DE602007011563D1 - Vorrichtung zur analyse einer fluid-probe durch mikrodialyse und verfahren zum überwachen eines parameters einer fluid-probe - Google Patents
Vorrichtung zur analyse einer fluid-probe durch mikrodialyse und verfahren zum überwachen eines parameters einer fluid-probeInfo
- Publication number
- DE602007011563D1 DE602007011563D1 DE602007011563T DE602007011563T DE602007011563D1 DE 602007011563 D1 DE602007011563 D1 DE 602007011563D1 DE 602007011563 T DE602007011563 T DE 602007011563T DE 602007011563 T DE602007011563 T DE 602007011563T DE 602007011563 D1 DE602007011563 D1 DE 602007011563D1
- Authority
- DE
- Germany
- Prior art keywords
- fluid sample
- microdialysis
- parameter
- monitoring
- analyzing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 238000001690 micro-dialysis Methods 0.000 title abstract 2
- 238000012544 monitoring process Methods 0.000 title abstract 2
- 239000012530 fluid Substances 0.000 title 2
- 238000000034 method Methods 0.000 title 1
- 239000012528 membrane Substances 0.000 abstract 4
- 239000000385 dialysis solution Substances 0.000 abstract 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D69/00—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
- B01D69/02—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor characterised by their properties
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/14525—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using microdialysis
- A61B5/14528—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using microdialysis invasively
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
- A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
- A61B5/686—Permanently implanted devices, e.g. pacemakers, other stimulators, biochips
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1601—Control or regulation
- A61M1/1619—Sampled collection of used dialysate, i.e. obviating the need for recovery of whole dialysate quantity for post-dialysis analysis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1678—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes intracorporal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
- A61M1/3403—Regulation parameters
- A61M1/3406—Physical characteristics of the filtrate, e.g. urea
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
- B01D63/02—Hollow fibre modules
- B01D63/031—Two or more types of hollow fibres within one bundle or within one potting or tube-sheet
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
- B01D63/08—Flat membrane modules
- B01D63/087—Single membrane modules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/50—General characteristics of the apparatus with microprocessors or computers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2313/00—Details relating to membrane modules or apparatus
- B01D2313/08—Flow guidance means within the module or the apparatus
- B01D2313/086—Meandering flow path over the membrane
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2325/00—Details relating to properties of membranes
- B01D2325/02—Details relating to pores or porosity of the membranes
- B01D2325/022—Asymmetric membranes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2325/00—Details relating to properties of membranes
- B01D2325/28—Degradation or stability over time
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2325/00—Details relating to properties of membranes
- B01D2325/48—Antimicrobial properties
Landscapes
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Urology & Nephrology (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Hematology (AREA)
- Vascular Medicine (AREA)
- Anesthesiology (AREA)
- Emergency Medicine (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Chemical & Material Sciences (AREA)
- Pathology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Medical Informatics (AREA)
- Surgery (AREA)
- Optics & Photonics (AREA)
- External Artificial Organs (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Sampling And Sample Adjustment (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US86210006P | 2006-10-19 | 2006-10-19 | |
| PCT/EP2007/009056 WO2008046630A1 (en) | 2006-10-19 | 2007-10-18 | Devices for and methods of monitoring a parameter of a fluidic sample by microdialysis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE602007011563D1 true DE602007011563D1 (de) | 2011-02-10 |
Family
ID=39083233
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE602007011563T Active DE602007011563D1 (de) | 2006-10-19 | 2007-10-18 | Vorrichtung zur analyse einer fluid-probe durch mikrodialyse und verfahren zum überwachen eines parameters einer fluid-probe |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US8535537B2 (de) |
| EP (1) | EP1962993B1 (de) |
| AT (1) | ATE493194T1 (de) |
| DE (1) | DE602007011563D1 (de) |
| WO (1) | WO2008046630A1 (de) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103083747B (zh) * | 2011-10-31 | 2016-08-31 | 深圳光启高等理工研究院 | 一种气液交换器 |
| WO2015110277A1 (de) * | 2014-01-21 | 2015-07-30 | Nephro-Solutions Ag | Dialysegerät mit einem dialysator |
| EP4335539A3 (de) | 2014-03-29 | 2024-05-01 | Princeton Trade and Technology Inc. | Blutverarbeitungskartuschen und -systeme sowie verfahren für extrakorporale bluttherapien |
| WO2016014987A2 (en) | 2014-07-24 | 2016-01-28 | Thomas Jefferson University | Long-term implantable monitoring system & methods of use |
| WO2016129401A1 (ja) * | 2015-02-13 | 2016-08-18 | 株式会社 村田製作所 | 送受信モジュール |
| US10426884B2 (en) | 2015-06-26 | 2019-10-01 | Novaflux Inc. | Cartridges and systems for outside-in flow in membrane-based therapies |
| US10399040B2 (en) | 2015-09-24 | 2019-09-03 | Novaflux Inc. | Cartridges and systems for membrane-based therapies |
| US10709827B2 (en) | 2015-10-14 | 2020-07-14 | Technische Universität Wien | Membrane catheter |
| JP6899590B2 (ja) | 2015-10-14 | 2021-07-07 | シーコア テクノロジー ゲーエムベーハー | 膜型カテーテル |
| WO2017100028A1 (en) | 2015-12-08 | 2017-06-15 | The Regents Of The University Of Michigan | Microfabrication of a microdialysis probe with nanoporous membrane |
| JP6715038B2 (ja) * | 2016-03-09 | 2020-07-01 | 学校法人慶應義塾 | 血液濾過装置 |
| EP3600493A4 (de) | 2017-03-31 | 2020-08-19 | Capillary Biomedical, Inc. | Infusionsvorrichtung mit schraubeneinsatz |
| CN108854599B (zh) * | 2018-05-14 | 2020-10-16 | 陕西师范大学 | 一种基于交联溶菌酶的透析膜及其应用 |
| EP3877018A4 (de) | 2018-11-08 | 2022-08-10 | Capillary Biomedical, Inc. | Lineare einführvorrichtung mit drehantrieb |
| DE102019007144A1 (de) * | 2019-10-15 | 2021-04-15 | ProMedTec Germany GmbH | Verfahren und Anordnung zur Verbesserung des Austausches von Gasen über semipermeable Membranen im wässrigen Milieu |
| US20230314396A1 (en) * | 2020-04-20 | 2023-10-05 | Ortiv-Q3 Research Pvt. Ltd | System and method for microdialysis for in-vitro release testing of dosage forms |
| WO2022047199A1 (en) | 2020-08-28 | 2022-03-03 | Capillary Biomedical, Inc. | Insulin infusion set |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0038866A3 (de) | 1980-04-26 | 1982-03-17 | Ghen M. G. Raj | Kompakter Dialysator mit geringer Austauschfläche, Verfahren und Gerät |
| FR2497114A1 (fr) | 1980-12-31 | 1982-07-02 | Hospal Sodip | Appareil, utilisable comme hemodialyseur, comprenant des plaques munies de nervures ayant des zones de hauteur maximale |
| US4777953A (en) | 1987-02-25 | 1988-10-18 | Ash Medical Systems, Inc. | Capillary filtration and collection method for long-term monitoring of blood constituents |
| US4832034A (en) | 1987-04-09 | 1989-05-23 | Pizziconi Vincent B | Method and apparatus for withdrawing, collecting and biosensing chemical constituents from complex fluids |
| WO1994025875A1 (en) | 1993-04-29 | 1994-11-10 | Danfoss A/S | Device for analyzing a fluid medium |
| DE19612105C2 (de) | 1996-03-27 | 1998-11-05 | Inst Diabetestechnologie Gemei | Verfahren und Anordnung zur Bestimmung der Konzentration eines Metaboliten in Biogewebe |
| SE513034C2 (sv) | 1997-06-02 | 2000-06-19 | Gambro Lundia Ab | Metod och anordning för beräkning av dialyseffektivitet |
| SE511932C2 (sv) | 1998-03-11 | 1999-12-20 | Jan Liska | En metod och en kateter för detektering av substanser |
| DE19941271A1 (de) | 1999-08-31 | 2001-04-05 | Lienhard Pagel | Mikrofluidisches Membranmodul |
| US6284115B1 (en) * | 1999-09-21 | 2001-09-04 | Agilent Technologies, Inc. | In-line flow through micro-dialysis apparatus and method for high performance liquid phase separations |
| US6802820B1 (en) | 2000-04-13 | 2004-10-12 | Transvivo, Inc. | Specialized hollow fiber membranes for in-vivo plasmapheresis and ultrafiltration |
| AT412060B (de) | 2001-07-06 | 2004-09-27 | Schaupp Lukas Dipl Ing Dr Tech | Verfahren zur messung von konzentrationen in lebenden organismen mittels mikrodialyse und und vorrichtung zur durchführung dieses verfahrens |
| WO2004006991A1 (ja) | 2002-07-12 | 2004-01-22 | Kuraray Co., Ltd. | 多孔質膜 |
| SE0203857L (sv) | 2002-12-20 | 2004-06-21 | Gambro Lundia Ab | Permselektivt membran och förfarande för tillverkning därav |
| JP2005224604A (ja) | 2004-01-16 | 2005-08-25 | Asahi Kasei Medical Co Ltd | 血液浄化膜およびそれを用いた血液浄化器 |
| AU2007312413B2 (en) | 2006-10-18 | 2011-09-29 | Gambro Lundia Ab | Hollow fiber membrane and method for manufacturing thereof |
| WO2008048183A1 (en) | 2006-10-18 | 2008-04-24 | Cma/Microdialysis Ab | Microdialysis catheter and a method of making a microdialysis catheter |
| US20100237164A1 (en) | 2007-10-08 | 2010-09-23 | Si Chung Noh | Sprinkler and Method for Controlling the Same |
-
2007
- 2007-10-18 WO PCT/EP2007/009056 patent/WO2008046630A1/en not_active Ceased
- 2007-10-18 EP EP07819121A patent/EP1962993B1/de not_active Not-in-force
- 2007-10-18 US US12/446,234 patent/US8535537B2/en not_active Expired - Fee Related
- 2007-10-18 AT AT07819121T patent/ATE493194T1/de not_active IP Right Cessation
- 2007-10-18 DE DE602007011563T patent/DE602007011563D1/de active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP1962993B1 (de) | 2010-12-29 |
| EP1962993A1 (de) | 2008-09-03 |
| US8535537B2 (en) | 2013-09-17 |
| US20110011786A1 (en) | 2011-01-20 |
| ATE493194T1 (de) | 2011-01-15 |
| WO2008046630A1 (en) | 2008-04-24 |
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