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DE68905886D1 - Calcitoninzusammensetzung zur intranasalen verabreichung. - Google Patents

Calcitoninzusammensetzung zur intranasalen verabreichung.

Info

Publication number
DE68905886D1
DE68905886D1 DE8989116685T DE68905886T DE68905886D1 DE 68905886 D1 DE68905886 D1 DE 68905886D1 DE 8989116685 T DE8989116685 T DE 8989116685T DE 68905886 T DE68905886 T DE 68905886T DE 68905886 D1 DE68905886 D1 DE 68905886D1
Authority
DE
Germany
Prior art keywords
calciton
composition
intranasal administration
intranasal
administration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8989116685T
Other languages
English (en)
Other versions
DE68905886T2 (de
Inventor
Klunk, Jr
Peter E Grebow
Herschel H Li
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhone Poulenc Rorer International Holdings Inc
Original Assignee
Rhone Poulenc Rorer International Holdings Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer International Holdings Inc filed Critical Rhone Poulenc Rorer International Holdings Inc
Application granted granted Critical
Publication of DE68905886D1 publication Critical patent/DE68905886D1/de
Publication of DE68905886T2 publication Critical patent/DE68905886T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183Amino acids, e.g. glycine, EDTA or aspartame
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/23Calcitonins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/10Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
    • A61P5/12Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH for decreasing, blocking or antagonising the activity of the posterior pituitary hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Otolaryngology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
DE8989116685T 1988-09-08 1989-09-08 Calcitoninzusammensetzung zur intranasalen verabreichung. Expired - Fee Related DE68905886T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/242,000 US5026825A (en) 1988-09-08 1988-09-08 Intranasal calcitonin formulations

Publications (2)

Publication Number Publication Date
DE68905886D1 true DE68905886D1 (de) 1993-05-13
DE68905886T2 DE68905886T2 (de) 1993-07-15

Family

ID=22913078

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8989116685T Expired - Fee Related DE68905886T2 (de) 1988-09-08 1989-09-08 Calcitoninzusammensetzung zur intranasalen verabreichung.

Country Status (5)

Country Link
US (1) US5026825A (de)
EP (1) EP0358234B1 (de)
JP (1) JPH02115130A (de)
DE (1) DE68905886T2 (de)
ES (1) ES2061851T3 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5446070A (en) * 1991-02-27 1995-08-29 Nover Pharmaceuticals, Inc. Compositions and methods for topical administration of pharmaceutically active agents
WO1991013601A1 (en) * 1990-03-15 1991-09-19 Rhône-Poulenc Rorer International (Holdings) Inc. Calcitonin suppository formulations
JPH078806B2 (ja) * 1990-08-16 1995-02-01 旭化成工業株式会社 カルシトニン類含有経鼻投与用乳剤
EP0489217A1 (de) * 1990-12-05 1992-06-10 Dr. A. Tosi Farmaceutici S.R.L. Calcitoninzusammensetzungen zur intranasalen Verabreichung
JP3179538B2 (ja) * 1990-12-11 2001-06-25 ノバルティス アクチエンゲゼルシャフト 安定なヒトカルシトニンの水性溶液
GB9102579D0 (en) * 1991-01-24 1991-03-27 Glaxo Group Ltd Compositions
US5688761A (en) * 1991-04-19 1997-11-18 Lds Technologies, Inc. Convertible microemulsion formulations
CA2108266C (en) * 1991-04-19 2003-06-03 Albert J. Owen Convertible microemulsion formulations
US5571788A (en) * 1991-12-09 1996-11-05 Ciba-Geigy Corporation Stable calcitonin pharmaceutical compositions
EP0736041B1 (de) * 1993-11-17 2006-02-08 Athena Neurosciences, Inc. Transparente flüssigkeit zur verabreichung von verkapselten medikamenten
EP0726075A1 (de) * 1995-02-08 1996-08-14 Therapicon Srl Nicht-inorganische pharmazeutische salzige Lösungen zur endonasale Verabreichung
US5698672A (en) * 1995-04-04 1997-12-16 Zymogenetics, Inc. Synthetic calcitonin mimetics
DE19744811C2 (de) * 1997-10-02 1999-11-18 Medac Klinische Spezialpraep Verwendung von delta-Aminolävulinsäure zur Herstellung eines topischen Arzneimittels zur integralen Diagnose und/oder Therapie von Tumoren in Hohlorganen
US6187332B1 (en) * 1999-06-14 2001-02-13 Wisconsin Alumni Research Foundation Acidic buffered nasal spray
US6398774B1 (en) * 1999-09-29 2002-06-04 Heska Corporation Intranasal delivery system
DE10003620A1 (de) * 2000-01-28 2001-08-02 Asat Ag Applied Science & Tech 5-Aminolävulinsäure-Formulierung in nichtwässrigen Lösungsmitteln
AU783952B2 (en) 2000-02-04 2006-01-05 Unigene Laboratories, Inc. Nasal calcitonin formulations
US7812120B2 (en) 2003-03-21 2010-10-12 Par Pharmaceutical, Inc. Nasal calcitonin formulations containing chlorobutanol
US20050175679A1 (en) * 2004-02-10 2005-08-11 Michael Moshman Controlled release formulations
US7989420B2 (en) 2006-03-28 2011-08-02 New York Medical College Smooth muscle relaxation
MX338110B (es) * 2009-09-25 2016-04-01 Reddys Lab Ltd Dr Formulaciones que comprenden compuestos de triptano.
US11337962B2 (en) 2009-09-25 2022-05-24 Upsher-Smith Laboratories, Llc Formulations comprising triptan compounds
GB202201708D0 (en) * 2022-02-10 2022-03-30 Intract Pharma Ltd Compositions for oral delivery of biotherapeutics

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU65921A1 (de) * 1972-08-18 1974-02-21
US4568665A (en) * 1982-06-25 1986-02-04 Mitchell David C Protein compounds
GB8514090D0 (en) * 1985-06-04 1985-07-10 Sandoz Ltd Organic compounds
US4692433A (en) * 1983-10-12 1987-09-08 The Regents Of The University Of California Method and composition for regulating serum calcium levels of mammals
JPS6160620A (ja) * 1984-09-03 1986-03-28 Teijin Ltd ピログルタミン酸エステル類を含有する医薬品組成物
JPS61267528A (ja) * 1984-11-26 1986-11-27 Yamanouchi Pharmaceut Co Ltd 吸収促進剤を含有するカルシトニン経鼻剤
HUT44794A (en) * 1985-12-04 1988-04-28 Sandoz Ag Process for production of calcitonine-derivatives and medical preparatives containing such compounds
US4746728A (en) * 1986-05-05 1988-05-24 Armour Pharmaceutical Company 8-glycine, des-19-leucine-calcitonin
MY102411A (en) * 1986-12-23 1992-06-17 Ciba Geigy Ag Nasal solutions
IL91856A0 (en) * 1988-10-11 1990-06-10 Schiapparelli Salute Spa Pharmaceutical compositions comprising calcitonin for intranasal administration and a spray unit for the administration of the same

Also Published As

Publication number Publication date
JPH02115130A (ja) 1990-04-27
US5026825A (en) 1991-06-25
DE68905886T2 (de) 1993-07-15
EP0358234A3 (en) 1990-10-31
EP0358234B1 (de) 1993-04-07
ES2061851T3 (es) 1994-12-16
EP0358234A2 (de) 1990-03-14

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee