DE60318182D1 - Aerosol-formulierungen mit estern von 3,17-dihydroxyöstratrien-derivaten zur pulmonalen abgabe - Google Patents
Aerosol-formulierungen mit estern von 3,17-dihydroxyöstratrien-derivaten zur pulmonalen abgabeInfo
- Publication number
- DE60318182D1 DE60318182D1 DE60318182T DE60318182T DE60318182D1 DE 60318182 D1 DE60318182 D1 DE 60318182D1 DE 60318182 T DE60318182 T DE 60318182T DE 60318182 T DE60318182 T DE 60318182T DE 60318182 D1 DE60318182 D1 DE 60318182D1
- Authority
- DE
- Germany
- Prior art keywords
- dihydroxy
- esters
- pulmonary delivery
- aerosol formulations
- estratriene derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000203 mixture Substances 0.000 title abstract 2
- VOXZDWNPVJITMN-SFFUCWETSA-N 17α-estradiol Chemical class OC1=CC=C2[C@H]3CC[C@](C)([C@@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 VOXZDWNPVJITMN-SFFUCWETSA-N 0.000 title 1
- 239000000443 aerosol Substances 0.000 title 1
- 230000002685 pulmonary effect Effects 0.000 title 1
- 206010019233 Headaches Diseases 0.000 abstract 1
- 206010027304 Menopausal symptoms Diseases 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 231100000869 headache Toxicity 0.000 abstract 1
- 206010027599 migraine Diseases 0.000 abstract 1
- 239000003380 propellant Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Otolaryngology (AREA)
- Pulmonology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Endocrinology (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Steroid Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP02004787 | 2002-03-01 | ||
| EP02004787A EP1340503A1 (de) | 2002-03-01 | 2002-03-01 | Lösung Aerosol Formulierung von Estern von 3,17-dihydroxy Oestratrien-Derivaten zur Lungenverabreichung |
| PCT/EP2003/001856 WO2003074058A1 (en) | 2002-03-01 | 2003-02-24 | Aerosol formulations containing esters of 3,17-dihydroxy oestratriene derivatives for pulmonary delivery |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60318182D1 true DE60318182D1 (de) | 2008-01-31 |
| DE60318182T2 DE60318182T2 (de) | 2008-12-04 |
Family
ID=27675680
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60318182T Expired - Lifetime DE60318182T2 (de) | 2002-03-01 | 2003-02-24 | Aerosol-formulierungen mit estern von 3,17-dihydroxyöstratrien-derivaten zur pulmonalen abgabe |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20050209207A1 (de) |
| EP (2) | EP1340503A1 (de) |
| AT (1) | ATE381339T1 (de) |
| AU (1) | AU2003215588A1 (de) |
| BR (1) | BR0303347A (de) |
| DE (1) | DE60318182T2 (de) |
| ES (1) | ES2297183T3 (de) |
| NO (1) | NO20034873L (de) |
| WO (1) | WO2003074058A1 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUP1100723A2 (en) * | 2011-12-28 | 2013-06-28 | Avidin Kft | Use of estrogen derivatives for preparing medicament for the treatment of psychiatric diseases |
| WO2025039045A1 (en) * | 2023-08-23 | 2025-02-27 | Inhaler Supplies Pty Ltd | Inhalable formulation for volatile actives |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1099722A (en) * | 1964-04-20 | 1968-01-17 | Takeda Chemical Industries Ltd | Aerosol |
| DE2758549A1 (de) * | 1977-12-23 | 1979-07-05 | Schering Ag | Pharmazeutische zubereitung |
| US4315925A (en) * | 1980-05-30 | 1982-02-16 | University Of Kentucky Research Foundation | Method of administering natural female sex hormones |
| US5043331A (en) * | 1989-06-15 | 1991-08-27 | Orion-Yhtyma Oy | Treatment of postmenopausal disorders |
| AU658854B2 (en) * | 1990-10-18 | 1995-05-04 | Minnesota Mining And Manufacturing Company | Aerosol formulation comprising beclomethasone 17,21 dipropionate |
| US6461591B1 (en) * | 1997-02-05 | 2002-10-08 | Jago Research Ag | Medical aerosol formulations |
| US6126919A (en) * | 1997-02-07 | 2000-10-03 | 3M Innovative Properties Company | Biocompatible compounds for pharmaceutical drug delivery systems |
| GB2326334A (en) * | 1997-06-13 | 1998-12-23 | Chiesi Farma Spa | Pharmaceutical aerosol compositions |
| US20010031244A1 (en) * | 1997-06-13 | 2001-10-18 | Chiesi Farmaceutici S.P.A. | Pharmaceutical aerosol composition |
| EP1027057A4 (de) * | 1997-10-28 | 2003-01-02 | Vivus Inc | Behandlung von weibliche sexuelle störungen |
| IT1303788B1 (it) * | 1998-11-25 | 2001-02-23 | Chiesi Farma Spa | Formulazioni di aerosol medicinali. |
| US6117446A (en) * | 1999-01-26 | 2000-09-12 | Place; Virgil A. | Drug dosage unit for buccal administration of steroidal active agents |
-
2002
- 2002-03-01 EP EP02004787A patent/EP1340503A1/de not_active Withdrawn
-
2003
- 2003-02-24 US US10/504,841 patent/US20050209207A1/en not_active Abandoned
- 2003-02-24 EP EP03743324A patent/EP1480651B1/de not_active Expired - Lifetime
- 2003-02-24 WO PCT/EP2003/001856 patent/WO2003074058A1/en not_active Ceased
- 2003-02-24 AU AU2003215588A patent/AU2003215588A1/en not_active Abandoned
- 2003-02-24 BR BR0303347-3A patent/BR0303347A/pt not_active IP Right Cessation
- 2003-02-24 DE DE60318182T patent/DE60318182T2/de not_active Expired - Lifetime
- 2003-02-24 AT AT03743324T patent/ATE381339T1/de active
- 2003-02-24 ES ES03743324T patent/ES2297183T3/es not_active Expired - Lifetime
- 2003-10-31 NO NO20034873A patent/NO20034873L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1480651B1 (de) | 2007-12-19 |
| AU2003215588A1 (en) | 2003-09-16 |
| ATE381339T1 (de) | 2008-01-15 |
| BR0303347A (pt) | 2004-07-13 |
| NO20034873L (no) | 2003-12-23 |
| EP1340503A1 (de) | 2003-09-03 |
| NO20034873D0 (no) | 2003-10-31 |
| WO2003074058A1 (en) | 2003-09-12 |
| EP1480651A1 (de) | 2004-12-01 |
| DE60318182T2 (de) | 2008-12-04 |
| ES2297183T3 (es) | 2008-05-01 |
| US20050209207A1 (en) | 2005-09-22 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JO2381B1 (en) | Formulation containing anticholinergic drug for the treatment of chronic obstructive pulmonary disease | |
| CY1122851T1 (el) | Υπερλεπτο σκευασμα φορμοτερολης | |
| DK1389137T3 (da) | Sammensætninger til lungelægemiddellevering af protein | |
| DK0616525T3 (da) | Medikamenter | |
| SE0102276D0 (sv) | Device and method for the administration of a medicament | |
| CO4940408A1 (es) | Composicion de aerosol farmaceutico | |
| PT918507E (pt) | Formulacoes em aerossol | |
| ES2176355T3 (es) | Formulaciones de aerosol de peptidos y proteinas. | |
| GB9425160D0 (en) | Medicaments | |
| ATE544447T1 (de) | Arzneistoffcoating mit hohem wirkstoffanteil sowie methoden zu dessen herstellung | |
| YU2494A (sh) | Farmaceutska formulacija za tretiranje zavisnosti od nikotina | |
| ATE395071T1 (de) | Pharmazeutische zubereitungen zur angiogenese- therapie | |
| MXPA05003253A (es) | Nuevos derivados de pirimidinamida y el uso de los mismos. | |
| GB0323684D0 (en) | Improvements in or relating to organic compounds | |
| ES2134634T3 (es) | Composiciones farmaceuticas y dispositivos para su administracion. | |
| NO20083759L (no) | Doserings aerosoler for administrering av farmasoytiske preparater | |
| BG107257A (en) | Formulations containing a glucocorticoid drug for the treatment of bronchopulmonary diseases | |
| ATE381339T1 (de) | Aerosol-formulierungen mit estern von 3,17- dihydroxyöstratrien-derivaten zur pulmonalen abgabe | |
| NO20054034L (no) | Fremgangsmate for behandling av hypotyroidisme. | |
| ATE286716T1 (de) | Pharmazeutische formulierungen enthaltend salmeterol | |
| ECSP971997A (es) | Nueva formulacion de un producto farmaceutico |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |