DE60219965D1 - Lang wirkende zusammensetzungen enthaltend zidovudine und/oder lamivudine - Google Patents

Lang wirkende zusammensetzungen enthaltend zidovudine und/oder lamivudine

Info

Publication number: DE60219965D1
Authority: DE; Germany
Prior art keywords: zidovudine; water soluble; lamivudine; pharmaceutically acceptable; active ingredient
Prior art date: 2002-04-23
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Fee Related

Application number

DE60219965T

Other languages

English (en)

Other versions

DE60219965T2 (de

Inventor

Himadri Sen

Surya Kumar Jayanthi

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Lupin Ltd

Original Assignee

Lupin Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-04-23

Filing date

2002-04-23

Publication date

2007-06-14

2002-04-23 Application filed by Lupin Ltd filed Critical Lupin Ltd

2007-06-14 Application granted granted Critical

2007-06-14 Publication of DE60219965D1 publication Critical patent/DE60219965D1/de

2008-01-17 Publication of DE60219965T2 publication Critical patent/DE60219965T2/de

2022-04-24 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Links

239000000203 mixture Substances 0.000 title abstract 3
229960002555 zidovudine Drugs 0.000 title abstract 2
HBOMLICNUCNMMY-XLPZGREQSA-N zidovudine Chemical compound O=C1NC(=O)C(C)=CN1[C@@H]1O[C@H](CO)[C@@H](N=[N+]=[N-])C1 HBOMLICNUCNMMY-XLPZGREQSA-N 0.000 title abstract 2
229960001627 lamivudine Drugs 0.000 title 1
JTEGQNOMFQHVDC-NKWVEPMBSA-N lamivudine Chemical compound O=C1N=C(N)C=CN1[C@H]1O[C@@H](CO)SC1 JTEGQNOMFQHVDC-NKWVEPMBSA-N 0.000 title 1
239000007788 liquid Substances 0.000 title 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 5
239000004480 active ingredient Substances 0.000 abstract 2
159000000007 calcium salts Chemical class 0.000 abstract 2
238000013270 controlled release Methods 0.000 abstract 2
239000003085 diluting agent Substances 0.000 abstract 2
229920001477 hydrophilic polymer Polymers 0.000 abstract 2
239000011159 matrix material Substances 0.000 abstract 2
239000008194 pharmaceutical composition Substances 0.000 abstract 2
IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 abstract 1
LHCOVOKZWQYODM-CPEOKENHSA-N 4-amino-1-[(2r,5s)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one;1-[(2r,4s,5s)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione Chemical compound O=C1N=C(N)C=CN1[C@H]1O[C@@H](CO)SC1.O=C1NC(=O)C(C)=CN1[C@@H]1O[C@H](CO)[C@@H](N=[N+]=[N-])C1 LHCOVOKZWQYODM-CPEOKENHSA-N 0.000 abstract 1
229920002907 Guar gum Polymers 0.000 abstract 1
239000000665 guar gum Substances 0.000 abstract 1
235000010417 guar gum Nutrition 0.000 abstract 1
229960002154 guar gum Drugs 0.000 abstract 1
239000001866 hydroxypropyl methyl cellulose Substances 0.000 abstract 1
235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 abstract 1
229920003088 hydroxypropyl methyl cellulose Polymers 0.000 abstract 1
UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 abstract 1
239000000661 sodium alginate Substances 0.000 abstract 1
235000010413 sodium alginate Nutrition 0.000 abstract 1
229940005550 sodium alginate Drugs 0.000 abstract 1
239000003381 stabilizer Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
- A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Molecular Biology (AREA)
Virology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Tropical Medicine & Parasitology (AREA)
AIDS & HIV (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)

DE60219965T 2002-04-23 2002-04-23 Lang wirkende zusammensetzungen enthaltend zidovudine und/oder lamivudine Expired - Fee Related DE60219965T2 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
PCT/IN2002/000110 WO2003090762A1 (en)	2002-04-23	2002-04-23	Long acting compositions comprising zidovudine and lamivudine

Publications (2)

Publication Number	Publication Date
DE60219965D1 true DE60219965D1 (de)	2007-06-14
DE60219965T2 DE60219965T2 (de)	2008-01-17

Family

ID=29266770

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE60219965T Expired - Fee Related DE60219965T2 (de)	2002-04-23	2002-04-23	Lang wirkende zusammensetzungen enthaltend zidovudine und/oder lamivudine

Country Status (12)

Country	Link
US (1)	US20050175694A1 (de)
EP (1)	EP1501521B1 (de)
AT (1)	ATE361080T1 (de)
AU (1)	AU2002311622A1 (de)
BR (1)	BR0215707A (de)
CZ (1)	CZ20041117A3 (de)
DE (1)	DE60219965T2 (de)
ES (1)	ES2286258T3 (de)
HU (1)	HUP0500217A2 (de)
MX (1)	MXPA04010436A (de)
SK (1)	SK285383B6 (de)
WO (1)	WO2003090762A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AP2008004533A0 (en) *	2005-12-14	2008-08-31	Cipla Ltd	Pharmaceutical combination
EP2276464A2 (de) *	2008-04-15	2011-01-26	Mallinckrodt Inc.	Kombinationen aus viruziden und anderen verbindungen
CN102488671A (zh) *	2011-12-15	2012-06-13	合肥华方医药科技有限公司	一种拉米夫定控释片制剂及其制备方法
AR118580A1 (es) *	2019-04-05	2021-10-20	Gedea Biotech Ab	Formulación de tableta vaginal
CN115813970B (zh) *	2022-11-25	2024-05-07	深圳福山生物科技有限公司	一种稳定释放的营养靶向组合物及其用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4036228A (en) *	1975-09-11	1977-07-19	Alza Corporation	Osmotic dispenser with gas generating means
FI950439A0 (fi) *	1992-08-04	1995-02-01	James M Dunn	3'-atsido-3'-deoksitymidiinin kontrolloidusti vapauttavat farmaseuttiset valmisteet ja käyttömenetelmät
GB9622681D0 (en) *	1996-10-31	1997-01-08	Glaxo Group Ltd	Pharmaceutical compositions
US6113920A (en) *	1996-10-31	2000-09-05	Glaxo Wellcome Inc.	Pharmaceutical compositions
GB9809213D0 (en) *	1998-04-29	1998-07-01	Glaxo Group Ltd	Pharmaceutical compositions
EA004443B1 (ru) *	1998-09-14	2004-04-29	Рэнбакси Лабораториз Лимитед	Лекарственная форма для контролируемого высвобождения ципрофлоксацина для приема один раз в день

2002
- 2002-04-23 BR BR0215707-1A patent/BR0215707A/pt not_active IP Right Cessation
- 2002-04-23 HU HU0500217A patent/HUP0500217A2/hu unknown
- 2002-04-23 WO PCT/IN2002/000110 patent/WO2003090762A1/en not_active Ceased
- 2002-04-23 SK SK5022-2004A patent/SK285383B6/sk not_active IP Right Cessation
- 2002-04-23 US US10/512,464 patent/US20050175694A1/en not_active Abandoned
- 2002-04-23 AT AT02738611T patent/ATE361080T1/de not_active IP Right Cessation
- 2002-04-23 DE DE60219965T patent/DE60219965T2/de not_active Expired - Fee Related
- 2002-04-23 ES ES02738611T patent/ES2286258T3/es not_active Expired - Lifetime
- 2002-04-23 AU AU2002311622A patent/AU2002311622A1/en not_active Abandoned
- 2002-04-23 MX MXPA04010436A patent/MXPA04010436A/es active IP Right Grant
- 2002-04-23 CZ CZ20041117A patent/CZ20041117A3/cs unknown
- 2002-04-23 EP EP02738611A patent/EP1501521B1/de not_active Expired - Lifetime

Also Published As

Publication number	Publication date
EP1501521B1 (de)	2007-05-02
DE60219965T2 (de)	2008-01-17
SK50222004A3 (sk)	2005-05-05
ES2286258T3 (es)	2007-12-01
MXPA04010436A (es)	2005-05-27
WO2003090762A1 (en)	2003-11-06
ATE361080T1 (de)	2007-05-15
SK285383B6 (sk)	2006-12-07
AU2002311622A1 (en)	2003-11-10
HUP0500217A2 (hu)	2005-06-28
EP1501521A1 (de)	2005-02-02
BR0215707A (pt)	2005-05-03
US20050175694A1 (en)	2005-08-11
CZ20041117A3 (cs)	2005-04-13

Publication	Publication Date	Title
Sinha et al.	2004	Colonic drug delivery of 5-fluorouracil: an in vitro evaluation
KR100283709B1 (ko)	2001-03-02	안정한 서방성 경구 투여 조성물
DK0923934T3 (da)	2003-11-24	Modified release-matrixformulering af cefaclor og cephalexin
EA200700049A1 (ru)	2007-04-27	Препаративные формы оральных лекарственных форм мемантина с модифицированным высвобождением
WO2004108162A3 (en)	2005-03-10	Controlled release pharmaceutical composition
IE970588A1 (en)	2000-08-23	Controlled release pharmaceutical compositions containing tiagabine
BR0009437A (pt)	2002-01-15	Amido pré-gelatinizado em uma formulação de liberação controlada
RU2333745C2 (ru)	2008-09-20	Композиции с контролируемым высвобождением
ATE424810T1 (de)	2009-03-15	Ein hydrokolloid und einen celluloseether enthaltende tablette mit verzögerter freisetzung
BR0312347A (pt)	2005-04-12	Composição farmacêutica oral, usos da espessura de revestimento de um material de revestimento dependente do ph de dissolução, de um material de revestimento, e de um material de polimetacrilato
DE60032749D1 (de)	2007-02-15	Stabilisierte pharmazeutische zusammensetzung enthaltend einen nichtsteroiden entzündungshemmenden wirkstoff und prostaglandin
WO2007048219A3 (en)	2007-07-19	Sustained drug release composition
MX2008000099A (es)	2008-03-19	Composiciones farmaceuticas de liberacion modificada novedosas, y procedimiento de preparacion de dichas composiciones.
BG105339A (en)	2001-11-30	Orally administered controlled drug delivery system providing temporal and spatial control
SK282506B6 (sk)	2002-10-08	Tableta obsahujúca paracetamol a domperidon
CA2352211A1 (en)	2001-04-05	Sustained release matrix systems for highly soluble drugs
EP0966966A3 (de)	2000-02-09	Nefazodon enthaltende Dosierungsform
DE60219965D1 (de)	2007-06-14	Lang wirkende zusammensetzungen enthaltend zidovudine und/oder lamivudine
WO2004078111A3 (en)	2004-10-28	Extended release minocycline compositions and processes for their preparation
UA89349C2 (uk)	2010-01-25	Таблетка без покриття, яка містить оланзапін, та спосіб її одержання
SG145717A1 (en)	2008-09-29	Composition for releasing a weak base for an extended period of time
PT1461017E (pt)	2006-07-31	Composicao farmaceutica para a libertacao controlada de um antibiotico beta-lactamico
NO20073850L (no)	2007-10-10	Farmasoytisk polymersammensetning for oral kontrollert frigivelsesavlevering av terbutalinsulfat
MXPA06007511A (es)	2009-06-10	Revestimientos de granulos de farmaco que imparten resistencia a la embarradura durante la compresion mecanica.
CN101848706A (zh)	2010-09-29	包含底物和含活性成分和聚乙烯醇的包衣的药用组合物

Legal Events

Date	Code	Title	Description
2008-05-21	8364	No opposition during term of opposition
2010-02-18	8339	Ceased/non-payment of the annual fee