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DE60121767D1 - LIQUID NON-THERMOSENSIBLE MEDIUM FOR THE ANALYSIS OF SPECIALTIES IN A CHANNEL - Google Patents

LIQUID NON-THERMOSENSIBLE MEDIUM FOR THE ANALYSIS OF SPECIALTIES IN A CHANNEL

Info

Publication number
DE60121767D1
DE60121767D1 DE60121767T DE60121767T DE60121767D1 DE 60121767 D1 DE60121767 D1 DE 60121767D1 DE 60121767 T DE60121767 T DE 60121767T DE 60121767 T DE60121767 T DE 60121767T DE 60121767 D1 DE60121767 D1 DE 60121767D1
Authority
DE
Germany
Prior art keywords
medium
analysis
fluid
thermosensible
specialties
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60121767T
Other languages
German (de)
Other versions
DE60121767T2 (en
Inventor
Jean-Louis Viovy
Valessa Barbier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Institut Curie
Original Assignee
Centre National de la Recherche Scientifique CNRS
Institut Curie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre National de la Recherche Scientifique CNRS, Institut Curie filed Critical Centre National de la Recherche Scientifique CNRS
Application granted granted Critical
Publication of DE60121767D1 publication Critical patent/DE60121767D1/en
Publication of DE60121767T2 publication Critical patent/DE60121767T2/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44704—Details; Accessories
    • G01N27/44747—Composition of gel or of carrier mixture
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F120/00—Homopolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride, ester, amide, imide or nitrile thereof
    • C08F120/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F120/52—Amides or imides
    • C08F120/54—Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2/00—Processes of polymerisation
    • C08F2/04—Polymerisation in solution
    • C08F2/10—Aqueous solvent
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F265/00—Macromolecular compounds obtained by polymerising monomers on to polymers of unsaturated monocarboxylic acids or derivatives thereof as defined in group C08F20/00
    • C08F265/10—Macromolecular compounds obtained by polymerising monomers on to polymers of unsaturated monocarboxylic acids or derivatives thereof as defined in group C08F20/00 on to polymers of amides or imides
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F290/00—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups
    • C08F290/02—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups on to polymers modified by introduction of unsaturated end groups
    • C08F290/04—Polymers provided for in subclasses C08C or C08F
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F290/00—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups
    • C08F290/02—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups on to polymers modified by introduction of unsaturated end groups
    • C08F290/04—Polymers provided for in subclasses C08C or C08F
    • C08F290/046—Polymers of unsaturated carboxylic acids or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/10—Acylation
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2810/00—Chemical modification of a polymer
    • C08F2810/30—Chemical modification of a polymer leading to the formation or introduction of aliphatic or alicyclic unsaturated groups
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2810/00—Chemical modification of a polymer
    • C08F2810/40—Chemical modification of a polymer taking place solely at one end or both ends of the polymer backbone, i.e. not in the side or lateral chains

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Electrochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Dispersion Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Investigating Or Analyzing Materials Using Thermal Means (AREA)
  • Peptides Or Proteins (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Absorbent Articles And Supports Therefor (AREA)
  • Safety Valves (AREA)
  • Materials For Medical Uses (AREA)
  • Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
  • Treatments Of Macromolecular Shaped Articles (AREA)

Abstract

An aqueous liquid medium for analyzing, purifying or separating species in an element having walls or for treating the walls of an element. The medium includes at least a polymer consisting of several polymeric segments. The polymer is of the irregular block-copolymer or irregular comb-like polymer type and has on the average at least three junction points between polymeric segments of different chemical or topological nature. The medium may be used in methods for analyzing, purifying or separating species and methods for treating an element to be contacted with a fluid and/or species contained in the fluid during preservation, transport, analysis, purification or separation of the fluid.
DE60121767T 2000-06-30 2001-06-29 Non-thermosensitive medium for the analysis of species in one channel Expired - Lifetime DE60121767T2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0008526 2000-06-30
FR0008526A FR2811083B1 (en) 2000-06-30 2000-06-30 NON-THERMOSENSITIVE LIQUID MEDIUM FOR THE ANALYSIS OF SPECIES WITHIN A CHANNEL
PCT/FR2001/002103 WO2002001218A2 (en) 2000-06-30 2001-06-29 Non-thermosensitive medium for analysing species inside a channel

Publications (2)

Publication Number Publication Date
DE60121767D1 true DE60121767D1 (en) 2006-09-07
DE60121767T2 DE60121767T2 (en) 2007-08-02

Family

ID=8851970

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60121767T Expired - Lifetime DE60121767T2 (en) 2000-06-30 2001-06-29 Non-thermosensitive medium for the analysis of species in one channel

Country Status (10)

Country Link
US (4) US20040084310A1 (en)
EP (1) EP1295113B1 (en)
JP (2) JP2004502172A (en)
AT (1) ATE334386T1 (en)
AU (1) AU2001270725A1 (en)
CA (1) CA2414295C (en)
DE (1) DE60121767T2 (en)
ES (1) ES2269427T3 (en)
FR (1) FR2811083B1 (en)
WO (1) WO2002001218A2 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2811083B1 (en) * 2000-06-30 2002-11-22 Inst Curie NON-THERMOSENSITIVE LIQUID MEDIUM FOR THE ANALYSIS OF SPECIES WITHIN A CHANNEL
WO2003076922A1 (en) * 2002-03-04 2003-09-18 Symyx Technologies, Inc. Copolymers for use in capillary electrophoretic separation media
EP1539846B1 (en) 2002-07-29 2010-09-08 Life Technologies Corporation Graft copolymers, their preparation and use in capillary electrophoresis
AU2003301503A1 (en) * 2003-12-16 2005-07-14 Centre National De La Recherche Scientifique Methods and compositions for assaying mutations in nucleic acids
FR2867479B1 (en) * 2004-03-15 2007-11-02 Commissariat Energie Atomique HIGH MOLECULAR WEIGHT POLYMER BASED ON N, N-DIMETHYLACRYLAMIDE AND MONOMERS FUNCTIONALIZED BY PROBE MOLECULES AND USES THEREOF
FR2886301B1 (en) * 2005-05-25 2010-08-20 Inst Curie NEW PROCESS FOR THE PREPARATION OF WATER-SOLUBLE PEAR COPOLYMERS
US7932339B2 (en) * 2005-05-25 2011-04-26 Centre National De La Recherche Scientifique Method for producing water-soluble comb-shaped copolymers
EP1798291B1 (en) 2005-12-13 2011-05-18 Institut Curie Methods and compositions for assaying mutations and/or large scale alterations in nucleic acids and their uses in diagnosis of genetic diseases and cancers

Family Cites Families (38)

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CA1206666A (en) 1982-02-19 1986-06-24 Samuel Nochumson Copolymer of acrylamide and polysaccharide resin as electrophoretic gel medium
US4504641A (en) 1982-02-19 1985-03-12 Fmc Corporation Polyacrylamide cross-linked with a polysaccharide resin as electrophoretic gel medium
US4542200A (en) 1982-02-19 1985-09-17 Fmc Corporation Polyacrylamide cross-linked with a polysaccharide resin as electrophoretic gel medium
US4496708A (en) * 1983-12-14 1985-01-29 Union Carbide Corporation Water-soluble polyurethane comb polymer production
DE3500180A1 (en) 1985-01-04 1986-07-10 Ernst Prof. Dr. 7400 Tübingen Bayer Graft copolymers from crosslinked polymers and polyoxyethylene, process for their preparation and their use
US4680201A (en) 1985-10-30 1987-07-14 Stellan Hjerten Coating for electrophoresis tube
US5112460A (en) 1986-10-21 1992-05-12 Northeastern University High performance microcapillary gel electrophoresis
US5225491A (en) 1987-05-07 1993-07-06 The B. F. Goodrich Company Comb-shaped copolymers of a macromolecular monomer of polyhaloether with terminal olefinic unsaturation and process
US5055517A (en) * 1988-04-29 1991-10-08 At Biochem Electrophoretic media
US5306501A (en) 1990-05-01 1994-04-26 Mediventures, Inc. Drug delivery by injection with thermoreversible gels containing polyoxyalkylene copolymers
EP0490406A3 (en) * 1990-12-14 1992-08-05 Hewlett-Packard Company Capillary gel electrophoresis columns and methods of preparing the same
DE4230403A1 (en) 1992-09-11 1994-03-17 Studiengesellschaft Kohle Mbh Deactivation of the inner surface of capillaries
US5759369A (en) * 1992-09-24 1998-06-02 The Perkin-Elmer Corporation Viscous electrophoresis polymer medium and method
US5290418A (en) * 1992-09-24 1994-03-01 Applied Biosystems, Inc. Viscous electrophoresis polymer medium and method
DE69316769T2 (en) * 1992-11-05 1998-06-18 Soane Technologies Inc ELECTROFORETIC SEPARATION MEDIA
US5569364A (en) 1992-11-05 1996-10-29 Soane Biosciences, Inc. Separation media for electrophoresis
EP0639592A1 (en) 1993-08-18 1995-02-22 Nippon Shokubai Co., Ltd. Water-soluble graft polymers and production process thereof
US5891313A (en) * 1993-11-23 1999-04-06 The Perkin-Elmer Corp. Entrapment of nucleic acid sequencing template in sample mixtures by entangled polymer networks
AU1254295A (en) * 1993-12-17 1995-07-03 Perkin-Elmer Corporation, The Uncharged polymers for separation of biomolecules by capillary electrophoresis
DE4425408A1 (en) * 1994-07-13 1996-01-18 Hoechst Ag cycloolefin
US5571410A (en) * 1994-10-19 1996-11-05 Hewlett Packard Company Fully integrated miniaturized planar liquid sample handling and analysis device
FR2738573B1 (en) 1995-09-08 1997-10-17 Rhone Poulenc Chimie USE AS THERMO-THICKENING AGENTS OF MULTIBLOCK COPOLYMERS
US5807937A (en) * 1995-11-15 1998-09-15 Carnegie Mellon University Processes based on atom (or group) transfer radical polymerization and novel (co) polymers having useful structures and properties
US5883211A (en) 1996-01-19 1999-03-16 Aclara Biosciences, Inc. Thermoreversible hydrogels comprising linear copolymers and their use in electrophoresis
DE69729726T2 (en) * 1996-05-24 2005-07-07 Zeptosens Ag METHOD FOR SEPARATING ACTIVE MIXTURES WITH CAPILLARAFFINITY GEL ELECTROPHORESIS
US6001232A (en) * 1996-09-04 1999-12-14 The Research Foundation Of State University Of New York Separation medium for capillary electrophoresis
US5989399A (en) 1996-09-04 1999-11-23 The Research Foundation Of State University Of New York Effective surface treatment for a new separation medium in electrophoresis
JP2001501653A (en) 1996-09-24 2001-02-06 シエル・インターナシヨネイル・リサーチ・マーチヤツピイ・ベー・ウイ Dispersant viscosity index improver
US6166149A (en) 1996-12-27 2000-12-26 Nippon Shokubai Co., Ltd. Hydrophilic graft polymer, production process therefor, composition containing the polymer, and use thereof
FR2764892B1 (en) * 1997-06-23 2000-03-03 Rhodia Chimie Sa PROCESS FOR THE SYNTHESIS OF BLOCK POLYMERS
US6114077A (en) 1998-07-31 2000-09-05 Agfa-Gevaert, N.V. White toner composition
US6162877A (en) * 1998-12-04 2000-12-19 Hercules Incorporated Hydrophobically modified comb copolymers
FR2788008B1 (en) 1998-12-30 2001-03-23 Inst Curie THERMOSENSITIVE MEDIUM FOR THE ELECTROKINETIC SEPARATION OF SPECIES WITHIN A SEPARATION CHANNEL
CA2358480A1 (en) 1999-01-12 2000-07-20 Spectrumedix Corporation Copolymers for capillary gel electrophoresis
US6306273B1 (en) * 1999-04-13 2001-10-23 Aclara Biosciences, Inc. Methods and compositions for conducting processes in microfluidic devices
FR2811083B1 (en) * 2000-06-30 2002-11-22 Inst Curie NON-THERMOSENSITIVE LIQUID MEDIUM FOR THE ANALYSIS OF SPECIES WITHIN A CHANNEL
US8975328B2 (en) * 2000-06-30 2015-03-10 Institute Curie Non-thermosensitive medium for analyzing species in a channel and for minimizing adsorption and/or electroosomosic phenomena
FR2810905B1 (en) * 2000-06-30 2003-05-16 Inst Curie ADDITIVE FOR MINIMIZING ADSORPTION AND / OR ELECTROOSMOSIS PHENOMENES

Also Published As

Publication number Publication date
WO2002001218A2 (en) 2002-01-03
US20190204266A1 (en) 2019-07-04
DE60121767T2 (en) 2007-08-02
US9658189B2 (en) 2017-05-23
EP1295113B1 (en) 2006-07-26
JP5038536B2 (en) 2012-10-03
EP1295113A2 (en) 2003-03-26
JP2012098304A (en) 2012-05-24
US20160238557A1 (en) 2016-08-18
ATE334386T1 (en) 2006-08-15
WO2002001218A3 (en) 2002-04-11
FR2811083A1 (en) 2002-01-04
US20040084310A1 (en) 2004-05-06
ES2269427T3 (en) 2007-04-01
JP2004502172A (en) 2004-01-22
FR2811083B1 (en) 2002-11-22
US20180024095A1 (en) 2018-01-25
AU2001270725A1 (en) 2002-01-08
CA2414295C (en) 2015-05-26
CA2414295A1 (en) 2002-01-03

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