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DE60138189D1 - Eine neue verwendung von deferiprone - Google Patents

Eine neue verwendung von deferiprone

Info

Publication number
DE60138189D1
DE60138189D1 DE60138189T DE60138189T DE60138189D1 DE 60138189 D1 DE60138189 D1 DE 60138189D1 DE 60138189 T DE60138189 T DE 60138189T DE 60138189 T DE60138189 T DE 60138189T DE 60138189 D1 DE60138189 D1 DE 60138189D1
Authority
DE
Germany
Prior art keywords
deferiprone
patient
new use
cardiac disease
induced cardiac
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60138189T
Other languages
English (en)
Inventor
Michael Spino
Antonia Piga
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Apotex Inc
Original Assignee
Apotex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=4166629&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE60138189(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Apotex Inc filed Critical Apotex Inc
Application granted granted Critical
Publication of DE60138189D1 publication Critical patent/DE60138189D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE60138189T 2000-06-30 2001-06-28 Eine neue verwendung von deferiprone Expired - Lifetime DE60138189D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CA2313270A CA2313270C (en) 2000-06-30 2000-06-30 Use of deferiprone in treating and preventing iron-induced cardiac disease
PCT/CA2001/000956 WO2002002114A1 (en) 2000-06-30 2001-06-28 A new use for deferiprone

Publications (1)

Publication Number Publication Date
DE60138189D1 true DE60138189D1 (de) 2009-05-14

Family

ID=4166629

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60138189T Expired - Lifetime DE60138189D1 (de) 2000-06-30 2001-06-28 Eine neue verwendung von deferiprone

Country Status (16)

Country Link
US (2) US7049328B2 (de)
EP (1) EP1294379B1 (de)
CN (3) CN101933924A (de)
AT (1) ATE427107T1 (de)
AU (2) AU7040201A (de)
BR (1) BR0112280A (de)
CA (1) CA2313270C (de)
CY (1) CY1109191T1 (de)
DE (1) DE60138189D1 (de)
DK (1) DK1294379T3 (de)
ES (1) ES2324978T3 (de)
HK (1) HK1043316A1 (de)
IL (2) IL153733A0 (de)
PT (1) PT1294379E (de)
WO (1) WO2002002114A1 (de)
ZA (1) ZA200109322B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY151412A (en) * 2006-02-22 2014-05-30 Munnich Arnold The use of deferiprone and methods to treat and/or prevent friedreich ataxia resulting from intracellular mishandling of iron
NZ579928A (en) 2007-03-28 2012-09-28 Apotex Technologies Inc Fluorinated derivatives of deferiprone
AU2008355464C1 (en) * 2008-04-25 2014-11-20 Chiesi Farmaceutici S.P.A. Liquid formulation for deferiprone with palatable taste
KR101682966B1 (ko) 2009-07-03 2016-12-06 아포텍스 테크놀로지스 인크. 3―하이드록시피리딘―4―온의 불소화된 유도체
US9849146B2 (en) 2009-07-20 2017-12-26 Rutgers, The State University Of New Jersey Inhibition of nonsense mediated mRNA decay by drugs that prevent hypusination of eukaryotic initiation factor 5A
US8603814B2 (en) * 2009-07-20 2013-12-10 Rutgers The State University Of New Jersey Method of inhibiting nonsense-mediated mRNA decay
EP2780012A4 (de) * 2011-11-18 2015-07-29 Apotex Technologies Inc Behandlungsverfahren mit deferipron
US20170266174A1 (en) * 2014-08-21 2017-09-21 Collaborative Medicinal Development Llc Compositions and Methods for Extending Lifespan
CA3032837A1 (en) * 2016-08-05 2018-02-08 Abfero Pharmaceuticals, Inc. Dosing regimens for treating metal-mediated conditions
CN106983746A (zh) * 2017-03-23 2017-07-28 武汉联合药业有限责任公司 一种药物组合物及其用途
CA3172668A1 (en) 2017-10-25 2019-05-02 Chiesi Farmaceutici S.P.A. Delayed release deferiprone tablets and methods of using the same
EP3999059A1 (de) * 2019-07-19 2022-05-25 Vifor (International) Ag Ferroportin-inhibitoren zur verwendung in der behandlung von transfusionsabhängiger beta-thalassämie (tdt)
CN114217071B (zh) * 2021-12-01 2023-11-14 柏荣诊断产品（上海）有限公司 一种高特异性透散射一体法铁蛋白胶乳比浊检测试剂盒
US12016850B2 (en) 2022-04-11 2024-06-25 Chiesi Farmaceutici S.P.A. Modified release pharmaceutical formulations comprising deferiprone
US12016851B2 (en) 2022-04-11 2024-06-25 Chiesi Farmaceutici S.P.A. Modified release pharmaceutical formulations comprising deferiprone
AU2023253115A1 (en) 2022-04-11 2024-11-21 Chiesi Farmaceutici S.P.A. Modified release pharmaceutical formulations comprising deferiprone
CN115429881A (zh) * 2022-09-02 2022-12-06 中国医学科学院基础医学研究所 铁螯合剂治疗β-连环蛋白活化突变的肿瘤

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2118176B (en) * 1982-03-24 1985-12-04 Nat Res Dev Pharmaceutical compositions
US5922761A (en) * 1996-09-06 1999-07-13 Medinox, Inc. Methods for in vivo reduction of iron levels and compositions useful therefor

Also Published As

Publication number Publication date
CN101380322A (zh) 2009-03-11
AU2001270402B9 (en) 2006-03-02
US7049328B2 (en) 2006-05-23
ATE427107T1 (de) 2009-04-15
EP1294379A1 (de) 2003-03-26
HK1043316A1 (zh) 2002-09-13
DK1294379T3 (da) 2009-06-02
CN1331971A (zh) 2002-01-23
CA2313270C (en) 2011-09-13
PT1294379E (pt) 2009-05-04
EP1294379B1 (de) 2009-04-01
ZA200109322B (en) 2002-10-21
CN101933924A (zh) 2011-01-05
HK1130422A1 (en) 2009-12-31
CA2313270A1 (en) 2001-12-30
US20060122273A1 (en) 2006-06-08
WO2002002114A1 (en) 2002-01-10
CY1109191T1 (el) 2014-07-02
AU2001270402B2 (en) 2006-02-02
IL153733A (en) 2010-04-29
ES2324978T3 (es) 2009-08-21
US20030158234A1 (en) 2003-08-21
AU7040201A (en) 2002-01-14
IL153733A0 (en) 2003-07-06
BR0112280A (pt) 2003-05-13
CN101380322B (zh) 2015-06-24

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Legal Events

Date Code Title Description
8363 Opposition against the patent