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DE60326248D1 - Verbindungen, zusammensetzungen und verfahren zur behandlung von zellulären proliferativen erkrankungen - Google Patents

Verbindungen, zusammensetzungen und verfahren zur behandlung von zellulären proliferativen erkrankungen

Info

Publication number
DE60326248D1
DE60326248D1 DE60326248T DE60326248T DE60326248D1 DE 60326248 D1 DE60326248 D1 DE 60326248D1 DE 60326248 T DE60326248 T DE 60326248T DE 60326248 T DE60326248 T DE 60326248T DE 60326248 D1 DE60326248 D1 DE 60326248D1
Authority
DE
Germany
Prior art keywords
compounds
compositions
methods
cellular proliferative
proliferative disorders
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60326248T
Other languages
English (en)
Inventor
Andrew Mcdonald
David J Morgans
Gustave Bergnes
Dashyant Dhanak
Steven David Knight
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cytokinetics Inc
Original Assignee
Cytokinetics Inc
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cytokinetics Inc, SmithKline Beecham Corp filed Critical Cytokinetics Inc
Application granted granted Critical
Publication of DE60326248D1 publication Critical patent/DE60326248D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/34—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D309/36—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
    • C07D309/38—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms one oxygen atom in position 2 or 4, e.g. pyrones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Vascular Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyrane Compounds (AREA)
DE60326248T 2002-07-17 2003-07-17 Verbindungen, zusammensetzungen und verfahren zur behandlung von zellulären proliferativen erkrankungen Expired - Fee Related DE60326248D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39669002P 2002-07-17 2002-07-17
PCT/US2003/022466 WO2004006865A2 (en) 2002-07-17 2003-07-17 Compounds, compositions, and methods

Publications (1)

Publication Number Publication Date
DE60326248D1 true DE60326248D1 (de) 2009-04-02

Family

ID=30116052

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60326248T Expired - Fee Related DE60326248D1 (de) 2002-07-17 2003-07-17 Verbindungen, zusammensetzungen und verfahren zur behandlung von zellulären proliferativen erkrankungen

Country Status (7)

Country Link
US (2) US6949538B2 (de)
EP (1) EP1539727B1 (de)
JP (1) JP2005533119A (de)
AT (1) ATE423110T1 (de)
AU (1) AU2003252025A1 (de)
DE (1) DE60326248D1 (de)
WO (1) WO2004006865A2 (de)

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JP2005539062A (ja) * 2002-09-13 2005-12-22 サイトキネティクス・インコーポレーテッド 化合物、組成物および方法
US20060270689A1 (en) * 2003-03-07 2006-11-30 Astrazeneca Ab Novel Fused Heterocycles and Uses Thereof
WO2006018628A1 (en) * 2003-03-07 2006-02-23 Astrazeneca Ab Enantiomers of selected fused pyrimidones and uses in the treatment and preventi on of cancer
WO2005042697A2 (en) * 2003-10-06 2005-05-12 Cytokinetics, Inc. Compounds, compositions and methods
PL1753723T3 (pl) 2004-05-21 2009-01-30 Novartis Vaccines & Diagnostics Inc Podstawione pochodne chinoliny jako inhibitory kinezyn mitotycznych
KR101170925B1 (ko) 2004-06-18 2012-08-07 노바티스 백신즈 앤드 다이아그노스틱스 인코포레이티드 암 치료용 키네신 방추 단백질 (ｋｓｐ) 억제제로서의ｎ-(1-(1-벤질-4-페닐-1ｈ-이미다졸-2-일)-2,2-디메틸프로필)벤자미드 유도체 및 관련 화합물
CA2574204A1 (en) * 2004-07-22 2006-01-26 Astrazeneca Ab Fused pyrimidones useful in the treatment and the prevention of cancer
US20060041128A1 (en) * 2004-08-18 2006-02-23 Astrazeneca Ab Selected fused heterocyclics and uses thereof
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KR20070072598A (ko) 2004-10-19 2007-07-04 노바티스 백신즈 앤드 다이아그노스틱스 인코포레이티드 인돌 및 벤지미다졸 유도체
JP2008524329A (ja) * 2004-12-21 2008-07-10 メルク エンド カムパニー インコーポレーテッド 有糸分裂キネシン阻害剤
JP2009514866A (ja) * 2005-11-02 2009-04-09 サイトキネティクス・インコーポレーテッド ある種の化学物質、組成物、および方法
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GEP20125415B (en) 2007-01-05 2012-03-12 Novartis Ag Imidazole derivatives as kinesin spindle protein inhibitors (eg-5)

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Also Published As

Publication number Publication date
US20060004073A1 (en) 2006-01-05
AU2003252025A8 (en) 2004-02-02
WO2004006865A2 (en) 2004-01-22
EP1539727B1 (de) 2009-02-18
US6949538B2 (en) 2005-09-27
AU2003252025A1 (en) 2004-02-02
WO2004006865A3 (en) 2004-07-01
JP2005533119A (ja) 2005-11-04
EP1539727A4 (de) 2007-04-04
US20040116400A1 (en) 2004-06-17
ATE423110T1 (de) 2009-03-15
EP1539727A2 (de) 2005-06-15

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: CYTOKINETICS, INC., SOUTH SAN FRANCISCO, CALIF, US

8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee