DE60315666D1 - Furopyridin- und furopyrimidinderivate zur behandlung von hyperproliferativen erkrankungen - Google Patents
Furopyridin- und furopyrimidinderivate zur behandlung von hyperproliferativen erkrankungenInfo
- Publication number
- DE60315666D1 DE60315666D1 DE60315666T DE60315666T DE60315666D1 DE 60315666 D1 DE60315666 D1 DE 60315666D1 DE 60315666 T DE60315666 T DE 60315666T DE 60315666 T DE60315666 T DE 60315666T DE 60315666 D1 DE60315666 D1 DE 60315666D1
- Authority
- DE
- Germany
- Prior art keywords
- furopyridine
- hyperproliferative
- illnesses
- treatment
- furopyrimidine derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- YRTCKZIKGWZNCU-UHFFFAOYSA-N furo[3,2-b]pyridine Chemical compound C1=CC=C2OC=CC2=N1 YRTCKZIKGWZNCU-UHFFFAOYSA-N 0.000 title 1
- JUQAECQBUNODQP-UHFFFAOYSA-N furo[3,2-d]pyrimidine Chemical class C1=NC=C2OC=CC2=N1 JUQAECQBUNODQP-UHFFFAOYSA-N 0.000 title 1
- 230000003463 hyperproliferative effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39506502P | 2002-07-11 | 2002-07-11 | |
| US395065P | 2002-07-11 | ||
| PCT/US2003/021688 WO2004007502A1 (en) | 2002-07-11 | 2003-07-11 | Furopyridine and furopyrimidine derivatives for the treatment of hyper-proliferative disorders |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60315666D1 true DE60315666D1 (de) | 2007-09-27 |
| DE60315666T2 DE60315666T2 (de) | 2008-05-08 |
Family
ID=30115806
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60315666T Expired - Fee Related DE60315666T2 (de) | 2002-07-11 | 2003-07-11 | Furopyridin- und furopyrimidinderivate zur behandlung von hyperproliferativen erkrankungen |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US7429584B2 (de) |
| EP (1) | EP1534715B1 (de) |
| JP (1) | JP2005533109A (de) |
| AU (1) | AU2003256491A1 (de) |
| CA (1) | CA2491077A1 (de) |
| DE (1) | DE60315666T2 (de) |
| ES (1) | ES2291690T3 (de) |
| WO (1) | WO2004007502A1 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101061101B (zh) * | 2003-12-22 | 2011-09-07 | 巴斯利尔药物股份公司 | 芳酰基呋喃和芳酰基噻吩 |
| WO2005087778A1 (en) * | 2004-02-16 | 2005-09-22 | Bayer Pharmaceuticals Corporation | Tricyclic furopyridine derivatives useful in the treatment of hyper-proliferative disorders |
| US7674907B2 (en) * | 2004-07-23 | 2010-03-09 | Amgen Inc. | Furanopyridine derivatives and methods of use |
| CN112608327B (zh) * | 2021-01-28 | 2021-11-02 | 河南大学 | 呋喃并喹啉衍生物、其制备方法及应用 |
| CN117003760B (zh) * | 2023-07-07 | 2025-10-03 | 广东工业大学 | 一种喹啉稠环衍生物的制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE107287C (de) * | ||||
| DD107287A1 (de) * | 1973-08-01 | 1974-07-20 | ||
| US5137879A (en) * | 1990-03-30 | 1992-08-11 | Dowelanco | Furopyrimidin-4-imine derivatives |
| DK0682027T3 (da) | 1994-05-03 | 1998-05-04 | Ciba Geigy Ag | Pyrrolopyrimidinderivater med antiproliferativ virkning |
| GB9915437D0 (en) * | 1999-07-01 | 1999-09-01 | Cerebrus Ltd | Chemical compounds III |
-
2003
- 2003-07-11 ES ES03764486T patent/ES2291690T3/es not_active Expired - Lifetime
- 2003-07-11 DE DE60315666T patent/DE60315666T2/de not_active Expired - Fee Related
- 2003-07-11 WO PCT/US2003/021688 patent/WO2004007502A1/en not_active Ceased
- 2003-07-11 JP JP2004521663A patent/JP2005533109A/ja active Pending
- 2003-07-11 US US10/515,605 patent/US7429584B2/en not_active Expired - Fee Related
- 2003-07-11 CA CA002491077A patent/CA2491077A1/en not_active Abandoned
- 2003-07-11 AU AU2003256491A patent/AU2003256491A1/en not_active Abandoned
- 2003-07-11 EP EP03764486A patent/EP1534715B1/de not_active Expired - Lifetime
-
2008
- 2008-09-26 US US12/239,279 patent/US20090143412A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003256491A1 (en) | 2004-02-02 |
| US20090143412A1 (en) | 2009-06-04 |
| EP1534715A1 (de) | 2005-06-01 |
| JP2005533109A (ja) | 2005-11-04 |
| DE60315666T2 (de) | 2008-05-08 |
| CA2491077A1 (en) | 2004-01-22 |
| EP1534715B1 (de) | 2007-08-15 |
| US20060040960A1 (en) | 2006-02-23 |
| US7429584B2 (en) | 2008-09-30 |
| WO2004007502A1 (en) | 2004-01-22 |
| ES2291690T3 (es) | 2008-03-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |