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DE602006004186D1 - VERFAHREN ZUR HERSTELLUNG EINER NICHTAROMATISCHEN L-AMINOSÄURE UNTER VERWENDUNG EINES BAKTERIUMS DERRESSION DES csrA-GENS - Google Patents

VERFAHREN ZUR HERSTELLUNG EINER NICHTAROMATISCHEN L-AMINOSÄURE UNTER VERWENDUNG EINES BAKTERIUMS DERRESSION DES csrA-GENS

Info

Publication number
DE602006004186D1
DE602006004186D1 DE602006004186T DE602006004186T DE602006004186D1 DE 602006004186 D1 DE602006004186 D1 DE 602006004186D1 DE 602006004186 T DE602006004186 T DE 602006004186T DE 602006004186 T DE602006004186 T DE 602006004186T DE 602006004186 D1 DE602006004186 D1 DE 602006004186D1
Authority
DE
Germany
Prior art keywords
bacterium
producing
derression
nonaromatic
csra gene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602006004186T
Other languages
English (en)
Inventor
Andrey Yurievich Gulevich
Danila Vadimovich Zimenkov
Elena Vitalievna Klyachko
Tatyana Viktorovna Leonova
Yury Ivanovich Kozlov
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ajinomoto Co Inc
Original Assignee
Ajinomoto Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from RU2005104459/13A external-priority patent/RU2311453C2/ru
Application filed by Ajinomoto Co Inc filed Critical Ajinomoto Co Inc
Publication of DE602006004186D1 publication Critical patent/DE602006004186D1/de
Anticipated expiration legal-status Critical
Active legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/06—Alanine; Leucine; Isoleucine; Serine; Homoserine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/10—Citrulline; Arginine; Ornithine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/12—Methionine; Cysteine; Cystine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/14—Glutamic acid; Glutamine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/20—Aspartic acid; Asparagine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/24—Proline; Hydroxyproline; Histidine

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE602006004186T 2005-02-18 2006-02-16 VERFAHREN ZUR HERSTELLUNG EINER NICHTAROMATISCHEN L-AMINOSÄURE UNTER VERWENDUNG EINES BAKTERIUMS DERRESSION DES csrA-GENS Active DE602006004186D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
RU2005104459/13A RU2311453C2 (ru) 2005-02-18 2005-02-18 СПОСОБ ПОЛУЧЕНИЯ НЕАРОМАТИЧЕСКИХ L-АМИНОКИСЛОТ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ, ПРИНАДЛЕЖАЩЕЙ К РОДУ ESCHERICHIA, В КОТОРОЙ ИНАКТИВИРОВАН ГЕН csrA
US71485005P 2005-09-08 2005-09-08
PCT/JP2006/303211 WO2006088231A1 (en) 2005-02-18 2006-02-16 A method for producing a non-aromatic l-amino acid using a bacterium of the enterobacteriaceae family having expression of the csra gene attenuated

Publications (1)

Publication Number Publication Date
DE602006004186D1 true DE602006004186D1 (de) 2009-01-22

Family

ID=36293610

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602006004186T Active DE602006004186D1 (de) 2005-02-18 2006-02-16 VERFAHREN ZUR HERSTELLUNG EINER NICHTAROMATISCHEN L-AMINOSÄURE UNTER VERWENDUNG EINES BAKTERIUMS DERRESSION DES csrA-GENS

Country Status (5)

Country Link
US (1) US7771976B2 (de)
EP (1) EP1856269B1 (de)
AT (1) ATE417119T1 (de)
DE (1) DE602006004186D1 (de)
WO (1) WO2006088231A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2004124226A (ru) 2004-08-10 2006-01-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU) Использование фосфокетолазы для продукции полезных метаболитов
US7915018B2 (en) 2004-10-22 2011-03-29 Ajinomoto Co., Inc. Method for producing L-amino acids using bacteria of the Enterobacteriaceae family
EP2186881B1 (de) 2006-03-23 2014-04-23 Ajinomoto Co., Inc. Methode zur Produktion einer L-Aminosäure unter Verwendung eines Bakteriums der Enterobacteriaceae Familie mit einer abgeschwächten Expression eines Gens kodierend für sRNA
EP2066799B1 (de) 2006-09-28 2013-12-11 Ajinomoto Co., Inc. Verfahren zur herstellung von 4-hydroxy-l-isoleucin
RU2396336C2 (ru) 2007-09-27 2010-08-10 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) СПОСОБ ПОЛУЧЕНИЯ АМИНОКИСЛОТ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ, ПРИНАДЛЕЖАЩЕЙ К РОДУ Escherichia
BR112012027293A2 (pt) * 2010-05-20 2015-09-22 Univ Bruxelles processo para aumentar o crescimento de uma célula procariítica, processo para a redução da produção por uma célula, processo para aumentar o teor de glicogénio numa célula, célula recombinante e uso da célula
RU2471870C2 (ru) 2010-06-03 2013-01-10 Закрытое акционерное общество "Научно-исследовательский институт "Аджиномото-Генетика" (ЗАО АГРИ) СПОСОБ ПОЛУЧЕНИЯ L-АРГИНИНА И L-ЦИТРУЛЛИНА С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ СЕМЕЙСТВА ENTEROBACTERIACEAE, В КОТОРОЙ ОСЛАБЛЕНА ЭКСПРЕССИЯ ГЕНА pepA
DE102011078481A1 (de) 2011-06-30 2013-01-03 Wacker Chemie Ag Verfahren zur fermentativen Produktion von natürlichem L-Cystein
US11541105B2 (en) 2018-06-01 2023-01-03 The Research Foundation For The State University Of New York Compositions and methods for disrupting biofilm formation and maintenance
WO2021060438A1 (en) * 2019-09-25 2021-04-01 Ajinomoto Co., Inc. Method for producing l-amino acids by bacterial fermentation
CN112795607B (zh) * 2020-12-31 2023-06-23 河南巨龙生物工程股份有限公司 一种提高腺苷发酵产量的方法

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5976843A (en) * 1992-04-22 1999-11-02 Ajinomoto Co., Inc. Bacterial strain of Escherichia coli BKIIM B-3996 as the producer of L-threonine
US5684144A (en) * 1993-07-28 1997-11-04 University Of North Texas Escherichia coli csrA gene, protein encoded thereby, and methods of use thereof
AU8296298A (en) * 1997-07-11 1999-02-08 University Of North Texas The (escherichia coli csrb) gene, rna encoded thereby, and methods of use thereof
AU5299000A (en) * 1999-05-28 2000-12-18 Tony Romeo A global regulator used to enhance the synthesis of aromatic substances
RU2212447C2 (ru) * 2000-04-26 2003-09-20 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" Штамм escherichia coli - продуцент аминокислоты (варианты) и способ получения аминокислот (варианты)
DE10157721A1 (de) * 2001-11-24 2003-06-05 Degussa Verfahren zur fermentativen Herstellung von nicht aromatischen L-Aminosäuren unter Verwendung von Stämmen der Familie Enterobacteriaceae
RU2244007C2 (ru) 2002-02-27 2005-01-10 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" Способ получения l-треонина, штамм escherichia coli - продуцент треонина (варианты)
RU2273666C2 (ru) 2003-02-26 2006-04-10 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" Способ получения l-аминокислот методом ферментации смеси глюкозы и пентоз
RU2268300C2 (ru) 2003-04-07 2006-01-20 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИЙ, ОБЛАДАЮЩИХ ПОВЫШЕННОЙ ЭКСПРЕССИЕЙ ГЕНА pckA
RU2276687C2 (ru) 2003-07-16 2006-05-20 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" Бактерия, принадлежащая к роду escherichia, - продуцент l-гистидина и способ получения l-гистидина
RU2276688C2 (ru) 2003-08-29 2006-05-20 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" БАКТЕРИЯ, ПРИНАДЛЕЖАЩАЯ К РОДУ Escherichia,- ПРОДУЦЕНТ L-ГИСТИДИНА И СПОСОБ ПОЛУЧЕНИЯ L-ГИСТИДИНА
US20050176033A1 (en) 2003-11-10 2005-08-11 Klyachko Elena V. Mutant phosphoribosylpyrophosphate synthetase and method for producing L-histidine
RU2275424C2 (ru) * 2003-12-05 2006-04-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) Способ получения l-треонина с использованием бактерий, принадлежащих к роду escherichia
US20050191684A1 (en) 2004-02-25 2005-09-01 Zimenkov Danila V. Method for producing L-amino acids
US8003367B2 (en) 2004-03-16 2011-08-23 Ajinomoto Co., Inc. Method for producing L-amino acids by fermentation using bacteria having enhanced expression of xylose utilization genes
RU2306338C2 (ru) 2004-06-24 2007-09-20 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) Mob'-ПРОИЗВОДНАЯ ПЛАЗМИДА RSF1010, НЕ СОДЕРЖАЩАЯ ГЕНЫ УСТОЙЧИВОСТИ К АНТИБИОТИКАМ, БАКТЕРИЯ, СОДЕРЖАЩАЯ УКАЗАННУЮ ПЛАЗМИДУ, И СПОСОБ ПОЛУЧЕНИЯ ПОЛЕЗНЫХ МЕТАБОЛИТОВ
RU2004124226A (ru) 2004-08-10 2006-01-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU) Использование фосфокетолазы для продукции полезных метаболитов
US7915018B2 (en) 2004-10-22 2011-03-29 Ajinomoto Co., Inc. Method for producing L-amino acids using bacteria of the Enterobacteriaceae family
RU2004137198A (ru) * 2004-12-21 2006-06-10 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU) СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ СЕМЕЙСТВА Enterobacteriaceae, В КОТОРОЙ ИНАКТИВИРОВАН ГЕН yafA
RU2004137719A (ru) * 2004-12-23 2006-06-10 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU) Способ получения l-аминокислот с использованием бактерий семейства enterobacteriaceae
US7422880B2 (en) * 2005-01-19 2008-09-09 Ajinomoto Co., Inc. Method for producing an l-amino acid using a bacterium of the enterobacteriaceae family having a pathway of glycogen biosynthesis disrupted

Also Published As

Publication number Publication date
EP1856269A1 (de) 2007-11-21
EP1856269B1 (de) 2008-12-10
WO2006088231A1 (en) 2006-08-24
ATE417119T1 (de) 2008-12-15
US7771976B2 (en) 2010-08-10
US20090239266A1 (en) 2009-09-24

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