DE602007008759D1 - Pyrroloä1,2-aüimidazoldion zur behandlung von peripherer neurotoxizität durch chemotherapeutische mittel - Google Patents
Pyrroloä1,2-aüimidazoldion zur behandlung von peripherer neurotoxizität durch chemotherapeutische mittelInfo
- Publication number
- DE602007008759D1 DE602007008759D1 DE602007008759T DE602007008759T DE602007008759D1 DE 602007008759 D1 DE602007008759 D1 DE 602007008759D1 DE 602007008759 T DE602007008759 T DE 602007008759T DE 602007008759 T DE602007008759 T DE 602007008759T DE 602007008759 D1 DE602007008759 D1 DE 602007008759D1
- Authority
- DE
- Germany
- Prior art keywords
- pyrroloa1
- aimidazoldion
- treatment
- chemotherapeutic agents
- peripheral neurotoxicity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 206010029350 Neurotoxicity Diseases 0.000 title 1
- 206010044221 Toxic encephalopathy Diseases 0.000 title 1
- 239000002246 antineoplastic agent Substances 0.000 title 1
- 229940127089 cytotoxic agent Drugs 0.000 title 1
- 230000007135 neurotoxicity Effects 0.000 title 1
- 231100000228 neurotoxicity Toxicity 0.000 title 1
- 230000002093 peripheral effect Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4188—1,3-Diazoles condensed with other heterocyclic ring systems, e.g. biotin, sorbinil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Toxicology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06124142A EP1925304A1 (de) | 2006-11-15 | 2006-11-15 | Pyrrolo[1,2-a]imidazoledione zur Behandlung von durch Chemotherapie ausgelöster peripherer Neuropathie |
| PCT/EP2007/062323 WO2008058988A1 (en) | 2006-11-15 | 2007-11-14 | Pyrrolo[1,2-a]imidazoledione effective in the treatment of peripheral neurotoxicity induced by chemotherapeutic agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE602007008759D1 true DE602007008759D1 (de) | 2010-10-07 |
Family
ID=37882430
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE602007008759T Active DE602007008759D1 (de) | 2006-11-15 | 2007-11-14 | Pyrroloä1,2-aüimidazoldion zur behandlung von peripherer neurotoxizität durch chemotherapeutische mittel |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US7973066B2 (de) |
| EP (2) | EP1925304A1 (de) |
| JP (1) | JP2010509389A (de) |
| CN (1) | CN101605541A (de) |
| AR (1) | AR063819A1 (de) |
| AT (1) | ATE478668T1 (de) |
| AU (1) | AU2007321218A1 (de) |
| BR (1) | BRPI0718904A2 (de) |
| CA (1) | CA2669853A1 (de) |
| CL (1) | CL2007003281A1 (de) |
| DE (1) | DE602007008759D1 (de) |
| EA (1) | EA200900552A1 (de) |
| ES (1) | ES2347380T3 (de) |
| IL (1) | IL198689A0 (de) |
| MX (1) | MX2009005125A (de) |
| NZ (1) | NZ576995A (de) |
| PE (1) | PE20081494A1 (de) |
| WO (1) | WO2008058988A1 (de) |
| ZA (1) | ZA200904148B (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITMI20030573A1 (it) * | 2003-03-24 | 2004-09-25 | Nikem Research Srl | Composti ad azione nootropica, loro preparazione, |
| US9125898B2 (en) | 2008-11-14 | 2015-09-08 | Neurotune Ag | Acetam derivatives for pain relief |
| BR112017002060A2 (pt) * | 2014-07-31 | 2017-12-26 | Glaxosmithkline Ip Dev Ltd | novo uso |
| PL4025183T3 (pl) * | 2019-09-02 | 2025-09-22 | Syddansk Universitet | Induktory P-gp do stosowania w ochronie przed skutkami ubocznymi chemioterapii takimi jak neuropatia obwodowa wywołana chemioterapią (CIPN) oraz utrata włosów |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITMI20030573A1 (it) * | 2003-03-24 | 2004-09-25 | Nikem Research Srl | Composti ad azione nootropica, loro preparazione, |
-
2006
- 2006-11-15 EP EP06124142A patent/EP1925304A1/de not_active Withdrawn
-
2007
- 2007-11-13 PE PE2007001562A patent/PE20081494A1/es not_active Application Discontinuation
- 2007-11-14 DE DE602007008759T patent/DE602007008759D1/de active Active
- 2007-11-14 BR BRPI0718904-4A patent/BRPI0718904A2/pt not_active IP Right Cessation
- 2007-11-14 MX MX2009005125A patent/MX2009005125A/es active IP Right Grant
- 2007-11-14 WO PCT/EP2007/062323 patent/WO2008058988A1/en not_active Ceased
- 2007-11-14 EA EA200900552A patent/EA200900552A1/ru unknown
- 2007-11-14 US US12/312,575 patent/US7973066B2/en not_active Expired - Fee Related
- 2007-11-14 NZ NZ576995A patent/NZ576995A/en unknown
- 2007-11-14 CN CNA2007800424416A patent/CN101605541A/zh active Pending
- 2007-11-14 JP JP2009536731A patent/JP2010509389A/ja active Pending
- 2007-11-14 AT AT07847162T patent/ATE478668T1/de not_active IP Right Cessation
- 2007-11-14 AU AU2007321218A patent/AU2007321218A1/en not_active Abandoned
- 2007-11-14 EP EP07847162A patent/EP2094265B1/de active Active
- 2007-11-14 CA CA002669853A patent/CA2669853A1/en not_active Abandoned
- 2007-11-14 AR ARP070105067A patent/AR063819A1/es unknown
- 2007-11-14 ES ES07847162T patent/ES2347380T3/es active Active
- 2007-11-15 CL CL200703281A patent/CL2007003281A1/es unknown
-
2009
- 2009-05-11 IL IL198689A patent/IL198689A0/en unknown
- 2009-06-12 ZA ZA200904148A patent/ZA200904148B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NZ576995A (en) | 2010-12-24 |
| PE20081494A1 (es) | 2008-12-19 |
| ES2347380T3 (es) | 2010-10-28 |
| WO2008058988A1 (en) | 2008-05-22 |
| AR063819A1 (es) | 2009-02-18 |
| BRPI0718904A2 (pt) | 2013-12-10 |
| EP2094265A1 (de) | 2009-09-02 |
| AU2007321218A1 (en) | 2008-05-22 |
| CN101605541A (zh) | 2009-12-16 |
| ATE478668T1 (de) | 2010-09-15 |
| US20100062077A1 (en) | 2010-03-11 |
| CL2007003281A1 (es) | 2008-06-27 |
| EP2094265B1 (de) | 2010-08-25 |
| EP1925304A1 (de) | 2008-05-28 |
| EA200900552A1 (ru) | 2009-10-30 |
| CA2669853A1 (en) | 2008-05-22 |
| ZA200904148B (en) | 2010-04-28 |
| JP2010509389A (ja) | 2010-03-25 |
| US7973066B2 (en) | 2011-07-05 |
| MX2009005125A (es) | 2009-11-02 |
| IL198689A0 (en) | 2010-02-17 |
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