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DE602005001873D1 - Amorphe 3-Pyridyl-1-Hydroxyethyliden-1,1-Bisphosphonsäure Mononatriumsalz und Verfahren zu deren Herstellung - Google Patents

Amorphe 3-Pyridyl-1-Hydroxyethyliden-1,1-Bisphosphonsäure Mononatriumsalz und Verfahren zu deren Herstellung

Info

Publication number
DE602005001873D1
DE602005001873D1 DE602005001873T DE602005001873T DE602005001873D1 DE 602005001873 D1 DE602005001873 D1 DE 602005001873D1 DE 602005001873 T DE602005001873 T DE 602005001873T DE 602005001873 T DE602005001873 T DE 602005001873T DE 602005001873 D1 DE602005001873 D1 DE 602005001873D1
Authority
DE
Germany
Prior art keywords
hydroxyethylidene
pyridyl
amorphous
preparation
monosodium salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE602005001873T
Other languages
English (en)
Other versions
DE602005001873T2 (de
Inventor
Stefano Turchetta
Pietro Massardo
Umberto Ciambecchini
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chemi SpA
Original Assignee
Chemi SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from ITMI20040403 external-priority patent/ITMI20040403A1/it
Application filed by Chemi SpA filed Critical Chemi SpA
Publication of DE602005001873D1 publication Critical patent/DE602005001873D1/de
Application granted granted Critical
Publication of DE602005001873T2 publication Critical patent/DE602005001873T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3839—Polyphosphonic acids
    • C07F9/3873—Polyphosphonic acids containing nitrogen substituent, e.g. N.....H or N-hydrocarbon group which can be substituted by halogen or nitro(so), N.....O, N.....S, N.....C(=X)- (X =O, S), N.....N, N...C(=X)...N (X =O, S)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576—Six-membered rings
    • C07F9/58—Pyridine rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
DE602005001873T 2004-03-03 2005-02-18 Amorphe 3-Pyridyl-1-Hydroxyethyliden-1,1-Bisphosphonsäure Mononatriumsalz und Verfahren zu deren Herstellung Expired - Lifetime DE602005001873T2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
ITMI20040403 ITMI20040403A1 (it) 2004-03-03 2004-03-03 Sale monosodico dell'acido 3-piridil-1-idrossietiliden-1,1-bifosfonico in forma amorfa e processo per la sua preparazione
ITMI20040403 2004-03-03
US55890804P 2004-04-01 2004-04-01
US558908P 2004-04-01

Publications (2)

Publication Number Publication Date
DE602005001873D1 true DE602005001873D1 (de) 2007-09-20
DE602005001873T2 DE602005001873T2 (de) 2008-04-24

Family

ID=34751872

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602005001873T Expired - Lifetime DE602005001873T2 (de) 2004-03-03 2005-02-18 Amorphe 3-Pyridyl-1-Hydroxyethyliden-1,1-Bisphosphonsäure Mononatriumsalz und Verfahren zu deren Herstellung

Country Status (5)

Country Link
US (1) US7858634B2 (de)
EP (1) EP1571152B1 (de)
CA (1) CA2498177A1 (de)
DE (1) DE602005001873T2 (de)
ES (1) ES2289650T3 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL213481B1 (pl) † 2004-02-26 2013-03-29 Zentiva As Amorficzne postaci rizedronianu monosodowego, sposób wytwarzania i preparat farmaceutyczny
GB0519891D0 (en) * 2005-09-30 2005-11-09 Pliva Hrvatska D O O Pharmaceutically acceptable salts and hydrates
JP5354858B2 (ja) * 2006-05-09 2013-11-27 株式会社Ａｄｅｋａ スルホンアミド化合物の金属塩を含有するポリエステル樹脂組成物
BRPI0710421A2 (pt) 2006-05-11 2011-08-09 Ind Swift Ltd processo para a preparação de ácido risedrÈnico puro ou sais
KR100812528B1 (ko) 2007-04-12 2008-03-12 보령제약 주식회사 리세드로네이트 나트륨염의 헤미펜타히드레이트의 선택적결정화방법
WO2009050731A2 (en) * 2007-06-20 2009-04-23 Alkem Laboratories Ltd Novel process for preparing risedronic acid

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL77243A (en) * 1984-12-21 1996-11-14 Procter & Gamble Pharmaceutical compositions containing geminal diphosphonic acid compounds and certain such novel compounds
US5368587A (en) * 1993-05-14 1994-11-29 Akzo Nobel N.V. Ampule shield
US5756737A (en) 1993-09-10 1998-05-26 Recordati S.A. Chemical And Pharmaceutical Company Process for the preparation of 9-(2-hydroxy)-ethoxymethyl-guanine
IT1308629B1 (it) 1999-02-23 2002-01-09 Recordati Chem Pharm Processo per la produzione di paroxetina.
ITMI20010773A1 (it) 2001-04-11 2002-10-11 Chemi Spa Processo per la produzione di ioexolo ad elevata purezza
GB2383042A (en) * 2001-10-18 2003-06-18 Cipla Ltd Amorphous alendronate sodium
KR20040101447A (ko) * 2002-04-11 2004-12-02 테바 파마슈티컬 인더스트리즈 리미티드 리세드로네이트 나트륨의 신규한 동질이상체 및유사동질이상체
ITMI20020908A1 (it) 2002-04-29 2003-10-29 Chemi Spa Processo di preparazione di sodio alendronato
ATE327233T1 (de) 2002-12-23 2006-06-15 Chemi Spa Verfahren zur herstellung von sulfinylderivaten mittels oxidation der entsprechenden sulfide
US20050142185A1 (en) * 2003-12-29 2005-06-30 Beleno Alfredo B. Softgel formulations of bisphosphonates bone resorption inhibitors
PL213481B1 (pl) 2004-02-26 2013-03-29 Zentiva As Amorficzne postaci rizedronianu monosodowego, sposób wytwarzania i preparat farmaceutyczny
ITMI20041920A1 (it) 2004-10-11 2005-01-11 Chemi Spa Processo per la preparazione di n, n-diisopropil-3-2-idrossi-5-metilfenil-3-fenil-propabammina
ITMI20050247A1 (it) 2005-02-18 2006-08-19 Chemi Spa Processo per la preparazione di montelukast
US7241805B2 (en) 2005-06-27 2007-07-10 Biovail Laboratories, Inc. Modified release formulations of a bupropion salt

Also Published As

Publication number Publication date
EP1571152B1 (de) 2007-08-08
ES2289650T3 (es) 2008-02-01
EP1571152A1 (de) 2005-09-07
US20050215793A1 (en) 2005-09-29
US7858634B2 (en) 2010-12-28
DE602005001873T2 (de) 2008-04-24
CA2498177A1 (en) 2005-09-03

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