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DE69626984D1 - Ionenkanal - Google Patents

Ionenkanal

Info

Publication number
DE69626984D1
DE69626984D1 DE69626984T DE69626984T DE69626984D1 DE 69626984 D1 DE69626984 D1 DE 69626984D1 DE 69626984 T DE69626984 T DE 69626984T DE 69626984 T DE69626984 T DE 69626984T DE 69626984 D1 DE69626984 D1 DE 69626984D1
Authority
DE
Germany
Prior art keywords
sodium channel
novel
ion channel
tetrodotoxin
pain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Revoked
Application number
DE69626984T
Other languages
English (en)
Other versions
DE69626984T2 (de
Inventor
Nicholas Wood
Norakovitch Akopian
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ionix Pharmaceuticals Ltd
Original Assignee
Ionix Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10776812&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69626984(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ionix Pharmaceuticals Ltd filed Critical Ionix Pharmaceuticals Ltd
Application granted granted Critical
Publication of DE69626984D1 publication Critical patent/DE69626984D1/de
Publication of DE69626984T2 publication Critical patent/DE69626984T2/de
Anticipated expiration legal-status Critical
Revoked legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/9486—Analgesics, e.g. opiates, aspirine
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Optical Communication System (AREA)
  • Surface Acoustic Wave Elements And Circuit Networks Thereof (AREA)
  • Thin Film Transistor (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE69626984T 1995-06-28 1996-06-25 Ionenkanal Revoked DE69626984T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9513180.1A GB9513180D0 (en) 1995-06-28 1995-06-28 Ion channel
PCT/GB1996/001523 WO1997001577A1 (en) 1995-06-28 1996-06-25 Ion channel

Publications (2)

Publication Number Publication Date
DE69626984D1 true DE69626984D1 (de) 2003-04-30
DE69626984T2 DE69626984T2 (de) 2003-12-18

Family

ID=10776812

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69626984T Revoked DE69626984T2 (de) 1995-06-28 1996-06-25 Ionenkanal

Country Status (12)

