DE60230147D1 - Verfahren zur überwachung und modulierung von proteinfaltung - Google Patents
Verfahren zur überwachung und modulierung von proteinfaltungInfo
- Publication number
- DE60230147D1 DE60230147D1 DE60230147T DE60230147T DE60230147D1 DE 60230147 D1 DE60230147 D1 DE 60230147D1 DE 60230147 T DE60230147 T DE 60230147T DE 60230147 T DE60230147 T DE 60230147T DE 60230147 D1 DE60230147 D1 DE 60230147D1
- Authority
- DE
- Germany
- Prior art keywords
- monitoring
- folding
- protein folding
- modulating protein
- expression
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000000034 method Methods 0.000 title abstract 3
- 230000012846 protein folding Effects 0.000 title abstract 2
- 238000012544 monitoring process Methods 0.000 title 1
- 108010006519 Molecular Chaperones Proteins 0.000 abstract 1
- 102000007056 Recombinant Fusion Proteins Human genes 0.000 abstract 1
- 108010008281 Recombinant Fusion Proteins Proteins 0.000 abstract 1
- 230000004186 co-expression Effects 0.000 abstract 1
- 230000014509 gene expression Effects 0.000 abstract 1
- 238000005259 measurement Methods 0.000 abstract 1
- 230000001737 promoting effect Effects 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01116371 | 2001-07-06 | ||
| PCT/EP2002/007346 WO2003004698A2 (en) | 2001-07-06 | 2002-07-03 | Method for monitoring and modulating protein folding |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60230147D1 true DE60230147D1 (de) | 2009-01-15 |
Family
ID=8177955
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60230147T Expired - Lifetime DE60230147D1 (de) | 2001-07-06 | 2002-07-03 | Verfahren zur überwachung und modulierung von proteinfaltung |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US7943300B2 (de) |
| EP (1) | EP1407052B1 (de) |
| JP (1) | JP4304336B2 (de) |
| AT (1) | ATE416260T1 (de) |
| CA (1) | CA2452849C (de) |
| DE (1) | DE60230147D1 (de) |
| DK (1) | DK1407052T3 (de) |
| ES (1) | ES2315384T3 (de) |
| PT (1) | PT1407052E (de) |
| WO (1) | WO2003004698A2 (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100746993B1 (ko) * | 2005-03-03 | 2007-08-08 | 한국생명공학연구원 | 대장균 발현 시스템을 이용한 인간 단백질 타이로신 탈인산화 효소의 발현 및 정제방법 |
| GB0610792D0 (en) | 2006-06-02 | 2006-07-12 | Remynd Nv | Methods and tools for the screening of factors affecting protein misfolding |
| US8722348B2 (en) | 2008-05-28 | 2014-05-13 | Wayne State University | Method and composition for a protein transduction technology and its applications |
| CN103826459B (zh) | 2011-05-02 | 2017-05-10 | 韦恩州立大学 | 蛋白质诱导的多能细胞技术及其用途 |
| ES2896021T3 (es) | 2013-10-25 | 2022-02-23 | Univ Wayne State | Proteína de reprogramación modificada para uso en el tratamiento de un cáncer |
| US9616114B1 (en) | 2014-09-18 | 2017-04-11 | David Gordon Bermudes | Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity |
| US10676723B2 (en) | 2015-05-11 | 2020-06-09 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| US11471497B1 (en) | 2019-03-13 | 2022-10-18 | David Gordon Bermudes | Copper chelation therapeutics |
| US10973908B1 (en) | 2020-05-14 | 2021-04-13 | David Gordon Bermudes | Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine |
| US12537071B1 (en) | 2020-07-22 | 2026-01-27 | David Gordon Bermudes | Bacteria having boolean control pathways expressing therapeutic proteins including immunotherapeutic cytotoxins |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR005035A1 (es) * | 1995-12-11 | 1999-04-07 | Merck Patent Ges Mit Beschränkter Haftung | Procedimiento para preparar proteinas recombinantes en e. coli, mediante fermentacion con gran concentracion de celulas. |
| EP1025246A1 (de) * | 1997-10-23 | 2000-08-09 | Plückthun, Andreas, Prof. Dr. | Verfahren zur identifizierung von nukleinsäureseqeunzen und (poly)peptide die die funktionelle periplasmatische proteinexpression erhöhen |
| US20030119094A1 (en) * | 2001-09-24 | 2003-06-26 | Irm Llc | Solubility reporter gene constructs |
-
2002
- 2002-07-03 WO PCT/EP2002/007346 patent/WO2003004698A2/en not_active Ceased
- 2002-07-03 JP JP2003510456A patent/JP4304336B2/ja not_active Expired - Fee Related
- 2002-07-03 US US10/482,728 patent/US7943300B2/en not_active Expired - Fee Related
- 2002-07-03 AT AT02758299T patent/ATE416260T1/de active
- 2002-07-03 PT PT02758299T patent/PT1407052E/pt unknown
- 2002-07-03 CA CA2452849A patent/CA2452849C/en not_active Expired - Fee Related
- 2002-07-03 ES ES02758299T patent/ES2315384T3/es not_active Expired - Lifetime
- 2002-07-03 EP EP02758299A patent/EP1407052B1/de not_active Expired - Lifetime
- 2002-07-03 DK DK02758299T patent/DK1407052T3/da active
- 2002-07-03 DE DE60230147T patent/DE60230147D1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DK1407052T3 (da) | 2009-02-09 |
| CA2452849C (en) | 2013-06-18 |
| JP4304336B2 (ja) | 2009-07-29 |
| PT1407052E (pt) | 2009-03-05 |
| EP1407052B1 (de) | 2008-12-03 |
| EP1407052A2 (de) | 2004-04-14 |
| JP2004533261A (ja) | 2004-11-04 |
| CA2452849A1 (en) | 2003-01-16 |
| US7943300B2 (en) | 2011-05-17 |
| WO2003004698A2 (en) | 2003-01-16 |
| ATE416260T1 (de) | 2008-12-15 |
| ES2315384T3 (es) | 2009-04-01 |
| US20040185528A1 (en) | 2004-09-23 |
| WO2003004698A3 (en) | 2003-10-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |