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DE60137847D1 - Eg-vegf nukleinsäuren und polypeptide und verfahren zur deren verwendung - Google Patents

Eg-vegf nukleinsäuren und polypeptide und verfahren zur deren verwendung

Info

Publication number
DE60137847D1
DE60137847D1 DE60137847T DE60137847T DE60137847D1 DE 60137847 D1 DE60137847 D1 DE 60137847D1 DE 60137847 T DE60137847 T DE 60137847T DE 60137847 T DE60137847 T DE 60137847T DE 60137847 D1 DE60137847 D1 DE 60137847D1
Authority
DE
Germany
Prior art keywords
polypeptides
present
methods
vegf
nucleic acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60137847T
Other languages
English (en)
Inventor
Napoleone Ferrara
Colin Watanabe
William I Wood
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genentech Inc
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2000/032678 external-priority patent/WO2001040466A2/en
Application filed by Genentech Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of DE60137847D1 publication Critical patent/DE60137847D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1858—Platelet-derived growth factor [PDGF]
    • A61K38/1866—Vascular endothelial growth factor [VEGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/475—Assays involving growth factors
    • G01N2333/515—Angiogenesic factors; Angiogenin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Vascular Medicine (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
DE60137847T 2000-06-23 2001-06-22 Eg-vegf nukleinsäuren und polypeptide und verfahren zur deren verwendung Expired - Lifetime DE60137847D1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US21363700P 2000-06-23 2000-06-23
US23097800P 2000-09-07 2000-09-07
PCT/US2000/032678 WO2001040466A2 (en) 1999-12-01 2000-12-01 Secreted and transmembrane polypeptides and nucleic acids encoding the same
PCT/US2001/020116 WO2002000711A2 (en) 2000-06-23 2001-06-22 Ev-vegf nucleic acids and polypeptides and methods of use

Publications (1)

Publication Number Publication Date
DE60137847D1 true DE60137847D1 (de) 2009-04-16

Family

ID=26908256

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60137847T Expired - Lifetime DE60137847D1 (de) 2000-06-23 2001-06-22 Eg-vegf nukleinsäuren und polypeptide und verfahren zur deren verwendung

Country Status (13)

Country Link
US (4) US20020172678A1 (de)
EP (2) EP2075334B1 (de)
JP (1) JP5081361B2 (de)
KR (1) KR100871735B1 (de)
CN (2) CN101269214B (de)
AT (1) ATE424458T1 (de)
AU (3) AU2001268714B2 (de)
CA (1) CA2412612C (de)
DE (1) DE60137847D1 (de)
DK (1) DK1294876T3 (de)
ES (1) ES2323569T3 (de)
MX (1) MXPA03000150A (de)
WO (1) WO2002000711A2 (de)

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DE10229379A1 (de) * 2002-06-26 2004-01-29 Schering Ag EG-VEGF Rezeptor Antagonisten
US7696320B2 (en) 2004-08-24 2010-04-13 Domantis Limited Ligands that have binding specificity for VEGF and/or EGFR and methods of use therefor
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JP6320040B2 (ja) * 2013-12-27 2018-05-09 国立大学法人福井大学 抗ｐｒｏｋ１抗体及び抗ｖｅｇｆ抗体併用による大腸癌の治療
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DK1294876T3 (da) 2009-06-02
US20100254999A1 (en) 2010-10-07
HK1059452A1 (en) 2004-07-02
HK1132298A1 (en) 2010-02-19
US8557238B2 (en) 2013-10-15
AU2006252241A1 (en) 2007-01-25
CN1449445B (zh) 2012-07-18
AU2001268714B2 (en) 2006-09-21
EP1294876B1 (de) 2009-03-04
MXPA03000150A (es) 2003-09-22
CA2412612C (en) 2013-04-30
ATE424458T1 (de) 2009-03-15
KR20030011104A (ko) 2003-02-06
US20050064522A1 (en) 2005-03-24
EP1294876A2 (de) 2003-03-26
ES2323569T3 (es) 2009-07-21
JP5081361B2 (ja) 2012-11-28
CN101269214A (zh) 2008-09-24
WO2002000711A2 (en) 2002-01-03
US20070122412A1 (en) 2007-05-31
WO2002000711A3 (en) 2002-06-20
AU6871401A (en) 2002-01-08
US7446168B2 (en) 2008-11-04
CN1449445A (zh) 2003-10-15
KR100871735B1 (ko) 2008-12-03
JP2004511432A (ja) 2004-04-15
EP2075334A1 (de) 2009-07-01
AU2006252241B2 (en) 2010-03-04
US7727536B2 (en) 2010-06-01
CN101269214B (zh) 2013-09-04
EP2075334B1 (de) 2013-11-20

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