Country Link
US (3) US6451554B1 (de)
EP (2) EP0835261B1 (de)
JP (1) JPH11509090A (de)
AT (1) ATE235512T1 (de)
AU (1) AU721798B2 (de)
CA (1) CA2221294A1 (de)
DE (1) DE69626984T2 (de)
DK (1) DK0835261T3 (de)
ES (1) ES2196158T3 (de)
GB (1) GB9513180D0 (de)
PT (1) PT835261E (de)
WO (1) WO1997001577A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9513180D0 (en) * 1995-06-28 1995-08-30 Univ London Ion channel
US6184349B1 (en) 1995-10-11 2001-02-06 Syntex (Usa) Inc. Cloned peripheral nerve, tetrodotoxin-resistant sodium channel α-subunit
US6030810A (en) * 1997-02-26 2000-02-29 Delgado; Stephen Gregory Cloned tetrodotoxin-sensitive sodium channel α-subunit and a splice variant thereof
EP0884386A1 (de) * 1997-05-30 1998-12-16 Synthelabo Natrium-Ionenkanäle Rezeptor
AU9732498A (en) * 1997-10-29 1999-05-17 Mcgill University Dna encoding a human proton-gated ion channel and uses thereof
CH693031A5 (de) * 1997-11-20 2003-01-31 Hoffmann La Roche Nucleinsäure, die einen Nervengewebe-Natriumkanal kodiert.
AU1466199A (en) * 1997-11-20 1999-06-15 Medical College Of Georgia Research Institute, Inc. Cloning of a tetrodotoxin-resistant sodium channel alpha-subunit
US6573067B1 (en) 1998-01-29 2003-06-03 Yale University Nucleic acid encoding sodium channels in dorsal root ganglia
WO1999038889A2 (en) * 1998-01-29 1999-08-05 Yale University Modulation of sodium channels in dorsal root ganglia
GB9805793D0 (en) * 1998-03-18 1998-05-13 Glaxo Group Ltd Sodium ion channels
US20030228666A1 (en) * 1998-06-30 2003-12-11 Daewoong Pharmaceutical Co., Ltd. Novel human thrombopoietin mutein
DE1252330T1 (de) * 1999-11-26 2003-11-27 Mcgill University, Montreal Loci der idiopathischen epilepsie, mutationen derselben und verfahren zu deren verwendung zur feststellung, prognose und behandlung von epilepsie
GB0006024D0 (en) * 2000-03-14 2000-05-03 Glaxo Group Ltd Altered ion channel proteins
WO2002002608A2 (en) * 2000-07-05 2002-01-10 Neurosearch A/S NEW SODIUM CHANNEL (rNaV1.5a) AND USE THEREOF
JP4701374B2 (ja) * 2000-08-04 2011-06-15 大学共同利用機関法人自然科学研究機構 ＮａＶ２チャネル遺伝子欠損非ヒト動物
CN1269482C (zh) * 2001-05-18 2006-08-16 威克斯医药有限公司 钠离子通道阻断剂和阿片类镇痛剂在制备用于对哺乳动物进行协同镇痛的药物中的应用
GB0120238D0 (en) * 2001-08-20 2001-10-10 Univ College Of London Sodium channel regulators and modulators
WO2003072751A2 (en) 2002-02-25 2003-09-04 Vanderbilt University Expression system for human brain-specific voltage-gated sodium channel, type 1
GB0211833D0 (en) * 2002-05-22 2002-07-03 Univ London Sodium channel regulators and modulators
WO2004087956A2 (en) * 2003-04-02 2004-10-14 Ionix Pharmaceuticals Limited Cell lines for the functional expression of nav1.8
WO2005086934A2 (en) * 2004-03-10 2005-09-22 Board Of Regents, The University Of Texas System Enriched cdna expression libraries and methods of making and using same
MX2007005069A (es) 2004-10-27 2007-06-25 Schering Corp Composiciones y metodos para la inhibicion del acido nucleico corto de interferencia de nav1.8.
EP2167643A4 (de) 2007-06-08 2010-06-16 Senomyx Inc Identifikation von trpml3 (mcoln3) als salziger geschmacksrezeptor und seine verwendung in assays zur identifikation von (salzigen) modulatoren und/oder therapeutika zur modulierung von natrium-transport, -absorption oder ausscheidung und/oder zur aldosteron- und/oder vasopressin-herstellung oder -freisetzung
CN105445476B (zh) * 2015-12-17 2018-03-23 中山大学中山眼科中心 一种基于组织支架的三维视杯来源神经样细胞的钠离子通道检测方法
US20240376176A1 (en) * 2021-07-08 2024-11-14 Children's Medical Center Corporation Systems and methods for delivery based on supramolecular nanostructures

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990009391A1 (en) 1989-02-13 1990-08-23 Arch Development Corporation Nucleic acid encoding sodium channel protein
US5380836A (en) 1989-02-13 1995-01-10 Arch Development Corporation Nucleic acid encoding sodium channel protein
GB9513180D0 (en) * 1995-06-28 1995-08-30 Univ London Ion channel
US6184349B1 (en) * 1995-10-11 2001-02-06 Syntex (Usa) Inc. Cloned peripheral nerve, tetrodotoxin-resistant sodium channel α-subunit

Also Published As

Publication number Publication date
DE69626984T2 (de) 2003-12-18
US6451554B1 (en) 2002-09-17
ES2196158T3 (es) 2003-12-16
EP1281717A2 (de) 2003-02-05
EP0835261B1 (de) 2003-03-26
GB9513180D0 (en) 1995-08-30
CA2221294A1 (en) 1997-01-16
AU721798B2 (en) 2000-07-13
JPH11509090A (ja) 1999-08-17
US7112418B2 (en) 2006-09-26
AU6234596A (en) 1997-01-30
PT835261E (pt) 2003-08-29
US20050221394A1 (en) 2005-10-06
ATE235512T1 (de) 2003-04-15
EP1281717A3 (de) 2003-04-23
DK0835261T3 (da) 2003-07-21
EP0835261A1 (de) 1998-04-15
WO1997001577A1 (en) 1997-01-16
US20030176648A1 (en) 2003-09-18

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Legal Events

Date Code Title Description
8363 Opposition against the patent
8331 Complete revocation