DE602007008953D1 - Qpcr unter verwendung eines ionen-sensitiven feldeffekt-transistors zur ph-messung - Google Patents
Qpcr unter verwendung eines ionen-sensitiven feldeffekt-transistors zur ph-messungInfo
- Publication number
- DE602007008953D1 DE602007008953D1 DE602007008953T DE602007008953T DE602007008953D1 DE 602007008953 D1 DE602007008953 D1 DE 602007008953D1 DE 602007008953 T DE602007008953 T DE 602007008953T DE 602007008953 T DE602007008953 T DE 602007008953T DE 602007008953 D1 DE602007008953 D1 DE 602007008953D1
- Authority
- DE
- Germany
- Prior art keywords
- field effect
- effect transistor
- sensitive field
- qpcr
- measurement
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 230000005669 field effect Effects 0.000 title abstract 2
- 238000001139 pH measurement Methods 0.000 title 1
- 230000003321 amplification Effects 0.000 abstract 2
- 238000003199 nucleic acid amplification method Methods 0.000 abstract 2
- 150000007523 nucleic acids Chemical class 0.000 abstract 2
- 102000039446 nucleic acids Human genes 0.000 abstract 2
- 108020004707 nucleic acids Proteins 0.000 abstract 2
- 238000003752 polymerase chain reaction Methods 0.000 abstract 2
- 238000001514 detection method Methods 0.000 abstract 1
- 238000011002 quantification Methods 0.000 abstract 1
- 238000011897 real-time detection Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6851—Quantitative amplification
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/403—Cells and electrode assemblies
- G01N27/414—Ion-sensitive or chemical field-effect transistors, i.e. ISFETS or CHEMFETS
- G01N27/4145—Ion-sensitive or chemical field-effect transistors, i.e. ISFETS or CHEMFETS specially adapted for biomolecules, e.g. gate electrode with immobilised receptors
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Engineering & Computer Science (AREA)
- Microelectronics & Electronic Packaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Biophysics (AREA)
- Electrochemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Insulated Gate Type Field-Effect Transistor (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/EP2007/052010 WO2008107014A1 (en) | 2007-03-02 | 2007-03-02 | Qpcr using solid-state ph sensing |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE602007008953D1 true DE602007008953D1 (de) | 2010-10-14 |
Family
ID=38353806
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE602007008953T Active DE602007008953D1 (de) | 2007-03-02 | 2007-03-02 | Qpcr unter verwendung eines ionen-sensitiven feldeffekt-transistors zur ph-messung |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP2129792B1 (de) |
| JP (1) | JP5368321B2 (de) |
| CN (1) | CN101743319B (de) |
| AT (1) | ATE479780T1 (de) |
| DE (1) | DE602007008953D1 (de) |
| ES (1) | ES2440572T3 (de) |
| WO (1) | WO2008107014A1 (de) |
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| CN103923998A (zh) * | 2014-04-23 | 2014-07-16 | 浙江大学 | 一种应用于核酸扩增实时电化学pH检测的反应体系和检测方法 |
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| GB0105831D0 (en) * | 2001-03-09 | 2001-04-25 | Toumaz Technology Ltd | Method for dna sequencing utilising enzyme linked field effect transistors |
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| JP2003322630A (ja) * | 2002-05-01 | 2003-11-14 | Seiko Epson Corp | バイオセンサ、バイオセンシングシステム、及びバイオセンシング方法 |
| JP3903183B2 (ja) * | 2004-02-03 | 2007-04-11 | 独立行政法人物質・材料研究機構 | 遺伝子検出電界効果デバイスおよびこれを用いた遺伝子多型解析方法 |
| US7888013B2 (en) * | 2004-08-27 | 2011-02-15 | National Institute For Materials Science | Method of analyzing DNA sequence using field-effect device, and base sequence analyzer |
-
2007
- 2007-03-02 ES ES10174104.9T patent/ES2440572T3/es active Active
- 2007-03-02 WO PCT/EP2007/052010 patent/WO2008107014A1/en not_active Ceased
- 2007-03-02 AT AT07726604T patent/ATE479780T1/de active
- 2007-03-02 JP JP2009551920A patent/JP5368321B2/ja active Active
- 2007-03-02 DE DE602007008953T patent/DE602007008953D1/de active Active
- 2007-03-02 EP EP07726604A patent/EP2129792B1/de active Active
- 2007-03-02 CN CN200780052692.2A patent/CN101743319B/zh active Active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2008107014A1 (en) | 2008-09-12 |
| JP5368321B2 (ja) | 2013-12-18 |
| CN101743319A (zh) | 2010-06-16 |
| ATE479780T1 (de) | 2010-09-15 |
| EP2129792A1 (de) | 2009-12-09 |
| JP2010519914A (ja) | 2010-06-10 |
| ES2440572T3 (es) | 2014-01-29 |
| CN101743319B (zh) | 2013-03-06 |
| EP2129792B1 (de) | 2010-09-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8381 | Inventor (new situation) |
Inventor name: OU, CHUNG-PEI, LONDON SW7 2AZ, GB Inventor name: TOUMAZOU, CHRISTOFER, LONDON SW7 2AZ, GB |