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DE69630324D1 - Verfahren und Kristallformen von 2-Methylthienobenzodiazepinen - Google Patents

Verfahren und Kristallformen von 2-Methylthienobenzodiazepinen

Info

Publication number
DE69630324D1
DE69630324D1 DE69630324T DE69630324T DE69630324D1 DE 69630324 D1 DE69630324 D1 DE 69630324D1 DE 69630324 T DE69630324 T DE 69630324T DE 69630324 T DE69630324 T DE 69630324T DE 69630324 D1 DE69630324 D1 DE 69630324D1
Authority
DE
Germany
Prior art keywords
methylthienobenzodiazepines
crystal forms
crystal
forms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69630324T
Other languages
English (en)
Other versions
DE69630324T2 (de
Inventor
Charles Arthur Bunnell
Barry Arnold Hendriksen
Samuel Dean Larsen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co Ltd
Eli Lilly and Co
Original Assignee
Eli Lilly and Co Ltd
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23621056&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69630324(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Eli Lilly and Co Ltd, Eli Lilly and Co filed Critical Eli Lilly and Co Ltd
Application granted granted Critical
Publication of DE69630324D1 publication Critical patent/DE69630324D1/de
Publication of DE69630324T2 publication Critical patent/DE69630324T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicinal Preparation (AREA)
DE69630324T 1995-03-24 1996-03-22 Verfahren und Kristallformen von 2-Methylthienobenzodiazepinen Expired - Lifetime DE69630324T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US40956695A 1995-03-24 1995-03-24
US409566 1995-03-24

Publications (2)

Publication Number Publication Date
DE69630324D1 true DE69630324D1 (de) 2003-11-13
DE69630324T2 DE69630324T2 (de) 2004-07-29

Family

ID=23621056

Family Applications (4)

Application Number Title Priority Date Filing Date
DE69614426T Expired - Lifetime DE69614426T2 (de) 1995-03-24 1996-03-22 Kristallformen eines Thieno(2,3-B)(1,5)benzodiazepinderivates und Verfahren zu deren Herstellung
DE69630324T Expired - Lifetime DE69630324T2 (de) 1995-03-24 1996-03-22 Verfahren und Kristallformen von 2-Methylthienobenzodiazepinen
DE19681286T Withdrawn DE19681286T1 (de) 1995-03-24 1996-03-22 Neue Kristallform von Olanzapin
DE69636313T Expired - Lifetime DE69636313T2 (de) 1995-03-24 1996-03-22 Verwendung von Kristallformen von 2-Methylthienobenzodiazepinen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE69614426T Expired - Lifetime DE69614426T2 (de) 1995-03-24 1996-03-22 Kristallformen eines Thieno(2,3-B)(1,5)benzodiazepinderivates und Verfahren zu deren Herstellung

Family Applications After (2)

Application Number Title Priority Date Filing Date
DE19681286T Withdrawn DE19681286T1 (de) 1995-03-24 1996-03-22 Neue Kristallform von Olanzapin
DE69636313T Expired - Lifetime DE69636313T2 (de) 1995-03-24 1996-03-22 Verwendung von Kristallformen von 2-Methylthienobenzodiazepinen

Country Status (48)

Country Link
US (1) US5736541A (de)
EP (3) EP0733635B1 (de)
JP (1) JPH11502535A (de)
KR (1) KR100399688B1 (de)
CN (1) CN1065536C (de)
AP (1) AP828A (de)
AR (2) AR002719A1 (de)
AT (4) ATE331719T1 (de)
AU (1) AU706471B2 (de)
BG (1) BG62619B1 (de)
BR (1) BR9607790A (de)
CA (1) CA2214005C (de)
CH (1) CH690579A5 (de)
CO (1) CO4650278A1 (de)
CZ (1) CZ292688B6 (de)
DE (4) DE69614426T2 (de)
DK (4) DK0733635T3 (de)
EA (1) EA000149B1 (de)
EE (1) EE03489B1 (de)
EG (1) EG23659A (de)
ES (3) ES2208220T3 (de)
FI (1) FI973750L (de)
GB (1) GB2313835B (de)
HU (1) HU224989B1 (de)
IL (1) IL117610A (de)
IS (1) IS1896B (de)
LT (1) LT4349B (de)
LU (1) LU90096B1 (de)
LV (1) LV12018B (de)
MY (1) MY114701A (de)
NO (1) NO314663B1 (de)
NZ (1) NZ306110A (de)
OA (1) OA10510A (de)
PA (1) PA8353701A1 (de)
PE (1) PE44897A1 (de)
PL (1) PL183723B1 (de)
PT (3) PT1095941E (de)
RO (1) RO118872B1 (de)
SE (1) SE9703205L (de)
SI (4) SI9620040B (de)
SK (1) SK284143B6 (de)
SV (1) SV1996000031A (de)
TR (1) TR199701017T1 (de)
TW (2) TW513432B (de)
UA (1) UA44765C2 (de)
WO (1) WO1996030375A1 (de)
YU (1) YU49478B (de)
ZA (2) ZA962342B (de)

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UA57727C2 (uk) * 1996-03-11 2003-07-15 Елі Ліллі Енд Компані Спосіб лікування надмірної агресивності
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CZ302367B6 (cs) * 1998-09-30 2011-04-13 Eli Lilly And Company 2-Methylthienobenzodiazepinový prípravek
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Also Published As

Publication number Publication date
LU90096B1 (fr) 1997-07-22
CA2214005C (en) 2001-07-03
NO314663B1 (no) 2003-04-28
SV1996000031A (es) 1998-03-27
SE9703205D0 (sv) 1997-09-05
ES2208220T3 (es) 2004-06-16
YU17796A (sh) 1999-03-04
IS1896B (is) 2003-10-20
NO974365L (no) 1997-09-22
DE69614426T2 (de) 2002-05-23
RO118872B1 (ro) 2003-12-30
AU706471B2 (en) 1999-06-17
HUP9802824A2 (hu) 1999-06-28
JPH11502535A (ja) 1999-03-02
FI973750A7 (fi) 1997-09-22
AU5427996A (en) 1996-10-16
ATE251627T1 (de) 2003-10-15
CA2214005A1 (en) 1996-10-03
SI0733635T1 (en) 2002-06-30
IL117610A (en) 2001-08-26
EP0733635A1 (de) 1996-09-25
ES2266719T3 (es) 2007-03-01
SE9703205L (sv) 1997-09-05
GB2313835A (en) 1997-12-10
ATE331719T1 (de) 2006-07-15
NZ306110A (en) 1998-09-24
TW442488B (en) 2001-06-23
AR002719A1 (es) 1998-04-29
KR19980703188A (ko) 1998-10-15
HU224989B1 (en) 2006-05-29
PA8353701A1 (es) 1998-09-18
PT1445259E (pt) 2006-10-31
DK1095941T3 (da) 2004-02-16
PT1095941E (pt) 2004-02-27
HUP9802824A3 (en) 2000-01-28
LV12018A (lv) 1998-04-20
CO4650278A1 (es) 1998-09-03
NO974365D0 (no) 1997-09-22
WO1996030375A1 (en) 1996-10-03
CN1179160A (zh) 1998-04-15
GB9719819D0 (en) 1997-11-19
LV12018B (en) 1998-09-20
EE03489B1 (et) 2001-08-15
MX9707183A (es) 1997-11-29
EP1095941A1 (de) 2001-05-02
SI1445259T1 (sl) 2006-10-31
HK1013988A1 (en) 1999-09-17
DE69630324T2 (de) 2004-07-29
SI1095941T1 (en) 2003-12-31
AT406771B (de) 2000-08-25
EG23659A (en) 2007-03-26
US5736541A (en) 1998-04-07
EP0733635B1 (de) 2001-08-16
EP1095941B1 (de) 2003-10-08
DE19681286T1 (de) 1998-04-02
UA44765C2 (uk) 2002-03-15
GB2313835B (en) 1998-09-16
CZ300097A3 (en) 1997-12-17
YU49478B (sh) 2006-05-25
PL322501A1 (en) 1998-02-02
DK108997A (da) 1997-11-12
BG101900A (en) 1999-03-31
BG62619B1 (bg) 2000-03-31
AP9701065A0 (en) 1997-10-31
AR010448A1 (es) 2000-06-28
LT4349B (lt) 1998-05-25
IL117610A0 (en) 1996-07-23
PL183723B1 (pl) 2002-07-31
BR9607790A (pt) 1998-07-07
PE44897A1 (es) 1997-10-22
EE9700232A (et) 1998-04-15
ATE204280T1 (de) 2001-09-15
KR100399688B1 (ko) 2004-02-18
DK0733635T3 (da) 2001-10-08
FI973750A0 (fi) 1997-09-22
DE69636313T2 (de) 2007-05-31
OA10510A (en) 2002-04-24
DE69636313D1 (de) 2006-08-10
EA199700262A1 (ru) 1998-02-26
LT97148A (lt) 1998-01-26
IS4564A (is) 1997-09-22
SK284143B6 (sk) 2004-10-05
DK1445259T3 (da) 2006-10-16
ATA902196A (de) 2000-01-15
EA000149B1 (ru) 1998-10-29
TW513432B (en) 2002-12-11
TR199701017T1 (xx) 1998-01-21
PT733635E (pt) 2001-12-28
ZA962342B (en) 1997-09-22
SK121897A3 (en) 1998-03-04
CH690579A5 (de) 2000-10-31
EP1445259B1 (de) 2006-06-28
AP828A (en) 2000-04-28
EP1445259A1 (de) 2004-08-11
SI9620040B (sl) 2002-02-28
DE69614426D1 (de) 2001-09-20
SI9620040A (sl) 1998-06-30
ES2159346T3 (es) 2001-10-01
CZ292688B6 (cs) 2003-11-12
MY114701A (en) 2002-12-31
FI973750L (fi) 1997-09-22
ZA962344B (en) 1997-09-22
CN1065536C (zh) 2001-05-09

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