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DE60142615D1 - Epitop-synchronisierung in antigen präsentierenden zellen - Google Patents

Epitop-synchronisierung in antigen präsentierenden zellen

Info

Publication number
DE60142615D1
DE60142615D1 DE60142615T DE60142615T DE60142615D1 DE 60142615 D1 DE60142615 D1 DE 60142615D1 DE 60142615 T DE60142615 T DE 60142615T DE 60142615 T DE60142615 T DE 60142615T DE 60142615 D1 DE60142615 D1 DE 60142615D1
Authority
DE
Germany
Prior art keywords
housekeeping
disclosed
cells
presenting cells
epitop
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60142615T
Other languages
English (en)
Inventor
John J Simard
David C Diamond
Xiang-Dong Lei
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mannkind Corp
Original Assignee
Mannkind Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/561,074 external-priority patent/US6861234B1/en
Application filed by Mannkind Corp filed Critical Mannkind Corp
Application granted granted Critical
Publication of DE60142615D1 publication Critical patent/DE60142615D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515Animal cells
    • A61K2039/5158Antigen-pulsed cells, e.g. T-cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53DNA (RNA) vaccination
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55561CpG containing adjuvants; Oligonucleotide containing adjuvants
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pyrane Compounds (AREA)
DE60142615T 2000-04-28 2001-04-27 Epitop-synchronisierung in antigen präsentierenden zellen Expired - Lifetime DE60142615D1 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US56157200A 2000-04-28 2000-04-28
US56046500A 2000-04-28 2000-04-28
US56157100A 2000-04-28 2000-04-28
US09/561,074 US6861234B1 (en) 2000-04-28 2000-04-28 Method of epitope discovery
PCT/US2001/013806 WO2001082963A2 (en) 2000-04-28 2001-04-27 Method of identifying and producing antigen peptides and use thereof as vaccines

Publications (1)

Publication Number Publication Date
DE60142615D1 true DE60142615D1 (de) 2010-09-02

Family

ID=27504814

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60142615T Expired - Lifetime DE60142615D1 (de) 2000-04-28 2001-04-27 Epitop-synchronisierung in antigen präsentierenden zellen

Country Status (12)

Country Link
US (1) US20070269464A1 (de)
EP (4) EP2278023A1 (de)
JP (1) JP2003535824A (de)
CN (1) CN1440462A (de)
AT (1) ATE474931T1 (de)
AU (3) AU5741001A (de)
CA (1) CA2405363A1 (de)
DE (1) DE60142615D1 (de)
DK (1) DK1276896T3 (de)
ES (1) ES2347762T3 (de)
NZ (1) NZ521715A (de)
WO (1) WO2001082963A2 (de)

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US20030215425A1 (en) * 2001-12-07 2003-11-20 Simard John J. L. Epitope synchronization in antigen presenting cells
US6773695B2 (en) 2000-10-05 2004-08-10 Mannkind Corporation Modulation of allergic response
EP1372736A4 (de) * 2001-03-07 2004-11-17 Mannkind Corp Präparate gegen gefässneubildung bei krebs
EP1595548A3 (de) * 2001-03-07 2006-02-22 Mannkind Corporation Anti-Neovaskulatur Präparationen zur Krebsbehandlung
WO2003008537A2 (en) * 2001-04-06 2003-01-30 Mannkind Corporation Epitope sequences
EP1752160A3 (de) 2001-04-06 2007-05-30 Mannkind Corporation Epitop-Sequenzen
ATE494387T1 (de) 2001-11-07 2011-01-15 Mannkind Corp Für epitope von antigenen kodierende expressionsvektoren und verfahren zu deren konzeption
AU2008229888B2 (en) * 2001-11-07 2012-07-05 Mannkind Corporation Expression vectors encoding epitopes of target-associated antigens and methods for their design
EP1545610A4 (de) * 2002-09-06 2006-11-08 Mannkind Corp Epitop-sequenzen
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HUE043042T2 (hu) * 2013-11-01 2019-07-29 Pfizer Vektorok prosztatához kapcsolódó antigének expressziójára
CN104761644A (zh) * 2014-01-03 2015-07-08 百奇生物科技(苏州)有限公司 大肠杆菌表达的融合蛋白mbp-mart-1及其制备和应用
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JP7026613B2 (ja) 2015-08-07 2022-02-28 イマジナブ・インコーポレーテッド 標的分子に対する抗原結合コンストラクト
CN105175498A (zh) * 2015-10-09 2015-12-23 深圳市康尔诺生物技术有限公司 一种宫颈癌相关的热休克蛋白复合物及其应用
WO2017096247A1 (en) 2015-12-04 2017-06-08 Mayo Foundation For Medical Education And Research Methods and vaccines for inducing immune responses to multiple different mhc molecules
TWI752930B (zh) * 2015-12-23 2022-01-21 德商梅迪基因免疫治療公司 抗原特異性tcr的新生成
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Also Published As

Publication number Publication date
CN1440462A (zh) 2003-09-03
AU2010251790B2 (en) 2013-02-07
EP2278023A1 (de) 2011-01-26
HK1053333A1 (en) 2003-10-17
ES2347762T3 (es) 2010-11-04
US20070269464A1 (en) 2007-11-22
DK1276896T3 (da) 2010-10-18
AU2010251790A1 (en) 2011-01-06
WO2001082963A2 (en) 2001-11-08
NZ521715A (en) 2008-01-31
WO2001082963A3 (en) 2002-04-11
EP2278024A1 (de) 2011-01-26
AU2001257410B9 (en) 2006-10-05
ATE474931T1 (de) 2010-08-15
AU2001257410B8 (en) 2006-12-21
AU2001257410B2 (en) 2006-08-24
EP2248910A1 (de) 2010-11-10
JP2003535824A (ja) 2003-12-02
CA2405363A1 (en) 2001-11-08
EP1276896A2 (de) 2003-01-22
AU5741001A (en) 2001-11-12
EP1276896B1 (de) 2010-07-21

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