DE69527776D1 - Nachweis humaner papillomviren mit nukleinsäüre amplifikation die generelle primer verwendet - Google Patents
Nachweis humaner papillomviren mit nukleinsäüre amplifikation die generelle primer verwendetInfo
- Publication number
- DE69527776D1 DE69527776D1 DE69527776T DE69527776T DE69527776D1 DE 69527776 D1 DE69527776 D1 DE 69527776D1 DE 69527776 T DE69527776 T DE 69527776T DE 69527776 T DE69527776 T DE 69527776T DE 69527776 D1 DE69527776 D1 DE 69527776D1
- Authority
- DE
- Germany
- Prior art keywords
- mer
- seq
- complementary
- acid amplification
- detection
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000003321 amplification Effects 0.000 title abstract 2
- 238000003199 nucleic acid amplification method Methods 0.000 title abstract 2
- 238000001514 detection method Methods 0.000 title 1
- 150000007523 nucleic acids Chemical class 0.000 title 1
- 102000039446 nucleic acids Human genes 0.000 title 1
- 108020004707 nucleic acids Proteins 0.000 title 1
- 239000002773 nucleotide Substances 0.000 abstract 5
- 125000003729 nucleotide group Chemical group 0.000 abstract 5
- 230000000295 complement effect Effects 0.000 abstract 4
- 238000006467 substitution reaction Methods 0.000 abstract 3
- 239000012634 fragment Substances 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 abstract 1
- 108091034117 Oligonucleotide Proteins 0.000 abstract 1
- JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 210000004392 genitalia Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
- C12Q1/708—Specific hybridization probes for papilloma
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Virology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP94200432 | 1994-02-21 | ||
| EP94202739 | 1994-09-23 | ||
| PCT/NL1995/000066 WO1995022626A1 (en) | 1994-02-21 | 1995-02-20 | Human papilloma virus detection in a nucleic acid amplification process using general primers |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69527776D1 true DE69527776D1 (de) | 2002-09-19 |
| DE69527776T2 DE69527776T2 (de) | 2003-04-30 |
Family
ID=26136057
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69527776T Expired - Lifetime DE69527776T2 (de) | 1994-02-21 | 1995-02-20 | Nachweis humaner papillomviren mit nukleinsäüre amplifikation die generelle primer verwendet |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6352825B1 (de) |
| EP (1) | EP0746627B1 (de) |
| JP (1) | JP3659646B2 (de) |
| AT (1) | ATE222295T1 (de) |
| AU (1) | AU685233B2 (de) |
| CA (1) | CA2183758C (de) |
| DE (1) | DE69527776T2 (de) |
| DK (1) | DK0746627T3 (de) |
| ES (1) | ES2181765T3 (de) |
| WO (1) | WO1995022626A1 (de) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1007538A4 (de) * | 1996-04-15 | 2005-08-24 | Stc Unm | Sonden zum nachweis des menschlichen pappillomavirus |
| US6265154B1 (en) | 1996-10-25 | 2001-07-24 | Abbott Laboratories | Nucleic acid primers and probes for detecting oncogenic human papillomaviruses |
| FR2795074A1 (fr) * | 1999-05-21 | 2000-12-22 | Inst Nat Sante Rech Med | Polypeptides transporteurs d'acides amines, et en particulier du glutamate, et procedes de criblage de composes inhibiteurs ou activateurs de l'activite de transport |
| US20020025519A1 (en) | 1999-06-17 | 2002-02-28 | David J. Wright | Methods and oligonucleotides for detecting nucleic acid sequence variations |
| KR100382703B1 (ko) * | 2000-03-15 | 2003-05-09 | 주식회사 바이오메드랩 | 인유두종바이러스의 유전형 진단키트 및 상기 진단키트의제조방법 |
| GB0018050D0 (en) * | 2000-07-21 | 2000-09-13 | Norchip As | Detection of human papillomavirus mRNA |
| CN1186456C (zh) * | 2001-04-30 | 2005-01-26 | 曹卫 | 通用模板核酸检测方法和试剂盒 |
| US20060057561A1 (en) * | 2001-06-14 | 2006-03-16 | Hart Keith W | Virus detection method, primers therefor and screening kit |
| KR100437626B1 (ko) * | 2001-06-21 | 2004-06-26 | 주식회사 마이진 | 인간 유두종바이러스 유전자형 검사 방법과 이를 위한검사 키트 |
| GB0121166D0 (en) * | 2001-08-31 | 2001-10-24 | Norchip As | Detection of human papillomavirus L1 mRNA |
| KR100452163B1 (ko) * | 2001-09-14 | 2004-10-12 | 주식회사 바이오메드랩 | 인유두종 바이러스의 감염을 진단하기 위한 유전형 분석키트 |
| EP1302550A1 (de) * | 2001-10-10 | 2003-04-16 | King Car Food Industrial Co., Ltd. | Verfahren und Detektor für die Identifizierung von HPV Viren |
| GB0207242D0 (en) * | 2002-03-27 | 2002-05-08 | Norchip As | Universal detection of human papillomavirus mRNA |
| KR100452103B1 (ko) * | 2002-07-16 | 2004-10-08 | (주)차웰빙스 | 중합효소연쇄반응에 의한 종양원성 인유두종바이러스를검출하기 위한 프라이머와 종양원성 인유두종바이러스를검출하는 방법 |
| KR100491842B1 (ko) * | 2002-11-29 | 2005-05-27 | (주)차웰빙스 | 중합효소연쇄반응에 의한 다양한 유형의인유두종바이러스를 검출하기 위한 신규한 피씨알 공통프라이머와 그를 이용한 인유두종바이러스를 검출하는 방법 |
| US20040248085A1 (en) * | 2002-11-29 | 2004-12-09 | Sang-Wha Lee | General primers and process for detecting diverse genotypes of human papillomavirus by PCR |
| US20040248107A1 (en) * | 2003-06-09 | 2004-12-09 | Sokolova Irina A. | Detection of high grade dysplasia in cervical cells |
| AU2004275865B2 (en) | 2003-09-25 | 2008-09-25 | Third Wave Technologies, Inc. | Detection of HPV |
| WO2005100610A2 (en) * | 2004-04-15 | 2005-10-27 | University College Cardiff Consultants Limited | Virus detection method, primers therefor and screening kit |
| DE102004022350A1 (de) * | 2004-04-29 | 2005-11-17 | Genid Gmbh | Diagnose von Infektionserkrankungen |
| US7670774B2 (en) * | 2004-10-04 | 2010-03-02 | Goodgene Inc. | Probe of human papillomavirus and DNA chip comprising the same |
| EP1833985B1 (de) * | 2004-12-10 | 2014-08-27 | Genera Biosystems Limited | Nachweis von menschlichem papillomavirus unter verwendung von nukleinsäuresonden, mikrokügelchen und eines facs ( fluorescent-activated cell sorter)-geräts |
| GB0516145D0 (en) * | 2005-08-05 | 2005-09-14 | Genomica Sau | In vitro diagnostic kit for identification of human papillomavirus in clinical samples |
| US20070031826A1 (en) * | 2005-08-05 | 2007-02-08 | My Gene | Diagnostic kit for determining the genotype of a human papilloma virus and method of using thereof |
| US7910719B2 (en) * | 2005-12-08 | 2011-03-22 | Kabushiki Kaisha Toshiba | Method of detecting human papilloma virus by using nucleic acid amplification method and nucleic acid chain-immobilized carrier |
| US8080643B2 (en) * | 2006-09-05 | 2011-12-20 | Third Wave Technologies, Inc. | HPV primers |
| GB0702557D0 (en) * | 2007-02-09 | 2007-03-21 | Health Prot Agency | Detection of human papillomavirus |
| KR101451780B1 (ko) * | 2007-03-06 | 2014-10-16 | 주식회사 파나진 | 인유두종바이러스의 유전자형 검출을 위한 ρνα 프로브,키트 및 방법 |
| CN101730847B (zh) * | 2007-04-05 | 2015-03-18 | 分类生物系统有限公司 | 组合物及检测方法 |
| EP2034032A1 (de) | 2007-08-28 | 2009-03-11 | DKFZ Deutsches Krebsforschungszentrum, Stiftung des Öffentlichen Rechts | Zusammensetzung mit einer Oligonukleotidmischung für den besseren Nachweis von Genotypen des Humanpapillomavirus |
| KR101018407B1 (ko) | 2008-06-13 | 2011-03-02 | 엠앤디 (주) | 인유두종 바이러스 진단용 프로브 및 그 유전자형 확인방법 |
| US9090948B2 (en) | 2008-09-30 | 2015-07-28 | Abbott Molecular Inc. | Primers and probes for detecting human papillomavirus and human beta globin sequences in test samples |
| PL2358910T3 (pl) * | 2008-11-19 | 2018-05-30 | Diagcor Life Science Limited | Sekwencje nukleotydów, sposoby i zestawy do wykrywania HPV |
| EP2336369A1 (de) * | 2009-12-15 | 2011-06-22 | Deutsches Krebsforschungszentrum | Sonden zur Genotypisierung von risikoarmen HPV |
| US9376727B2 (en) | 2010-05-25 | 2016-06-28 | Qiagen Gaithersburg, Inc. | Fast results hybrid capture assay and associated strategically truncated probes |
| CA2823627C (en) | 2011-01-07 | 2021-05-11 | Qiagen Gaithersburg, Inc. | Materials and methods for genotyping and quantifying a high-risk human papillomavirus |
| CN102181550B (zh) * | 2011-04-18 | 2014-07-09 | 深圳康美生物科技股份有限公司 | 一种检测多种病原微生物的方法和试剂盒 |
| GB201511470D0 (en) * | 2015-06-30 | 2015-08-12 | Cellcall Kft | HPV detection method |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4886741A (en) * | 1987-12-09 | 1989-12-12 | Microprobe Corporation | Use of volume exclusion agents for the enhancement of in situ hybridization |
| US5182377A (en) * | 1988-09-09 | 1993-01-26 | Hoffmann-La Roche Inc. | Probes for detection of human papillomavirus |
| US5639871A (en) * | 1988-09-09 | 1997-06-17 | Roche Molecular Systems, Inc. | Detection of human papillomavirus by the polymerase chain reaction |
| NL9000134A (nl) * | 1990-01-19 | 1991-08-16 | Stichting Res Fonds Pathologie | Primers en werkwijze voor het detecteren van humaan papilloma virus genotypen m.b.v. pcr. |
| FR2660925B1 (fr) * | 1990-04-11 | 1994-07-01 | Inst Nat Sante Rech Med | Procede de fixation d'une sequence nucleotidique sur un support solide, applications et necessaires pour leur mise en óoeuvre. |
| JPH0458888A (ja) * | 1990-06-28 | 1992-02-25 | Shionogi & Co Ltd | ヒトパピローマウィルス遺伝子を検出するためのオリゴヌクレオチド及びそれを用いた検出方法 |
| CA2052413C (en) * | 1990-09-28 | 2004-07-13 | Jeffrey L. Joseph | Nucleotides sequences useful as type-specific probes, pcr primers and lcr probes for the amplifications and detection of human papilloma virus, and related kits and methods |
| IT1244462B (it) * | 1990-12-06 | 1994-07-15 | Sclavo Spa | Oligonucleotidi sintetici utili per la diagnosi di infezione da tipi diversi di virus del gruppo papilloma e loro utilizzazione |
-
1995
- 1995-02-20 JP JP52173295A patent/JP3659646B2/ja not_active Expired - Lifetime
- 1995-02-20 ES ES95908386T patent/ES2181765T3/es not_active Expired - Lifetime
- 1995-02-20 EP EP95908386A patent/EP0746627B1/de not_active Expired - Lifetime
- 1995-02-20 AU AU16722/95A patent/AU685233B2/en not_active Expired
- 1995-02-20 US US08/696,932 patent/US6352825B1/en not_active Expired - Lifetime
- 1995-02-20 AT AT95908386T patent/ATE222295T1/de active
- 1995-02-20 DE DE69527776T patent/DE69527776T2/de not_active Expired - Lifetime
- 1995-02-20 WO PCT/NL1995/000066 patent/WO1995022626A1/en not_active Ceased
- 1995-02-20 DK DK95908386T patent/DK0746627T3/da active
- 1995-02-20 CA CA002183758A patent/CA2183758C/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| AU1672295A (en) | 1995-09-04 |
| DK0746627T3 (da) | 2002-12-16 |
| EP0746627B1 (de) | 2002-08-14 |
| JPH09509062A (ja) | 1997-09-16 |
| WO1995022626A1 (en) | 1995-08-24 |
| ATE222295T1 (de) | 2002-08-15 |
| CA2183758A1 (en) | 1995-08-24 |
| EP0746627A1 (de) | 1996-12-11 |
| US6352825B1 (en) | 2002-03-05 |
| DE69527776T2 (de) | 2003-04-30 |
| JP3659646B2 (ja) | 2005-06-15 |
| CA2183758C (en) | 2007-09-25 |
| ES2181765T3 (es) | 2003-03-01 |
| AU685233B2 (en) | 1998-01-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8310 | Action for declaration of annulment | ||
| 8327 | Change in the person/name/address of the patent owner |
Owner name: QIAGEN GAITHERSBURG, INC., GAITHERSBURG, MD., US |
|
| 8328 | Change in the person/name/address of the agent |
Representative=s name: VOSSIUS & PARTNER, 81675 MUENCHEN |
|
| 8313 | Request for invalidation rejected/withdrawn |