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DE69625354D1 - Relaxinartiger faktor und damit zusammenhängende verfahren und verwendungen - Google Patents

Relaxinartiger faktor und damit zusammenhängende verfahren und verwendungen

Info

Publication number
DE69625354D1
DE69625354D1 DE69625354T DE69625354T DE69625354D1 DE 69625354 D1 DE69625354 D1 DE 69625354D1 DE 69625354 T DE69625354 T DE 69625354T DE 69625354 T DE69625354 T DE 69625354T DE 69625354 D1 DE69625354 D1 DE 69625354D1
Authority
DE
Germany
Prior art keywords
relaxin
factor
related methods
analogs
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69625354T
Other languages
English (en)
Other versions
DE69625354T2 (de
Inventor
Christian Schwabe
Elaine Unemori
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of South Carolina
Medical University of South Carolina MUSC
Connective Therapeutics Inc
Original Assignee
University of South Carolina
Medical University of South Carolina MUSC
Connective Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of South Carolina, Medical University of South Carolina MUSC, Connective Therapeutics Inc filed Critical University of South Carolina
Application granted granted Critical
Publication of DE69625354D1 publication Critical patent/DE69625354D1/de
Publication of DE69625354T2 publication Critical patent/DE69625354T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/64—Relaxins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Rheumatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE69625354T 1995-06-07 1996-05-16 Relaxinartiger faktor und damit zusammenhängende verfahren und verwendungen Expired - Lifetime DE69625354T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/484,219 US5911997A (en) 1995-06-07 1995-06-07 Relaxin-like factor and methods and uses thereof
PCT/US1996/007399 WO1996040186A1 (en) 1995-06-07 1996-05-16 Relaxin-like factor and methods and uses thereof

Publications (2)

Publication Number Publication Date
DE69625354D1 true DE69625354D1 (de) 2003-01-23
DE69625354T2 DE69625354T2 (de) 2003-10-30

Family

ID=23923245

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69625354T Expired - Lifetime DE69625354T2 (de) 1995-06-07 1996-05-16 Relaxinartiger faktor und damit zusammenhängende verfahren und verwendungen

Country Status (9)

Country Link
US (2) US5911997A (de)
EP (1) EP0831871B1 (de)
JP (1) JP3830520B2 (de)
AT (1) ATE229340T1 (de)
AU (1) AU709115B2 (de)
CA (1) CA2224080C (de)
DE (1) DE69625354T2 (de)
ES (1) ES2188763T3 (de)
WO (1) WO1996040186A1 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6777196A (en) 1995-08-15 1997-03-12 Connective Therapeutics Inc. Method of promoting angiogenesis
DE19641378C1 (de) * 1996-09-27 1998-04-02 Ihf Inst Fuer Hormon Und Fortp Diagnosehilfe sowie Verfahren zum Nachweis der Trächtigkeit von Wiederkäuern
GB9717652D0 (en) * 1997-08-20 1997-10-22 Nycomed Imaging As Method
AUPR814401A0 (en) 2001-10-08 2001-11-01 Howard Florey Institute Of Experimental Physiology And Medicine Human 3 relaxin
US20050186526A1 (en) * 2002-11-01 2005-08-25 Bas Medical, Inc. Methods and systems for enabling and stabilizing tooth movement
AU2003903124A0 (en) * 2003-06-20 2003-07-10 Mark Del Borgo Analogues of heteromeric proteins
US7878978B2 (en) * 2004-03-18 2011-02-01 University Of Pittsburgh- Of The Commonwealth System Of Higher Education Use of relaxin to increase arterial compliance
AU2005247332A1 (en) * 2004-04-30 2005-12-08 Corthera, Inc. Methods and compositions for control of fetal growth via modulation of relaxin
US20060052304A1 (en) * 2004-09-02 2006-03-09 Bas Medical, Inc. Method for remodeling bone and related sutures
EP1984016A1 (de) * 2006-02-17 2008-10-29 Associazione Foresta Per La Ricerca Nella Riproduzione Umana Verwendung von insulin-artigem faktor 3 zur behandlung von osteoporose und knochenerkrankungen
CN102224420B (zh) * 2008-11-24 2014-09-17 科尔泰拉公司 先兆子痫的预测和预防
AU2011291943B2 (en) 2010-08-17 2015-01-22 Ambrx, Inc. Modified relaxin polypeptides and their uses
US9567386B2 (en) 2010-08-17 2017-02-14 Ambrx, Inc. Therapeutic uses of modified relaxin polypeptides
CA2842395A1 (en) * 2011-08-04 2013-02-07 Pharis Biotec Gmbh Process for preparing human relaxin-2
WO2013177529A1 (en) * 2012-05-24 2013-11-28 Angion Biomedica Corp. Relaxin-like compounds and uses thereof
US9393288B2 (en) 2012-05-29 2016-07-19 The University Of Vermont And State Agricultural College Methods of treating diseases associated with PPARγ
WO2014040008A1 (en) * 2012-09-10 2014-03-13 Angion Biomedica Corp. Relaxin-like peptides and uses thereof
KR102302634B1 (ko) 2013-09-13 2021-09-14 더 스크립스 리서치 인스티튜트 변형된 치료제 및 이의 조성물
EP3082797A4 (de) 2013-12-18 2017-12-13 The California Institute for Biomedical Research Modifizierte therapeutika, geheftete peptidlipidkonjugate und zusammensetzungen davon
MA41794A (fr) * 2015-03-18 2018-01-23 The California Institute For Biomedical Res Agents thérapeutiques modifiés et compositions associées
WO2017100540A2 (en) 2015-12-09 2017-06-15 The California Institute For Biomedical Research Relaxin immunoglobulin fusion proteins and methods of use
KR102670432B1 (ko) 2017-02-08 2024-05-28 브리스톨-마이어스 스큅 컴퍼니 약동학적 인핸서를 포함하는 변형된 렐락신 폴리펩티드 및 그의 용도
JP2024522196A (ja) 2021-06-09 2024-06-11 ザ スクリプス リサーチ インスティテュート 長時間作用型デュアルｇｉｐ／ｇｌｐ－１ペプチドコンジュゲートおよび使用方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL69469A (en) * 1982-08-12 1991-06-10 Florey Howard Inst Polypeptide having human h1-relaxin activity,double-stranded dna fragments coding therefor,vectors containing the dna fragments and methods for preparing the polypeptide,dna fragments and vectors
US4835251A (en) * 1986-06-23 1989-05-30 Genetech, Inc. Method of chain combination
US5478807A (en) * 1991-08-19 1995-12-26 Genentech, Inc. Use of relaxin in the treatment of bradycardia
US5166191A (en) * 1991-08-19 1992-11-24 Genentech, Inc. Use of relaxin in cardiovascular therapy

Also Published As

Publication number Publication date
ES2188763T3 (es) 2003-07-01
JP3830520B2 (ja) 2006-10-04
EP0831871A1 (de) 1998-04-01
WO1996040186A1 (en) 1996-12-19
DE69625354T2 (de) 2003-10-30
US5911997A (en) 1999-06-15
US6949506B2 (en) 2005-09-27
AU5869996A (en) 1996-12-30
EP0831871B1 (de) 2002-12-11
EP0831871A4 (de) 1999-03-03
CA2224080A1 (en) 1996-12-19
CA2224080C (en) 2010-07-27
US20030158376A1 (en) 2003-08-21
JPH11512072A (ja) 1999-10-19
AU709115B2 (en) 1999-08-19
ATE229340T1 (de) 2002-12-15

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