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DE60313804D1 - Alfa-glycosidase inhibitoren und deren synthese aus einer natürlichen quelle - Google Patents

Alfa-glycosidase inhibitoren und deren synthese aus einer natürlichen quelle

Info

Publication number
DE60313804D1
DE60313804D1 DE60313804T DE60313804T DE60313804D1 DE 60313804 D1 DE60313804 D1 DE 60313804D1 DE 60313804 T DE60313804 T DE 60313804T DE 60313804 T DE60313804 T DE 60313804T DE 60313804 D1 DE60313804 D1 DE 60313804D1
Authority
DE
Germany
Prior art keywords
alfa
synthesis
natural source
glycosidase inhibitors
glycosidase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60313804T
Other languages
English (en)
Other versions
DE60313804T2 (de
Inventor
Janaswamy Madhusudana Rao
Rao Jagadeeshwar Rao
Upparapalli Sampath Kumar
Singireddy Venkat Reddy
Ashok Kumar Tiwari
Jhillusingh Yadav
Kondapuram Vijaya Raghavan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Council of Scientific and Industrial Research CSIR
Original Assignee
Council of Scientific and Industrial Research CSIR
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Council of Scientific and Industrial Research CSIR filed Critical Council of Scientific and Industrial Research CSIR
Application granted granted Critical
Publication of DE60313804D1 publication Critical patent/DE60313804D1/de
Publication of DE60313804T2 publication Critical patent/DE60313804T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/60—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2
    • C07D311/62—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2 with oxygen atoms directly attached in position 3, e.g. anthocyanidins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Communicable Diseases (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
DE60313804T 2002-12-17 2003-03-30 Neue Alpha-Glucosidaseinhibitoren und deren Synthese aus einer natürlichen Quelle Expired - Lifetime DE60313804T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PCT/IB2002/005426 WO2004054993A1 (en) 2002-12-17 2002-12-17 A new antioxidant from natural source
WOPCT/IB02/05426 2002-12-17
PCT/IB2003/001157 WO2004054995A1 (en) 2002-12-17 2003-03-30 New alpha-glucosidase inhibitors and their synthesis from a natural source

Publications (2)

Publication Number Publication Date
DE60313804D1 true DE60313804D1 (de) 2007-06-21
DE60313804T2 DE60313804T2 (de) 2008-01-24

Family

ID=32587401

Family Applications (2)

Application Number Title Priority Date Filing Date
DE60216332T Expired - Lifetime DE60216332T2 (de) 2002-12-17 2002-12-17 Antioxydationsmittel aus natürlicher quelle
DE60313804T Expired - Lifetime DE60313804T2 (de) 2002-12-17 2003-03-30 Neue Alpha-Glucosidaseinhibitoren und deren Synthese aus einer natürlichen Quelle

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE60216332T Expired - Lifetime DE60216332T2 (de) 2002-12-17 2002-12-17 Antioxydationsmittel aus natürlicher quelle

Country Status (6)

Country Link
US (1) US6781002B2 (de)
EP (2) EP1572673B1 (de)
JP (2) JP2006514947A (de)
AU (2) AU2002348822A1 (de)
DE (2) DE60216332T2 (de)
WO (2) WO2004054993A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004054993A1 (en) * 2002-12-17 2004-07-01 Council Of Scientific And Industrial Research A new antioxidant from natural source
JP2008133192A (ja) * 2005-09-29 2008-06-12 Kureha Corp 抗糖尿病剤
JP5716205B2 (ja) * 2011-03-29 2015-05-13 学校法人日本大学 グルコシダーゼ活性阻害用組成物及びそのスクリーニング方法
EP3125912B1 (de) * 2014-03-19 2019-05-29 Stellenbosch University Verfahren zur behandlung oder verbesserung muskelgewebe
CN104873908A (zh) * 2015-06-13 2015-09-02 济南邦文医药科技有限公司 一种治疗冠心病伴焦虑的中药

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6207842B1 (en) * 1997-10-09 2001-03-27 Mars Incorporated Process for preparing procyanidin(4-6 or 4-8) oligomers and their derivatives
WO2004054993A1 (en) * 2002-12-17 2004-07-01 Council Of Scientific And Industrial Research A new antioxidant from natural source

Also Published As

Publication number Publication date
DE60313804T2 (de) 2008-01-24
AU2002348822A1 (en) 2004-07-09
DE60216332T2 (de) 2007-07-05
US6781002B2 (en) 2004-08-24
EP1572675B1 (de) 2007-05-09
US20040116716A1 (en) 2004-06-17
JP2006514947A (ja) 2006-05-18
AU2003212593A1 (en) 2004-07-09
DE60216332D1 (de) 2007-01-04
WO2004054995A1 (en) 2004-07-01
EP1572675A1 (de) 2005-09-14
EP1572673A1 (de) 2005-09-14
EP1572673B1 (de) 2006-11-22
WO2004054993A1 (en) 2004-07-01
JP2006513178A (ja) 2006-04-20

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Legal Events

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