DE60140950D1 - Neuer gentherapeutischer wirkstoff zur behandlung g - Google Patents
Neuer gentherapeutischer wirkstoff zur behandlung gInfo
- Publication number
- DE60140950D1 DE60140950D1 DE60140950T DE60140950T DE60140950D1 DE 60140950 D1 DE60140950 D1 DE 60140950D1 DE 60140950 T DE60140950 T DE 60140950T DE 60140950 T DE60140950 T DE 60140950T DE 60140950 D1 DE60140950 D1 DE 60140950D1
- Authority
- DE
- Germany
- Prior art keywords
- gene
- therapy
- gentherapeutic
- agent
- treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 108090000623 proteins and genes Proteins 0.000 abstract 7
- 239000003814 drug Substances 0.000 abstract 3
- 229940079593 drug Drugs 0.000 abstract 3
- 238000002560 therapeutic procedure Methods 0.000 abstract 3
- 102100022641 Coagulation factor IX Human genes 0.000 abstract 2
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 2
- 208000009429 hemophilia B Diseases 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 210000000349 chromosome Anatomy 0.000 abstract 1
- 230000035790 physiological processes and functions Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/482—Serine endopeptidases (3.4.21)
- A61K38/4846—Factor VII (3.4.21.21); Factor IX (3.4.21.22); Factor Xa (3.4.21.6); Factor XI (3.4.21.27); Factor XII (3.4.21.38)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Diabetes (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN00113652 | 2000-08-30 | ||
| CNB011028300A CN1148228C (zh) | 2000-08-30 | 2001-01-19 | 治疗血友病b的基因药物及其制备方法 |
| PCT/CN2001/001291 WO2002034296A1 (en) | 2000-08-30 | 2001-08-29 | A novel gene therapy agent for haemophilia b and its preparation method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60140950D1 true DE60140950D1 (de) | 2010-02-11 |
Family
ID=25739400
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60140950T Expired - Lifetime DE60140950D1 (de) | 2000-08-30 | 2001-08-29 | Neuer gentherapeutischer wirkstoff zur behandlung g |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7361639B2 (de) |
| EP (1) | EP1316319B1 (de) |
| JP (1) | JP2004512313A (de) |
| CN (1) | CN1148228C (de) |
| AT (1) | ATE453401T1 (de) |
| AU (1) | AU2002223402A1 (de) |
| DE (1) | DE60140950D1 (de) |
| WO (1) | WO2002034296A1 (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002020802A1 (en) * | 2000-09-04 | 2002-03-14 | Hunan Royal Biotech | A cell line expressing mutant human tissue-type plasminogen activator, constructing strategy and method of expressed protein preparation |
| CN1880458B (zh) * | 2005-06-15 | 2010-04-28 | 中国医学科学院基础医学研究所 | 人β-珠蛋白基因簇的人源染色体打靶载体及其应用 |
| US8980382B2 (en) * | 2009-12-02 | 2015-03-17 | Applied Materials, Inc. | Oxygen-doping for non-carbon radical-component CVD films |
| WO2015143177A1 (en) | 2014-03-21 | 2015-09-24 | The Board Of Trustees Of The Leland Stanford Junior University | Genome editing without nucleases |
| GB201420139D0 (en) | 2014-11-12 | 2014-12-24 | Ucl Business Plc | Factor IX gene therapy |
| CA3064730A1 (en) | 2017-05-22 | 2018-11-29 | Baxalta Incorporated | Viral vectors encoding recombinant fix variants with increased expression for gene therapy of hemophilia b |
| GB201813528D0 (en) | 2018-08-20 | 2018-10-03 | Ucl Business Plc | Factor IX encoding nucleotides |
| US10842885B2 (en) | 2018-08-20 | 2020-11-24 | Ucl Business Ltd | Factor IX encoding nucleotides |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH08511423A (ja) * | 1993-06-10 | 1996-12-03 | ジェネティック セラピー,インコーポレイテッド | 血友病治療のためのアデノウイルスベクター |
| AU6468199A (en) | 1998-09-23 | 2000-04-10 | Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw | Method to treat haemophilia by (in vivo) gene therapy with retroviral vectors |
-
2001
- 2001-01-19 CN CNB011028300A patent/CN1148228C/zh not_active Expired - Fee Related
- 2001-08-29 EP EP01988597A patent/EP1316319B1/de not_active Expired - Lifetime
- 2001-08-29 AU AU2002223402A patent/AU2002223402A1/en not_active Abandoned
- 2001-08-29 US US10/362,916 patent/US7361639B2/en not_active Expired - Fee Related
- 2001-08-29 JP JP2002537347A patent/JP2004512313A/ja active Pending
- 2001-08-29 AT AT01988597T patent/ATE453401T1/de not_active IP Right Cessation
- 2001-08-29 WO PCT/CN2001/001291 patent/WO2002034296A1/zh not_active Ceased
- 2001-08-29 DE DE60140950T patent/DE60140950D1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US20040038919A1 (en) | 2004-02-26 |
| EP1316319B1 (de) | 2009-12-30 |
| EP1316319A4 (de) | 2008-08-06 |
| CN1302664A (zh) | 2001-07-11 |
| JP2004512313A (ja) | 2004-04-22 |
| US7361639B2 (en) | 2008-04-22 |
| AU2002223402A1 (en) | 2002-05-06 |
| CN1148228C (zh) | 2004-05-05 |
| ATE453401T1 (de) | 2010-01-15 |
| WO2002034296A1 (en) | 2002-05-02 |
| EP1316319A1 (de) | 2003-06-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |