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DE60140069D1 - Funktion eines haptoglobin-hämoglobin-rezeptors und anwendungszwecke dafür - Google Patents

Funktion eines haptoglobin-hämoglobin-rezeptors und anwendungszwecke dafür

Info

Publication number
DE60140069D1
DE60140069D1 DE60140069T DE60140069T DE60140069D1 DE 60140069 D1 DE60140069 D1 DE 60140069D1 DE 60140069 T DE60140069 T DE 60140069T DE 60140069 T DE60140069 T DE 60140069T DE 60140069 D1 DE60140069 D1 DE 60140069D1
Authority
DE
Germany
Prior art keywords
function
haptoglobin
hemoglobin receptor
application therefor
receptor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60140069T
Other languages
English (en)
Inventor
Soren Moestrup
Holger J Moller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CYTOGUIDE APS
Original Assignee
CYTOGUIDE APS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CYTOGUIDE APS filed Critical CYTOGUIDE APS
Application granted granted Critical
Publication of DE60140069D1 publication Critical patent/DE60140069D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/72Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
    • G01N33/721Haemoglobin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/6445Haemoglobin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70596Molecules with a "CD"-designation not provided for elsewhere
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/795Porphyrin- or corrin-ring-containing peptides
    • C07K14/805Haemoglobins; Myoglobins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE60140069T 2000-10-16 2001-10-12 Funktion eines haptoglobin-hämoglobin-rezeptors und anwendungszwecke dafür Expired - Lifetime DE60140069D1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DKPA200001543 2000-10-16
DKPA200100039 2001-01-11
US27012001P 2001-02-22 2001-02-22
PCT/DK2001/000671 WO2002032941A2 (en) 2000-10-16 2001-10-12 The function of a haptoglobin-haemoglobin receptor and the uses thereof

Publications (1)

Publication Number Publication Date
DE60140069D1 true DE60140069D1 (de) 2009-11-12

Family

ID=27222446

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60140069T Expired - Lifetime DE60140069D1 (de) 2000-10-16 2001-10-12 Funktion eines haptoglobin-hämoglobin-rezeptors und anwendungszwecke dafür

Country Status (10)

Country Link
US (3) US20020155995A1 (de)
EP (1) EP1328297B1 (de)
AT (1) ATE444082T1 (de)
AU (1) AU2002210383A1 (de)
CY (1) CY1110579T1 (de)
DE (1) DE60140069D1 (de)
DK (1) DK1328297T3 (de)
ES (1) ES2334103T3 (de)
PT (1) PT1328297E (de)
WO (1) WO2002032941A2 (de)

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WO2002032941A2 (en) 2000-10-16 2002-04-25 Proteopharma Aps The function of a haptoglobin-haemoglobin receptor and the uses thereof
NZ528832A (en) 2001-03-26 2008-08-29 Hemosol Lp Blood cell production via activation of the hemoglobin scavenger receptor
EP1367393A1 (de) * 2002-05-27 2003-12-03 MacroZyme B.V. Verfahren zur Verwendung des CD 163 Wegs zur Modulation einer Immunantwort
WO2003100419A1 (en) * 2002-05-27 2003-12-04 Bioceros B.V. Methods for using the cd163 pathway for modulating an immune response
GB0423196D0 (en) * 2004-10-19 2004-11-24 Nat Blood Authority Method
US8273538B2 (en) * 2006-05-26 2012-09-25 Temple University Of The Commonwealth System Of Higher Education Blood monocyte CD163 expression as a biomarker in HIV-1 infection and neuroaids
US20080293623A1 (en) * 2007-04-30 2008-11-27 Nhs Blood And Transplant Enriched haptoglobin polymers for the treatment of disease
GB0917054D0 (en) 2009-09-29 2009-11-11 Cytoguide As Agents, uses and methods
GB0917044D0 (en) * 2009-09-29 2009-11-18 Cytoguide As Agents, uses and methods
EP2488863A2 (de) 2009-10-12 2012-08-22 Aarhus Universitet Prognoseverfahren
GB201122325D0 (en) 2011-12-23 2012-02-01 Cytoguide As Novel formulations
CN110256571A (zh) * 2018-11-30 2019-09-20 莱尔芙高新技术(上海)有限公司 重组人白蛋白-血红蛋白β亚基融合蛋白
EP3715374A1 (de) 2019-03-23 2020-09-30 Ablevia biotech GmbH Verbindung zur sequestrierung von unerwünschten antikörpern in einem patienten
US11986536B2 (en) 2019-03-23 2024-05-21 Ablevia Biotech Gmbh Compound for the sequestration of undesirable antibodies in a patient
EP3972646A4 (de) * 2019-05-20 2023-06-14 Ohio State Innovation Foundation Apohämoglobin-haptoglobin-komplexe und verfahren zur verwendung davon
EP4004051A4 (de) 2019-07-19 2023-08-23 Oncoresponse, Inc. Immunmodulatorische antikörper und verfahren zur verwendung davon
KR102254246B1 (ko) * 2020-03-23 2021-05-20 큐벳 주식회사 항-cd163 항체 또는 이의 항원 결합 단편을 인코딩하는 핵산 분자 및 이를 포함하는 아데노바이러스 벡터, 및 이의 아프리카 돼지열병의 예방 또는 치료용도
US20230365655A1 (en) 2020-09-23 2023-11-16 Ablevia Biotech Gmbh Compound for increasing the efficacy of factor viii replacement therapy
MX2023003376A (es) 2020-09-23 2023-03-31 Ablevia Biotech Gmbh Compuesto para la prevencion o el tratamiento de afecciones mediadas por autoanticuerpos.
TW202228784A (zh) 2020-09-23 2022-08-01 奧地利商艾柏力維亞生技有限公司 用以於一患者中螯合非預期的抗peg抗體的化合物
EP4216990A1 (de) 2020-09-23 2023-08-02 Ablevia biotech GmbH Verbindung zur sequestrierung von unerwünschten antikörpern in einem patienten
EP4217006A1 (de) 2020-09-23 2023-08-02 Ablevia biotech GmbH Verbindung zur erhöhung der wirksamkeit von viralen vektoren
CN116710143A (zh) 2020-09-24 2023-09-05 艾柏力维亚生技有限公司 用于预防或治疗重症肌无力的化合物
AU2021418225A1 (en) * 2021-01-05 2023-07-13 Public University Corporation Yokohama City University Biomarker for determining fertility, and determining method using same
EP4499132A1 (de) 2022-03-24 2025-02-05 Ablevia biotech GmbH Verbindung zur erhöhung der wirksamkeit von onkolytischen viren
EP4655324A1 (de) 2023-01-27 2025-12-03 Vib Vzw Cd163-bindende konjugate

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US4177A (en) * 1845-09-02 Phineas bennet
US41177A (en) * 1864-01-05 Tiios
US4061735A (en) * 1973-11-15 1977-12-06 The Green Cross Corporation Haptoglobin in aqueous solution and process for preparing the same
JPS52128205A (en) * 1976-04-16 1977-10-27 Green Cross Corp:The Prophylactic and therapeutic drugs for cerebro-vascular contraction
US5155020A (en) 1989-03-08 1992-10-13 Health Research Inc. Recombinant poxvirus host range selection system
US4769330A (en) 1981-12-24 1988-09-06 Health Research, Incorporated Modified vaccinia virus and methods for making and using the same
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US5204243A (en) 1990-02-14 1993-04-20 Health Research Incorporated Recombinant poxvirus internal cores
US5252348A (en) 1990-10-19 1993-10-12 Univ. Of Florida Research Foundation, Inc. Artificial viral envelopes
JPH11505505A (ja) 1994-06-27 1999-05-21 ザ・ジョンズ・ホプキンス・ユニバーシティー ターゲッティングされた遺伝子輸送システム
US5691197A (en) 1995-02-21 1997-11-25 Tryggvason; Karl Isolated DNA sequence for a novel macrophage receptor with a collagenous domain
AU711702B2 (en) 1995-03-23 1999-10-21 Cambridge University Technical Services Limited Vectors for gene delivery
KR19990063632A (ko) * 1995-09-21 1999-07-26 디 헤이쓰, 산드라 우드 약물 운송용 트란스사이토시스 매개체 및 상승제
US6479258B1 (en) * 1995-12-07 2002-11-12 Diversa Corporation Non-stochastic generation of genetic vaccines
US5972899A (en) 1996-01-25 1999-10-26 New York University Apoptosis induced by Shigella IpaB
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US6046314A (en) 1997-03-06 2000-04-04 Bristol-Myers Squibb Co. Spα: a novel scavenger receptor cysteine-rich domain-containing polypeptide, and monoclonal antibodies thereto
US5962667A (en) 1997-11-03 1999-10-05 Virginia Commonwealth University Pharmaco-gene delivery in human breast cancer cells
CA2236344A1 (en) * 1998-04-30 1999-10-30 Hemosol Inc. Hemoglobin-haptoglobin complexes
DK1281083T3 (da) * 2000-03-28 2007-10-22 Dartmouth College Fremgangsmåde til detektering af inflammation og inflammatoriske tilstande
WO2002032941A2 (en) 2000-10-16 2002-04-25 Proteopharma Aps The function of a haptoglobin-haemoglobin receptor and the uses thereof
GB0917044D0 (en) * 2009-09-29 2009-11-18 Cytoguide As Agents, uses and methods

Also Published As

Publication number Publication date
CY1110579T1 (el) 2015-04-29
PT1328297E (pt) 2010-01-04
ATE444082T1 (de) 2009-10-15
US9476890B2 (en) 2016-10-25
DK1328297T3 (da) 2010-02-01
WO2002032941A3 (en) 2002-07-25
WO2002032941A2 (en) 2002-04-25
EP1328297A2 (de) 2003-07-23
ES2334103T3 (es) 2010-03-05
US20020155995A1 (en) 2002-10-24
US20050063951A1 (en) 2005-03-24
US20080242843A1 (en) 2008-10-02
WO2002032941A8 (en) 2004-04-29
AU2002210383A1 (en) 2002-04-29
EP1328297B1 (de) 2009-09-30

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