DE602006001511D1 - Neue 4-aminochinolinderivate als antimalariamittel - Google Patents
Neue 4-aminochinolinderivate als antimalariamittelInfo
- Publication number
- DE602006001511D1 DE602006001511D1 DE602006001511T DE602006001511T DE602006001511D1 DE 602006001511 D1 DE602006001511 D1 DE 602006001511D1 DE 602006001511 T DE602006001511 T DE 602006001511T DE 602006001511 T DE602006001511 T DE 602006001511T DE 602006001511 D1 DE602006001511 D1 DE 602006001511D1
- Authority
- DE
- Germany
- Prior art keywords
- new
- derivatives
- antimalariamidal
- aminochinoline
- chloroquine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- FQYRLEXKXQRZDH-UHFFFAOYSA-N 4-aminoquinoline Chemical class C1=CC=C2C(N)=CC=NC2=C1 FQYRLEXKXQRZDH-UHFFFAOYSA-N 0.000 title 1
- WHTVZRBIWZFKQO-AWEZNQCLSA-N (S)-chloroquine Chemical compound ClC1=CC=C2C(N[C@@H](C)CCCN(CC)CC)=CC=NC2=C1 WHTVZRBIWZFKQO-AWEZNQCLSA-N 0.000 abstract 1
- 150000005011 4-aminoquinolines Chemical class 0.000 abstract 1
- 208000002476 Falciparum Malaria Diseases 0.000 abstract 1
- 201000011336 Plasmodium falciparum malaria Diseases 0.000 abstract 1
- 239000003430 antimalarial agent Substances 0.000 abstract 1
- 229940033495 antimalarials Drugs 0.000 abstract 1
- 229960003677 chloroquine Drugs 0.000 abstract 1
- WHTVZRBIWZFKQO-UHFFFAOYSA-N chloroquine Natural products ClC1=CC=C2C(NC(C)CCCN(CC)CC)=CC=NC2=C1 WHTVZRBIWZFKQO-UHFFFAOYSA-N 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/02—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing not further condensed quinolizine ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05425051 | 2005-02-04 | ||
| PCT/EP2006/000846 WO2006082030A1 (en) | 2005-02-04 | 2006-02-01 | New 4-aminoquinoline derivatives as antimalarials |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE602006001511D1 true DE602006001511D1 (de) | 2008-07-31 |
Family
ID=34943039
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE602006001511T Expired - Fee Related DE602006001511D1 (de) | 2005-02-04 | 2006-02-01 | Neue 4-aminochinolinderivate als antimalariamittel |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20080262031A1 (de) |
| EP (1) | EP1846401B1 (de) |
| AT (1) | ATE398616T1 (de) |
| DE (1) | DE602006001511D1 (de) |
| WO (1) | WO2006082030A1 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090221624A1 (en) * | 2005-05-06 | 2009-09-03 | Olivo Paul D | 4-aminoquinoline compounds for treating virus-related conditions |
| US20120142731A1 (en) * | 2007-10-31 | 2012-06-07 | Functional Genetics, Inc. | Methods of inhibiting viral infection |
| JPWO2015133280A1 (ja) * | 2014-03-03 | 2017-04-06 | 公立大学法人名古屋市立大学 | 抗マラリア活性化合物及び抗マラリア薬 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3553228A (en) * | 1967-09-26 | 1971-01-05 | Colgate Palmolive Co | 3-substituted-4h(1)benzopyrano(3,4-d) isoxazoles |
| US3948928A (en) * | 1972-03-17 | 1976-04-06 | Dainippon Pharmaceutical Co., Ltd. | 3-Substituted-1,2-benzisoxazoles and pharmaceutically acceptable acid addition salts thereof |
| EP0132680B1 (de) * | 1983-07-22 | 1987-01-28 | Bayer Ag | Substituierte Furazane |
| FR2677019B1 (fr) * | 1991-05-27 | 1994-11-25 | Pf Medicament | Nouvelles piperidines disubstituees-1,4, leur preparation et leur application en therapeutique. |
| CA2133620A1 (en) * | 1993-10-28 | 1995-04-29 | Werner Hofheinz | Aminoquinoline derivatives |
| FR2720396B1 (fr) * | 1994-05-27 | 1996-06-28 | Adir | Nouveaux N-pyridyl carboxamides et dérivés leur procédé de préparation et les compositions pharmaceutiques qui les contiennent. |
| WO2001051456A2 (en) * | 2000-01-13 | 2001-07-19 | Tularik Inc. | Antibacterial agents |
| GB0109122D0 (en) * | 2001-04-11 | 2001-05-30 | Smithkline Beecham Spa | Novel compounds |
| US7598287B2 (en) * | 2003-04-01 | 2009-10-06 | Medical College Of Georgia Research Institute, Inc. | Use of inhibitors of indoleamine-2,3-dioxygenase in combination with other therapeutic modalities |
| ITMI20032044A1 (it) * | 2003-10-21 | 2005-04-22 | Univ Degli Studi Milano | Chinolizidinil e chinolizidinilalchil-derivati della 4-ammino-chinolina ad attivita' antimalarica |
| IN2014CN03493A (de) * | 2004-09-08 | 2015-07-03 | Mitsubishi Tanabe Pharma Corp | |
| US7429667B2 (en) * | 2005-01-20 | 2008-09-30 | Ardea Biosciences, Inc. | Phenylamino isothiazole carboxamidines as MEK inhibitors |
| BR122020016659B8 (pt) * | 2005-05-10 | 2021-07-27 | Incyte Holdings Corp | moduladores de 2,3-dioxigenase de indolamina e métodos de modulação de atividade de inibição e de imunossupressão |
| TWI382974B (zh) * | 2005-12-20 | 2013-01-21 | 英塞特公司 | 作為吲哚胺２，３-二氧化酶調節劑之ｎ-羥基甲脒基雜環化物 |
| WO2007095050A2 (en) * | 2006-02-09 | 2007-08-23 | Incyte Corporation | N-hydroxyguanidines as modulators of indoleamine 2,3-dioxygenase |
| CA2663057C (en) * | 2006-09-19 | 2015-12-08 | Incyte Corporation | N-hydroxyamidinoheterocycles as modulators of indoleamine 2,3-dioxygenase |
| WO2008036643A2 (en) * | 2006-09-19 | 2008-03-27 | Incyte Corporation | Amidinoheterocycles as modulators of indoleamine 2,3-dioxygenase |
| US20080146624A1 (en) * | 2006-09-19 | 2008-06-19 | Incyte Corporation | Amidines as modulators of indoleamine 2,3-dioxygenase |
-
2006
- 2006-02-01 US US11/815,366 patent/US20080262031A1/en not_active Abandoned
- 2006-02-01 DE DE602006001511T patent/DE602006001511D1/de not_active Expired - Fee Related
- 2006-02-01 EP EP06706532A patent/EP1846401B1/de not_active Expired - Lifetime
- 2006-02-01 WO PCT/EP2006/000846 patent/WO2006082030A1/en not_active Ceased
- 2006-02-01 AT AT06706532T patent/ATE398616T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| US20080262031A1 (en) | 2008-10-23 |
| EP1846401B1 (de) | 2008-06-18 |
| EP1846401A1 (de) | 2007-10-24 |
| ATE398616T1 (de) | 2008-07-15 |
| WO2006082030A1 (en) | 2006-08-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |