DE60306534D1 - Neue derivate von cycloalkanodionen, verfahren zu deren herstellung und deren pharmakologische anwendungen - Google Patents
Neue derivate von cycloalkanodionen, verfahren zu deren herstellung und deren pharmakologische anwendungenInfo
- Publication number
- DE60306534D1 DE60306534D1 DE60306534T DE60306534T DE60306534D1 DE 60306534 D1 DE60306534 D1 DE 60306534D1 DE 60306534 T DE60306534 T DE 60306534T DE 60306534 T DE60306534 T DE 60306534T DE 60306534 D1 DE60306534 D1 DE 60306534D1
- Authority
- DE
- Germany
- Prior art keywords
- cycloalkanodiones
- preparation
- new derivatives
- treatment
- pharmacological applications
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 230000000144 pharmacologic effect Effects 0.000 title 1
- QZAYGJVTTNCVMB-UHFFFAOYSA-N serotonin Chemical compound C1=C(O)C=C2C(CCN)=CNC2=C1 QZAYGJVTTNCVMB-UHFFFAOYSA-N 0.000 abstract 5
- 239000000556 agonist Substances 0.000 abstract 2
- 238000011282 treatment Methods 0.000 abstract 2
- 102100022738 5-hydroxytryptamine receptor 1A Human genes 0.000 abstract 1
- 101710138638 5-hydroxytryptamine receptor 1A Proteins 0.000 abstract 1
- 208000032382 Ischaemic stroke Diseases 0.000 abstract 1
- 208000029028 brain injury Diseases 0.000 abstract 1
- 239000004090 neuroprotective agent Substances 0.000 abstract 1
- 230000001575 pathological effect Effects 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 102000005962 receptors Human genes 0.000 abstract 1
- 108020003175 receptors Proteins 0.000 abstract 1
- 229940076279 serotonin Drugs 0.000 abstract 1
- 230000000472 traumatic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4188—1,3-Diazoles condensed with other heterocyclic ring systems, e.g. biotin, sorbinil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/34—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES200201811A ES2199086B1 (es) | 2002-07-31 | 2002-07-31 | Nuevos derivados de cicloalcanodionas, procedimiento para su preparacion y sus aplicaciones farmacologicas. |
| ES200201811 | 2002-07-31 | ||
| PCT/ES2003/000394 WO2004014915A1 (es) | 2002-07-31 | 2003-07-29 | Nuevos derivados de cicloalcanodionas procedimiento para su preparación y sus aplicaciones farmacológicas |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60306534D1 true DE60306534D1 (de) | 2006-08-10 |
| DE60306534T2 DE60306534T2 (de) | 2007-04-19 |
Family
ID=31198114
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60306534T Expired - Fee Related DE60306534T2 (de) | 2002-07-31 | 2003-07-29 | Neue derivate von cycloalkanodionen, verfahren zu deren herstellung und deren pharmakologische anwendungen |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US7351732B2 (de) |
| EP (1) | EP1544201B1 (de) |
| JP (1) | JP2005539017A (de) |
| KR (1) | KR20050042471A (de) |
| CN (2) | CN101172977A (de) |
| AT (1) | ATE331717T1 (de) |
| AU (1) | AU2003254512A1 (de) |
| BR (1) | BR0313375A (de) |
| CA (1) | CA2492837A1 (de) |
| CY (1) | CY1106170T1 (de) |
| DE (1) | DE60306534T2 (de) |
| DK (1) | DK1544201T3 (de) |
| ES (2) | ES2199086B1 (de) |
| IL (1) | IL166469A0 (de) |
| MX (1) | MXPA05001245A (de) |
| NO (1) | NO20051068L (de) |
| NZ (1) | NZ538489A (de) |
| PL (1) | PL373644A1 (de) |
