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DE602006001394D1 - Verfahren zur herstellung einer vorstufe von vitamin b1 - Google Patents

Verfahren zur herstellung einer vorstufe von vitamin b1

Info

Publication number
DE602006001394D1
DE602006001394D1 DE200660001394 DE602006001394T DE602006001394D1 DE 602006001394 D1 DE602006001394 D1 DE 602006001394D1 DE 200660001394 DE200660001394 DE 200660001394 DE 602006001394 T DE602006001394 T DE 602006001394T DE 602006001394 D1 DE602006001394 D1 DE 602006001394D1
Authority
DE
Germany
Prior art keywords
preparing vitamin
grewe
hydrolyzing
diamine
hydrolysis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE200660001394
Other languages
English (en)
Inventor
Werner Bonrath
Jocelyn Fischesser
Lisa Giraudi
Reinhard Karge
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DSM IP Assets BV
Original Assignee
DSM IP Assets BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by DSM IP Assets BV filed Critical DSM IP Assets BV
Publication of DE602006001394D1 publication Critical patent/DE602006001394D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE200660001394 2005-01-28 2006-01-24 Verfahren zur herstellung einer vorstufe von vitamin b1 Expired - Lifetime DE602006001394D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05001859 2005-01-28
PCT/EP2006/000600 WO2006079504A2 (en) 2005-01-28 2006-01-24 Process for the manufacture of a precursor of vitamin b1

Publications (1)

Publication Number Publication Date
DE602006001394D1 true DE602006001394D1 (de) 2008-07-17

Family

ID=36118080

Family Applications (1)

Application Number Title Priority Date Filing Date
DE200660001394 Expired - Lifetime DE602006001394D1 (de) 2005-01-28 2006-01-24 Verfahren zur herstellung einer vorstufe von vitamin b1

Country Status (9)

Country Link
US (1) US9108925B2 (de)
EP (1) EP1841745B1 (de)
JP (1) JP5191237B2 (de)
KR (1) KR101277352B1 (de)
CN (1) CN101111484B (de)
AT (1) ATE397593T1 (de)
DE (1) DE602006001394D1 (de)
ES (1) ES2308715T3 (de)
WO (1) WO2006079504A2 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007104442A2 (en) * 2006-03-15 2007-09-20 Dsm Ip Assets B.V. Process for the manufacture of a precursor of vitamin b1
JP5618306B2 (ja) * 2008-07-22 2014-11-05 ディーエスエム アイピー アセッツ ビー．ブイ． 置換４−アミノ−ピリミジンの新規合成
CN103896935B (zh) * 2012-12-27 2016-08-10 江西天新药业有限公司 3-[(4-氨基-5-嘧啶基)甲基]-5-(2-羟乙基)-4-甲基噻唑硝酸盐的制备方法
CN104326989B (zh) * 2014-11-26 2016-04-27 江西天新药业有限公司 2-甲基-4-氨基-5-(氨基甲基)嘧啶的制备方法
US9682216B2 (en) 2014-12-05 2017-06-20 Anchor Endovascular, Inc. Anchor device for use with catheters
CN108546249B (zh) * 2018-02-28 2021-10-01 东北制药集团股份有限公司 一种制备双胺嘧啶的方法
CN109467553B (zh) * 2018-12-24 2021-02-12 江苏兄弟维生素有限公司 一种甲酰嘧啶的提纯方法以及维生素b1合成方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2775592A (en) * 1956-12-25 Z-methyl -
DE2860431D1 (en) * 1977-10-27 1981-02-26 Basf Ag Alpha-aminomethylene-beta-formylaminopropionitrile, process for its preparation and its use in the preparation of 2-methyl-4-amino-5-formylaminomethylpyrimidine
JPS5576084A (en) * 1978-12-01 1980-06-07 Takeda Chem Ind Ltd Method and apparatus for production of vitamin b1 and intermediate thereof
DE3511273A1 (de) * 1985-03-28 1986-10-09 Basf Ag, 6700 Ludwigshafen Verbessertes verfahren zur herstellung von 2-methyl-4-amino-5-aminomethyl-pyrimidin
DE10015470A1 (de) * 2000-03-29 2001-10-11 Basf Ag Verfahren zur Herstellung von 2-Methyl-4-amino-5-aminomethyrimidin

Also Published As

Publication number Publication date
US9108925B2 (en) 2015-08-18
WO2006079504A2 (en) 2006-08-03
US20080242863A1 (en) 2008-10-02
JP2008528529A (ja) 2008-07-31
EP1841745B1 (de) 2008-06-04
ES2308715T3 (es) 2008-12-01
KR101277352B1 (ko) 2013-06-20
ATE397593T1 (de) 2008-06-15
KR20070098888A (ko) 2007-10-05
CN101111484A (zh) 2008-01-23
WO2006079504A3 (en) 2007-02-15
EP1841745A2 (de) 2007-10-10
JP5191237B2 (ja) 2013-05-08
CN101111484B (zh) 2013-07-24

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Legal Events

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