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DE60321053D1 - Matrizenfixierte peptidmimetika als medikamente gegen hiv und krebs - Google Patents

Matrizenfixierte peptidmimetika als medikamente gegen hiv und krebs

Info

Publication number
DE60321053D1
DE60321053D1 DE60321053T DE60321053T DE60321053D1 DE 60321053 D1 DE60321053 D1 DE 60321053D1 DE 60321053 T DE60321053 T DE 60321053T DE 60321053 T DE60321053 T DE 60321053T DE 60321053 D1 DE60321053 D1 DE 60321053D1
Authority
DE
Germany
Prior art keywords
matric
cancer
against hiv
peptide mimetics
fixed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60321053T
Other languages
English (en)
Inventor
Juerg Zumbrunn
J Steven Demarco
Sergio Lociuro
Jan Wim Vrijbloed
Frank Gombert
Reshmi Mukherjee
Kerstin Moehle
Daniel Obrecht
John Anthony Robinson
Barbara Romagnoli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zurich Universitaet Institut fuer Medizinische Virologie
Spexis AG
Original Assignee
Polyphor AG
Zurich Universitaet Institut fuer Medizinische Virologie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Polyphor AG, Zurich Universitaet Institut fuer Medizinische Virologie filed Critical Polyphor AG
Application granted granted Critical
Publication of DE60321053D1 publication Critical patent/DE60321053D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE60321053T 2003-05-02 2003-05-02 Matrizenfixierte peptidmimetika als medikamente gegen hiv und krebs Expired - Lifetime DE60321053D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2003/004641 WO2004096838A1 (en) 2003-05-02 2003-05-02 Template-fixed peptidomimetics as medicaments against hiv and cancer

Publications (1)

Publication Number Publication Date
DE60321053D1 true DE60321053D1 (de) 2008-06-26

Family

ID=33395701

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60321053T Expired - Lifetime DE60321053D1 (de) 2003-05-02 2003-05-02 Matrizenfixierte peptidmimetika als medikamente gegen hiv und krebs

Country Status (7)

Country Link
US (1) US7838496B2 (de)
EP (1) EP1622930B9 (de)
AT (1) ATE395355T1 (de)
AU (1) AU2003232254A1 (de)
DE (1) DE60321053D1 (de)
ES (1) ES2306924T3 (de)
WO (1) WO2004096838A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1773348A4 (de) * 2004-07-12 2009-05-20 Idun Pharmaceuticals Inc Tetrapeptid-analoga
CN105111280B (zh) * 2005-02-17 2020-01-24 波利弗尔有限公司 具有蛋白酶抑制活性的模板固定的β-发夹肽模拟物
CN101142228A (zh) * 2005-02-17 2008-03-12 波利弗尔有限公司 具有蛋白酶抑制活性的模板固定的β-发夹肽模拟物
DK1942108T3 (da) 2005-10-28 2013-12-09 Ono Pharmaceutical Co Forbindelse indeholdende basisk gruppe samt anvendelse deraf
ES2407115T3 (es) 2005-11-18 2013-06-11 Ono Pharmaceutical Co., Ltd. Compuesto que contiene un grupo básico y uso del mismo
WO2007079597A1 (en) * 2006-01-16 2007-07-19 Polyphor Ltd. Template - fixed peptidomimetics with antimicrobial activity
US8580746B2 (en) * 2006-03-30 2013-11-12 Palatin Technologies, Inc. Amide linkage cyclic natriuretic peptide constructs
US7964181B2 (en) * 2006-03-30 2011-06-21 Palatin Technologies, Inc. Amino acid surrogates for peptidic constructs
US8114844B2 (en) * 2006-03-30 2012-02-14 Palatin Technologies, Inc. Linear and cyclic melanocortin receptor-specific peptidomimetics
US8633163B2 (en) * 2007-01-29 2014-01-21 Polyphor Ltd. Template-fixed peptidomimetics
US8399611B2 (en) 2007-02-28 2013-03-19 Polyphor Ltd. Template-fixed peptidomimetics
US8084862B2 (en) 2007-09-20 2011-12-27 International Business Machines Corporation Interconnect structures with patternable low-k dielectrics and method of fabricating same
US7709370B2 (en) 2007-09-20 2010-05-04 International Business Machines Corporation Spin-on antireflective coating for integration of patternable dielectric materials and interconnect structures
US8618663B2 (en) 2007-09-20 2013-12-31 International Business Machines Corporation Patternable dielectric film structure with improved lithography and method of fabricating same
WO2011060832A1 (en) * 2009-11-20 2011-05-26 Polyphor Ag Template-fixed peptidomimetics with ccr10 antagonistic activity
CA2979224A1 (en) * 2015-03-11 2016-09-15 Lumos Pharma, Inc. Synthesis of cyclocreatine and analogs thereof
JP2015155430A (ja) * 2015-04-02 2015-08-27 ポリフォー・アクチェンゲゼルシャフトＰｏｌｙｐｈｏｒ Ａｇ コンホメーションを固定された、合成マクロ環化合物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5856699A (en) 1999-08-30 2001-03-26 Polyphor Ag Synthesis of template-fixed beta-hairpin loop mimetics
CA2439178C (en) * 2001-02-23 2013-06-04 Polyphor Ltd. Template-fixed peptidomimetics with antimicrobial activity
CN101157924A (zh) 2001-12-11 2008-04-09 人体基因组科学有限公司 嗜中性白细胞因子α

Also Published As

Publication number Publication date
AU2003232254A1 (en) 2004-11-23
ATE395355T1 (de) 2008-05-15
EP1622930B1 (de) 2008-05-14
ES2306924T3 (es) 2008-11-16
EP1622930B9 (de) 2009-10-14
WO2004096838A1 (en) 2004-11-11
US20060234923A1 (en) 2006-10-19
US7838496B2 (en) 2010-11-23
AU2003232254A8 (en) 2004-11-23
EP1622930A1 (de) 2006-02-08

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