DE60331677D1 - Kit zur untersuchung von menschlichem niedermolekulargewicht cd14 und antikörper - Google Patents
Kit zur untersuchung von menschlichem niedermolekulargewicht cd14 und antikörperInfo
- Publication number
- DE60331677D1 DE60331677D1 DE60331677T DE60331677T DE60331677D1 DE 60331677 D1 DE60331677 D1 DE 60331677D1 DE 60331677 T DE60331677 T DE 60331677T DE 60331677 T DE60331677 T DE 60331677T DE 60331677 D1 DE60331677 D1 DE 60331677D1
- Authority
- DE
- Germany
- Prior art keywords
- human low
- kit
- antibodies
- study
- peptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 101000946889 Homo sapiens Monocyte differentiation antigen CD14 Proteins 0.000 title abstract 4
- 102100035877 Monocyte differentiation antigen CD14 Human genes 0.000 title abstract 4
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 3
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 2
- 206010040047 Sepsis Diseases 0.000 abstract 1
- 125000000539 amino acid group Chemical group 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 238000003556 assay Methods 0.000 abstract 1
- 238000003149 assay kit Methods 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000035945 sensitivity Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70596—Molecules with a "CD"-designation not provided for elsewhere
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/26—Infectious diseases, e.g. generalised sepsis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Cell Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2002328866 | 2002-11-12 | ||
| JP2003330775 | 2003-09-22 | ||
| PCT/JP2003/014389 WO2004044005A1 (ja) | 2002-11-12 | 2003-11-12 | ヒト低分子量ｃｄ１４測定キットおよび抗体 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60331677D1 true DE60331677D1 (de) | 2010-04-22 |
Family
ID=32314082
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60331677T Expired - Lifetime DE60331677D1 (de) | 2002-11-12 | 2003-11-12 | Kit zur untersuchung von menschlichem niedermolekulargewicht cd14 und antikörper |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US7465547B2 (de) |
| EP (1) | EP1571160B1 (de) |
| JP (1) | JP4081489B2 (de) |
| CN (1) | CN100558746C (de) |
| AT (1) | ATE460430T1 (de) |
| AU (1) | AU2003280753A1 (de) |
| CA (1) | CA2506580C (de) |
| DE (1) | DE60331677D1 (de) |
| ES (1) | ES2340266T3 (de) |
| WO (1) | WO2004044005A1 (de) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7608684B2 (en) * | 2002-11-12 | 2009-10-27 | Mochida Pharmaceuticals Co., Ltd. | Soluble CD14 antigen |
| DE60331677D1 (de) | 2002-11-12 | 2010-04-22 | Mochida Pharm Co Ltd | Kit zur untersuchung von menschlichem niedermolekulargewicht cd14 und antikörper |
| ES2406266T3 (es) | 2004-05-11 | 2013-06-06 | Mochida Pharmaceutical Co., Ltd. | Antígeno CD14 soluble novedoso |
| KR101025723B1 (ko) * | 2008-07-18 | 2011-04-04 | 주식회사 인포피아 | 광도파로를 포함하는 면역 크로마토그래피 분석 센서 및이를 이용한 측정방법 |
| US11041864B2 (en) * | 2011-01-11 | 2021-06-22 | Lsi Medience Corporation | Method for prediction of prognosis of sepsis |
| CN103562720B (zh) * | 2011-03-28 | 2016-08-17 | 美迪恩斯生命科技株式会社 | 全血检样的免疫测定方法和测定试剂盒 |
| US9297802B2 (en) | 2011-05-19 | 2016-03-29 | Mochida Pharmaceutical Co., Ltd. | Diagnosis of respiratory tract infectious diseases using urine specimens |
| KR101935071B1 (ko) | 2011-05-19 | 2019-01-03 | 모찌다 세이야쿠 가부시끼가이샤 | 혈액 검체를 사용한 호흡기 감염증의 진단 |
| JP5801895B2 (ja) * | 2011-08-12 | 2015-10-28 | 株式会社Ｌｓｉメディエンス | 全身性炎症反応症候群を伴わない術後感染症の検出方法 |
| WO2014178383A1 (ja) * | 2013-04-30 | 2014-11-06 | 持田製薬株式会社 | プレセプシン測定による発熱性好中球減少症の診断 |
| EP3112463B1 (de) * | 2014-02-26 | 2019-09-04 | Mochida Pharmaceutical Co., Ltd. | Neuartige anti-presepsin-antikörper |
| CA2996395C (en) * | 2015-08-25 | 2025-05-27 | Mochida Pharmaceutical Co., Ltd. | SPECIFICALLY PURIFIED ANTI-PRESEPSIN ANTIBODIES |
| EP4252629A3 (de) | 2016-12-07 | 2023-12-27 | Biora Therapeutics, Inc. | Verfahren, vorrichtungen und systeme zur detektion des magen-darm-trakts |
| JP2018140961A (ja) * | 2017-02-28 | 2018-09-13 | 持田製薬株式会社 | ビオチン化ｆ１１０６−１３−３抗体、その製造方法及びその用途 |
| EP3600416B1 (de) | 2017-03-30 | 2023-06-07 | Biora Therapeutics, Inc. | Behandlung einer erkrankung des gastrointestinaltraktes mit einem immunmodulatorischen mittel, das mit einer einnehmbaren vorrichtung freigesetzt wird. |
| JP6842168B2 (ja) * | 2017-05-12 | 2021-03-17 | 国立大学法人東北大学 | マイクロ水滴内イムノアッセイ |
| US20230041197A1 (en) | 2018-06-20 | 2023-02-09 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an immunomodulator |
| WO2019246317A1 (en) | 2018-06-20 | 2019-12-26 | Progenity, Inc. | Treatment of a disease or condition in a tissue originating from the endoderm |
| US20220249814A1 (en) | 2018-11-19 | 2022-08-11 | Progenity, Inc. | Methods and devices for treating a disease with biotherapeutics |
| CN115232211B (zh) * | 2019-11-19 | 2025-09-19 | 武汉全景生物技术有限公司 | 新的抗可溶性cd14亚型抗体及其应用 |
| EP4060338B1 (de) * | 2019-11-19 | 2024-07-17 | Shenzhen Mindray Bio-Medical Electronics Co., Ltd | Kit und verfahren zur gemischten detektion von pct und presepsin und dessen verwendung |
| EP4309722A3 (de) | 2019-12-13 | 2024-08-07 | Biora Therapeutics, Inc. | Einnehmbare vorrichtung zur abgabe eines therapeutischen mittels an den magen-darm-trakt |
| CN116500258A (zh) * | 2022-01-18 | 2023-07-28 | 广州达安基因股份有限公司 | 基于夹心法荧光免疫层析定量检测cd14的试剂盒及其应用 |
| CN119301455A (zh) | 2022-04-11 | 2025-01-10 | 生物梅里埃公司 | 用于减少新生儿抗生素治疗的ptx3生物标志物 |
| CN114839253B (zh) * | 2022-04-21 | 2024-10-01 | 深圳市第二人民医院(深圳市转化医学研究院) | 血清或血浆中低分子量蛋白定量分析方法及应用 |
| CN116444673B (zh) * | 2023-06-14 | 2023-09-15 | 北京汇智和源生物技术有限公司 | 人源膜cd14单克隆抗体及其制备方法和应用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4931385A (en) * | 1985-06-24 | 1990-06-05 | Hygeia Sciences, Incorporated | Enzyme immunoassays and immunologic reagents |
| DD286876A5 (de) | 1989-08-10 | 1991-02-07 | Ernst-Moritz-Arndt-Universitaet Greifswald,De | Verfahren zur bestimmung eines loeslichen humanen monozytenoberflaechenantigens |
| US5766593A (en) * | 1994-12-30 | 1998-06-16 | Amgen Inc. | Anti-inflammatory CD14 peptides |
| CN1330555A (zh) * | 1998-12-21 | 2002-01-09 | 路德维格癌症研究所 | 抗截短的vegf－d的抗体及其应用 |
| US7326568B2 (en) * | 1999-02-04 | 2008-02-05 | University Of Georgia Research Foundation, Inc. | Recombinant expression of heterologous nucleic acids in protozoa |
| WO2001022085A1 (en) | 1999-09-17 | 2001-03-29 | Mochida Pharmaceutical Co., Ltd. | Method of fractional measurement of soluble cd14 protein |
| EP1275713A4 (de) | 2000-03-31 | 2004-06-30 | Mochida Pharm Co Ltd | Tlr/cd14-bindender hemmstoff |
| JPWO2002042333A1 (ja) * | 2000-11-22 | 2004-03-25 | 持田製薬株式会社 | Ｃｄ１４／ｔｌｒ結合阻害作用を有する抗ｃｄ１４モノクローナル抗体 |
| DE60331677D1 (de) | 2002-11-12 | 2010-04-22 | Mochida Pharm Co Ltd | Kit zur untersuchung von menschlichem niedermolekulargewicht cd14 und antikörper |
-
2003
- 2003-11-12 DE DE60331677T patent/DE60331677D1/de not_active Expired - Lifetime
- 2003-11-12 AU AU2003280753A patent/AU2003280753A1/en not_active Abandoned
- 2003-11-12 AT AT03772718T patent/ATE460430T1/de not_active IP Right Cessation
- 2003-11-12 JP JP2005505675A patent/JP4081489B2/ja not_active Expired - Lifetime
- 2003-11-12 US US10/534,257 patent/US7465547B2/en not_active Expired - Lifetime
- 2003-11-12 WO PCT/JP2003/014389 patent/WO2004044005A1/ja not_active Ceased
- 2003-11-12 ES ES03772718T patent/ES2340266T3/es not_active Expired - Lifetime
- 2003-11-12 EP EP03772718A patent/EP1571160B1/de not_active Expired - Lifetime
- 2003-11-12 CA CA2506580A patent/CA2506580C/en not_active Expired - Lifetime
- 2003-11-12 CN CNB2003801031454A patent/CN100558746C/zh not_active Expired - Lifetime
-
2007
- 2007-12-04 US US11/987,746 patent/US7901900B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1571160A1 (de) | 2005-09-07 |
| CN100558746C (zh) | 2009-11-11 |
| CN1711283A (zh) | 2005-12-21 |
| AU2003280753A1 (en) | 2004-06-03 |
| EP1571160B1 (de) | 2010-03-10 |
| JPWO2004044005A1 (ja) | 2006-05-11 |
| WO2004044005A1 (ja) | 2004-05-27 |
| ATE460430T1 (de) | 2010-03-15 |
| US7901900B2 (en) | 2011-03-08 |
| US20070106067A1 (en) | 2007-05-10 |
| EP1571160A4 (de) | 2007-03-21 |
| CA2506580A1 (en) | 2004-05-27 |
| CA2506580C (en) | 2010-08-17 |
| ES2340266T3 (es) | 2010-06-01 |
| US7465547B2 (en) | 2008-12-16 |
| US20090029396A1 (en) | 2009-01-29 |
| JP4081489B2 (ja) | 2008-04-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |