[go: up one dir, main page]

DE69425074D1 - Durchflusszytometer - Google Patents

Durchflusszytometer

Info

Publication number
DE69425074D1
DE69425074D1 DE69425074T DE69425074T DE69425074D1 DE 69425074 D1 DE69425074 D1 DE 69425074D1 DE 69425074 T DE69425074 T DE 69425074T DE 69425074 T DE69425074 T DE 69425074T DE 69425074 D1 DE69425074 D1 DE 69425074D1
Authority
DE
Germany
Prior art keywords
flow cytometer
cytometer
flow
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69425074T
Other languages
English (en)
Other versions
DE69425074T2 (de
Inventor
E Auer
M Weber
D Starling
C Wood
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beckman Coulter Inc
Original Assignee
Coulter Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Coulter Corp filed Critical Coulter Corp
Application granted granted Critical
Publication of DE69425074D1 publication Critical patent/DE69425074D1/de
Publication of DE69425074T2 publication Critical patent/DE69425074T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J1/00—Photometry, e.g. photographic exposure meter
    • G01J1/42—Photometry, e.g. photographic exposure meter using electric radiation detectors
    • G01J1/44—Electric circuits
    • G01J2001/4406—Plural ranges in circuit, e.g. switchable ranges; Adjusting sensitivity selecting gain values
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
DE69425074T 1993-02-08 1994-01-25 Durchflusszytometer Expired - Fee Related DE69425074T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/014,701 US5367474A (en) 1993-02-08 1993-02-08 Flow cytometer
PCT/US1994/000904 WO1994018635A1 (en) 1993-02-08 1994-01-25 Flow cytometer

Publications (2)

Publication Number Publication Date
DE69425074D1 true DE69425074D1 (de) 2000-08-03
DE69425074T2 DE69425074T2 (de) 2001-03-08

Family

ID=21767158

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69425074T Expired - Fee Related DE69425074T2 (de) 1993-02-08 1994-01-25 Durchflusszytometer

Country Status (6)

Country Link
US (1) US5367474A (de)
EP (1) EP0752133B1 (de)
JP (1) JPH08507141A (de)
AU (1) AU6165594A (de)
DE (1) DE69425074T2 (de)
WO (1) WO1994018635A1 (de)

Families Citing this family (72)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6717096A (en) * 1995-08-01 1997-02-26 Mark J. Pasula Method for measuring the volume of liquid and/or solid in a suspension
US5736330A (en) * 1995-10-11 1998-04-07 Luminex Corporation Method and compositions for flow cytometric determination of DNA sequences
CA2227895C (en) 1995-10-11 2012-07-17 Luminex Corporation Multiplexed analysis of clinical specimens apparatus and methods
US5981180A (en) * 1995-10-11 1999-11-09 Luminex Corporation Multiplexed analysis of clinical specimens apparatus and methods
US6449562B1 (en) 1996-10-10 2002-09-10 Luminex Corporation Multiplexed analysis of clinical specimens apparatus and method
AU752985B2 (en) 1997-01-31 2002-10-03 Xy, Llc. Optical apparatus
US6071689A (en) 1997-12-31 2000-06-06 Xy, Inc. System for improving yield of sexed embryos in mammals
US6149867A (en) 1997-12-31 2000-11-21 Xy, Inc. Sheath fluids and collection systems for sex-specific cytometer sorting of sperm
WO1999036564A1 (en) * 1998-01-16 1999-07-22 Luminex Corporation Multiplexed analysis of clinical specimens apparatus and methods
AU4184099A (en) * 1998-05-14 1999-11-29 Luminex Corporation Zero dead time architecture and method for flow cytometer
WO2000006994A1 (fr) * 1998-07-27 2000-02-10 Kowa Company, Ltd. Technique de comptage et compteur de grains de pollen
JP2002521043A (ja) 1998-07-30 2002-07-16 エックスワイ，インコーポレイテッド 非外科的人工授精のためのウマシステム
US7024316B1 (en) 1999-10-21 2006-04-04 Dakocytomation Colorado, Inc. Transiently dynamic flow cytometer analysis system
WO2001028700A1 (en) * 1999-10-21 2001-04-26 Cytomation, Inc. Transiently dynamic flow cytometer analysis system
US7208265B1 (en) 1999-11-24 2007-04-24 Xy, Inc. Method of cryopreserving selected sperm cells
US6421121B1 (en) * 2000-02-10 2002-07-16 Micro Imaging Technology Method and apparatus for rapid particle identification utilizing scattered light histograms
US6587203B2 (en) 2000-02-17 2003-07-01 Cornell Research Foundation, Inc. Sort stream stabilizer for flow cytometer
EP2258174A3 (de) 2000-05-09 2012-06-13 Xy, Llc Hochreines X-Chromosom-Lager und Y-Chromosom-Lagerpopulationen von Spermatozoiden
US7630063B2 (en) * 2000-08-02 2009-12-08 Honeywell International Inc. Miniaturized cytometer for detecting multiple species in a sample
US7277166B2 (en) * 2000-08-02 2007-10-02 Honeywell International Inc. Cytometer analysis cartridge optical configuration
WO2002043486A1 (en) 2000-11-29 2002-06-06 Xy, Inc. System for in-vitro fertilization with spermatozoa separated into x-chromosome and y-chromosome bearing populations
US7713687B2 (en) 2000-11-29 2010-05-11 Xy, Inc. System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations
JP2002311027A (ja) * 2001-04-09 2002-10-23 Hitachi Software Eng Co Ltd ビーズ、ビーズ製造方法、フローサイトメータ及びプログラム
EP1281951A1 (de) * 2001-08-03 2003-02-05 PointSource Technologies, LLC Verfahren und Vorrichtung zur Identifizierung von Teilchen in einem Fluid
AU784061B2 (en) * 2002-04-23 2006-01-19 Micro Imaging Technology Method and apparatus for rapid particle identification utilizing scattered light histograms
US8486618B2 (en) 2002-08-01 2013-07-16 Xy, Llc Heterogeneous inseminate system
EP2284256A3 (de) 2002-08-01 2012-08-29 Xy, Llc Niederdruck-Spermatrennsystem
JP2005535346A (ja) 2002-08-15 2005-11-24 エックスワイ，インコーポレイテッド 高分解能フローサイトメーター
US7169548B2 (en) 2002-09-13 2007-01-30 Xy, Inc. Sperm cell processing and preservation systems
US6847904B2 (en) * 2003-02-25 2005-01-25 Microchip Technology Incorporated Multi-channel programmable gain amplifier controlled with a serial interface
US7505855B2 (en) * 2003-02-25 2009-03-17 Microchip Technology Incorporated Multi-channel amplifier having programmable operational characteristics controlled with a serial interface
CA2518882C (en) 2003-03-28 2017-05-09 Monsanto Technology Llc Apparatus, methods and processes for sorting particles and for providing sex-sorted animal sperm
ES2541121T3 (es) 2003-05-15 2015-07-16 Xy, Llc Clasificación eficiente de células haploides por sistemas de citometría de flujo
US7069191B1 (en) * 2003-08-06 2006-06-27 Luminex Corporation Methods for reducing the susceptibility of a peak search to signal noise
CN101187621B (zh) * 2004-01-14 2012-02-15 卢米尼克斯股份有限公司 用于动态范围扩展的方法和系统
US7440101B2 (en) * 2004-01-23 2008-10-21 Beckman Coulter, Inc. System and method for multiple laser triggering
EP2801363B1 (de) 2004-03-29 2018-02-21 Inguran, LLC Verfahren zur lagerung von sortierten spermatozoen
US7477363B2 (en) * 2004-04-08 2009-01-13 Nihon Kohden Corporation Flow cytometer
AU2005266930B2 (en) 2004-07-22 2010-09-16 Inguran, Llc Process for enriching a population of sperm cells
DK2884258T3 (da) 2004-07-27 2017-01-02 Beckman Coulter Inc Forbedring af flowcytometrisk diskrimination med computerimplementeret geometrisk transformation
US7612871B2 (en) * 2004-09-01 2009-11-03 Honeywell International Inc Frequency-multiplexed detection of multiple wavelength light for flow cytometry
US20060219873A1 (en) * 2005-04-01 2006-10-05 Martin Steven M Detection system for a flow cytometer
US7618770B2 (en) 2005-07-29 2009-11-17 Xy, Inc. Methods and apparatus for reducing protein content in sperm cell extenders
US7996188B2 (en) * 2005-08-22 2011-08-09 Accuri Cytometers, Inc. User interface for a flow cytometer system
US8017402B2 (en) 2006-03-08 2011-09-13 Accuri Cytometers, Inc. Fluidic system for a flow cytometer
US8303894B2 (en) 2005-10-13 2012-11-06 Accuri Cytometers, Inc. Detection and fluidic system of a flow cytometer
US20070127863A1 (en) * 2005-12-07 2007-06-07 Accuri Instruments Inc. System and method for guiding light from an interrogation zone to a detector system
US8149402B2 (en) * 2006-02-22 2012-04-03 Accuri Cytometers, Inc. Optical system for a flow cytometer
US7780916B2 (en) * 2006-03-08 2010-08-24 Accuri Cytometers, Inc. Flow cytometer system with unclogging feature
US8283177B2 (en) * 2006-03-08 2012-10-09 Accuri Cytometers, Inc. Fluidic system with washing capabilities for a flow cytometer
MEP11108A (en) 2006-03-10 2010-10-10 Saryna Biotechnologies Llc High speed sample supply device
US20070224684A1 (en) * 2006-03-22 2007-09-27 Olson David C Transportable flow cytometer
US8077310B2 (en) * 2006-08-30 2011-12-13 Accuri Cytometers, Inc. System and method of capturing multiple source excitations from a single location on a flow channel
US8715573B2 (en) * 2006-10-13 2014-05-06 Accuri Cytometers, Inc. Fluidic system for a flow cytometer with temporal processing
WO2008058217A2 (en) 2006-11-07 2008-05-15 Accuri Instruments Inc. Flow cell for a flow cytometer system
US7739060B2 (en) * 2006-12-22 2010-06-15 Accuri Cytometers, Inc. Detection system and user interface for a flow cytometer system
JP5385161B2 (ja) * 2007-03-23 2014-01-08 ベックマン コールター， インコーポレイテッド フローサイトメトリに関する用途についてのマルチゲインアダプティブリニア処理およびゲート制御されたデジタルシステム
US8432541B2 (en) * 2007-12-17 2013-04-30 Accuri Cytometers, Inc. Optical system for a flow cytometer with an interrogation zone
US7843561B2 (en) * 2007-12-17 2010-11-30 Accuri Cytometers, Inc. Optical system for a flow cytometer with an interrogation zone
US8507279B2 (en) * 2009-06-02 2013-08-13 Accuri Cytometers, Inc. System and method of verification of a prepared sample for a flow cytometer
US8004674B2 (en) * 2009-06-02 2011-08-23 Accuri Cytometers, Inc. Data collection system and method for a flow cytometer
WO2011106402A1 (en) * 2010-02-23 2011-09-01 Accuri Cytometers, Inc. Method and system for detecting fluorochromes in a flow cytometer
US9551600B2 (en) 2010-06-14 2017-01-24 Accuri Cytometers, Inc. System and method for creating a flow cytometer network
JP5671623B2 (ja) * 2010-10-25 2015-02-18 アキュリ サイトメーターズ, インコーポレイテッドAccuri Cytometers, Inc. フローサイトメータのデータセットを収集するシステム及びユーザインターフェース
JP5831059B2 (ja) * 2011-09-07 2015-12-09 ソニー株式会社 光学的測定装置、フローサイトメーター及び光学的測定方法
JP5772425B2 (ja) 2011-09-13 2015-09-02 ソニー株式会社 微小粒子測定装置
WO2014082096A1 (en) 2012-11-26 2014-05-30 The Trustees Of Columbia University In The City Of New York Method for culture of human and mouse prostate organoids and uses thereof
GB201506335D0 (en) * 2015-04-14 2015-05-27 Alphasense Ltd Optical particle counter
JP6531528B2 (ja) * 2015-07-15 2019-06-19 富士電機株式会社 粒子検出装置
WO2017106439A1 (en) * 2015-12-18 2017-06-22 Abbott Laboratories Particle detection methods and systems for practicing same
US11181464B2 (en) * 2018-06-19 2021-11-23 Becton, Dickinson And Company Variable multiplexing switches for detector arrays, systems and methods of use thereof
EP4130711A4 (de) * 2020-03-24 2023-09-27 Sony Group Corporation Informationsverarbeitungsvorrichtung, informationsverarbeitungsverfahren und informationsverarbeitungsprogramm

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3380584A (en) * 1965-06-04 1968-04-30 Atomic Energy Commission Usa Particle separator
US3657537A (en) * 1970-04-03 1972-04-18 Bausch & Lomb Computerized slit-scan cyto-fluorometer for automated cell recognition
DE2201507C2 (de) * 1972-01-13 1974-01-24 Theo Dipl.-Ing. Dr. 8000 Muenchen Pilhofer Vorrichtung zur Bestimmung der Größe der dispersen Elemente eines fluiden, nicht mischbaren Zweistoffsystems
US3761889A (en) * 1972-02-24 1973-09-25 Foxboro Co Computer directed process control system with analog input multiplexer
US3923397A (en) * 1974-05-29 1975-12-02 Dolive Stephen E Hematocrit measuring method
NL180704C (nl) * 1976-06-14 Coulter Electronics Inrichting voor gelijktijdige optische meting van kenmerken van zich in een suspensie bevindende deeltjes.
US4348107A (en) * 1980-07-18 1982-09-07 Coulter Electronics, Inc. Orifice inside optical element
US4667830A (en) * 1981-06-15 1987-05-26 The Board Of Trustees Of The Leland Stanford Junior University Method and means for sorting individual particles into containers for culturing, cloning, analysis, or the like
US4707454A (en) * 1981-08-10 1987-11-17 Bio-Diagnostics, Inc. Fluorescent chlorophyll labeled assay reagents
JPS59174742A (ja) * 1983-03-25 1984-10-03 Agency Of Ind Science & Technol 微小粒子を区分又は選別する方法及びその装置
US4987539A (en) * 1987-08-05 1991-01-22 Stanford University Apparatus and method for multidimensional characterization of objects in real time
CA2010866C (en) * 1989-02-28 1995-02-07 Shigeo Amemiya Polling communication system

Also Published As

Publication number Publication date
US5367474A (en) 1994-11-22
EP0752133A4 (de) 1997-12-10
EP0752133B1 (de) 2000-06-28
JPH08507141A (ja) 1996-07-30
EP0752133A1 (de) 1997-01-08
AU6165594A (en) 1994-08-29
WO1994018635A1 (en) 1994-08-18
DE69425074T2 (de) 2001-03-08

Similar Documents

Publication Publication Date Title
DE69425074D1 (de) Durchflusszytometer
DE69533469D1 (de) Durchflusszytometer
DK0737307T3 (da) Væskegennemstrømningscytometer
NO307714B1 (no) Strømningspåvirker
DE69308366D1 (de) Strömungsventil
KR950702286A (ko) 마이크로밸브(Microvalve)
NO943999L (no) 1-aminoetylindolderivater
NO952732D0 (no) Gjennomströmningsmåler
DE69316016D1 (de) Durchflussmesser
DE69433403D1 (de) Hocheffiziente fluoreszenzflusszelle
NO955149D0 (no) Myk-gelede gelatininnkapslede partikler
NO944426D0 (no) Målekammer for strömnings-cytometer
FI952067A7 (fi) Nestekytkennät
FI950850L (fi) Virtausmittari
NO942978L (no) Funksjonelt fluid
DE69310370D1 (de) Strömungsmesser
FI953100L (fi) Venttiili
DE69303658D1 (de) Sortierer
DE59404377D1 (de) Durchflussvolumenzähler
FI945872L (fi) Kanisteri
DK142693A (da) Flowmåler
KR950006916U (ko) 유체
ATA95292A (de) Strömungssicherung
SE9403751D0 (sv) flyt 1
ITMI910817U1 (it) Flussostato

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: COULTER INTERNATIONAL CORP., MIAMI, FLA., US

8339 Ceased/non-payment of the annual fee