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DE60323812D1 - Apparat zur zurückhaltung von magnetteilchen in einer durchflusszelle - Google Patents

Apparat zur zurückhaltung von magnetteilchen in einer durchflusszelle

Info

Publication number
DE60323812D1
DE60323812D1 DE60323812T DE60323812T DE60323812D1 DE 60323812 D1 DE60323812 D1 DE 60323812D1 DE 60323812 T DE60323812 T DE 60323812T DE 60323812 T DE60323812 T DE 60323812T DE 60323812 D1 DE60323812 D1 DE 60323812D1
Authority
DE
Germany
Prior art keywords
magnetic particles
flow
microchannel
flow cell
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60323812T
Other languages
English (en)
Inventor
Amar Rida
Martin Gijs
Olivier Elsenhans
Goran Savatic
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Roche Diagnostics GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Diagnostics GmbH filed Critical Roche Diagnostics GmbH
Application granted granted Critical
Publication of DE60323812D1 publication Critical patent/DE60323812D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00—Magnetic separation
    • B03C1/02—Magnetic separation acting directly on the substance being separated
    • B03C1/035—Open gradient magnetic separators, i.e. separators in which the gap is unobstructed, characterised by the configuration of the gap
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00—Magnetic separation
    • B03C1/02—Magnetic separation acting directly on the substance being separated
    • B03C1/025—High gradient magnetic separators
    • B03C1/031—Component parts; Auxiliary operations
    • B03C1/033—Component parts; Auxiliary operations characterised by the magnetic circuit
    • B03C1/0335—Component parts; Auxiliary operations characterised by the magnetic circuit using coils
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00—Magnetic separation
    • B03C1/02—Magnetic separation acting directly on the substance being separated
    • B03C1/28—Magnetic plugs and dipsticks
    • B03C1/288—Magnetic plugs and dipsticks disposed at the outer circumference of a recipient
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C2201/00—Details of magnetic or electrostatic separation
    • B03C2201/18—Magnetic separation whereby the particles are suspended in a liquid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C2201/00—Details of magnetic or electrostatic separation
    • B03C2201/26—Details of magnetic or electrostatic separation for use in medical or biological applications

Landscapes

  • Physical Or Chemical Processes And Apparatus (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
DE60323812T 2002-01-23 2003-01-22 Apparat zur zurückhaltung von magnetteilchen in einer durchflusszelle Expired - Lifetime DE60323812D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP02075267A EP1331035A1 (de) 2002-01-23 2002-01-23 Apparat zum Zurückhalten von Magnetteilchen in einer von einer Flüssigkeit durchströmte Zelle
PCT/EP2003/000694 WO2003061835A1 (en) 2002-01-23 2003-01-22 Apparatus for retaining magnetic particles within a flow-through cell

Publications (1)

Publication Number Publication Date
DE60323812D1 true DE60323812D1 (de) 2008-11-13

Family

ID=8185560

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60323812T Expired - Lifetime DE60323812D1 (de) 2002-01-23 2003-01-22 Apparat zur zurückhaltung von magnetteilchen in einer durchflusszelle

Country Status (6)

Country Link
US (1) US7601265B2 (de)
EP (3) EP1331035A1 (de)
JP (1) JP2005515455A (de)
AT (1) ATE409523T1 (de)
DE (1) DE60323812D1 (de)
WO (1) WO2003061835A1 (de)

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JP2006010535A (ja) 2004-06-25 2006-01-12 Canon Inc 標的物質捕捉方法および装置
KR100634525B1 (ko) * 2004-11-23 2006-10-16 삼성전자주식회사 복수 개의 전자석이 배치되어 있는 마이크로채널을포함하는 미세유동 장치, 그를 이용하여 시료를 혼합하는방법 및 세포를 용해하는 방법
CN100418874C (zh) * 2004-12-28 2008-09-17 东南大学 磁场诱导沉积方法制备磁性纳米间隙电极
US7985340B2 (en) 2005-12-02 2011-07-26 Invitrogen Dynal As Magnetic separator
WO2007063529A2 (en) * 2005-12-02 2007-06-07 Invitrogen Dynal As Magnetic separator
CN100457633C (zh) * 2006-01-25 2009-02-04 北京科技大学 一种磁性过渡金属氧化物纳米颗粒液相生长过程中颗粒粒径的控制方法
US8870446B2 (en) * 2006-06-21 2014-10-28 Spinomix S.A. Device and method for manipulating and mixing magnetic particles in a liquid medium
US8999732B2 (en) * 2006-06-21 2015-04-07 Spinomix, S.A. Method for manipulating magnetic particles in a liquid medium
US8585279B2 (en) * 2006-06-21 2013-11-19 Spinomix S.A. Device and method for manipulating and mixing magnetic particles in a liquid medium
WO2008007270A2 (en) * 2006-06-21 2008-01-17 Spinomix S.A. A method for manipulating magnetic particles in a liquid medium
WO2008116941A1 (es) 2007-03-26 2008-10-02 Fundación Gaiker Método y dispositivo para la detección de material genético mediante reacción en cadena de polimerasa
EP2185289B1 (de) 2007-08-13 2015-02-25 Agency for Science, Technology and Research Mikrofluidtrennsystem
DE102008047843A1 (de) * 2008-09-18 2010-04-22 Siemens Aktiengesellschaft Trenneinrichtung zur Trennung von in einer durch einen Trennkanal strömenden Suspension transportierten magnetisierbaren und nichtmagnetisierbaren Teilchen
DE102008047855A1 (de) * 2008-09-18 2010-04-22 Siemens Aktiengesellschaft Trenneinrichtung zur Trennung von in einer durch einen Trennkanal strömenden Suspension transportierten magnetisierbaren und nichtmagnetisierbaren Teilchen
EP2208531A1 (de) 2008-12-30 2010-07-21 Atonomics A/S Verteilung von Partikeln in einem Kapillarkanal durch Anwendung eines Magnetfelds
KR101080044B1 (ko) * 2009-02-27 2011-11-04 동아대학교 산학협력단 영구자석과 자성입자를 이용한 마이크로 채널형 유체 혼합기 시스템
KR101080045B1 (ko) * 2009-02-27 2011-11-04 동아대학교 산학협력단 마이크로 채널형 유체 혼합기 시스템 및 마이크로 채널을 이용한 유체 혼합방법
CH700770A2 (de) * 2009-04-15 2010-10-15 Philippe Saint Ger Ag Verfahren zum Unterstützen und/oder Intensivieren einer physikalischen und/oder chemischen Reaktion und eine Reaktionseinrichtung zum Ausführen des Verfahrens.
EP2701851B1 (de) * 2011-04-29 2024-04-24 Becton Dickinson and Company Sammelsystem zur immobilisierung fluidischer inline-teilchen sowie verfahren dafür
FR2995225B1 (fr) 2012-09-07 2014-10-03 Jean-Louis Viovy Systeme microfluidique presentant un lit de particules magnetiques
CN104614224A (zh) * 2015-02-11 2015-05-13 清华大学 基于动态磁珠塞的样品富集方法及系统
CN105772123B (zh) * 2016-04-12 2017-09-29 华中科技大学 一种基于微流控通道的磁分离方法及装置
EP3692307B1 (de) 2017-10-02 2021-08-25 Adey Holdings (2008) Limited Messung des magnetischen schmutzaufbaus in einem magnetfilter
CN108160488B (zh) * 2017-12-21 2021-04-30 浙江金朗博药业有限公司 一种高效的阿莫西林胶囊筛选装置
CN113218737A (zh) * 2020-01-21 2021-08-06 陈琪 一种通过使磁微粒往复运动来分离磁微粒的方法和装置
CN119368327B (zh) * 2024-12-31 2025-04-29 山东华特磁电科技股份有限公司 一种多腔式大型电磁浆料高梯度磁选机

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1141536A (fr) * 1956-01-19 1957-09-03 Séparateur magnétique en milieu aqueux
GB1077242A (en) * 1965-04-09 1967-07-26 English Clays Lovering Pochin A method of improving the whiteness of clays
US4209394A (en) * 1979-02-05 1980-06-24 Massachusetts Institute Of Technology Magnetic separator having a multilayer matrix, method and apparatus
DE3522365A1 (de) * 1985-06-22 1987-01-02 Bayer Ag Trenngeraet fuer magnetische partikel aus fluessiger phase
US5541072A (en) * 1994-04-18 1996-07-30 Immunivest Corporation Method for magnetic separation featuring magnetic particles in a multi-phase system
WO1994020855A1 (en) * 1993-03-04 1994-09-15 Sapidyne, Inc. Assay flow apparatus and method
JPH07232097A (ja) * 1994-02-24 1995-09-05 Power Reactor & Nuclear Fuel Dev Corp 磁気クロマトグラフィー法による群分離方法
US5568869A (en) 1994-12-06 1996-10-29 S.G. Frantz Company, Inc. Methods and apparatus for making continuous magnetic separations
US5655665A (en) * 1994-12-09 1997-08-12 Georgia Tech Research Corporation Fully integrated micromachined magnetic particle manipulator and separator
JP4245272B2 (ja) 1997-10-09 2009-03-25 サーモ・ブラック・クローソン・インコーポレーテッド 製紙用パルプ精製機制御装置および方法
US6241894B1 (en) * 1997-10-10 2001-06-05 Systemix High gradient magnetic device and method for cell separation or purification
US6159378A (en) * 1999-02-23 2000-12-12 Battelle Memorial Institute Apparatus and method for handling magnetic particles in a fluid
DE19938372A1 (de) * 1999-08-09 2001-03-08 Diagnostikforschung Inst Verfahren und Vorrichtung zur Trennung magnetischer Teilchen

Also Published As

Publication number Publication date
ATE409523T1 (de) 2008-10-15
EP1467817B1 (de) 2008-10-01
WO2003061835A1 (en) 2003-07-31
EP1661625A1 (de) 2006-05-31
JP2005515455A (ja) 2005-05-26
EP1331035A1 (de) 2003-07-30
US20050208464A1 (en) 2005-09-22
EP1467817A1 (de) 2004-10-20
US7601265B2 (en) 2009-10-13

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