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DE60309700D1 - Verfahren und vorrichtung zur verringerung von artefakten in massenspektrometern - Google Patents

Verfahren und vorrichtung zur verringerung von artefakten in massenspektrometern

Info

Publication number
DE60309700D1
DE60309700D1 DE60309700T DE60309700T DE60309700D1 DE 60309700 D1 DE60309700 D1 DE 60309700D1 DE 60309700 T DE60309700 T DE 60309700T DE 60309700 T DE60309700 T DE 60309700T DE 60309700 D1 DE60309700 D1 DE 60309700D1
Authority
DE
Germany
Prior art keywords
ions
trap
approach involves
voltage gradients
barriers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60309700T
Other languages
English (en)
Other versions
DE60309700T2 (de
Inventor
Frank Londry
R Stott
A Collings
James Hager
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nordion Inc
Original Assignee
MDS Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MDS Inc filed Critical MDS Inc
Application granted granted Critical
Publication of DE60309700D1 publication Critical patent/DE60309700D1/de
Publication of DE60309700T2 publication Critical patent/DE60309700T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H01J49/34—Dynamic spectrometers
    • H01J49/42—Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
    • H01J49/4205—Device types
    • H01J49/422—Two-dimensional RF ion traps
    • H01J49/4225—Multipole linear ion traps, e.g. quadrupoles, hexapoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Electron Tubes For Measurement (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
DE60309700T 2002-05-30 2003-05-29 Verfahren und vorrichtung zur verringerung von artefakten in massenspektrometern Expired - Lifetime DE60309700T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US38465502P 2002-05-30 2002-05-30
US384655P 2002-05-30
PCT/CA2003/000803 WO2003102517A2 (en) 2002-05-30 2003-05-29 Methods and apparatus for reducing artifacts in mass spectrometers

Publications (2)

Publication Number Publication Date
DE60309700D1 true DE60309700D1 (de) 2006-12-28
DE60309700T2 DE60309700T2 (de) 2007-09-13

Family

ID=29712074

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60309700T Expired - Lifetime DE60309700T2 (de) 2002-05-30 2003-05-29 Verfahren und vorrichtung zur verringerung von artefakten in massenspektrometern

Country Status (8)

Country Link
US (1) US6909089B2 (de)
EP (1) EP1508156B1 (de)
JP (1) JP4342436B2 (de)
AT (1) ATE345578T1 (de)
AU (1) AU2003229212A1 (de)
CA (1) CA2485894C (de)
DE (1) DE60309700T2 (de)
WO (1) WO2003102517A2 (de)

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US6933498B1 (en) * 2004-03-16 2005-08-23 Ut-Battelle, Llc Ion trap array-based systems and methods for chemical analysis
JP4643206B2 (ja) * 2004-09-03 2011-03-02 株式会社日立ハイテクノロジーズ 質量分析装置
US7064322B2 (en) 2004-10-01 2006-06-20 Agilent Technologies, Inc. Mass spectrometer multipole device
CA2621758C (en) * 2005-01-17 2014-12-23 Micromass Uk Limited Mass spectrometer
US7067802B1 (en) * 2005-02-11 2006-06-27 Thermo Finnigan Llc Generation of combination of RF and axial DC electric fields in an RF-only multipole
GB2427067B (en) * 2005-03-29 2010-02-24 Thermo Finnigan Llc Improvements relating to ion trapping
CA2608972A1 (en) * 2005-05-18 2006-11-23 Mds Inc. Doing Business As Mds Sciex Method and apparatus for mass selective axial transport using quadrupolar dc
US7323683B2 (en) 2005-08-31 2008-01-29 The Rockefeller University Linear ion trap for mass spectrometry
US7557343B2 (en) * 2005-09-13 2009-07-07 Agilent Technologies, Inc. Segmented rod multipole as ion processing cell
US7385185B2 (en) * 2005-12-20 2008-06-10 Agilent Technologies, Inc. Molecular activation for tandem mass spectroscopy
US7378653B2 (en) * 2006-01-10 2008-05-27 Varian, Inc. Increasing ion kinetic energy along axis of linear ion processing devices
US7541575B2 (en) * 2006-01-11 2009-06-02 Mds Inc. Fragmenting ions in mass spectrometry
DK2029778T3 (en) 2006-06-14 2018-08-20 Verinata Health Inc DIAGNOSIS OF Fetal ABNORMITIES
US7759637B2 (en) * 2006-06-30 2010-07-20 Dh Technologies Development Pte. Ltd Method for storing and reacting ions in a mass spectrometer
JP5180217B2 (ja) * 2006-09-28 2013-04-10 ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド 多重極質量分析計において補助電極を用いた軸方向の放出およびイントラップフラグメント化の方法
JP4918846B2 (ja) * 2006-11-22 2012-04-18 株式会社日立製作所 質量分析装置及び質量分析方法
GB0626025D0 (en) 2006-12-29 2007-02-07 Thermo Electron Bremen Gmbh Ion trap
JP2010521681A (ja) * 2007-03-23 2010-06-24 エムディーエス アナリティカル テクノロジーズ， ア ビジネス ユニット オブ エムディーエス インコーポレイテッド， ドゥーイング ビジネス スルー イッツ サイエックス ディビジョン イオントラップ質量分析計システムを操作するための方法
US7868289B2 (en) * 2007-04-30 2011-01-11 Ionics Mass Spectrometry Group Inc. Mass spectrometer ion guide providing axial field, and method
US7847240B2 (en) * 2007-06-11 2010-12-07 Dana-Farber Cancer Institute, Inc. Mass spectroscopy system and method including an excitation gate
GB0713590D0 (en) 2007-07-12 2007-08-22 Micromass Ltd Mass spectrometer
JP5341323B2 (ja) * 2007-07-17 2013-11-13 株式会社日立ハイテクノロジーズ 質量分析装置
US7847248B2 (en) * 2007-12-28 2010-12-07 Mds Analytical Technologies, A Business Unit Of Mds Inc. Method and apparatus for reducing space charge in an ion trap
US20090194679A1 (en) * 2008-01-31 2009-08-06 Agilent Technologies, Inc. Methods and apparatus for reducing noise in mass spectrometry
US7675031B2 (en) * 2008-05-29 2010-03-09 Thermo Finnigan Llc Auxiliary drag field electrodes
GB0816258D0 (en) * 2008-09-05 2008-10-15 Ulive Entpr Ltd Process
US20110248157A1 (en) * 2008-10-14 2011-10-13 Masuyuki Sugiyama Mass spectrometer and mass spectrometry method
CN102231356B (zh) * 2009-12-01 2015-03-11 株式会社岛津制作所 线形离子阱分析器
US8829434B2 (en) * 2010-11-19 2014-09-09 Hitachi High-Technologies Corporation Mass spectrometer and mass spectrometry method
US8759759B2 (en) * 2011-04-04 2014-06-24 Shimadzu Corporation Linear ion trap analyzer
WO2013008086A2 (en) * 2011-07-11 2013-01-17 Dh Technologies Development Pte. Ltd. Method to control space charge in a mass spectrometer
GB2497799B (en) 2011-12-21 2016-06-22 Thermo Fisher Scient (Bremen) Gmbh Collision cell multipole
EP2798666B1 (de) 2011-12-29 2018-07-04 DH Technologies Development Pte. Ltd. Ionenextraktionsverfahren für ionenfallen-massenspektrometrie
WO2015092399A1 (en) 2013-12-19 2015-06-25 Micromass Uk Limited High pressure mass resolving ion guide with axial field
GB201322515D0 (en) * 2013-12-19 2014-02-05 Micromass Ltd High pressure mass resolving ion guide with axial field
US9870911B2 (en) * 2013-12-23 2018-01-16 Dh Technologies Development Pte. Ltd. Method and apparatus for processing ions
US9613788B2 (en) 2014-06-13 2017-04-04 Perkinelmer Health Sciences, Inc. RF ion guide with axial fields
GB2541346B (en) 2014-06-25 2022-05-11 Hitachi High Tech Corp Mass spectrometer
EP4567860A3 (de) * 2014-11-28 2025-08-06 DH Technologies Development Pte. Ltd. Rf-ionenführung
US10147595B2 (en) * 2016-12-19 2018-12-04 Agilent Technologies, Inc. Quadrupole rod assembly
US11728153B2 (en) * 2018-12-14 2023-08-15 Thermo Finnigan Llc Collision cell with enhanced ion beam focusing and transmission
US11443933B1 (en) * 2020-10-30 2022-09-13 Agilent Technologies, Inc. Inductively coupled plasma mass spectrometry (ICP-MS) with ion trapping
CN116868306A (zh) * 2021-01-25 2023-10-10 Dh科技发展私人贸易有限公司 质谱仪的真空腔室中的压强控制
GB2631594B (en) * 2023-06-28 2025-08-06 Bruker Daltonics Gmbh & Co Kg Differential trapped ion mobility separator

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US4861988A (en) * 1987-09-30 1989-08-29 Cornell Research Foundation, Inc. Ion spray apparatus and method
CA1307859C (en) * 1988-12-12 1992-09-22 Donald James Douglas Mass spectrometer and method with improved ion transmission
US5248875A (en) * 1992-04-24 1993-09-28 Mds Health Group Limited Method for increased resolution in tandem mass spectrometry
US5420425A (en) * 1994-05-27 1995-05-30 Finnigan Corporation Ion trap mass spectrometer system and method
JPH11510946A (ja) * 1995-08-11 1999-09-21 エムディーエス ヘルス グループ リミテッド 軸電界を有する分光計
US5576540A (en) * 1995-08-11 1996-11-19 Mds Health Group Limited Mass spectrometer with radial ejection
US6177668B1 (en) * 1996-06-06 2001-01-23 Mds Inc. Axial ejection in a multipole mass spectrometer
US6504148B1 (en) * 1999-05-27 2003-01-07 Mds Inc. Quadrupole mass spectrometer with ION traps to enhance sensitivity
US7041967B2 (en) * 2001-05-25 2006-05-09 Mds Inc. Method of mass spectrometry, to enhance separation of ions with different charges
CA2391140C (en) * 2001-06-25 2008-10-07 Micromass Limited Mass spectrometer

Also Published As

Publication number Publication date
CA2485894C (en) 2012-10-30
AU2003229212A1 (en) 2003-12-19
DE60309700T2 (de) 2007-09-13
EP1508156B1 (de) 2006-11-15
CA2485894A1 (en) 2003-12-11
WO2003102517A3 (en) 2004-04-15
JP2005528745A (ja) 2005-09-22
ATE345578T1 (de) 2006-12-15
JP4342436B2 (ja) 2009-10-14
AU2003229212A8 (en) 2003-12-19
US20040011956A1 (en) 2004-01-22
WO2003102517A2 (en) 2003-12-11
EP1508156A2 (de) 2005-02-23
US6909089B2 (en) 2005-06-21

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