DE60129829D1 - Zyklisierte benzamid-neurokinin-antagonisten zur verwendung in therapie - Google Patents
Zyklisierte benzamid-neurokinin-antagonisten zur verwendung in therapieInfo
- Publication number
- DE60129829D1 DE60129829D1 DE60129829T DE60129829T DE60129829D1 DE 60129829 D1 DE60129829 D1 DE 60129829D1 DE 60129829 T DE60129829 T DE 60129829T DE 60129829 T DE60129829 T DE 60129829T DE 60129829 D1 DE60129829 D1 DE 60129829D1
- Authority
- DE
- Germany
- Prior art keywords
- sup
- cycled
- benzamide
- therapy
- neurokinine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- KXDAEFPNCMNJSK-UHFFFAOYSA-N Benzamide Chemical compound NC(=O)C1=CC=CC=C1 KXDAEFPNCMNJSK-UHFFFAOYSA-N 0.000 title 2
- 239000005557 antagonist Substances 0.000 title 1
- 238000002560 therapeutic procedure Methods 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D267/22—Eight-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hospice & Palliative Care (AREA)
- Pulmonology (AREA)
- Heart & Thoracic Surgery (AREA)
- Rheumatology (AREA)
- Child & Adolescent Psychology (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Psychology (AREA)
- Addiction (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Urology & Nephrology (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Hydrogenated Pyridines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0003476 | 2000-09-28 | ||
| SE0003476A SE0003476D0 (sv) | 2000-09-28 | 2000-09-28 | Compounds |
| PCT/SE2001/002100 WO2002026724A1 (en) | 2000-09-28 | 2001-09-27 | Cyclized benzamide neurokinin antagonists for use in therapy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60129829D1 true DE60129829D1 (de) | 2007-09-20 |
| DE60129829T2 DE60129829T2 (de) | 2008-04-30 |
Family
ID=20281199
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60129829T Expired - Fee Related DE60129829T2 (de) | 2000-09-28 | 2001-09-27 | Zyklisierte benzamid-neurokinin-antagonisten zur verwendung in der therapie |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US6924277B2 (de) |
| EP (1) | EP1324992B1 (de) |
| JP (1) | JP2004509954A (de) |
| AT (1) | ATE369348T1 (de) |
| AU (1) | AU2001290480A1 (de) |
| DE (1) | DE60129829T2 (de) |
| ES (1) | ES2288988T3 (de) |
| SE (1) | SE0003476D0 (de) |
| WO (1) | WO2002026724A1 (de) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060030556A1 (en) * | 2004-08-04 | 2006-02-09 | Solvay Pharmaceuticals B.V. | Neurokinin-1 receptor antagonists for the treatment of conditions responsive to testosterone elevation, including testosterone deficiency |
| WO2006013205A1 (en) * | 2004-08-04 | 2006-02-09 | Solvay Pharmaceuticals B.V. | Neurokinin-1 receptor antagonists for the treatment of conditions responsive to testosterone elevation |
| DE102004038134B4 (de) | 2004-08-05 | 2013-07-25 | Johann Wolfgang Goethe-Universität Frankfurt am Main | Multivalente Chelatoren zum Modifizieren und Organisieren von Zielmolekülen, Verfahren zu ihrer Herstellung sowie ihre Verwendung |
| US20060030600A1 (en) * | 2004-08-06 | 2006-02-09 | Patrick Schnider | Dual NK1/NK3 receptor antagonists for the treatment of schizophrenia |
| EP1976495A2 (de) * | 2006-01-06 | 2008-10-08 | Aarhus Universitet | Auf den serotonin-transporter wirkende verbindungen |
| JP2010516731A (ja) | 2007-01-24 | 2010-05-20 | グラクソ グループ リミテッド | ２−メトキシ−５−（５−トリフルオロメチル−テトラゾール−１−イル）−ベンジル］−（２ｓ−フェニル−ピペリジン−３ｓ−イル）−アミンを含む医薬組成物 |
| WO2012061754A2 (en) * | 2010-11-05 | 2012-05-10 | The Broad Institute, Inc. | Compounds and methods for treating autoimmune diseases |
| WO2012173682A2 (en) * | 2011-03-29 | 2012-12-20 | The Broad Institute, Inc. | Compounds and methods for the treatment of isocitrate dehydrognase related diseases |
| ES2672099T3 (es) | 2011-07-04 | 2018-06-12 | Irbm - Science Park S.P.A. | Antagonistas del receptor NK-1 para el tratamiento de la neovascularización corneal |
| TW201427947A (zh) | 2012-10-12 | 2014-07-16 | Lundbeck & Co As H | 環狀胺 |
| TWI598325B (zh) * | 2012-10-12 | 2017-09-11 | Ｈ 朗德貝克公司 | 苯甲醯胺類 |
| CN111918647A (zh) | 2018-02-26 | 2020-11-10 | 圣拉斐尔医院有限公司 | 用于治疗眼痛的nk-1拮抗剂 |
| RU2697414C1 (ru) | 2018-05-11 | 2019-08-14 | Общество с ограниченной ответственностью "АЙ БИ ДИ Терапевтикс" | Новый антагонист тахикининовых рецепторов и его применение |
| US10889571B2 (en) | 2018-09-18 | 2021-01-12 | Terns, Inc. | Substituted benzoimidazoles and imidazo[4,5-c]pyridines for treating certain leukemias |
| WO2021180885A1 (en) | 2020-03-11 | 2021-09-16 | Ospedale San Raffaele S.R.L. | Treatment of stem cell deficiency |
| US20240400582A1 (en) * | 2021-09-30 | 2024-12-05 | Jiangsu Hansoh Pharmaceutical Group Co., Ltd. | Four-membered fused ring compound and preparation method and use thereof |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2935541B2 (ja) * | 1990-06-28 | 1999-08-16 | サントリー株式会社 | 縮合複素環化合物 |
| US5525600A (en) | 1994-11-28 | 1996-06-11 | American Home Products Corporation | (Thiophen-2-yl)-piperidin or tetrahydropyridin carboxamides |
| GB9505084D0 (en) * | 1995-03-14 | 1995-05-03 | Pfizer Ltd | Benzamide derivative |
| US5541179A (en) | 1995-05-02 | 1996-07-30 | American Home Products Corporation | Tropon-2-one piperazine carboxamides as serotonergic agents |
| US5998439A (en) * | 1996-02-21 | 1999-12-07 | Hoescht Marion Roussel, Inc. | Substituted N-methyl-N-(4-(piperidin-1-yl)-2-(aryl)butyl)benzamides useful for the treatment of allergic diseases |
| US5789422A (en) | 1996-10-28 | 1998-08-04 | Schering Corporation | Substituted arylalkylamines as neurokinin antagonists |
| GB9922521D0 (en) * | 1998-10-07 | 1999-11-24 | Zeneca Ltd | Compounds |
| FR2792835B3 (fr) | 1999-04-27 | 2001-05-25 | Sanofi Sa | Utilisation du saredutant pour la preparation de medicaments utiles dans le traitement ou la prevention de l'ensemble des troubles de l'humeur, des troubles de l'adaptation ou des troubles mixtes anxiete-depression |
| JP2003530388A (ja) * | 2000-04-06 | 2003-10-14 | アストラゼネカ・アクチエボラーグ | 医薬として使用するための新規なニューロキニン拮抗薬 |
-
2000
- 2000-09-28 SE SE0003476A patent/SE0003476D0/xx unknown
-
2001
- 2001-09-27 DE DE60129829T patent/DE60129829T2/de not_active Expired - Fee Related
- 2001-09-27 EP EP01970480A patent/EP1324992B1/de not_active Expired - Lifetime
- 2001-09-27 AU AU2001290480A patent/AU2001290480A1/en not_active Abandoned
- 2001-09-27 ES ES01970480T patent/ES2288988T3/es not_active Expired - Lifetime
- 2001-09-27 JP JP2002531108A patent/JP2004509954A/ja active Pending
- 2001-09-27 US US10/381,755 patent/US6924277B2/en not_active Expired - Fee Related
- 2001-09-27 WO PCT/SE2001/002100 patent/WO2002026724A1/en not_active Ceased
- 2001-09-27 AT AT01970480T patent/ATE369348T1/de not_active IP Right Cessation
-
2005
- 2005-04-27 US US11/115,572 patent/US20050192318A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| ATE369348T1 (de) | 2007-08-15 |
| US6924277B2 (en) | 2005-08-02 |
| EP1324992A1 (de) | 2003-07-09 |
| ES2288988T3 (es) | 2008-02-01 |
| JP2004509954A (ja) | 2004-04-02 |
| DE60129829T2 (de) | 2008-04-30 |
| EP1324992B1 (de) | 2007-08-08 |
| US20040029850A1 (en) | 2004-02-12 |
| SE0003476D0 (sv) | 2000-09-28 |
| WO2002026724A1 (en) | 2002-04-04 |
| AU2001290480A1 (en) | 2002-04-08 |
| US20050192318A1 (en) | 2005-09-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PT1263724E (pt) | Novos compostos | |
| SE0101387D0 (sv) | Novel compounds | |
| IS6658A (is) | Ný efnasambönd | |
| SE9902987D0 (sv) | Novel compounds | |
| DE60235083D1 (de) | Substituierte tetracyclin-verbindungen zur behandlung von malaria | |
| NO20024005D0 (no) | Pteridinforbindelser for behandling av psoriasis | |
| DE60226729D1 (de) | Hydroxyalkylaminderivate als beta-secretase-inhibitoren und deren verwendung zur behandlung der alzheimerschen krankheit oder ähnlicher krankheiten | |
| DE60129829D1 (de) | Zyklisierte benzamid-neurokinin-antagonisten zur verwendung in therapie | |
| ATE495187T1 (de) | Dalda-analoge und ihre verwendung | |
| SE0302139D0 (sv) | Novel compounds | |
| BR0315644A (pt) | Piperazinil e diazapanil benzamidas e benzotioamidas | |
| SE9802208D0 (sv) | Novel compounds | |
| SE0101038D0 (sv) | Novel compounds | |
| SE0302756D0 (sv) | Novel Compounds | |
| MXPA04005809A (es) | Inhibidores de proteinas quinasas. | |
| SE0104326D0 (sv) | Therapeutic heterocycles | |
| SE9802209D0 (sv) | Novel compounds | |
| TR200200278T2 (tr) | Kalsilitik bileşimler | |
| SE0102641D0 (sv) | Novel compounds | |
| DE60103034D1 (de) | Neue phenylheteroalkylamin-derivate | |
| DE60114597D1 (de) | Naphthamid-neurokinin antagonisten zur verwendung als medikamente | |
| SE0004827D0 (sv) | Therapeutic compounds | |
| GB0019008D0 (en) | Therapeutic compounds | |
| ATE416162T1 (de) | Naphthamidderivate und deren verwendung | |
| SE0102640D0 (sv) | Novel compounds |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |