[go: up one dir, main page]

DE60323625D1 - Verfahren zur charakterisierung der ausgangssignale eines microarrays - Google Patents

Verfahren zur charakterisierung der ausgangssignale eines microarrays

Info

Publication number
DE60323625D1
DE60323625D1 DE60323625T DE60323625T DE60323625D1 DE 60323625 D1 DE60323625 D1 DE 60323625D1 DE 60323625 T DE60323625 T DE 60323625T DE 60323625 T DE60323625 T DE 60323625T DE 60323625 D1 DE60323625 D1 DE 60323625D1
Authority
DE
Germany
Prior art keywords
microarray
characterizing
output signals
signals
output
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60323625T
Other languages
English (en)
Inventor
Sandeep Gulati
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vialogy LLC
Original Assignee
Vialogy LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vialogy LLC filed Critical Vialogy LLC
Application granted granted Critical
Publication of DE60323625D1 publication Critical patent/DE60323625D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/251—Colorimeters; Construction thereof
    • G01N21/253—Colorimeters; Construction thereof for batch operation, i.e. multisample apparatus
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/0002—Inspection of images, e.g. flaw detection
    • G06T7/0012—Biomedical image inspection
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/10—Segmentation; Edge detection
    • G06T7/11—Region-based segmentation
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/10—Segmentation; Edge detection
    • G06T7/12—Edge-based segmentation
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/10—Image acquisition modality
    • G06T2207/10056—Microscopic image
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/10—Image acquisition modality
    • G06T2207/10064—Fluorescence image
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/20—Special algorithmic details
    • G06T2207/20112—Image segmentation details
    • G06T2207/20156—Automatic seed setting
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/20—Special algorithmic details
    • G06T2207/20112—Image segmentation details
    • G06T2207/20168—Radial search
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/30—Subject of image; Context of image processing
    • G06T2207/30004—Biomedical image processing
    • G06T2207/30072—Microarray; Biochip, DNA array; Well plate

Landscapes

  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Theoretical Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Medical Informatics (AREA)
  • Pathology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Quality & Reliability (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Evolutionary Biology (AREA)
  • Biotechnology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Image Processing (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
DE60323625T 2002-05-03 2003-05-05 Verfahren zur charakterisierung der ausgangssignale eines microarrays Expired - Lifetime DE60323625D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37752002P 2002-05-03 2002-05-03
PCT/US2003/014182 WO2003093810A1 (en) 2002-05-03 2003-05-05 System and method for characterizing microarray output data

Publications (1)

Publication Number Publication Date
DE60323625D1 true DE60323625D1 (de) 2008-10-30

Family

ID=29401518

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60323625T Expired - Lifetime DE60323625D1 (de) 2002-05-03 2003-05-05 Verfahren zur charakterisierung der ausgangssignale eines microarrays

Country Status (5)

Country Link
US (2) US7006680B2 (de)
EP (1) EP1502098B1 (de)
AU (1) AU2003245269A1 (de)
DE (1) DE60323625D1 (de)
WO (1) WO2003093810A1 (de)

Families Citing this family (69)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040111219A1 (en) * 1999-02-22 2004-06-10 Sandeep Gulati Active interferometric signal analysis in software
US7352373B2 (en) * 2003-09-30 2008-04-01 Sharp Laboratories Of America, Inc. Systems and methods for multi-dimensional dither structure creation and application
US20060106706A1 (en) * 2004-03-16 2006-05-18 Labonty Joseph W Apparatus and method for document processing
EP2290072B1 (de) 2004-05-28 2014-12-17 Asuragen, Inc. Verfahren und Zusammensetzungen mit MicroRNA
WO2006130165A2 (en) * 2004-09-02 2006-12-07 Vialogy Corp. Detecting events of interest using quantum resonance interferometry
AU2005333165B2 (en) 2004-11-12 2012-07-19 Asuragen, Inc. Methods and compositions involving miRNA and miRNA inhibitor molecules
US20060142948A1 (en) * 2004-12-23 2006-06-29 Minor James M Multiple-channel bias removal methods with little dependence on population size
JP4427001B2 (ja) * 2005-05-13 2010-03-03 オリンパス株式会社 画像処理装置、画像処理プログラム
US20070269818A1 (en) * 2005-12-28 2007-11-22 Affymetrix, Inc. Carbohydrate arrays
US7480047B1 (en) * 2005-12-28 2009-01-20 Kla-Tencor Corporation Time-domain computation of scattering spectra for use in spectroscopic metrology
US8112247B2 (en) * 2006-03-24 2012-02-07 International Business Machines Corporation Resource adaptive spectrum estimation of streaming data
US20070296842A1 (en) * 2006-06-09 2007-12-27 Raymond Samuel Connell Spiral image capture system
US8009889B2 (en) 2006-06-27 2011-08-30 Affymetrix, Inc. Feature intensity reconstruction of biological probe array
WO2008019382A2 (en) * 2006-08-07 2008-02-14 Vialogy Llc.. Quantum resonance interferometry for detecting signals
CA2664383C (en) 2006-09-19 2017-08-22 Asuragen, Inc. Micrornas differentially expressed in pancreatic diseases and uses thereof
CA2663962A1 (en) 2006-09-19 2008-03-27 Asuragen, Inc. Mir-15, mir-26, mir-31,mir-145, mir-147, mir-188, mir-215, mir-216, mir-331, mmu-mir-292-3p regulated genes and pathways as targets for therapeutic intervention
DK2156370T3 (da) 2007-05-14 2012-01-23 Historx Inc Kompartmentadskillelse ved pixelkarakterisering under anvendelse af billeddata-clustering
US7907271B2 (en) * 2007-06-15 2011-03-15 Historx, Inc. Method and system for standardizing microscope instruments
CA2604317C (en) 2007-08-06 2017-02-28 Historx, Inc. Methods and system for validating sample images for quantitative immunoassays
CA2596204C (en) * 2007-08-07 2019-02-26 Historx, Inc. Method and system for determining an optimal dilution of a reagent
WO2009029810A1 (en) * 2007-08-31 2009-03-05 Historx, Inc. Automatic exposure time selection for imaging tissue
US20090070730A1 (en) * 2007-09-06 2009-03-12 Synopsys, Inc. Method and apparatus for modeling a vectorial polarization effect in an optical lithography system
WO2009036332A1 (en) 2007-09-14 2009-03-19 Asuragen, Inc. Micrornas differentially expressed in cervical cancer and uses thereof
US8385997B2 (en) 2007-12-11 2013-02-26 Tokitae Llc Spectroscopic detection of malaria via the eye
US8504129B2 (en) * 2007-12-11 2013-08-06 Tokitae Llc Systems, devices, and methods including enhanced dark field detection of hemozoin nanoparticles
EP2990487A1 (de) 2008-05-08 2016-03-02 Asuragen, INC. Zusammensetzungen und verfahren in zusammenhang mit der mirna-modulation von neovaskularisation oder angiogenese
US20100034444A1 (en) * 2008-08-07 2010-02-11 Helicos Biosciences Corporation Image analysis
US8351667B2 (en) * 2008-08-15 2013-01-08 Sti Medical Systems, Llc Methods of contrast enhancement for images having blood vessel structures
ES2573945T3 (es) 2008-09-16 2016-06-13 Novartis Ag Cuantificación reproducible de expresión de biomarcadores
US8243075B2 (en) * 2008-10-14 2012-08-14 Autodesk, Inc. Graphics processing unit accelerated dynamic radial tessellation
US8482560B2 (en) * 2008-12-31 2013-07-09 Intel Corporation Image forming techniques
WO2010111656A2 (en) * 2009-03-27 2010-09-30 Life Technologies Corporation Systems and methods for assessing images
JP6059014B2 (ja) 2009-06-19 2017-01-11 アリゾナ ボード オブ リージェンツ ア ボディー コーポレート アクティング オン ビハーフ オブ アリゾナ ステイト ユニバーシティＡＲＩＺＯＮＡ ＢＯＡＲＤ ＯＦ ＲＥＧＥＮＴＳ，ａ ｂｏｄｙ ｃｏｒｐｏｒａｔｅ ａｃｔｉｎｇ ｏｎ ｂｅｈａｌｆ ｏｆ ＡＲＩＺＯＮＡ ＳＴＡＴＥ ＵＮＩＶＥＲＳＩＴＹ 試料の構成成分の検出において使用されるデバイスを製造する方法およびペプチドアレイ
US8811745B2 (en) * 2010-01-20 2014-08-19 Duke University Segmentation and identification of layered structures in images
US8781184B2 (en) * 2010-02-10 2014-07-15 Tokitae Llc Systems, devices, and methods for detection of malaria
US9044141B2 (en) * 2010-02-10 2015-06-02 Tokitae Llc Systems, devices, and methods including a dark-field reflected-illumination apparatus
EP2542678B1 (de) 2010-03-04 2017-04-12 InteRNA Technologies B.V. Mirna-molekül, das durch seine quelle definiert ist, und seine therapeutischen verwendungen bei emt assoziierten krebs
US8649980B2 (en) 2010-03-05 2014-02-11 Vialogy Llc Active noise injection computations for improved predictability in oil and gas reservoir characterization and microseismic event analysis
US8612156B2 (en) * 2010-03-05 2013-12-17 Vialogy Llc Active noise injection computations for improved predictability in oil and gas reservoir discovery and characterization
NZ704322A (en) 2010-07-06 2016-07-29 Interna Technologies Bv Mirna and its diagnostic and therapeutic uses in diseases or conditions associated with melanoma, or in diseases or conditions associated with activated braf pathway
US9158369B2 (en) * 2010-10-12 2015-10-13 Tactonic Technologies, Llc Sensors having a connecting frame and method for composite sensors
EP2640851A2 (de) 2010-11-17 2013-09-25 Asuragen, Inc. Mirna als biomarker zur unterscheidung zwischen benignen und malignen neoplasien der schilddrüse
EP2474617A1 (de) 2011-01-11 2012-07-11 InteRNA Technologies BV MIR zur Behandlung von Neoangiogenese
US20140057295A1 (en) 2011-02-28 2014-02-27 Barbara J. Stegmann Anti-mullerian hormone changes in pregnancy and prediction of adverse pregnancy outcomes and gender
US9644241B2 (en) 2011-09-13 2017-05-09 Interpace Diagnostics, Llc Methods and compositions involving miR-135B for distinguishing pancreatic cancer from benign pancreatic disease
US20130157884A1 (en) 2011-10-26 2013-06-20 Asuragen, Inc. Methods and compositions involving mirna expression levels for distinguishing pancreatic cysts
WO2013063544A1 (en) 2011-10-27 2013-05-02 Asuragen, Inc. Mirnas as diagnostic biomarkers to distinguish benign from malignant thyroid tumors
CN102749290B (zh) * 2012-07-02 2014-12-03 浙江大学 一种樱桃树冠层树枝生长状态的检测方法
WO2014007623A1 (en) 2012-07-03 2014-01-09 Interna Technologies B.V. Diagnostic portfolio and its uses
WO2014055117A1 (en) 2012-10-04 2014-04-10 Asuragen, Inc. Diagnostic mirnas for differential diagnosis of incidental pancreatic cystic lesions
US9944992B2 (en) 2013-03-15 2018-04-17 The University Of Chicago Methods and compositions related to T-cell activity
WO2014151551A1 (en) 2013-03-15 2014-09-25 Baylor Research Institute Ulcerative colitis (uc)-associated colorectal neoplasia markers
US9868992B2 (en) 2013-03-15 2018-01-16 Baylor Research Institute Tissue and blood-based miRNA biomarkers for the diagnosis, prognosis and metastasis-predictive potential in colorectal cancer
WO2014153369A1 (en) * 2013-03-18 2014-09-25 Life Technologies Corporation Methods and systems for analyzing biological reaction systems
US10758886B2 (en) 2015-09-14 2020-09-01 Arizona Board Of Regents On Behalf Of Arizona State University Conditioned surfaces for in situ molecular array synthesis
CN105467641B (zh) * 2015-11-30 2018-10-12 信利（惠州）智能显示有限公司 像素排列方法
AU2017281039A1 (en) 2016-06-20 2019-01-24 Healthtell Inc. Methods for differential diagnosis of autoimmune diseases
AU2017281040A1 (en) 2016-06-20 2019-01-24 Healthtell Inc. Methods for diagnosis and treatment of autoimmune diseases
AU2017357818A1 (en) 2016-11-11 2019-05-30 HealthTell, Inc. Methods for identifying candidate biomarkers
CN108460770B (zh) * 2016-12-13 2020-03-10 华为技术有限公司 抠图方法及装置
WO2019055618A1 (en) 2017-09-15 2019-03-21 Arizona Board Of Regents On Behalf Of Arizona State University METHODS OF CLASSIFYING RESPONSES TO ANTICANCER IMMUNOTHERAPY
EP3704250A1 (de) 2017-11-03 2020-09-09 InteRNA Technologies B.V. Mirna-molekül, äquivalent, antagomir oder quelle davon zur behandlung und/oder diagnose eines zustands und/oder einer erkrankung im zusammenhang mit neuronaler defizienz oder neuronaler (re)generation
DE102018217395A1 (de) * 2018-10-11 2020-04-16 Robert Bosch Gmbh Verfahren zur Bestimmung der Wertigkeit von Radarmesswerten zur Bestimmung eines Belegungszustands eines Stellplatzes
CN109410190B (zh) * 2018-10-15 2022-04-29 广东电网有限责任公司 基于高分辨率遥感卫星影像的杆塔倒断检测模型训练方法
CN113924085A (zh) 2019-04-12 2022-01-11 加利福尼亚大学董事会 用于增加肌肉量和氧化代谢的组合物和方法
EP4038222A4 (de) 2019-10-02 2023-10-18 Arizona Board of Regents on behalf of Arizona State University Verfahren und zusammensetzungen zur identifizierung von neoantigenen zur verwendung bei der behandlung und vorbeugung von krebs
US11682189B2 (en) * 2021-07-19 2023-06-20 Microsoft Technology Licensing, Llc Spiral feature search
WO2024028794A1 (en) 2022-08-02 2024-02-08 Temple Therapeutics BV Methods for treating endometrial and ovarian hyperproliferative disorders
WO2025248505A1 (en) 2024-05-31 2025-12-04 Wayne State University Methods for treating endometrial and ovarian hyperproliferative disorders

Family Cites Families (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5925525A (en) 1989-06-07 1999-07-20 Affymetrix, Inc. Method of identifying nucleotide differences
US5143854A (en) 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
US5784162A (en) 1993-08-18 1998-07-21 Applied Spectral Imaging Ltd. Spectral bio-imaging methods for biological research, medical diagnostics and therapy
US6198532B1 (en) * 1991-02-22 2001-03-06 Applied Spectral Imaging Ltd. Spectral bio-imaging of the eye
US5371669A (en) 1992-06-18 1994-12-06 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Sliding mode control method having terminal convergence in finite time
US5371834A (en) 1992-08-28 1994-12-06 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Adaptive neuron model--an architecture for the rapid learning of nonlinear topological transformations
DE4317746A1 (de) 1993-05-27 1994-12-01 Max Planck Gesellschaft Verfahren und Einrichtung zur Raumfilterung
US5858659A (en) 1995-11-29 1999-01-12 Affymetrix, Inc. Polymorphism detection
US6309823B1 (en) 1993-10-26 2001-10-30 Affymetrix, Inc. Arrays of nucleic acid probes for analyzing biotransformation genes and methods of using the same
US5578832A (en) 1994-09-02 1996-11-26 Affymetrix, Inc. Method and apparatus for imaging a sample on a device
US6090555A (en) 1997-12-11 2000-07-18 Affymetrix, Inc. Scanned image alignment systems and methods
US5631734A (en) 1994-02-10 1997-05-20 Affymetrix, Inc. Method and apparatus for detection of fluorescently labeled materials
US5795716A (en) 1994-10-21 1998-08-18 Chee; Mark S. Computer-aided visualization and analysis system for sequence evaluation
US5968740A (en) 1995-07-24 1999-10-19 Affymetrix, Inc. Method of Identifying a Base in a Nucleic Acid
US5733729A (en) 1995-09-14 1998-03-31 Affymetrix, Inc. Computer-aided probability base calling for arrays of nucleic acid probes on chips
US6165734A (en) * 1995-12-12 2000-12-26 Applied Spectral Imaging Ltd. In-situ method of analyzing cells
US6007994A (en) * 1995-12-22 1999-12-28 Yale University Multiparametric fluorescence in situ hybridization
EP0880598A4 (de) 1996-01-23 2005-02-23 Affymetrix Inc Verfahren zur analyse von nukleinsäure
US6361937B1 (en) 1996-03-19 2002-03-26 Affymetrix, Incorporated Computer-aided nucleic acid sequencing
US6391550B1 (en) 1996-09-19 2002-05-21 Affymetrix, Inc. Identification of molecular sequence signatures and methods involving the same
US5812272A (en) * 1997-01-30 1998-09-22 Hewlett-Packard Company Apparatus and method with tiled light source array for integrated assay sensing
ATE319856T1 (de) 1997-06-13 2006-03-15 Affymetrix Inc A Delaware Corp Verfahren zur erkennung von genpolymorphismen und allelexpression unter verwendung von sondenchips
US6420108B2 (en) 1998-02-09 2002-07-16 Affymetrix, Inc. Computer-aided display for comparative gene expression
EP1007737A4 (de) 1997-07-25 2002-07-03 Affymetrix Inc System zur einrichtung einer datenbank für polymorphismen
ATE280246T1 (de) 1997-08-15 2004-11-15 Affymetrix Inc Polymorphismuserkennung mit hilfe cluster-analyse
US6294327B1 (en) 1997-09-08 2001-09-25 Affymetrix, Inc. Apparatus and method for detecting samples labeled with material having strong light scattering properties, using reflection mode light and diffuse scattering
US6013449A (en) 1997-11-26 2000-01-11 The United States Of America As Represented By The Department Of Health And Human Services Probe-based analysis of heterozygous mutations using two-color labelling
US6349144B1 (en) * 1998-02-07 2002-02-19 Biodiscovery, Inc. Automated DNA array segmentation and analysis
BR9909942A (pt) 1998-04-22 2000-12-26 Imaging Res Inc Processos para avaliar ensaios quìmicos e biológicos
US6218122B1 (en) 1998-06-19 2001-04-17 Rosetta Inpharmatics, Inc. Methods of monitoring disease states and therapies using gene expression profiles
US6245507B1 (en) * 1998-08-18 2001-06-12 Orchid Biosciences, Inc. In-line complete hyperspectral fluorescent imaging of nucleic acid molecules
US6185561B1 (en) 1998-09-17 2001-02-06 Affymetrix, Inc. Method and apparatus for providing and expression data mining database
US6453241B1 (en) 1998-12-23 2002-09-17 Rosetta Inpharmatics, Inc. Method and system for analyzing biological response signal data
US6370478B1 (en) 1998-12-28 2002-04-09 Rosetta Inpharmatics, Inc. Methods for drug interaction prediction using biological response profiles
US6245511B1 (en) 1999-02-22 2001-06-12 Vialogy Corp Method and apparatus for exponentially convergent therapy effectiveness monitoring using DNA microarray based viral load measurements
US6142681A (en) 1999-02-22 2000-11-07 Vialogy Corporation Method and apparatus for interpreting hybridized bioelectronic DNA microarray patterns using self-scaling convergent reverberant dynamics
US6136541A (en) 1999-02-22 2000-10-24 Vialogy Corporation Method and apparatus for analyzing hybridized biochip patterns using resonance interactions employing quantum expressor functions
US6225061B1 (en) * 1999-03-10 2001-05-01 Sequenom, Inc. Systems and methods for performing reactions in an unsealed environment
US6171793B1 (en) 1999-04-19 2001-01-09 Affymetrix, Inc. Method for scanning gene probe array to produce data having dynamic range that exceeds that of scanner
US6185581B1 (en) * 1999-08-19 2001-02-06 Sun Microsystems, Inc. Train-algorithm-based garbage collector employing fixed-size remembered sets
EP1089067B1 (de) * 1999-09-29 2004-12-08 Fuji Photo Film Co., Ltd. Vorrichtung zur Erfassung eines Fluoreszenzbildes
US6571005B1 (en) 2000-04-21 2003-05-27 The Regents Of The University Of California Feature extraction and normalization algorithms for high-density oligonucleotide gene expression array data
DE60124598T2 (de) * 2000-06-06 2007-09-06 Agilent Technologies, Inc., Palo Alto Verfahren und System zur Bestimmung der Orientierung eines Microarrays
US20020052882A1 (en) 2000-07-07 2002-05-02 Seth Taylor Method and apparatus for visualizing complex data sets
US6498863B1 (en) * 2000-09-20 2002-12-24 Media Cybernetics Inc. Method, system, and product for analyzing a digitized image of an array to create an image of a grid overlay
US6716629B2 (en) * 2000-10-10 2004-04-06 Biotrove, Inc. Apparatus for assay, synthesis and storage, and methods of manufacture, use, and manipulation thereof
US6542638B2 (en) 2001-02-21 2003-04-01 Shannon Roy Campbell Method for matching spatial patterns
US6490533B2 (en) 2001-04-26 2002-12-03 Affymetrix, Inc. System, method, and product for dynamic noise reduction in scanning of biological materials
US20030071843A1 (en) 2001-10-17 2003-04-17 Bruce Hoff System and method for specifying and applying microarray data preparation
WO2003036225A1 (en) * 2001-10-26 2003-05-01 University Of Rochester Method for biomolecular sensing and system thereof
US6980677B2 (en) * 2002-05-24 2005-12-27 Niles Scientific, Inc. Method, system, and computer code for finding spots defined in biological microarrays

Also Published As

Publication number Publication date
WO2003093810A1 (en) 2003-11-13
EP1502098B1 (de) 2008-09-17
US7466851B2 (en) 2008-12-16
US7006680B2 (en) 2006-02-28
EP1502098A1 (de) 2005-02-02
US20030215867A1 (en) 2003-11-20
AU2003245269A1 (en) 2003-11-17
US20050105787A1 (en) 2005-05-19

Similar Documents

Publication Publication Date Title
DE60323625D1 (de) Verfahren zur charakterisierung der ausgangssignale eines microarrays
DE50305912D1 (de) Verfahren zur zerstörungsfreien prüfung eines bauteils
ATA3292002A (de) Verfahren zur aufnahme eines objektraumes
DE50303605D1 (de) Verfahren zur herstellung eines pressgehärteten bauteils
DE50111955D1 (de) Verfahren zur kleinflächigen beseitigung von lackierungsfehlern
DE60310948D1 (de) Verfahren zur prüfung der integrität von dpfs
DE602004026698D1 (de) Verfahren zur gemeinsmen benutzung von multimedia-daten
DE60330341D1 (de) Verfahren zur herstellung von wabenstrukturen
DE602004022228D1 (de) Befestiger zur beabstandeten Halterung eines Objektes von einem Substrat
DE602004027114D1 (de) Verfahren zur Speicherplattenanordnungsverbindung
DE50309695D1 (de) Verfahren zur regelung der geschwindigkeit eines fahrzeugs
DE602005023270D1 (de) Vorrichtung und verfahren zur modellierung von beziehungen zwischen signalen
DE60318701D1 (de) Verfahren zur verbesserung der effizienz der tierzüchtung
DE60326829D1 (de) Verfahren zur anonymen Authentifizierung eines Datensenders
ATE336597T1 (de) Verfahren zur gewinnung von gold
DE50211235D1 (de) Verfahren zur fixierung eines sensormittels
DE50305566D1 (de) Verfahren zur rundum-bearbeitung eines rohlings
DE60320887D1 (de) Verfahren zur Reflektanzerfassung
DE60211463D1 (de) Verfahren zur Vorbereitung eines Fügesubstrats
DE60301283D1 (de) Verfahren zur Bestimmung von Biopolymeren
DE50301044D1 (de) Verfahren zur auswahl von transpondern
DE60214967D1 (de) Verfahren zur Kontrastverbesserung eines Bildes
EP1468098A4 (de) Verfahren zur hemmung der pathogenität infektiöser substanzen
ATA612002A (de) Verfahren zur aufnahme eines objektraumes
DE602004015009D1 (de) Verfahren zur Hestellung eines Tetraalkyloniumperfluoralkylsulfonats

Legal Events

Date Code Title Description
8364 No opposition during term of opposition