DE602006020052D1 - Neue arzneimittel gegen demenz - Google Patents
Neue arzneimittel gegen demenzInfo
- Publication number
- DE602006020052D1 DE602006020052D1 DE602006020052T DE602006020052T DE602006020052D1 DE 602006020052 D1 DE602006020052 D1 DE 602006020052D1 DE 602006020052 T DE602006020052 T DE 602006020052T DE 602006020052 T DE602006020052 T DE 602006020052T DE 602006020052 D1 DE602006020052 D1 DE 602006020052D1
- Authority
- DE
- Germany
- Prior art keywords
- against damage
- new medicines
- medicines against
- new
- damage
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0205—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)3-C(=0)-, e.g. statine or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Crystallography & Structural Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Hospice & Palliative Care (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US72206605P | 2005-09-28 | 2005-09-28 | |
| US77263106P | 2006-02-10 | 2006-02-10 | |
| PCT/US2006/038387 WO2007038772A1 (en) | 2005-09-28 | 2006-09-28 | Novel drugs for dementia |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE602006020052D1 true DE602006020052D1 (de) | 2011-03-24 |
Family
ID=37708469
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE602006020052T Active DE602006020052D1 (de) | 2005-09-28 | 2006-09-28 | Neue arzneimittel gegen demenz |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20080227806A1 (de) |
| EP (1) | EP1931656B1 (de) |
| DE (1) | DE602006020052D1 (de) |
| WO (1) | WO2007038772A1 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100216875A1 (en) * | 2006-12-20 | 2010-08-26 | Gregory Hook | Methods of treating alzheimer's disease |
| EP2921486B1 (de) | 2009-08-07 | 2017-09-27 | American Life Science Pharmaceuticals, Inc. | Zusammensetzungen und Verfahren zur Behandlung von durch beta-Amyloid vermittelter Erkrankungen |
| US20110105603A1 (en) * | 2010-08-06 | 2011-05-05 | American Life Science Pharmaceuticals, Inc. | Compositions and methods for treating beta-amyloid related diseases |
| JP5934645B2 (ja) | 2009-09-11 | 2016-06-15 | プロビオドルグ エージー | グルタミニルシクラーゼ阻害剤としてのヘテロ環式誘導体 |
| PL3461819T3 (pl) | 2017-09-29 | 2020-11-30 | Probiodrug Ag | Inhibitory cyklazy glutaminylowej |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS55115878A (en) * | 1979-02-27 | 1980-09-06 | Taisho Pharmaceut Co Ltd | Epoxysuccinic acid derivative |
| JPS55153778A (en) * | 1979-05-17 | 1980-11-29 | Taisho Pharmaceut Co Ltd | Epoxysuccinylamino acid derivative |
| US4942165A (en) * | 1986-02-11 | 1990-07-17 | Advanced Biologics, Inc. | Treatment for Alzheimer's disease |
| JP2808877B2 (ja) * | 1990-09-29 | 1998-10-08 | 大正製薬株式会社 | エポキシスクシナム酸誘導体およびその中間体 |
| EP0580161A1 (de) * | 1992-07-22 | 1994-01-26 | THE McLEAN HOSPITAL CORPORATION | Prophylaktische und therapeutische Behandlung der Alzheimer'schen Krankheit |
| US5556853A (en) * | 1993-10-29 | 1996-09-17 | Takeda Chemical Industries, Ltd. | Epoxysuccinic acid derivatives |
| AU2537695A (en) * | 1994-05-31 | 1995-12-21 | Takeda Chemical Industries Ltd. | Epoxysuccinic acid derivatives, their production and use |
| AU716620B2 (en) * | 1995-03-31 | 2000-03-02 | Nippon Chemiphar Co. Ltd. | Epoxysuccinic acid derivatives |
| CA2258354A1 (en) * | 1997-04-18 | 1998-10-29 | Taiho Pharmaceutical Co., Ltd. | Novel epoxysuccinamide derivatives or salts thereof |
| PT1022276E (pt) * | 1997-09-04 | 2003-10-31 | Nippon Chemiphar Co | Derivados de epoxissuccinamida |
| US6313268B1 (en) * | 1998-10-16 | 2001-11-06 | Vivian Y. H. Hook | Secretases related to Alzheimer's dementia |
| WO2004084830A2 (en) * | 2003-03-21 | 2004-10-07 | Buck Institute | Method for treating alzheimer’s dementia |
-
2006
- 2006-09-28 DE DE602006020052T patent/DE602006020052D1/de active Active
- 2006-09-28 WO PCT/US2006/038387 patent/WO2007038772A1/en not_active Ceased
- 2006-09-28 US US12/088,202 patent/US20080227806A1/en not_active Abandoned
- 2006-09-28 EP EP06825333A patent/EP1931656B1/de not_active Not-in-force
Also Published As
| Publication number | Publication date |
|---|---|
| US20080227806A1 (en) | 2008-09-18 |
| EP1931656B1 (de) | 2011-02-09 |
| EP1931656A1 (de) | 2008-06-18 |
| WO2007038772A1 (en) | 2007-04-05 |
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