DE60308450D1 - S-Omeprazol-Magnesiumsalz - Google Patents
S-Omeprazol-MagnesiumsalzInfo
- Publication number
- DE60308450D1 DE60308450D1 DE60308450T DE60308450T DE60308450D1 DE 60308450 D1 DE60308450 D1 DE 60308450D1 DE 60308450 T DE60308450 T DE 60308450T DE 60308450 T DE60308450 T DE 60308450T DE 60308450 D1 DE60308450 D1 DE 60308450D1
- Authority
- DE
- Germany
- Prior art keywords
- magnesium salt
- omeprazole
- omeprazole magnesium
- enantiomer
- solvent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- SUBDBMMJDZJVOS-UHFFFAOYSA-N 5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole Chemical compound N=1C2=CC(OC)=CC=C2NC=1S(=O)CC1=NC=C(C)C(OC)=C1C SUBDBMMJDZJVOS-UHFFFAOYSA-N 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- 229910052749 magnesium Inorganic materials 0.000 abstract 2
- 239000011777 magnesium Substances 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 229960000381 omeprazole Drugs 0.000 abstract 2
- 239000002904 solvent Substances 0.000 abstract 2
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 abstract 1
- 238000001704 evaporation Methods 0.000 abstract 1
- -1 magnesium alkoxide Chemical class 0.000 abstract 1
- 159000000003 magnesium salts Chemical class 0.000 abstract 1
- 230000007935 neutral effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
- A61K9/2846—Poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
- Vaporization, Distillation, Condensation, Sublimation, And Cold Traps (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA2386716 | 2002-05-17 | ||
| CA2386716A CA2386716C (en) | 2002-05-17 | 2002-05-17 | Magnesium salt of s-omeprazole |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60308450D1 true DE60308450D1 (de) | 2006-11-02 |
| DE60308450T2 DE60308450T2 (de) | 2007-05-10 |
Family
ID=29555354
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60308450T Expired - Lifetime DE60308450T2 (de) | 2002-05-17 | 2003-05-16 | S-Omeprazol-Magnesiumsalz |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1375497B1 (de) |
| JP (1) | JP2004002422A (de) |
| AT (1) | ATE340170T1 (de) |
| CA (1) | CA2386716C (de) |
| DE (1) | DE60308450T2 (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5840737A (en) | 1996-01-04 | 1998-11-24 | The Curators Of The University Of Missouri | Omeprazole solution and method for using same |
| US6489346B1 (en) | 1996-01-04 | 2002-12-03 | The Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and method of using same |
| AU2003262992A1 (en) | 2002-08-30 | 2004-03-19 | Reddy's Laboratories Limited | Amorphous hydrates of esomeprazole magnesium and process for the preparation thereof |
| AU2003278406A1 (en) * | 2002-10-22 | 2004-05-13 | Ranbaxy Laboratories Limited | Amorphous form of esomeprazole salts |
| WO2005082888A1 (en) * | 2004-03-01 | 2005-09-09 | Milen Merkez Ilac Endustrisi A.S. | Process for the preparation of magnesium salt of omeprazole |
| ES2246149B1 (es) * | 2004-07-02 | 2007-06-01 | Esteve Quimica, S.A. | Formas solidas de la sal magnesica de s-omeprazol y procedimientos para su preparacion. |
| EP1801110A1 (de) | 2005-12-22 | 2007-06-27 | KRKA, tovarna zdravil, d.d., Novo mesto | Argininsalz des Esomeprazols |
| EP1947099A1 (de) * | 2007-01-18 | 2008-07-23 | LEK Pharmaceuticals D.D. | Verfahren zur Entfernung von Lösungsmitteln in Omeprazol-Salzen |
| EP2147918A1 (de) | 2008-07-21 | 2010-01-27 | LEK Pharmaceuticals D.D. | Verfahren zur Herstellung von S-Omeprazol-Magnesium in einer stabilen Form |
| CN116102538B (zh) * | 2023-01-29 | 2024-10-18 | 山东省分析测试中心 | 一种转晶制备三水合艾司奥美拉唑镁的方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE8301182D0 (sv) * | 1983-03-04 | 1983-03-04 | Haessle Ab | Novel compounds |
| SE9301830D0 (sv) * | 1993-05-28 | 1993-05-28 | Ab Astra | New compounds |
| SE9302396D0 (sv) * | 1993-07-09 | 1993-07-09 | Ab Astra | A novel compound form |
| CA2290893C (en) * | 1999-11-16 | 2007-05-01 | Bernard Charles Sherman | Magnesium omeprazole |
-
2002
- 2002-05-17 CA CA2386716A patent/CA2386716C/en not_active Expired - Fee Related
-
2003
- 2003-05-16 AT AT03253070T patent/ATE340170T1/de not_active IP Right Cessation
- 2003-05-16 DE DE60308450T patent/DE60308450T2/de not_active Expired - Lifetime
- 2003-05-16 EP EP03253070A patent/EP1375497B1/de not_active Revoked
- 2003-05-19 JP JP2003140745A patent/JP2004002422A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| ATE340170T1 (de) | 2006-10-15 |
| DE60308450T2 (de) | 2007-05-10 |
| EP1375497B1 (de) | 2006-09-20 |
| CA2386716C (en) | 2012-07-24 |
| EP1375497A1 (de) | 2004-01-02 |
| JP2004002422A (ja) | 2004-01-08 |
| CA2386716A1 (en) | 2003-11-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8363 | Opposition against the patent |