| PT (1) | PT1544201E (de) |
| RU (1) | RU2322445C2 (de) |
| UA (1) | UA79801C2 (de) |
| WO (1) | WO2004014915A1 (de) |
| ZA (1) | ZA200500784B (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2199086B1 (es) | 2002-07-31 | 2005-06-01 | Cepa Schwarz Pharma Sl | Nuevos derivados de cicloalcanodionas, procedimiento para su preparacion y sus aplicaciones farmacologicas. |
| ES2238015B1 (es) * | 2004-01-30 | 2006-11-01 | Cepa Schwarz Pharma, S.L. | Derivados de cicloalcanodionas con actividad neuroprotectora. |
| WO2008015538A2 (en) * | 2006-07-31 | 2008-02-07 | Schwarz Pharma S.L. | Use of diaza- and thiaza-cycloalkanediones for preventing and/or treating pain and /or migraine |
| EP2338873A1 (de) | 2009-12-22 | 2011-06-29 | Gmeiner, Peter | Neue Aminotetralinderivate |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4055410A (en) * | 1976-03-15 | 1977-10-25 | E. I. Du Pont De Nemours And Company | Substituted bromo- or chloroacetamide herbicides |
| EP0002978B1 (de) * | 1977-12-29 | 1982-10-06 | Synthelabo | Thiazolidindion-2,4 Derivate, deren Herstellung und Verwendung als Arzneimittel |
| DE3901814A1 (de) * | 1988-07-28 | 1990-02-01 | Bayer Ag | Substituierte aminomethylzetraline sowie ihre heterocyclischen analoga |
| EP0510691B1 (de) * | 1991-04-26 | 2004-11-03 | Osaka Bioscience Institute | Für ein menschliches Zelloberflächen-Antigen kodierende DNS |
| TW288010B (de) * | 1992-03-05 | 1996-10-11 | Pfizer | |
| AP486A (en) * | 1993-04-27 | 1996-04-16 | Pfizer | Indole derivatives. |
| WO1996006846A1 (es) | 1994-09-01 | 1996-03-07 | Universidad Complutense De Madrid | Nuevos derivados de arilpiperazinas |
| ES2082727B1 (es) | 1994-09-01 | 1996-10-16 | Univ Madrid Complutense | Nuevos derivados de arilpiperazinas. |
| ES2094690B1 (es) | 1994-11-22 | 1997-08-01 | Univ Madrid Complutense | Nuevos derivados de imida-piperazinas. |
| ES2109190B1 (es) | 1996-03-22 | 1998-07-01 | Univ Madrid Complutense | Nuevos derivados de bencimidazol con afinidad por los receptores serotoninergicos 5-ht /5-ht |
| ES2129370B1 (es) | 1997-09-23 | 2000-03-01 | Univ Madrid Complutense | Procedimiento para la obtencion del 2-(4-(4-(m-etilsulfonamidofenil)p iperazin-1-il(butil)-1,3-dioxoperhidropirrolo)1,2-c(imidazol |
| US6133277A (en) | 1997-12-05 | 2000-10-17 | Janssen Pharmaceutica N.V. | (Benzodioxan, benzofuran or benzopyran) derivatives having fundic relaxation properties |
| ES2154605B1 (es) | 1999-09-14 | 2001-11-16 | Univ Madrid Complutense | Nuevos derivados mixtos de bencimidazol-arilpiperazina con afinidad por los receptores serotoninergicos 5-ht1a y 5-ht3 |
| DE10148425A1 (de) | 2001-10-01 | 2003-04-17 | Bayer Ag | Chromane |
| ES2199086B1 (es) | 2002-07-31 | 2005-06-01 | Cepa Schwarz Pharma Sl | Nuevos derivados de cicloalcanodionas, procedimiento para su preparacion y sus aplicaciones farmacologicas. |
| ES2238015B1 (es) | 2004-01-30 | 2006-11-01 | Cepa Schwarz Pharma, S.L. | Derivados de cicloalcanodionas con actividad neuroprotectora. |
| EP1674103A1 (de) | 2004-12-27 | 2006-06-28 | Cepa Schwarz Pharma s.l. | Arylpiperazine Derivative als 5-HT1A Rezeptor Liganden |
-
2002
- 2002-07-31 ES ES200201811A patent/ES2199086B1/es not_active Expired - Fee Related
-
2003
- 2003-07-29 PT PT03784210T patent/PT1544201E/pt unknown
- 2003-07-29 JP JP2004526925A patent/JP2005539017A/ja active Pending
- 2003-07-29 AU AU2003254512A patent/AU2003254512A1/en not_active Abandoned
- 2003-07-29 CA CA002492837A patent/CA2492837A1/en not_active Abandoned
- 2003-07-29 CN CNA2007101694908A patent/CN101172977A/zh active Pending
- 2003-07-29 EP EP03784210A patent/EP1544201B1/de not_active Expired - Lifetime
- 2003-07-29 RU RU2005102821/04A patent/RU2322445C2/ru not_active IP Right Cessation
- 2003-07-29 AT AT03784210T patent/ATE331717T1/de not_active IP Right Cessation
- 2003-07-29 PL PL03373644A patent/PL373644A1/xx not_active Application Discontinuation
- 2003-07-29 WO PCT/ES2003/000394 patent/WO2004014915A1/es not_active Ceased
- 2003-07-29 BR BR0313375-3A patent/BR0313375A/pt not_active IP Right Cessation
- 2003-07-29 UA UAA200500843A patent/UA79801C2/uk unknown
- 2003-07-29 NZ NZ538489A patent/NZ538489A/en unknown
- 2003-07-29 DK DK03784210T patent/DK1544201T3/da active
- 2003-07-29 ES ES03784210T patent/ES2271673T3/es not_active Expired - Lifetime
- 2003-07-29 US US10/522,697 patent/US7351732B2/en not_active Expired - Fee Related
- 2003-07-29 CN CNB038183390A patent/CN100422185C/zh not_active Expired - Fee Related
- 2003-07-29 DE DE60306534T patent/DE60306534T2/de not_active Expired - Fee Related
- 2003-07-29 KR KR1020057001543A patent/KR20050042471A/ko not_active Ceased
- 2003-07-29 MX MXPA05001245A patent/MXPA05001245A/es active IP Right Grant
-
2005
- 2005-01-24 IL IL16646905A patent/IL166469A0/xx unknown
- 2005-01-25 ZA ZA200500784A patent/ZA200500784B/xx unknown
- 2005-02-25 NO NO20051068A patent/NO20051068L/no not_active Application Discontinuation
-
2006
- 2006-09-26 CY CY20061101376T patent/CY1106170T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RU2322445C2 (ru) | 2008-04-20 |
| ES2199086A1 (es) | 2004-02-01 |
| NZ538489A (en) | 2006-09-29 |
| ES2271673T3 (es) | 2007-04-16 |
| CN1671708A (zh) | 2005-09-21 |
| EP1544201B1 (de) | 2006-06-28 |
| KR20050042471A (ko) | 2005-05-09 |
| DE60306534T2 (de) | 2007-04-19 |
| US20050250777A1 (en) | 2005-11-10 |
| CN101172977A (zh) | 2008-05-07 |
| PL373644A1 (en) | 2005-09-05 |
| ZA200500784B (en) | 2006-08-30 |
| NO20051068L (no) | 2005-02-25 |
| AU2003254512A1 (en) | 2004-02-25 |
| BR0313375A (pt) | 2005-06-21 |
| ES2199086B1 (es) | 2005-06-01 |
| JP2005539017A (ja) | 2005-12-22 |
| MXPA05001245A (es) | 2005-09-12 |
| IL166469A0 (en) | 2006-01-15 |
| UA79801C2 (en) | 2007-07-25 |
| CY1106170T1 (el) | 2011-06-08 |
| RU2005102821A (ru) | 2005-10-10 |
| US7351732B2 (en) | 2008-04-01 |
| ATE331717T1 (de) | 2006-07-15 |
| EP1544201A1 (de) | 2005-06-22 |
| WO2004014915A1 (es) | 2004-02-19 |
| CN100422185C (zh) | 2008-10-01 |
| PT1544201E (pt) | 2006-11-30 |
| DK1544201T3 (da) | 2006-10-30 |
| CA2492837A1 (en) | 2004-02-19 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CY1109015T1 (el) | Διφαινυλ ενωσεις χρησιμες ως ανταγωνιστες μουσκαρινικου υποδοχεα | |
| CL2010000204A1 (es) | Compuestos intermediarios derivados de 4 amino-3-metoxibenzamida; compuesto intermediario n-{4-[4-(ciclopropilmetil)piperazin-1-il]ciclohexil}acetamida; compuesto intermediario 2-cloro-7-etil-7,8-dihidro-5-metil-8-(1-metiletil)-6(5h)-pteridinona, útiles en la preparación de dihidropteridinonas sustituidas (divisional sol. 2077-05). | |
| MX2007012883A (es) | Derivados de dihidrobenzofurano y usos de los mismos. | |
| DK1337518T3 (da) | Piperazinylpyrazinforbindelser som antagonister for serotonin-5-HT2-receptoren | |
| DE602004012858D1 (de) | 2-aminobenzothiazole als cb1 rezeptor inverse agonisten | |
| DE602006007556D1 (de) | Heteroarylsulfonylstilbene als 5-ht2a-antagonisten | |
| MX2007013065A (es) | Derivados de dihidrobenzofurano y usos de los mismos. | |
| MA29135B1 (fr) | Potentialisateurs de recepteurs du glutamate | |
| EA200600621A1 (ru) | Производные тетрагидронафталина, способ их получения и их применение в качестве противовоспалительных средств | |
| EA200101107A1 (ru) | Пуриновые производные | |
| PE20061297A1 (es) | Compuestos derivados de cromano y cromeno moduladores del receptor de serotonina 5-ht2c | |
| MX2007012936A (es) | Derivados de dihidrobenzofurano y usos de los mismos. | |
| BRPI0601282A (pt) | composição, e método de modificar a formação de hidrato de gás | |
| CY1109740T1 (el) | Νεα μεθοδος συνθεσης παραγωγων της 1,3,4,5 -τετραϋδρο-2η- 3-βενζαζεπιν-2-ονης και εφαρμογη στη συνθεση της ιβαβραδινης και των αλατων προσθηκης της σε ενα φαρμακευτικως αποδεκτο οξυ | |
| PE20191046A1 (es) | Compuestos, procedimiento de obtencion de los compuestos, composicion farmaceutica, uso de los compuestos y metodo de tratamiento de desordenes psiquiatricos y/o trastornos del sueno | |
| TW200720260A (en) | Prokineticin 1 receptor antagonists | |
| AR056103A1 (es) | Compuestos de(piran-piperidinil)benzimidazol, composiciones farmaceuticas que los comprenden, proceso de preparacion y usos en el tratamiento de afecciones mediadas por agonistas del receptor muscarinico m1 | |
| EA200700365A1 (ru) | Производные индол-2-карбоксамидина как антагонисты nmda рецептора | |
| CY1110276T1 (el) | Αμινοαρυλο σουλφοναμιδικα παραγωγα ως λειτουργικοι συνδετες 5-ητ6 | |
| ATE409179T1 (de) | Tetralin- und indanderivate und deren anwendungen als 5-ht-antagonisten | |
| EA200600688A1 (ru) | Арилинденпиридины и арилинденпиримидины и их применение в качестве антагонистов аденозинового рецептора а2а | |
| DE60306534D1 (de) | Neue derivate von cycloalkanodionen, verfahren zu deren herstellung und deren pharmakologische anwendungen | |
| AR024840A1 (es) | Compuestos de 5ht1 para terapia antidepresiva; composiciones farmaceuticas y su uso en la preparacion de medicamentos. | |
| PE20130512A1 (es) | Compuesto, composicion farmaceutica, uso de un compuesto y metodo para el tratamiento de los trastornos asociados a los receptores serotoninergicos 5-ht1a y 5-ht2a | |
| ATE486071T1 (de) | Azabicycloä3.1.0ühexan-derivate als modulatoren des dopamin-d3-rezeptors |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8327 | Change in the person/name/address of the patent owner |
Owner name: SCHWARZ PHARMA, S.L., MADRID, ES |
|
| 8364 | No opposition during term of opposition | ||
| 8328 | Change in the person/name/address of the agent |
Representative=s name: HOEFER & PARTNER, 81543 MUENCHEN |
|
| 8339 | Ceased/non-payment of the annual fee |