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DE602005026854D1 - Verfahren zur herstellung von hohen niveaus von interferon-beta - Google Patents

Verfahren zur herstellung von hohen niveaus von interferon-beta

Info

Publication number
DE602005026854D1
DE602005026854D1 DE602005026854T DE602005026854T DE602005026854D1 DE 602005026854 D1 DE602005026854 D1 DE 602005026854D1 DE 602005026854 T DE602005026854 T DE 602005026854T DE 602005026854 T DE602005026854 T DE 602005026854T DE 602005026854 D1 DE602005026854 D1 DE 602005026854D1
Authority
DE
Germany
Prior art keywords
interferon
beta
high levels
producing high
fermentation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE602005026854T
Other languages
English (en)
Inventor
Sanjeev K Mendiratta
Vibhor Saraswat
Dharmedra Chudasama
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zydus Lifesciences Ltd
Original Assignee
Cadila Healthcare Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cadila Healthcare Ltd filed Critical Cadila Healthcare Ltd
Publication of DE602005026854D1 publication Critical patent/DE602005026854D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/565—IFN-beta
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE602005026854T 2004-12-20 2005-12-19 Verfahren zur herstellung von hohen niveaus von interferon-beta Expired - Lifetime DE602005026854D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1370MU2004 2004-12-20
PCT/IN2005/000419 WO2006067804A2 (en) 2004-12-20 2005-12-19 Process for preparing high levels of interferon beta

Publications (1)

Publication Number Publication Date
DE602005026854D1 true DE602005026854D1 (de) 2011-04-21

Family

ID=36602159

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602005026854T Expired - Lifetime DE602005026854D1 (de) 2004-12-20 2005-12-19 Verfahren zur herstellung von hohen niveaus von interferon-beta

Country Status (14)

Country Link
US (1) US7923220B2 (de)
EP (1) EP1828242B1 (de)
JP (1) JP4705113B2 (de)
KR (1) KR101128055B1 (de)
AT (1) ATE501168T1 (de)
AU (1) AU2005317574B2 (de)
BR (1) BRPI0518491A2 (de)
CA (1) CA2591235C (de)
DE (1) DE602005026854D1 (de)
DK (1) DK1828242T3 (de)
EA (1) EA013263B1 (de)
NZ (1) NZ555979A (de)
WO (1) WO2006067804A2 (de)
ZA (1) ZA200704732B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0707078A2 (pt) * 2006-03-06 2011-04-19 Cadila Healthcare Ltd processo aperfeiçoado para a obtenção de elevados rendimentos volumétricos do fator de estimulação de colÈnia de granulócito ( g- csf) em fermentação em um caldo de cultura
KR101857825B1 (ko) 2010-03-04 2018-05-14 피페넥스 인크. 변성 없이 가용성 재조합 인터페론 단백질을 제조하는 방법

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2108510B (en) * 1981-10-03 1984-12-12 Ciba Geigy Ag Dnas, recombinant dnas, hosts containing them, polypeptides and processes for the production thereof
EP0152483B1 (de) * 1983-08-22 1989-03-29 Kyowa Hakko Kogyo Co., Ltd. Verfahren zur herstellung von peptiden
US4656132A (en) * 1984-03-28 1987-04-07 Cetus Corporation Method of improving the yield of heterologous protein produced by cultivating recombinant bacteria
SU1703692A1 (ru) * 1987-02-09 1992-01-07 Всесоюзный научно-исследовательский институт генетики и селекции промышленных микроорганизмов Рекомбинантна плазмидна ДНК @ -1 @ 1-13, кодирующа синтез фибробластного интерферона ( @ I) человека, способ ее конструировани , штамм бактерий ЕSснеRIснIа coLI - продуцент @ I-интерферона человека
US5462860A (en) * 1994-06-06 1995-10-31 Minnesota Mining And Manufacturing Company Conditioned culture medium for rapid growth and detection of microbes

Also Published As

Publication number Publication date
ATE501168T1 (de) 2011-03-15
CA2591235C (en) 2014-03-11
KR20070091334A (ko) 2007-09-10
ZA200704732B (en) 2009-08-26
AU2005317574B2 (en) 2011-11-03
JP4705113B2 (ja) 2011-06-22
KR101128055B1 (ko) 2012-03-29
NZ555979A (en) 2009-04-30
US20090215121A1 (en) 2009-08-27
BRPI0518491A2 (pt) 2008-11-25
US7923220B2 (en) 2011-04-12
EA200701105A1 (ru) 2007-12-28
EP1828242B1 (de) 2011-03-09
EA013263B1 (ru) 2010-04-30
EP1828242A2 (de) 2007-09-05
WO2006067804A2 (en) 2006-06-29
DK1828242T3 (da) 2011-04-04
CA2591235A1 (en) 2006-06-29
JP2008523801A (ja) 2008-07-10
AU2005317574A1 (en) 2006-06-29
WO2006067804A3 (en) 2006-12-14

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