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DE60323981D1 - Zimtsäureamidderivate - Google Patents

Zimtsäureamidderivate

Info

Publication number
DE60323981D1
DE60323981D1 DE60323981T DE60323981T DE60323981D1 DE 60323981 D1 DE60323981 D1 DE 60323981D1 DE 60323981 T DE60323981 T DE 60323981T DE 60323981 T DE60323981 T DE 60323981T DE 60323981 D1 DE60323981 D1 DE 60323981D1
Authority
DE
Germany
Prior art keywords
zimtsäureamidderivate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60323981T
Other languages
English (en)
Inventor
Synese Jolidon
Sarmiento Rosa Maria Rodriguez
Andrew William Thomas
Wolfgang Wostl
Rene Wyler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Application granted granted Critical
Publication of DE60323981D1 publication Critical patent/DE60323981D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • C07C255/49Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/54Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and etherified hydroxy groups bound to the carbon skeleton
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/32Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C07C235/34Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE60323981T 2002-07-15 2003-07-07 Zimtsäureamidderivate Expired - Fee Related DE60323981D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP02015583 2002-07-15
PCT/EP2003/007231 WO2004007429A1 (en) 2002-07-15 2003-07-07 Cinnamide derivatives

Publications (1)

Publication Number Publication Date
DE60323981D1 true DE60323981D1 (de) 2008-11-20

Family

ID=30011071

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60323981T Expired - Fee Related DE60323981D1 (de) 2002-07-15 2003-07-07 Zimtsäureamidderivate

Country Status (20)

Country Link
US (1) US6900354B2 (de)
EP (1) EP1523469B1 (de)
JP (1) JP4108679B2 (de)
KR (1) KR20050029206A (de)
CN (1) CN1305838C (de)
AR (1) AR040489A1 (de)
AT (1) ATE410407T1 (de)
AU (1) AU2003281030B2 (de)
BR (1) BR0312658A (de)
CA (1) CA2493372A1 (de)
DE (1) DE60323981D1 (de)
ES (1) ES2314219T3 (de)
MX (1) MXPA05000583A (de)
PA (1) PA8577201A1 (de)
PE (1) PE20040667A1 (de)
PL (1) PL373390A1 (de)
RU (1) RU2318802C2 (de)
TW (1) TW200404760A (de)
UY (1) UY27894A1 (de)
WO (1) WO2004007429A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1588704A1 (de) * 2004-04-22 2005-10-26 Newron Pharmaceuticals S.p.A. Alpha-aminoamidderivate zur Behandlung des Restless-Leg-Syndroms und der Suchterkrankungen
MY149038A (en) 2004-05-26 2013-07-15 Eisai R&D Man Co Ltd Cinnamide compound
AU2005297966B2 (en) * 2004-10-26 2010-12-23 Eisai R & D Management Co., Ltd. Amorphous object of cinnamide compound
KR20070094666A (ko) 2005-02-25 2007-09-20 에프. 호프만-라 로슈 아게 약제 물질 분산성이 향상된 정제
WO2006127133A2 (en) 2005-04-01 2006-11-30 Wellstat Therapeutics Corporation Compounds for the treatment of metabolic disorders
US8138209B2 (en) * 2005-07-13 2012-03-20 Jenrin Discovery, Inc. Substituted picolinamides as MAO-B inhibitors useful for treating obesity
PL209602B1 (pl) 2005-10-20 2011-09-30 Inst Chemii Bioorg Pan Sposób otrzymywania amidu kwasu 3-(4-hydroksyfenylo)propanowego
CN101309916A (zh) * 2005-11-18 2008-11-19 卫材R&D管理有限公司 制备肉桂酰胺衍生物的方法
US20090048448A1 (en) * 2005-11-18 2009-02-19 Ikuo Kushida Salts of cynnamide compound or solvates thereof
TWI370130B (en) * 2005-11-24 2012-08-11 Eisai R&D Man Co Ltd Two cyclic cinnamide compound
ZA200803939B (en) * 2005-11-24 2009-10-28 Eisai R&D Man Co Ltd Morpholine type cinnamide compound
EP1953154A4 (de) 2005-11-24 2013-11-20 Eisai R&D Man Co Ltd Morpholin-cinnamid-verbindung
TWI378091B (en) 2006-03-09 2012-12-01 Eisai R&D Man Co Ltd Multi-cyclic cinnamide derivatives
AR062095A1 (es) * 2006-07-28 2008-10-15 Eisai R&D Man Co Ltd Profarmaco de compuesto cinamida
US20080207900A1 (en) * 2007-02-28 2008-08-28 Teiji Kimura Two cyclic oxomorphorin derivatives
KR20100016580A (ko) * 2007-05-16 2010-02-12 에자이 알앤드디 매니지먼트 가부시키가이샤 신나미드 유도체의 원폿 제조 방법
US7986144B2 (en) * 2007-07-26 2011-07-26 Schlumberger Technology Corporation Sensor and insulation layer structure for well logging instruments
WO2009028588A1 (ja) 2007-08-31 2009-03-05 Eisai R & D Management Co., Ltd. 多環式化合物
US7935815B2 (en) * 2007-08-31 2011-05-03 Eisai R&D Management Co., Ltd. Imidazoyl pyridine compounds and salts thereof
EP2239265A1 (de) * 2008-01-28 2010-10-13 Eisai R&D Management Co., Ltd. Kristalline cinnamidverbindungen oder salze daraus
NL2005655A (en) 2009-12-09 2011-06-14 Asml Netherlands Bv A lithographic apparatus and a device manufacturing method.
CN104030941B (zh) * 2014-06-23 2016-04-27 常州大学 一种3-(4-羟基苯基)丙酰胺的合成方法
CN107011313B (zh) 2016-01-27 2021-11-30 天士力医药集团股份有限公司 取代桂皮酰胺衍生物在制备抗焦虑药物中的应用
RU2022101021A (ru) 2018-01-10 2022-03-18 Брайтсид, Инк. Способ модуляции метаболизма

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2645019A1 (de) * 1989-03-30 1990-10-05 Fournier Innovation Synergie
US5679715A (en) 1995-06-07 1997-10-21 Harris; Richard Y. Method for treating multiple sclerosis
US6239181B1 (en) 1996-03-15 2001-05-29 Somerset Pharmaceuticals, Inc. Method for preventing and treating peripheral neurophathy by administering selegiline
AU1359801A (en) 1999-11-05 2001-06-06 Vela Pharmaceuticals Inc. Methods and compositions for treating reward deficiency syndrome

Also Published As

Publication number Publication date
TW200404760A (en) 2004-04-01
JP4108679B2 (ja) 2008-06-25
KR20050029206A (ko) 2005-03-24
MXPA05000583A (es) 2005-04-19
US6900354B2 (en) 2005-05-31
RU2318802C2 (ru) 2008-03-10
EP1523469B1 (de) 2008-10-08
JP2005533092A (ja) 2005-11-04
WO2004007429A1 (en) 2004-01-22
RU2005104104A (ru) 2005-10-10
AU2003281030A1 (en) 2004-02-02
PL373390A1 (en) 2005-08-22
AU2003281030B2 (en) 2009-05-28
US20040034096A1 (en) 2004-02-19
AR040489A1 (es) 2005-04-06
ES2314219T3 (es) 2009-03-16
BR0312658A (pt) 2005-04-26
CN1305838C (zh) 2007-03-21
UY27894A1 (es) 2003-12-31
PA8577201A1 (es) 2004-02-07
ATE410407T1 (de) 2008-10-15
PE20040667A1 (es) 2004-09-25
CN1665774A (zh) 2005-09-07
CA2493372A1 (en) 2004-01-22
EP1523469A1 (de) 2005-04-20

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee