steroidal derivatives, methods for their manufacture, and compounds produced thereby
US3891677A (en) *	1967-06-06	1975-06-24	Schering Corp	17{60 ,20,20,21-Bismethylenedioxy-4,5-seco-3-pregnyne-5-ones
BE757286A (fr) *	1969-10-10	1971-04-09	Ciba Geigy	Nouvelle 6alpha-methyl-19-nor progesterone et procede pour sa preparation
CH538462A (de) *	1970-10-07	1973-06-30	Ciba Geigy Ag	Ein neues Verfahren zur Herstellung von 6a-Methyl-19-nor-pregnenen
DE3402330A1 (de) *	1984-01-20	1985-07-25	Schering AG, 1000 Berlin und 4709 Bergkamen	1(alpha),2(alpha)-methylen-6-methylen- und 6(alpha)-methyl-pregnene, verfahren zu deren herstellung und diese enthaltende pharmazeutische praeparate
US5395831A (en) *	1994-04-08	1995-03-07	American Home Products Corporation	Treating cardiac disorders with Δ9(11)-dehydro-8-isoestrone

1996
- 1996-01-22 EP EP96400146A patent/EP0785212A1/de not_active Withdrawn
1997
- 1997-01-17 PL PL97327998A patent/PL185608B1/pl not_active IP Right Cessation
- 1997-01-17 ES ES97902235T patent/ES2140961T3/es not_active Expired - Lifetime
- 1997-01-17 JP JP52656697A patent/JP4368945B2/ja not_active Expired - Fee Related
- 1997-01-17 US US09/101,775 patent/US6180803B1/en not_active Expired - Fee Related
- 1997-01-17 CA CA002243504A patent/CA2243504C/en not_active Expired - Fee Related
- 1997-01-17 CZ CZ19982307A patent/CZ292047B6/cs not_active IP Right Cessation
- 1997-01-17 HU HU9900684A patent/HU221796B1/hu not_active IP Right Cessation
- 1997-01-17 WO PCT/EP1997/000357 patent/WO1997027210A1/en not_active Ceased
- 1997-01-17 NZ NZ330954A patent/NZ330954A/xx not_active IP Right Cessation
- 1997-01-17 AP APAP/P/1998/001299A patent/AP1176A/en active
- 1997-01-17 SI SI9730015T patent/SI0886645T1/xx not_active IP Right Cessation
- 1997-01-17 BR BR9707064-5A patent/BR9707064A/pt not_active Application Discontinuation
- 1997-01-17 IL IL12537997A patent/IL125379A/xx not_active IP Right Cessation
- 1997-01-17 AT AT97902235T patent/ATE184015T1/de active
- 1997-01-17 TR TR1998/01399T patent/TR199801399T2/xx unknown
- 1997-01-17 EP EP97902235A patent/EP0886645B1/de not_active Expired - Lifetime
- 1997-01-17 DE DE69700470T patent/DE69700470T2/de not_active Expired - Lifetime
- 1997-01-17 EE EE9800219A patent/EE03692B1/xx not_active IP Right Cessation
- 1997-01-17 KR KR10-1998-0705607A patent/KR100396902B1/ko not_active Expired - Fee Related
- 1997-01-17 CN CNB971918228A patent/CN1187366C/zh not_active Expired - Fee Related
- 1997-01-17 RU RU98115774/04A patent/RU2166509C2/ru not_active IP Right Cessation
- 1997-01-18 TW TW086100511A patent/TW411345B/zh not_active IP Right Cessation
- 1997-01-21 JO JO19971971A patent/JO1971B1/en active
- 1997-01-21 DZ DZ970014A patent/DZ2169A1/fr active
- 1997-01-21 CO CO97002478A patent/CO4810230A1/es unknown
- 1997-01-21 AR ARP970100228A patent/AR005500A1/es active IP Right Grant
- 1997-01-21 MY MYPI97000215A patent/MY116845A/en unknown
- 1997-01-21 TN TNTNSN97015A patent/TNSN97015A1/fr unknown
- 1997-01-22 ZA ZA9700521A patent/ZA97521B/xx unknown
- 1997-01-22 PE PE1997000035A patent/PE55998A1/es not_active Application Discontinuation
- 1997-01-22 ID IDP970175A patent/ID15840A/id unknown
1998
- 1998-07-21 IS IS4800A patent/IS1902B/is unknown
- 1998-07-21 NO NO983356A patent/NO309572B1/no not_active IP Right Cessation
- 1998-07-22 OA OA9800117A patent/OA10813A/en unknown
1999
- 1999-11-25 GR GR990403047T patent/GR3031954T3/el unknown
2009
- 2009-02-04 JP JP2009024075A patent/JP2009167188A/ja not_active Withdrawn

Also Published As

Publication number	Publication date
CN1209811A (zh)	1999-03-03
NO309572B1 (no)	2001-02-19
OA10813A (en)	2003-01-28
IS4800A (is)	1998-07-21
DZ2169A1 (fr)	2002-12-25
EP0886645A1 (de)	1998-12-30
IS1902B (is)	2003-11-20
HU221796B1 (hu)	2003-01-28
CZ292047B6 (cs)	2003-07-16
HK1018216A1 (en)	1999-12-17
PE55998A1 (es)	1998-10-01
JP4368945B2 (ja)	2009-11-18
TNSN97015A1 (fr)	2005-03-15
DE69700470T2 (de)	2000-03-30
JO1971B1 (en)	1997-12-15
KR100396902B1 (ko)	2004-05-03
CN1187366C (zh)	2005-02-02
TR199801399T2 (xx)	1998-10-21
PL185608B1 (pl)	2003-06-30
TW411345B (en)	2000-11-11
NO983356D0 (no)	1998-07-21
WO1997027210A1 (en)	1997-07-31
RU2166509C2 (ru)	2001-05-10
HUP9900684A3 (en)	1999-11-29
EE9800219A (xx)	1998-12-15
GR3031954T3 (en)	2000-03-31
ID15840A (id)	1997-08-14
AU1595597A (en)	1997-08-20
IL125379A (en)	2003-05-29
JP2000503980A (ja)	2000-04-04
CO4810230A1 (es)	1999-06-30
KR19990081895A (ko)	1999-11-15
CA2243504A1 (en)	1997-07-31
NO983356L (no)	1998-07-21
AP9801299A0 (en)	1998-09-30
AU708135B2 (en)	1999-07-29
ZA97521B (en)	1997-08-04
EE03692B1 (et)	2002-04-15
CA2243504C (en)	2004-03-30
JP2009167188A (ja)	2009-07-30
AR005500A1 (es)	1999-06-23
PL327998A1 (en)	1999-01-04
HUP9900684A2 (hu)	1999-07-28
US6180803B1 (en)	2001-01-30
MY116845A (en)	2004-04-30
EP0785212A1 (de)	1997-07-23
CZ230798A3 (cs)	1998-11-11
NZ330954A (en)	1998-10-28
ATE184015T1 (de)	1999-09-15
SI0886645T1 (en)	1999-12-31
IL125379A0 (en)	1999-03-12
BR9707064A (pt)	1999-12-28
EP0886645B1 (de)	1999-09-01
ES2140961T3 (es)	2000-03-01
AP1176A (en)	2003-06-30

Publication	Publication Date	Title
DE69700470D1 (de)	1999-10-07	Neue 19-nor-pregnen-derivate
DE69635700D1 (de)	2006-03-30	Neue endoglukanase
DE69635284D1 (de)	2006-02-23	Neue substituierte napthopyrane
NO971041D0 (no)	1997-03-06	Brönn-frakoplingsverktöy
EP0913191A4 (de)	1999-11-17	Mikroemulsion
ID18010A (id)	1998-02-19	Oligosakarida termodifikasi
DE69536102D1 (de)	2010-10-21	Neue streptogramine
NO992059D0 (no)	1999-04-29	2-metoksyfenylpiperazinderivater
IT1284701B1 (it)	1998-05-21	Serratura perfezionata
DE69622801D1 (de)	2002-09-12	Neue carbapenemderivate
DE59711090D1 (de)	2004-01-22	Türrahmen
DE69718527D1 (de)	2003-02-27	Neue Hexokinase
DK0778390T3 (da)	2004-02-09	Drejeslag-sneglebor
BR9711681A (pt)	1999-08-24	Novos m-todos
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FI965275A0 (fi)	1996-12-31	Aonglaoda i kartong- eller pappersmaskin
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