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DE69422604D1 - Vorrichtung und Verfahren, die Bioaffinitätsassay und elektrophoretische Auftrennung kombinieren - Google Patents

Vorrichtung und Verfahren, die Bioaffinitätsassay und elektrophoretische Auftrennung kombinieren

Info

Publication number
DE69422604D1
DE69422604D1 DE69422604T DE69422604T DE69422604D1 DE 69422604 D1 DE69422604 D1 DE 69422604D1 DE 69422604 T DE69422604 T DE 69422604T DE 69422604 T DE69422604 T DE 69422604T DE 69422604 D1 DE69422604 D1 DE 69422604D1
Authority
DE
Germany
Prior art keywords
combine
electrophoretic separation
bioaffinity assay
bioaffinity
assay
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69422604T
Other languages
English (en)
Other versions
DE69422604T2 (de
Inventor
Dr Ensing
Dr Oroszlan
Dr Paulus
Carlo S Dr Effenhauser
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zeptosens AG
Original Assignee
Zeptosens AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zeptosens AG filed Critical Zeptosens AG
Application granted granted Critical
Publication of DE69422604D1 publication Critical patent/DE69422604D1/de
Publication of DE69422604T2 publication Critical patent/DE69422604T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/558—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
    • G01N33/561—Immunoelectrophoresis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2474/00—Immunochemical assays or immunoassays characterised by detection mode or means of detection
    • G01N2474/20—Immunohistochemistry assay
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/961—Chemistry: molecular biology and microbiology including a step of forming, releasing, or exposing the antigen or forming the hapten-immunogenic carrier complex or the antigen per se
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures
    • Y10S436/81—Tube, bottle, or dipstick

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Electrochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE69422604T 1994-03-08 1994-03-08 Vorrichtung und Verfahren, die Bioaffinitätsassay und elektrophoretische Auftrennung kombinieren Expired - Fee Related DE69422604T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP94810146A EP0671626B1 (de) 1994-03-08 1994-03-08 Vorrichtung und Verfahren, die Bioaffinitätsassay und elektrophoretische Auftrennung kombinieren

Publications (2)

Publication Number Publication Date
DE69422604D1 true DE69422604D1 (de) 2000-02-17
DE69422604T2 DE69422604T2 (de) 2000-06-08

Family

ID=8218222

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69422604T Expired - Fee Related DE69422604T2 (de) 1994-03-08 1994-03-08 Vorrichtung und Verfahren, die Bioaffinitätsassay und elektrophoretische Auftrennung kombinieren

Country Status (5)

Country Link
US (1) US5741639A (de)
EP (1) EP0671626B1 (de)
JP (1) JPH07311198A (de)
CA (1) CA2143999C (de)
DE (1) DE69422604T2 (de)

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US6020209A (en) * 1997-04-28 2000-02-01 The United States Of America As Represented By The Secretary Of The Navy Microcapillary-based flow-through immunosensor and displacement immunoassay using the same
JP4276301B2 (ja) * 1997-05-16 2009-06-10 エグザクト サイエンシーズ コーポレイション 固定化プローブを用いる、分子の電気泳動分析
US6368871B1 (en) * 1997-08-13 2002-04-09 Cepheid Non-planar microstructures for manipulation of fluid samples
US6255051B1 (en) 1997-11-06 2001-07-03 Mosaic Technologies Inc. Multiple sequential polynucleotide displacement reactions for signal amplification and processing
WO1999026724A2 (en) 1997-11-25 1999-06-03 Mosaic Technologies Devices and methods for detecting target molecules in biological samples
ES2309022T3 (es) 1997-12-24 2008-12-16 Cepheid Dispositivo y procedimiento para lisis.
JP2002518025A (ja) 1998-06-18 2002-06-25 モザイク テクノロジーズ 変性勾配アフィニティー電気泳動及びその使用方法
EP1088105A4 (de) * 1998-06-19 2003-06-25 Exact Sciences Corp Detektion nicht-viraler organismen mittels srp-rna
EP2273270A1 (de) 1998-08-28 2011-01-12 febit holding GmbH Verfahren und Vorrichtung zur Herstellung und/oder Analyse von biochemischen Reaktionsträgern
US6238927B1 (en) 1998-10-05 2001-05-29 Mosaic Technologies, Incorporated Reverse displacement assay for detection of nucleic acid sequences
US6887693B2 (en) 1998-12-24 2005-05-03 Cepheid Device and method for lysing cells, spores, or microorganisms
US6431476B1 (en) 1999-12-21 2002-08-13 Cepheid Apparatus and method for rapid ultrasonic disruption of cells or viruses
US7914994B2 (en) * 1998-12-24 2011-03-29 Cepheid Method for separating an analyte from a sample
ES2221841T3 (es) * 1999-02-26 2005-01-16 Exact Sciences Corporation Dispositivos de purificacion bioquimica con sondas de captacion inmovilizadas y su utilizacion.
JP3957118B2 (ja) * 1999-05-18 2007-08-15 富士フイルム株式会社 試験片およびこの試験片からの画像情報読取装置
JP4022069B2 (ja) 1999-05-28 2007-12-12 シーフィード 細胞破壊装置および方法
US9073053B2 (en) 1999-05-28 2015-07-07 Cepheid Apparatus and method for cell disruption
US8815521B2 (en) 2000-05-30 2014-08-26 Cepheid Apparatus and method for cell disruption
US20040200909A1 (en) * 1999-05-28 2004-10-14 Cepheid Apparatus and method for cell disruption
US6294392B1 (en) 1999-07-21 2001-09-25 The Regents Of The University Of California Spatially-encoded analyte detection
US7214477B1 (en) 1999-07-26 2007-05-08 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Layered device with capture regions for cellular analysis
ES2269171T3 (es) 1999-07-26 2007-04-01 The Government Of The United States Of America, As Represented By The Secretary, Department Of Heal Dispositivo en capas con regiones de captura para analisis celular.
US6969615B2 (en) * 1999-07-26 2005-11-29 20/20 Genesystems, Inc. Methods, devices, arrays and kits for detecting and analyzing biomolecules
US7838222B2 (en) * 1999-07-26 2010-11-23 United States of America/ NIH Methods, devices and kits for multiplex blotting of biological samples from multi-well plates
US6423536B1 (en) * 1999-08-02 2002-07-23 Molecular Dynamics, Inc. Low volume chemical and biochemical reaction system
US6406604B1 (en) * 1999-11-08 2002-06-18 Norberto A. Guzman Multi-dimensional electrophoresis apparatus
US7329388B2 (en) * 1999-11-08 2008-02-12 Princeton Biochemicals, Inc. Electrophoresis apparatus having staggered passage configuration
US6676815B1 (en) * 1999-12-30 2004-01-13 Roche Diagnostics Corporation Cell for electrochemical analysis of a sample
AU2001242928A1 (en) * 2000-03-16 2001-09-24 Biacore Ab Method for capturing analytes eluted from surface-bound ligands
DE10051396A1 (de) 2000-10-17 2002-04-18 Febit Ferrarius Biotech Gmbh Verfahren und Vorrichtung zur integrierten Synthese und Analytbestimmung an einem Träger
US7691645B2 (en) * 2001-01-09 2010-04-06 Agilent Technologies, Inc. Immunosubtraction method
SE526185C2 (sv) 2001-11-07 2005-07-19 Prolight Diagnostics Ab Metod och anordning för immunanalys
US20060147926A1 (en) * 2002-11-25 2006-07-06 Emmert-Buck Michael R Method and apparatus for performing multiple simultaneous manipulations of biomolecules in a two-dimensional array
EP1706735B1 (de) * 2003-11-07 2017-01-04 Princeton Biochemicals, Inc. Mehrdimensionale elektrophoresevorrichtung
US8007724B2 (en) * 2003-11-07 2011-08-30 Princeton Biochemicals, Inc. Electrophoresis apparatus having at least one auxiliary buffer passage
FR2862134B1 (fr) * 2003-11-12 2007-07-27 Sebia Sa Analyse et typage de proteines monoclonales par electrophorese capillaire et immunodeplacement
US20070148759A1 (en) * 2003-12-26 2007-06-28 Yoshinori Amano Biological sample discrimination device, biological sample discriminating method, and biological sample discriminating plate
WO2005095967A1 (en) * 2004-03-23 2005-10-13 Quidel Corporation Hybrid phase lateral flow assay
US7378054B2 (en) * 2004-04-16 2008-05-27 Savvipharm Inc Specimen collecting, processing and analytical assembly
EP3527976A1 (de) * 2004-07-19 2019-08-21 ProteinSimple Verfahren und vorrichtungen zur analytdetektion
US7211184B2 (en) * 2004-08-04 2007-05-01 Ast Management Inc. Capillary electrophoresis devices
US20060160210A1 (en) * 2004-11-26 2006-07-20 Matsushita Electric Industrial Co., Ltd. Biological sample analysis plate
US20080075632A1 (en) * 2004-12-08 2008-03-27 Kazuyoshi Mori Biological Sample Analysis Plate
CN101317086B (zh) * 2005-10-04 2013-08-14 海德威技术公司 分析物的微观流体检测
JP4749867B2 (ja) 2006-01-13 2011-08-17 パナソニック株式会社 電気泳動装置
US9528939B2 (en) 2006-03-10 2016-12-27 Indx Lifecare, Inc. Waveguide-based optical scanning systems
US9976192B2 (en) 2006-03-10 2018-05-22 Ldip, Llc Waveguide-based detection system with scanning light source
US9423397B2 (en) 2006-03-10 2016-08-23 Indx Lifecare, Inc. Waveguide-based detection system with scanning light source
WO2009009408A2 (en) * 2007-07-06 2009-01-15 Applied Biosystems Inc. Devices and methods for the detection of analytes
DE102010011560B4 (de) * 2010-03-16 2021-09-16 Gilupi Gmbh Biodetektor
US9696299B2 (en) 2010-11-01 2017-07-04 Norberto Guzman Integrated modular unit including an analyte concentrator microreactor device connected to a cartridge-cassette
US8865075B2 (en) 2010-11-01 2014-10-21 Princeton Biochemicals, Inc. Multi-task immunoaffinity device secured to a peripheral box and integrated to a capillary electrophoresis apparatus
WO2015072265A1 (ja) * 2013-11-12 2015-05-21 公立大学法人福島県立医科大学 分離分析用キャピラリーデバイス、分離分析用マイクロ流体チップ、タンパク質又はペプチド分析方法、電気泳動装置、及び分離分析用マイクロ流体チップ電気泳動装置
US10018566B2 (en) 2014-02-28 2018-07-10 Ldip, Llc Partially encapsulated waveguide based sensing chips, systems and methods of use
WO2016138427A1 (en) 2015-02-27 2016-09-01 Indx Lifecare, Inc. Waveguide-based detection system with scanning light source
US11198118B2 (en) 2017-03-29 2021-12-14 Princeton Biochemicals, Inc. Integrated modular unit containing one or more analyte concentrator-microreactor devices to be coupled to a cartridge-cassette and methods of operation
CN110579603B (zh) * 2019-08-27 2022-08-30 武汉纺织大学 一种病毒检测传感器、一种检测病毒浓度的装置和方法
US20210263025A1 (en) * 2020-02-20 2021-08-26 FemtoDx Micro-separation for multiplexing

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NZ199286A (en) * 1980-12-22 1986-05-09 Commw Serum Lab Commission A method of detecting antibodies or an antigenic or haptenic substance in a sample
FR2498331A1 (fr) * 1981-01-20 1982-07-23 Kadouche Jean Recipient reactif pour analyse notamment immunologique
US4865707A (en) * 1986-10-21 1989-09-12 Northeastern University Capillary gel electrophoresis columns
US5013669A (en) * 1988-06-01 1991-05-07 Smithkline Diagnostics, Inc. Mass producible biologically active solid phase devices
US5135627A (en) * 1990-10-15 1992-08-04 Soane Technologies, Inc. Mosaic microcolumns, slabs, and separation media for electrophoresis and chromatography
JPH05172815A (ja) * 1991-12-26 1993-07-13 Hitachi Ltd 免疫分析方法及びその分析装置

Also Published As

Publication number Publication date
EP0671626A1 (de) 1995-09-13
EP0671626B1 (de) 2000-01-12
US5741639A (en) 1998-04-21
DE69422604T2 (de) 2000-06-08
CA2143999A1 (en) 1995-09-09
JPH07311198A (ja) 1995-11-28
CA2143999C (en) 2005-10-18

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee