DE60223707D1 - Calcium-l-threonat zur behandlung von knochenfrakturen - Google Patents
Calcium-l-threonat zur behandlung von knochenfrakturenInfo
- Publication number
- DE60223707D1 DE60223707D1 DE60223707T DE60223707T DE60223707D1 DE 60223707 D1 DE60223707 D1 DE 60223707D1 DE 60223707 T DE60223707 T DE 60223707T DE 60223707 T DE60223707 T DE 60223707T DE 60223707 D1 DE60223707 D1 DE 60223707D1
- Authority
- DE
- Germany
- Prior art keywords
- threonate
- calcium
- treatment
- bone fractures
- fractures
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 208000010392 Bone Fractures Diseases 0.000 title 1
- ZJXGOFZGZFVRHK-BALCVSAKSA-L calcium;(2r,3s)-2,3,4-trihydroxybutanoate Chemical compound [Ca+2].OC[C@H](O)[C@@H](O)C([O-])=O.OC[C@H](O)[C@@H](O)C([O-])=O ZJXGOFZGZFVRHK-BALCVSAKSA-L 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/191—Carboxylic acids, e.g. valproic acid having two or more hydroxy groups, e.g. gluconic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Physical Education & Sports Medicine (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN01119870 | 2001-07-03 | ||
| CNB011198702A CN1196480C (zh) | 2001-07-03 | 2001-07-03 | L-苏糖酸钙在制备预防或治疗骨折的药物中的用途 |
| PCT/CN2002/000468 WO2003004011A1 (en) | 2001-07-03 | 2002-07-02 | Calcium l-threonate for preventing or treating bone facture |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60223707D1 true DE60223707D1 (de) | 2008-01-03 |
| DE60223707T2 DE60223707T2 (de) | 2008-10-30 |
Family
ID=4663771
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60223707T Expired - Fee Related DE60223707T2 (de) | 2001-07-03 | 2002-07-02 | Calcium-l-threonat zur behandlung von knochenfrakturen |
| DE02748548T Pending DE02748548T1 (de) | 2001-07-03 | 2002-07-02 | Calcium-l-threonat zur prävention oder behandlung von knochenfrakturen |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE02748548T Pending DE02748548T1 (de) | 2001-07-03 | 2002-07-02 | Calcium-l-threonat zur prävention oder behandlung von knochenfrakturen |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6727288B2 (de) |
| EP (1) | EP1443918B1 (de) |
| JP (1) | JP2005519856A (de) |
| KR (1) | KR100737278B1 (de) |
| CN (1) | CN1196480C (de) |
| CA (1) | CA2471232A1 (de) |
| DE (2) | DE60223707T2 (de) |
| WO (1) | WO2003004011A1 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1197561C (zh) * | 2001-07-03 | 2005-04-20 | 北京巨能亚太生命科学研究中心 | L-苏糖酸钙在制备预防或治疗损及软骨的疾病的药物中的用途 |
| CN100367952C (zh) * | 2003-09-30 | 2008-02-13 | 戴向国 | 一种含有l-苏糖酸钙和大豆异黄酮的组合物 |
| US20050244499A1 (en) * | 2004-05-03 | 2005-11-03 | Robert Diaz | Method and device for reducing susceptibility to fractures in long bones |
| US20050244451A1 (en) * | 2004-05-03 | 2005-11-03 | Robert Diaz | Method and device for reducing susceptibility to fractures in vertebral bodies |
| KR20070039581A (ko) * | 2004-08-05 | 2007-04-12 | 고도 슈세이 가부시키가이샤 | 칼슘 흡수 촉진 조성물 |
| US20060089642A1 (en) * | 2004-10-27 | 2006-04-27 | Diaz Robert L | Prefracture spinal implant for osteoporotic unfractured bone |
| US20060223730A1 (en) * | 2005-04-04 | 2006-10-05 | Hl Distribution Company | Calcium supplements |
| US20080249178A1 (en) | 2007-03-22 | 2008-10-09 | Guosong Liu | Magnesium compositions and uses thereof for increasing lifespan |
| US8377473B2 (en) * | 2009-07-01 | 2013-02-19 | Magceutics, Inc. | Slow release magnesium composition and uses thereof |
| RU2548776C2 (ru) * | 2013-01-11 | 2015-04-20 | Общество С Ограниченной Ответственностью "Парафарм" | Способ и препарат для ускорения консолидации переломов костей |
| US11022600B2 (en) * | 2014-05-01 | 2021-06-01 | Shimadzu Corporation | Method for assessing state of differentiation of cells |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH07126181A (ja) * | 1993-11-05 | 1995-05-16 | Hoechst Japan Ltd | 骨折の予防および治療剤 |
| US5656598A (en) * | 1994-03-08 | 1997-08-12 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Use of fibroblast growth factors to stimulate bone growth |
| WO1996025165A1 (en) * | 1995-02-17 | 1996-08-22 | Merck & Co., Inc. | Method of lessening the risk of non-vertebral bone fractures |
| CN1039571C (zh) * | 1996-06-13 | 1998-08-26 | 北京巨能经贸发展有限责任公司 | L-苏糖酸钙的用途 |
| CN1053653C (zh) * | 1997-08-29 | 2000-06-21 | 北京巨能亚太生命科学研究中心 | 新l-苏糖酸衍生物 |
| CN1215592A (zh) * | 1997-10-28 | 1999-05-05 | 马斐文 | L-苏糖酸钙口服液 |
| CN1148175C (zh) * | 1998-07-08 | 2004-05-05 | 北京巨能亚太生命科学研究中心 | L-苏糖酸钙预防、抑制和治疗骨质疏松和佝偻病的用途 |
| CN1074762C (zh) * | 1998-08-18 | 2001-11-14 | 北京巨能亚太生命科学研究中心 | L-苏糖酸铬盐、其制备方法及其应用 |
| CN1133379C (zh) * | 2001-02-20 | 2004-01-07 | 北京巨能亚太生命科学研究中心 | 一种等渗运动饮料及其制备方法 |
-
2001
- 2001-07-03 CN CNB011198702A patent/CN1196480C/zh not_active Expired - Fee Related
- 2001-12-31 US US10/039,194 patent/US6727288B2/en not_active Expired - Lifetime
-
2002
- 2002-07-02 DE DE60223707T patent/DE60223707T2/de not_active Expired - Fee Related
- 2002-07-02 EP EP02748548A patent/EP1443918B1/de not_active Expired - Lifetime
- 2002-07-02 JP JP2003510022A patent/JP2005519856A/ja active Pending
- 2002-07-02 KR KR1020037016574A patent/KR100737278B1/ko not_active Expired - Fee Related
- 2002-07-02 DE DE02748548T patent/DE02748548T1/de active Pending
- 2002-07-02 WO PCT/CN2002/000468 patent/WO2003004011A1/en not_active Ceased
- 2002-07-02 CA CA002471232A patent/CA2471232A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1443918A1 (de) | 2004-08-11 |
| EP1443918B1 (de) | 2007-11-21 |
| WO2003004011A1 (en) | 2003-01-16 |
| DE60223707T2 (de) | 2008-10-30 |
| KR100737278B1 (ko) | 2007-07-09 |
| CN1328820A (zh) | 2002-01-02 |
| EP1443918A4 (de) | 2004-11-24 |
| DE02748548T1 (de) | 2004-11-11 |
| JP2005519856A (ja) | 2005-07-07 |
| CN1196480C (zh) | 2005-04-13 |
| KR20040011541A (ko) | 2004-02-05 |
| CA2471232A1 (en) | 2003-01-16 |
| US6727288B2 (en) | 2004-04-27 |
| US20020169210A1 (en) | 2002-11-14 |
| HK1063603A1 (en) | 2005-01-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |