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DE60230614D1 - Elektroporationseinrichtung zur reduzierung der kontraktion von muskeln und der schmerzempfindung - Google Patents

Elektroporationseinrichtung zur reduzierung der kontraktion von muskeln und der schmerzempfindung

Info

Publication number
DE60230614D1
DE60230614D1 DE60230614T DE60230614T DE60230614D1 DE 60230614 D1 DE60230614 D1 DE 60230614D1 DE 60230614 T DE60230614 T DE 60230614T DE 60230614 T DE60230614 T DE 60230614T DE 60230614 D1 DE60230614 D1 DE 60230614D1
Authority
DE
Germany
Prior art keywords
electroporation device
cells
substrate
muscle contraction
reducing muscle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60230614T
Other languages
English (en)
Inventor
Damijan Miklavcic
Luis Mir
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
IGEA SpA
Original Assignee
IGEA SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by IGEA SpA filed Critical IGEA SpA
Application granted granted Critical
Publication of DE60230614D1 publication Critical patent/DE60230614D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0412—Specially adapted for transcutaneous electroporation, e.g. including drug reservoirs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/325—Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Electrotherapy Devices (AREA)
  • Massaging Devices (AREA)
  • Percussion Or Vibration Massage (AREA)
  • Finger-Pressure Massage (AREA)
DE60230614T 2001-06-04 2002-06-04 Elektroporationseinrichtung zur reduzierung der kontraktion von muskeln und der schmerzempfindung Expired - Lifetime DE60230614D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT2001TO000534A ITTO20010534A1 (it) 2001-06-04 2001-06-04 Dispositivo e metodo per elettroporazione che riduce la contrazione muscolare e la sensazione di dolore.
PCT/IT2002/000361 WO2002098504A1 (en) 2001-06-04 2002-06-04 Electroporation device which reduces muscle contraction and pain sensation

Publications (1)

Publication Number Publication Date
DE60230614D1 true DE60230614D1 (de) 2009-02-12

Family

ID=11458927

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60230614T Expired - Lifetime DE60230614D1 (de) 2001-06-04 2002-06-04 Elektroporationseinrichtung zur reduzierung der kontraktion von muskeln und der schmerzempfindung

Country Status (8)

Country Link
US (2) US20040236376A1 (de)
EP (1) EP1395333B1 (de)
AT (1) ATE419035T1 (de)
DE (1) DE60230614D1 (de)
DK (1) DK1395333T3 (de)
ES (1) ES2319742T3 (de)
IT (1) ITTO20010534A1 (de)
WO (1) WO2002098504A1 (de)

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US10702326B2 (en) 2011-07-15 2020-07-07 Virginia Tech Intellectual Properties, Inc. Device and method for electroporation based treatment of stenosis of a tubular body part
US9198733B2 (en) 2008-04-29 2015-12-01 Virginia Tech Intellectual Properties, Inc. Treatment planning for electroporation-based therapies
US9283051B2 (en) 2008-04-29 2016-03-15 Virginia Tech Intellectual Properties, Inc. System and method for estimating a treatment volume for administering electrical-energy based therapies
US9867652B2 (en) 2008-04-29 2018-01-16 Virginia Tech Intellectual Properties, Inc. Irreversible electroporation using tissue vasculature to treat aberrant cell masses or create tissue scaffolds
US11254926B2 (en) 2008-04-29 2022-02-22 Virginia Tech Intellectual Properties, Inc. Devices and methods for high frequency electroporation
US10117707B2 (en) 2008-04-29 2018-11-06 Virginia Tech Intellectual Properties, Inc. System and method for estimating tissue heating of a target ablation zone for electrical-energy based therapies
EP2280741A4 (de) 2008-04-29 2012-06-13 Virginia Tech Intell Prop Irreversible elektroporation zur erzeugung von gewebegerüsten
US10238447B2 (en) 2008-04-29 2019-03-26 Virginia Tech Intellectual Properties, Inc. System and method for ablating a tissue site by electroporation with real-time monitoring of treatment progress
US8992517B2 (en) 2008-04-29 2015-03-31 Virginia Tech Intellectual Properties Inc. Irreversible electroporation to treat aberrant cell masses
US10245098B2 (en) 2008-04-29 2019-04-02 Virginia Tech Intellectual Properties, Inc. Acute blood-brain barrier disruption using electrical energy based therapy
US11272979B2 (en) 2008-04-29 2022-03-15 Virginia Tech Intellectual Properties, Inc. System and method for estimating tissue heating of a target ablation zone for electrical-energy based therapies
US8926606B2 (en) 2009-04-09 2015-01-06 Virginia Tech Intellectual Properties, Inc. Integration of very short electric pulses for minimally to noninvasive electroporation
US10272178B2 (en) 2008-04-29 2019-04-30 Virginia Tech Intellectual Properties Inc. Methods for blood-brain barrier disruption using electrical energy
US8632534B2 (en) 2009-04-03 2014-01-21 Angiodynamics, Inc. Irreversible electroporation (IRE) for congestive obstructive pulmonary disease (COPD)
US11382681B2 (en) 2009-04-09 2022-07-12 Virginia Tech Intellectual Properties, Inc. Device and methods for delivery of high frequency electrical pulses for non-thermal ablation
US11638603B2 (en) 2009-04-09 2023-05-02 Virginia Tech Intellectual Properties, Inc. Selective modulation of intracellular effects of cells using pulsed electric fields
WO2010138919A2 (en) 2009-05-28 2010-12-02 Angiodynamics, Inc. System and method for synchronizing energy delivery to the cardiac rhythm
US9895189B2 (en) 2009-06-19 2018-02-20 Angiodynamics, Inc. Methods of sterilization and treating infection using irreversible electroporation
KR101030082B1 (ko) * 2010-09-10 2011-04-19 한국기계연구원 전기장 처치기 및 그 제조 방법
EP2627274B1 (de) 2010-10-13 2022-12-14 AngioDynamics, Inc. System zur elektrischen ableitung des gewebes eines patienten
WO2012088149A2 (en) 2010-12-20 2012-06-28 Virginia Tech Intellectual Properties, Inc. High-frequency electroporation for cancer therapy
US9078665B2 (en) 2011-09-28 2015-07-14 Angiodynamics, Inc. Multiple treatment zone ablation probe
US9414881B2 (en) 2012-02-08 2016-08-16 Angiodynamics, Inc. System and method for increasing a target zone for electrical ablation
WO2015175570A1 (en) 2014-05-12 2015-11-19 Virginia Tech Intellectual Properties, Inc. Selective modulation of intracellular effects of cells using pulsed electric fields
US12114911B2 (en) 2014-08-28 2024-10-15 Angiodynamics, Inc. System and method for ablating a tissue site by electroporation with real-time pulse monitoring
WO2016100325A1 (en) 2014-12-15 2016-06-23 Virginia Tech Intellectual Properties, Inc. Devices, systems, and methods for real-time monitoring of electrophysical effects during tissue treatment
JP7495778B2 (ja) 2015-10-07 2024-06-05 メイヨ・ファウンデーション・フォー・メディカル・エデュケーション・アンド・リサーチ 肥満又は糖尿病治療のためのエレクトロポレーション
US10188449B2 (en) * 2016-05-23 2019-01-29 Covidien Lp System and method for temperature enhanced irreversible electroporation
US10905492B2 (en) 2016-11-17 2021-02-02 Angiodynamics, Inc. Techniques for irreversible electroporation using a single-pole tine-style internal device communicating with an external surface electrode
EP3500199B1 (de) 2016-11-29 2021-07-28 St. Jude Medical, Cardiology Division, Inc. Elektroporationssystme und katheter für elektroporationssysteme
EP3576839B1 (de) 2017-04-10 2022-10-26 St. Jude Medical, Cardiology Division, Inc. Elektroporationssystem und verfahren zur vorbehandlung von gewebe für die elektroporationstherapie
US11607537B2 (en) 2017-12-05 2023-03-21 Virginia Tech Intellectual Properties, Inc. Method for treating neurological disorders, including tumors, with electroporation
US11925405B2 (en) 2018-03-13 2024-03-12 Virginia Tech Intellectual Properties, Inc. Treatment planning system for immunotherapy enhancement via non-thermal ablation
US11311329B2 (en) 2018-03-13 2022-04-26 Virginia Tech Intellectual Properties, Inc. Treatment planning for immunotherapy based treatments using non-thermal ablation techniques
US12390262B2 (en) 2018-03-13 2025-08-19 Virginia Tech Intellectual Properties, Inc. Treatment planning system for immunotherapy enhancement via non-thermal ablation
US11950835B2 (en) 2019-06-28 2024-04-09 Virginia Tech Intellectual Properties, Inc. Cycled pulsing to mitigate thermal damage for multi-electrode irreversible electroporation therapy
US12214189B2 (en) 2019-07-24 2025-02-04 Virginia Tech Intellectual Properties, Inc. Fourier analysis spectroscopy for monitoring tissue impedance changes and treatment outcome during electroporation-based-therapies
AU2020371627B2 (en) 2019-10-21 2025-12-11 Endogenex, Inc. Devices, systems, and methods for pulsed electric field treatment of the duodenum
WO2022035740A1 (en) * 2020-08-10 2022-02-17 Klett James Howard Systems and methods for duty cycle interferential current stimulation and therapy
US12485279B2 (en) 2020-11-25 2025-12-02 Virginia Tech Intellectual Properties, Inc. Methods for modulating temporal infrastructure of pulsed electric fields

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US5047007A (en) * 1989-12-22 1991-09-10 Medtronic, Inc. Method and apparatus for pulsed iontophoretic drug delivery
US5193537A (en) * 1990-06-12 1993-03-16 Zmd Corporation Method and apparatus for transcutaneous electrical cardiac pacing
US5634899A (en) * 1993-08-20 1997-06-03 Cortrak Medical, Inc. Simultaneous cardiac pacing and local drug delivery method
FR2703253B1 (fr) * 1993-03-30 1995-06-23 Centre Nat Rech Scient Applicateur d'impulsions electriques pour traitement de tissus biologiques.
US6055453A (en) * 1997-08-01 2000-04-25 Genetronics, Inc. Apparatus for addressing needle array electrodes for electroporation therapy
SE513814C2 (sv) * 1998-03-31 2000-11-06 Aditus Medical Ab Anordning för behandling av sjukdomar med elektriska fält
EP1102608A4 (de) * 1998-07-13 2008-09-17 Genetronics Inc Methode und gerät zur elektrisch unterstützten oberflächlichen auftragung von kosmetikmitteln
US6678558B1 (en) * 1999-03-25 2004-01-13 Genetronics, Inc. Method and apparatus for reducing electroporation-mediated muscle reaction and pain response
IT1320520B1 (it) * 2000-04-21 2003-12-10 Igea Srl Dispositivo e metodo di elettro-porazione in cui la misura delleproprieta' elettriche dei campioni svolta dopo l'emissione degli
US6928318B2 (en) * 2000-05-22 2005-08-09 Merck & Co., Inc. System and method for assessing the performance of a pharmaceutical agent delivery system
US6969449B2 (en) * 2000-07-10 2005-11-29 Vertex Pharmaceuticals (San Diego) Llc Multi-well plate and electrode assemblies for ion channel assays

Also Published As

Publication number Publication date
EP1395333A1 (de) 2004-03-10
ITTO20010534A0 (it) 2001-06-04
DK1395333T3 (da) 2009-04-06
EP1395333B1 (de) 2008-12-31
WO2002098504A1 (en) 2002-12-12
US20120116288A1 (en) 2012-05-10
US20040236376A1 (en) 2004-11-25
ATE419035T1 (de) 2009-01-15
ES2319742T3 (es) 2009-05-12
ITTO20010534A1 (it) 2002-12-04

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