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DE60212425D1 - Fsh-zusammensetzungen mit hohem sialylierungsgrad und deren verwendung zur herstellung von arzneimitteln - Google Patents

Fsh-zusammensetzungen mit hohem sialylierungsgrad und deren verwendung zur herstellung von arzneimitteln

Info

Publication number
DE60212425D1
DE60212425D1 DE60212425T DE60212425T DE60212425D1 DE 60212425 D1 DE60212425 D1 DE 60212425D1 DE 60212425 T DE60212425 T DE 60212425T DE 60212425 T DE60212425 T DE 60212425T DE 60212425 D1 DE60212425 D1 DE 60212425D1
Authority
DE
Germany
Prior art keywords
medicaments
preparation
high sialylation
sialylation rate
fsh compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Revoked
Application number
DE60212425T
Other languages
English (en)
Other versions
DE60212425T2 (de
Inventor
Ernest Loumaye
Carlo Emanuele Giartosio
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Serono SA
Original Assignee
Applied Research Systems ARS Holding NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23323355&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE60212425(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Applied Research Systems ARS Holding NV filed Critical Applied Research Systems ARS Holding NV
Application granted granted Critical
Publication of DE60212425D1 publication Critical patent/DE60212425D1/de
Publication of DE60212425T2 publication Critical patent/DE60212425T2/de
Anticipated expiration legal-status Critical
Revoked legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Endocrinology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Reproductive Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
DE60212425T 2001-10-22 2002-10-15 Fsh-zusammensetzungen mit hohem sialylierungsgrad und deren verwendung zur herstellung von arzneimitteln Revoked DE60212425T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US33808801P 2001-10-22 2001-10-22
US338088P 2001-10-22
PCT/EP2002/011501 WO2003035686A2 (en) 2001-10-22 2002-10-15 Compositions of fsh with high sialylation degree and their use for the preparation of medicaments

Publications (2)

Publication Number Publication Date
DE60212425D1 true DE60212425D1 (de) 2006-07-27
DE60212425T2 DE60212425T2 (de) 2006-11-09

Family

ID=23323355

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60212425T Revoked DE60212425T2 (de) 2001-10-22 2002-10-15 Fsh-zusammensetzungen mit hohem sialylierungsgrad und deren verwendung zur herstellung von arzneimitteln

Country Status (24)

Country Link
US (1) US20050085412A1 (de)
EP (2) EP1621549A3 (de)
JP (1) JP2005515974A (de)
KR (1) KR100929971B1 (de)
CN (1) CN1608078B (de)
AR (1) AR036926A1 (de)
AT (1) ATE329930T1 (de)
AU (1) AU2002340562B2 (de)
CA (1) CA2464368A1 (de)
DE (1) DE60212425T2 (de)
DK (1) DK1438336T3 (de)
EA (1) EA007030B1 (de)
ES (1) ES2261740T3 (de)
HR (1) HRP20040278B1 (de)
IL (2) IL161235A0 (de)
ME (1) MEP38608A (de)
MX (1) MXPA04003352A (de)
NO (1) NO327966B1 (de)
PL (1) PL369606A1 (de)
PT (1) PT1438336E (de)
RS (1) RS32804A (de)
UA (1) UA87433C2 (de)
WO (1) WO2003035686A2 (de)
ZA (1) ZA200402279B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0524782D0 (en) * 2005-12-05 2006-01-11 Chiron Srl Analysis of samples
AU2007294122B2 (en) * 2006-09-10 2013-03-07 Glycotope Gmbh Use of human cells of myeloid leukaemia origin for expression of antibodies
CN101264096B (zh) * 2007-03-12 2011-11-09 中国医学科学院药物研究所 人参皂苷Rg1在制备生精产品中的应用
US8742079B2 (en) 2007-08-20 2014-06-03 Protalix Ltd. Saccharide-containing protein conjugates and uses thereof
TWI488640B (zh) * 2008-04-16 2015-06-21 菲瑞茵國際中心股份有限公司 藥學製劑
JP2012524628A (ja) * 2009-04-22 2012-10-18 ザ リージェンツ オブ ザ ユニヴァーシティー オブ カリフォルニア 精巣の機能及び疾患の診断のためのｉｎｖｉｖｏでの１Ｈ磁気共鳴分光法
TWI532495B (zh) * 2009-10-05 2016-05-11 菲瑞茵國際中心股份有限公司 藥學製劑
US9194011B2 (en) 2009-11-17 2015-11-24 Protalix Ltd. Stabilized alpha-galactosidase and uses thereof
WO2012016576A1 (en) * 2010-08-04 2012-02-09 Glycotope Gmbh Improved recombinant human follicle-stimulating hormone
CN102464713A (zh) * 2010-12-21 2012-05-23 上海丽珠制药有限公司 一种卵泡刺激素的制备方法
WO2012098537A1 (en) 2011-01-20 2012-07-26 Protalix Ltd. Nucleic acid construct for expression of alpha-galactosidase in plants and plant cells
WO2012131306A1 (en) 2011-03-31 2012-10-04 Ferring B.V. Pharmaceutical preparation
AR090095A1 (es) * 2011-06-06 2014-10-22 Ferring Bv Preparacion farmaceutica que comprende hormona estimulante del foliculo recombinante
JO3092B1 (ar) * 2011-08-08 2017-03-15 Ferring Bv مركب لتحفيز مسيطر عليه للمبيض
WO2015158875A1 (en) 2014-04-18 2015-10-22 Glycotope Gmbh Controlled ovarian hyperstimulation with improved recombinant human follicle-stimulating hormone
HRP20230787T1 (hr) 2018-05-18 2023-10-27 Glycotope Gmbh Anti-muc1 antitijelo

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1057895B (it) * 1975-02-17 1982-03-30 Serono Lab Gonadotropina corionica umana parzialmente desalinizzata per indurre l'ouvulazione
IT1206302B (it) * 1987-06-26 1989-04-14 Serono Cesare Ist Ricerca Ormone follicolo-stimolante urinario
US6225449B1 (en) * 1991-10-04 2001-05-01 Washington University Hormone analogs with multiple CTP extensions
US5338835A (en) * 1989-02-21 1994-08-16 Washington University CTP-extended form of FSH
US5087615A (en) * 1989-03-17 1992-02-11 Applied Research Systems Ars Holding N.V. Novel method of ovulation induction in humans
US5541083A (en) * 1989-10-24 1996-07-30 The Regents Of The University Of California Method for producing secretable glycosyltransferases and other golgi processing enzymes
US5834251A (en) * 1994-12-30 1998-11-10 Alko Group Ltd. Methods of modifying carbohydrate moieties
AU736993B2 (en) * 1997-01-16 2001-08-09 Novo Nordisk A/S Practical in vitro sialylation of recombinant glycoproteins
DE69931975T2 (de) * 1998-08-07 2006-10-05 Applied Research Systems Ars Holding N.V. FSH Mimetika zur Behandlung von Infertilität
CA2348430A1 (en) * 1998-10-28 2000-05-04 Baylor College Of Medicine Ovary-specific genes and proteins
DE60032349T2 (de) * 1999-04-26 2007-07-12 Genentech, Inc., South San Francisco Zellenzuchtverfahren für glycoproteine
JP2001299362A (ja) * 1999-12-17 2001-10-30 Takeda Chem Ind Ltd 新規ポリペプチドおよびそのｄｎａ
AU2001231531A1 (en) * 2000-02-11 2001-08-20 Maxygen Aps Follicle stimulating hormones

Also Published As

Publication number Publication date
CA2464368A1 (en) 2003-05-01
PL369606A1 (en) 2005-05-02
NO20042061L (no) 2004-07-13
HRP20040278B1 (hr) 2008-03-31
KR20040045885A (ko) 2004-06-02
DE60212425T2 (de) 2006-11-09
EA200400574A1 (ru) 2004-08-26
PT1438336E (pt) 2006-08-31
ATE329930T1 (de) 2006-07-15
EA007030B1 (ru) 2006-06-30
MXPA04003352A (es) 2004-07-08
JP2005515974A (ja) 2005-06-02
AR036926A1 (es) 2004-10-13
ZA200402279B (en) 2005-10-26
WO2003035686A2 (en) 2003-05-01
IL161235A0 (en) 2004-09-27
NO327966B1 (no) 2009-11-02
EP1621549A2 (de) 2006-02-01
CN1608078A (zh) 2005-04-20
EP1621549A3 (de) 2006-03-01
DK1438336T3 (da) 2006-10-02
IL161235A (en) 2009-07-20
HRP20040278A2 (en) 2005-04-30
AU2002340562B2 (en) 2008-10-23
RS32804A (sr) 2007-02-05
KR100929971B1 (ko) 2009-12-04
MEP38608A (en) 2011-02-10
CN1608078B (zh) 2012-07-25
EP1438336A2 (de) 2004-07-21
ES2261740T3 (es) 2006-11-16
EP1438336B1 (de) 2006-06-14
UA87433C2 (ru) 2009-07-27
WO2003035686A3 (en) 2003-10-09
US20050085412A1 (en) 2005-04-21

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Legal Events

Date Code Title Description
8363 Opposition against the patent
8327 Change in the person/name/address of the patent owner

Owner name: LABORATOIRES SERONO S.A., COINSINS, VAUD, CH

8331 Complete revocation