DE60327250D1 - Modifizierte bace - Google Patents

Modifizierte bace

Info

Publication number: DE60327250D1
Authority: DE; Germany
Prior art keywords: bace; modified; modified bace
Prior art date: 2002-02-21
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

DE60327250T

Other languages

English (en)

Inventor

Kuo-Chen Chou

Jeffrey W Howe

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Pharmacia and Upjohn Co LLC

Original Assignee

Pharmacia and Upjohn Co LLC

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-02-21

Filing date

2003-02-21

Publication date

2009-05-28

2003-02-21 Application filed by Pharmacia and Upjohn Co LLC filed Critical Pharmacia and Upjohn Co LLC

2009-05-28 Application granted granted Critical

2009-05-28 Publication of DE60327250D1 publication Critical patent/DE60327250D1/de

2023-02-22 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6478—Aspartic endopeptidases (3.4.23)

Landscapes

Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Biomedical Technology (AREA)
Organic Chemistry (AREA)
Zoology (AREA)
Bioinformatics & Cheminformatics (AREA)
Wood Science & Technology (AREA)
Genetics & Genomics (AREA)
Microbiology (AREA)
Biotechnology (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
General Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Enzymes And Modification Thereof (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

DE60327250T 2002-02-21 2003-02-21 Modifizierte bace Expired - Lifetime DE60327250D1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US35865102P	2002-02-21	2002-02-21
PCT/US2003/005508 WO2003072733A2 (en)	2002-02-21	2003-02-21	Modified bace

Publications (1)

Publication Number	Publication Date
DE60327250D1 true DE60327250D1 (de)	2009-05-28

Family

ID=27765972

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE60327250T Expired - Lifetime DE60327250D1 (de)	2002-02-21	2003-02-21	Modifizierte bace

Country Status (7)

Country	Link
US (2)	US7273743B2 (de)
EP (1)	EP1572904B1 (de)
JP (1)	JP4272070B2 (de)
AU (1)	AU2003213252A1 (de)
CA (1)	CA2477243A1 (de)
DE (1)	DE60327250D1 (de)
WO (1)	WO2003072733A2 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7763609B2 (en)	2003-12-15	2010-07-27	Schering Corporation	Heterocyclic aspartyl protease inhibitors
US7479538B2 (en) *	2004-11-12	2009-01-20	The Zhabilov Trust	Irreversibly-inactivated pepsinogen fragment and pharmaceutical compositions comprising the same for detecting, preventing, and treating HIV
AU2006223070B2 (en) *	2005-03-14	2012-02-09	High Point Pharmaceuticals, Llc	Benzazole derivatives, compositions, and methods of use as B-secretase inhibitors

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5319689A (en) *	1992-03-12	1994-06-07	General Electric Company	Compactable phase-separator assembly for dual-phase nuclear reactor
US5744346A (en) *	1995-06-07	1998-04-28	Athena Neurosciences, Inc.	β-secretase
DE69635051T2 (de) *	1995-06-07	2006-06-14	Chiron Corp	Methode zur lösung, reinigung und rückfaltung von protein
ATE393227T1 (de)	1996-11-20	2008-05-15	Oklahoma Med Res Found	Klonierung und charakterisierung von napsin, einer aspartat-protease
GB9701684D0 (en) *	1997-01-28	1997-03-19	Smithkline Beecham Plc	Novel compounds
US6699671B1 (en) *	1998-09-24	2004-03-02	Pharmacia & Upjohn Company	Alzheimer's disease secretase, APP substrates therefor, and uses therefor
CN1502696A (zh)	1998-09-24	2004-06-09	��Ŷ��Լ��˾	阿尔茨海默氏疾病分泌酶
NZ534876A (en)	1999-02-10	2006-02-24	Elan Pharm Inc	Human beta-secretase enzyme, inhibitors and their compositions and uses
AU5773500A (en)	1999-06-28	2001-01-31	Board Of Trustees Of The University Of Illinois, The	Inhibitors of memapsin 2 and use thereof
CA2397786A1 (en)	1999-09-23	2001-04-05	Pharmacia & Upjohn Company	Alzheimer's disease secretase, app substrates therefor, and uses therefor

2003
- 2003-02-21 JP JP2003571421A patent/JP4272070B2/ja not_active Expired - Lifetime
- 2003-02-21 WO PCT/US2003/005508 patent/WO2003072733A2/en not_active Ceased
- 2003-02-21 DE DE60327250T patent/DE60327250D1/de not_active Expired - Lifetime
- 2003-02-21 EP EP03709301A patent/EP1572904B1/de not_active Expired - Lifetime
- 2003-02-21 US US10/372,473 patent/US7273743B2/en not_active Expired - Fee Related
- 2003-02-21 CA CA002477243A patent/CA2477243A1/en not_active Abandoned
- 2003-02-21 AU AU2003213252A patent/AU2003213252A1/en not_active Abandoned
2005
- 2005-10-31 US US11/263,057 patent/US7244606B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
EP1572904A2 (de)	2005-09-14
US20060094103A1 (en)	2006-05-04
EP1572904B1 (de)	2009-04-15
CA2477243A1 (en)	2003-09-04
WO2003072733A2 (en)	2003-09-04
WO2003072733A3 (en)	2005-08-11
US20040005691A1 (en)	2004-01-08
US7244606B2 (en)	2007-07-17
US7273743B2 (en)	2007-09-25
JP2005531292A (ja)	2005-10-20
AU2003213252A8 (en)	2003-09-09
JP4272070B2 (ja)	2009-06-03
AU2003213252A1 (en)	2003-09-09
EP1572904A4 (de)	2006-03-15

Publication	Publication Date	Title
ATE457980T1 (de)	2010-03-15	Aryloxime
ATE534648T1 (de)	2011-12-15	C-6-modifizierte indazolylpyrrolotriazine
NO20043728L (no)	2004-09-06	Astaksantinestere
DE50305852D1 (de)	2007-01-11	Einspritzventil
DE50306589D1 (de)	2007-04-05	Wischblatt
ATE318817T1 (de)	2006-03-15	Aza-arylpiperazine
ATE427876T1 (de)	2009-04-15	Luftkissenboot
DE50212349D1 (de)	2008-07-17	Hirurgie
DE50212360D1 (de)	2008-07-24	Anfahrhilfesteuerungsvorrichtung
DE60305663D1 (de)	2006-07-06	Kippschirm
DE50301200D1 (de)	2005-10-20	Wischblatt
ATE349458T1 (de)	2007-01-15	Etonogestrelester
DE50305301D1 (de)	2006-11-16	Einspritzventil
ATA1572002A (de)	2003-06-15	Managementspleisskassette
DE50302660D1 (de)	2006-05-11	Stopfmachine
DE50301960D1 (de)	2006-01-26	Hydrolager
BR0311793B1 (pt)	2013-12-31	Projétil de neblina
ATA4142004A (de)	2005-12-15	Trägerverbau
ATE469773T1 (de)	2010-06-15	Zugöse
DE50305973D1 (de)	2007-01-25	Auffangwanne
ATA19152002A (de)	2004-11-15	Hubkupplung
DE50209283D1 (de)	2007-03-08	Tropfbewässerungsrohr
DE60327250D1 (de)	2009-05-28	Modifizierte bace
ATE396192T1 (de)	2008-06-15	N-sulfonylaminothiazole
DE50300322D1 (de)	2005-03-31	Zylinderkopfdichtung

Legal Events

Date	Code	Title	Description
2010-05-06	8364	No opposition during term of opposition