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DE60125750D1 - Pharmazeutische formulierung enthaltend trägerkügelchen mit aufgebrachter schicht aus valaciclovir - Google Patents

Pharmazeutische formulierung enthaltend trägerkügelchen mit aufgebrachter schicht aus valaciclovir

Info

Publication number
DE60125750D1
DE60125750D1 DE60125750T DE60125750T DE60125750D1 DE 60125750 D1 DE60125750 D1 DE 60125750D1 DE 60125750 T DE60125750 T DE 60125750T DE 60125750 T DE60125750 T DE 60125750T DE 60125750 D1 DE60125750 D1 DE 60125750D1
Authority
DE
Germany
Prior art keywords
valaciclovir
pharmaceutical formulation
layered
layer
formulation containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60125750T
Other languages
English (en)
Other versions
DE60125750T2 (de
Inventor
Koho Kawamura
Yasuhiro Mishima
Kiyoshi Ohtsuka
Nobuya Sugibayashi
Keiichi Sugisawa
Hitomi Yanagihara
Makio Yasuda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GlaxoSmithKline KK
Original Assignee
GlaxoSmithKline KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GlaxoSmithKline KK filed Critical GlaxoSmithKline KK
Publication of DE60125750D1 publication Critical patent/DE60125750D1/de
Application granted granted Critical
Publication of DE60125750T2 publication Critical patent/DE60125750T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
DE60125750T 2000-04-28 2001-04-27 Pharmazeutische formulierung enthaltend trägerkügelchen mit aufgebrachter schicht aus valaciclovir Expired - Lifetime DE60125750T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0010446.3A GB0010446D0 (en) 2000-04-28 2000-04-28 Pharmaceutical formulation
GB0010446 2000-04-28
PCT/JP2001/003738 WO2001082905A1 (en) 2000-04-28 2001-04-27 Pharmaceutical formulation comprising carrier beads coated with a layer of valaciclovir

Publications (2)

Publication Number Publication Date
DE60125750D1 true DE60125750D1 (de) 2007-02-15
DE60125750T2 DE60125750T2 (de) 2007-10-31

Family

ID=9890736

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60125750T Expired - Lifetime DE60125750T2 (de) 2000-04-28 2001-04-27 Pharmazeutische formulierung enthaltend trägerkügelchen mit aufgebrachter schicht aus valaciclovir

Country Status (11)

Country Link
US (1) US20030108615A1 (de)
EP (1) EP1278515B1 (de)
JP (2) JP4141688B2 (de)
KR (1) KR100803490B1 (de)
AT (1) ATE350021T1 (de)
AU (1) AU781197B2 (de)
CA (1) CA2433897A1 (de)
DE (1) DE60125750T2 (de)
ES (1) ES2280362T3 (de)
GB (1) GB0010446D0 (de)
WO (1) WO2001082905A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20040016202A (ko) * 2002-08-16 2004-02-21 주식회사 제이알팜 쓴맛이 차폐된 히드로코르티손 경구용 약제 조성물 및 그제조방법
US20080008743A1 (en) * 2006-07-06 2008-01-10 Forest Laboratories Holdings Limited Orally Dissolving Formulations of Memantine
JP5405752B2 (ja) * 2007-01-31 2014-02-05 大日本住友製薬株式会社 被覆された薬物含有粒子および該粒子を含む固形製剤
EP2165706A1 (de) 2008-09-18 2010-03-24 BioAlliance Pharma Behandlung von Entzündungsschmerzen der Mundhöhlenschleimhäute unter Verwendung von therapeutischen mukosalen, bioadhäsiven Trägern mit verlängerter Abgabe
US8592434B2 (en) 2009-12-09 2013-11-26 Bioalliance Pharma Sa Mucoadhesive buccal tablets for the treatment of orofacial herpes
EP2335690A1 (de) * 2009-12-09 2011-06-22 BioAlliance Pharma Mukoadhäsive bukkale Tabletten zur Behandlung von orofazialem Herpes
RS57430B1 (sr) * 2009-12-09 2018-09-28 Vectans Pharma Mukoadhezivne bukalne tablete za lečenje orofacijalnog herpesa
US20120149720A1 (en) * 2010-07-30 2012-06-14 Ranbaxy Laboratories Limited Valacyclovir formulations
US8993041B2 (en) * 2012-10-15 2015-03-31 New Jersey Institute Of Technology Taste masked active pharmaceutical powder compositions and processes for making them
EP2968579B1 (de) * 2013-03-13 2020-04-15 Intervet International B.V. Stabile bioaktive substanzen und verfahren zur herstellung
US20180368458A1 (en) * 2016-02-17 2018-12-27 Corr-Jensen Inc. Time release vitamins and minerals in edible oils
GB201716716D0 (en) * 2017-10-12 2017-11-29 Univ Of Hertfordshire Higher Education Corporation Method for coating particles

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US487613A (en) 1892-12-06 Toy wagon
US4874613A (en) * 1987-03-06 1989-10-17 Baker Cummins Pharmaceuticals, Inc. Taste concealing pharmaceutical dosage unit
GB8719367D0 (en) * 1987-08-15 1987-09-23 Wellcome Found Therapeutic compounds
US4938966A (en) * 1988-11-30 1990-07-03 Riker Laboratories, Inc. Controlled release flecainide acetate formulation
DE3903217A1 (de) * 1989-02-03 1990-08-09 Boehringer Ingelheim Vetmed Verfahren zur herstellung fester pharmazeutischer zubereitungen
UA37214C2 (uk) * 1991-01-30 2001-05-15 Дзе Веллкам Фаундейшн Лімітед Таблетки, що диспергуються у воді, та спосіб їх виготовлення
JPH04283520A (ja) * 1991-03-12 1992-10-08 Asahi Chem Ind Co Ltd 球状核および球形顆粒
JP2665858B2 (ja) * 1992-05-30 1997-10-22 日本ヘキスト・マリオン・ルセル株式会社 持効性塩酸オキシブチニン製剤
JPH0826977A (ja) * 1994-07-19 1996-01-30 Tanabe Seiyaku Co Ltd 溶出制御型経口製剤
GB9501178D0 (en) * 1995-01-20 1995-03-08 Wellcome Found Guanine derivative
GB9501127D0 (en) * 1995-01-20 1995-03-08 Wellcome Found Tablet
JPH0971524A (ja) * 1995-09-08 1997-03-18 Fujisawa Pharmaceut Co Ltd 徐放性粒剤およびその製造方法
GB9518465D0 (en) * 1995-09-09 1995-11-08 Smithkline Beecham Seiyaku Kk Pharmaceuticals
ATE254463T1 (de) * 1996-01-19 2003-12-15 Glaxo Group Ltd Verwendung von valaciclovir zur herstellung eines arzneimittels zur behandlung von genitalherpes durch einmal tägliche verabreichung
US6248636B1 (en) * 1998-05-28 2001-06-19 Samsung Electronics Co., Ltd. Method for forming contact holes of semiconductor memory device
JP3466921B2 (ja) * 1998-06-03 2003-11-17 大塚製薬株式会社 味マスキング医薬製剤
JP2000103732A (ja) * 1998-07-28 2000-04-11 Tanabe Seiyaku Co Ltd 腸内適所放出型製剤
JP2000053563A (ja) * 1998-08-07 2000-02-22 Bayer Yakuhin Ltd 苦味がマスクされた速放性細粒剤
WO2000009133A1 (fr) * 1998-08-10 2000-02-24 Asahi Kasei Kogyo Kabushiki Kaisha Preparations orales, a liberation prolongee, a base de chlorhydrate de fasudil
US6248363B1 (en) * 1999-11-23 2001-06-19 Lipocine, Inc. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions

Also Published As

Publication number Publication date
WO2001082905A1 (en) 2001-11-08
EP1278515B1 (de) 2007-01-03
GB0010446D0 (en) 2000-06-14
DE60125750T2 (de) 2007-10-31
CA2433897A1 (en) 2001-11-08
JP4141688B2 (ja) 2008-08-27
ATE350021T1 (de) 2007-01-15
ES2280362T3 (es) 2007-09-16
KR20030011834A (ko) 2003-02-11
JP2003531851A (ja) 2003-10-28
AU781197B2 (en) 2005-05-12
US20030108615A1 (en) 2003-06-12
EP1278515A1 (de) 2003-01-29
JP2006290903A (ja) 2006-10-26
AU5265801A (en) 2001-11-12
KR100803490B1 (ko) 2008-02-14

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