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DE60304060D1 - Kontinuierliches verfahren zur herstellung von fructopyranosesulfamatderivaten - Google Patents

Kontinuierliches verfahren zur herstellung von fructopyranosesulfamatderivaten

Info

Publication number
DE60304060D1
DE60304060D1 DE60304060T DE60304060T DE60304060D1 DE 60304060 D1 DE60304060 D1 DE 60304060D1 DE 60304060 T DE60304060 T DE 60304060T DE 60304060 T DE60304060 T DE 60304060T DE 60304060 D1 DE60304060 D1 DE 60304060D1
Authority
DE
Germany
Prior art keywords
fructopyranosesulfamate
derivatives
preparation
continuous process
continuous
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60304060T
Other languages
English (en)
Other versions
DE60304060T2 (de
Inventor
Thomas W Adkins
Charles F Cicco
Penina Feibush
Donald A Koch
Cynthia Maryanoff
Walter E Stalzer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceuticals Inc
Original Assignee
Ortho McNeil Pharmaceutical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho McNeil Pharmaceutical Inc filed Critical Ortho McNeil Pharmaceutical Inc
Publication of DE60304060D1 publication Critical patent/DE60304060D1/de
Application granted granted Critical
Publication of DE60304060T2 publication Critical patent/DE60304060T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H9/00Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
    • C07H9/02Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing only oxygen as ring hetero atoms
    • C07H9/04Cyclic acetals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H11/00Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE60304060T 2002-10-31 2003-10-27 Kontinuierliches verfahren zur herstellung von fructopyranosesulfamatderivaten Expired - Lifetime DE60304060T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US42255802P 2002-10-31 2002-10-31
US422558 2002-10-31
US691782 2003-10-23
US10/691,782 US7196209B2 (en) 2002-10-31 2003-10-23 Continuous process for the preparation of fructopyranose sulfamate derivatives
PCT/US2003/034107 WO2004041836A1 (en) 2002-10-31 2003-10-27 Continuous process for the preparation of fructopyranose sulfamate derivatives

Publications (2)

Publication Number Publication Date
DE60304060D1 true DE60304060D1 (de) 2006-05-11
DE60304060T2 DE60304060T2 (de) 2006-09-28

Family

ID=32314459

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60304060T Expired - Lifetime DE60304060T2 (de) 2002-10-31 2003-10-27 Kontinuierliches verfahren zur herstellung von fructopyranosesulfamatderivaten

Country Status (23)

Country Link
US (1) US7196209B2 (de)
EP (1) EP1558624B1 (de)
JP (1) JP4892191B2 (de)
KR (1) KR20050083838A (de)
AR (1) AR041742A1 (de)
AT (1) ATE320440T1 (de)
AU (1) AU2003285014A1 (de)
BR (1) BR0315892A (de)
CA (1) CA2504039A1 (de)
CY (1) CY1105040T1 (de)
DE (1) DE60304060T2 (de)
DK (1) DK1558624T3 (de)
ES (1) ES2260673T3 (de)
HR (1) HRP20050370A2 (de)
MX (1) MXPA05004647A (de)
MY (1) MY137066A (de)
NO (1) NO20052593D0 (de)
NZ (1) NZ539506A (de)
PL (1) PL376538A1 (de)
PT (1) PT1558624E (de)
RU (1) RU2317301C2 (de)
TW (1) TW200418867A (de)
WO (1) WO2004041836A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102725301B (zh) 2010-02-05 2015-05-13 台湾神隆股份有限公司 用于制造和纯化托吡酯的方法
US8652527B1 (en) 2013-03-13 2014-02-18 Upsher-Smith Laboratories, Inc Extended-release topiramate capsules
US9101545B2 (en) 2013-03-15 2015-08-11 Upsher-Smith Laboratories, Inc. Extended-release topiramate capsules

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4513006A (en) 1983-09-26 1985-04-23 Mcneil Lab., Inc. Anticonvulsant sulfamate derivatives
AU651244B2 (en) * 1991-09-19 1994-07-14 Mcneilab, Inc. Process for the preparation of chlorosulfate and sulfamate derivatives of 2,3:4,5-bis-0-(1-methylethylidene)-beta-D- fructopyranose and (1-methylcyclohexyl)methanol
US5242942A (en) * 1992-04-28 1993-09-07 Mcneilab, Inc. Anticonvulsant fructopyranose cyclic sulfites and sulfates
US5753693A (en) * 1996-06-28 1998-05-19 Ortho Pharmaceutical Corporation Anticonvulsant derivatives useful in treating manic-depressive bipolar disorder

Also Published As

Publication number Publication date
JP4892191B2 (ja) 2012-03-07
PL376538A1 (pl) 2006-01-09
NO20052593L (no) 2005-05-30
US7196209B2 (en) 2007-03-27
JP2006508949A (ja) 2006-03-16
NO20052593D0 (no) 2005-05-30
HRP20050370A2 (en) 2006-07-31
MXPA05004647A (es) 2005-09-20
CY1105040T1 (el) 2010-03-03
ATE320440T1 (de) 2006-04-15
AU2003285014A1 (en) 2004-06-07
ES2260673T3 (es) 2006-11-01
MY137066A (en) 2008-12-31
BR0315892A (pt) 2005-10-04
DE60304060T2 (de) 2006-09-28
RU2005113268A (ru) 2006-01-20
EP1558624A1 (de) 2005-08-03
RU2317301C2 (ru) 2008-02-20
WO2004041836A1 (en) 2004-05-21
US20040158081A1 (en) 2004-08-12
DK1558624T3 (da) 2006-05-15
EP1558624B1 (de) 2006-03-15
CA2504039A1 (en) 2004-05-21
NZ539506A (en) 2007-06-29
KR20050083838A (ko) 2005-08-26
TW200418867A (en) 2004-10-01
PT1558624E (pt) 2006-05-31
AR041742A1 (es) 2005-05-26

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition