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DE60113851D1 - Bakteriophage mit breitem wirtspektrum - Google Patents

Bakteriophage mit breitem wirtspektrum

Info

Publication number
DE60113851D1
DE60113851D1 DE60113851T DE60113851T DE60113851D1 DE 60113851 D1 DE60113851 D1 DE 60113851D1 DE 60113851 T DE60113851 T DE 60113851T DE 60113851 T DE60113851 T DE 60113851T DE 60113851 D1 DE60113851 D1 DE 60113851D1
Authority
DE
Germany
Prior art keywords
bakteriophage
hostel
wide
prophylaxis
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60113851T
Other languages
English (en)
Other versions
DE60113851T2 (de
Inventor
R Merril
Sankar Adhya
Deal Scholl
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
US Department of Health and Human Services
Original Assignee
US Department of Health and Human Services
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by US Department of Health and Human Services filed Critical US Department of Health and Human Services
Application granted granted Critical
Publication of DE60113851D1 publication Critical patent/DE60113851D1/de
Publication of DE60113851T2 publication Critical patent/DE60113851T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/76Viruses; Subviral particles; Bacteriophages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00Bacteriophages
    • C12N2795/00011Details
    • C12N2795/14011Details ssDNA Bacteriophages
    • C12N2795/14211Microviridae
    • C12N2795/14232Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/948Microorganisms using viruses or cell lines

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Virology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Toys (AREA)
  • Feedback Control In General (AREA)
DE60113851T 2000-07-25 2001-07-25 Bakteriophage mit breitem wirtsspektrum Expired - Lifetime DE60113851T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US22098700P 2000-07-25 2000-07-25
US220987P 2000-07-25
PCT/US2001/023390 WO2002007742A2 (en) 2000-07-25 2001-07-25 Bacteriophage having multiple host range

Publications (2)

Publication Number Publication Date
DE60113851D1 true DE60113851D1 (de) 2006-02-16
DE60113851T2 DE60113851T2 (de) 2006-07-20

Family

ID=22825862

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60113851T Expired - Lifetime DE60113851T2 (de) 2000-07-25 2001-07-25 Bakteriophage mit breitem wirtsspektrum

Country Status (8)

Country Link
US (1) US7163818B2 (de)
EP (1) EP1305038B1 (de)
AT (1) ATE305793T1 (de)
AU (1) AU2001278003A1 (de)
CA (1) CA2417188A1 (de)
DE (1) DE60113851T2 (de)
ES (1) ES2252263T3 (de)
WO (1) WO2002007742A2 (de)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000508322A (ja) * 1996-04-15 2000-07-04 エヌワイエムオーエックス コーポレーション バクテリオファージを含有する組成物および感染症を治療するためのバクテリオファージの使用方法
DE60231168D1 (de) 2001-06-15 2009-04-02 Prysmian Cables & Systems Ltd Verbinden optischer Fasern
EA007472B1 (ru) * 2001-07-18 2006-10-27 Институт Иммунологии И Терапии Досвядчальней Пан Поливалентные штаммы бактериофага, способы их получения и использования и содержащее указанные штаммы лекарственное средство
GB0209680D0 (en) 2002-04-27 2002-06-05 Univ Strathclyde Immobilisation and stabilisation of bacteriophage
US7588929B2 (en) 2002-12-09 2009-09-15 Phage Biopharm Llc Production of bacteriophage compositions for use in phage therapy
GB0300597D0 (en) 2003-01-10 2003-02-12 Microbiological Res Authority Phage biofilms
US7951579B2 (en) * 2003-04-07 2011-05-31 Board of Trutees of the University of Arkansas Method for bacteriophage delivery and amplification
EP2570130B1 (de) 2003-07-23 2014-11-26 Biocontrol Limited Bakteriophagen gegen P. aeruginosa enhaltende therapeutische Wirkstoffe
GB0320838D0 (en) 2003-09-05 2003-10-08 Univ Nottingham Disinfection of foodstuffs
US20090191254A1 (en) * 2004-12-06 2009-07-30 The Govt. Of The U.S.A., Centers For Disease Control And Prevention Inhibition of biofilm formation using bacteriophage
WO2006066224A2 (en) * 2004-12-14 2006-06-22 Yale University Virulence targeted antibiotics
CA2775655C (en) * 2005-01-20 2014-03-25 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Centers For Disease Control And Prevention Multiplexed analysis for determining a serodiagnosis of viral infection
EP1855723B1 (de) * 2005-03-08 2013-05-22 Ramot at Tel-Aviv University Ltd. Zielgerichtete arzneistofftragende bakteriophagen
WO2007007055A1 (en) * 2005-07-12 2007-01-18 The University Of Leeds Bacteriophage and their uses
WO2007044428A2 (en) * 2005-10-05 2007-04-19 Internalle, Inc. Method for liberating bacteriophages and uses thereof
JP5292278B2 (ja) 2006-04-04 2013-09-18 サントル ナショナル ドゥ ラ ルシェルシュ スィヤンティフィック(セーエヌエルエス) バクテリオファージ組成物の製造方法およびファージ治療分野における方法
KR100781669B1 (ko) * 2006-06-20 2007-12-03 주식회사 인트론바이오테크놀로지 황색포도상구균 특이적 사멸능을 갖는 박테리오파지
KR100759988B1 (ko) * 2006-08-04 2007-09-19 주식회사 인트론바이오테크놀로지 황색포도상구균에 특이적인 항균 단백질
FR2910492B1 (fr) * 2006-12-20 2013-02-15 Bio Modeling Systems Ou Bmsystems Procede de preparation de bacteriophages modifies par insertion de sequences aleatoires dans les proteines de ciblage desdits bacteriophages
FR2910493B1 (fr) * 2006-12-20 2012-12-14 Bio Modeling Systems Ou Bmsystems Procede de diversification aleatoire d'une sequence genetique permettant de preserver l'identite de certains segments internes de ladite sequence genetique
GB0704553D0 (en) 2007-03-09 2007-04-18 Harper David R Beneficial effects of bacteriophage treatments
CA2682444A1 (en) * 2007-03-30 2008-10-09 National Research Council Of Canada Phage receptor binding proteins for antibacterial therapy and other novel uses
KR100910961B1 (ko) * 2007-09-13 2009-08-05 주식회사 인트론바이오테크놀로지 황색포도상구균의 균막 처치에 효과적인 박테리오파지 또는그것 유래의 용균단백질
US20100092431A1 (en) * 2008-05-15 2010-04-15 Auburn University Edwardsiella Ictaluri Bacteriophage and Uses Thereof
US8377866B2 (en) * 2009-02-12 2013-02-19 Intron Biotechnology, Inc. Antimicrobial protein derived from Podoviridae bacteriophage specific to Staphylococcus aureus
TWI458734B (zh) * 2011-04-20 2014-11-01 Univ Nat Taiwan 對克雷伯氏肺炎桿菌(klebsiella pneumoniae)莢膜型菌株具專一性的新穎多肽及噬菌體及其應用
WO2013010660A1 (en) * 2011-07-15 2013-01-24 Medizinische Hochschule Hannover (Mhh) Enzymes having alpha2,9 endosialidase activity
RU2518303C2 (ru) * 2012-06-29 2014-06-10 Федеральное бюджетное учреждение науки "Московский научно-исследовательский институт эпидемиологии и микробиологии имени Г.Н. Габричевского" Федеральной службы по надзору в сфере защиты прав потребителей и благополучия человека (ФБУН МНИИЭМ им. Г.Н. Габричевского Роспотребнадзора) КОМПОЗИЦИЯ АНТИБАКТЕРИАЛЬНАЯ, ШТАММ БАКТЕРИОФАГА Escherichia coli, ИСПОЛЬЗУЕМЫЙ ДЛЯ ПОЛУЧЕНИЯ ТАКОЙ КОМПОЗИЦИИ.
WO2015035168A1 (en) * 2013-09-05 2015-03-12 Massachusetts Institute Of Technolgy Tuning bacteriophage host range
EP2893933A1 (de) 2014-01-10 2015-07-15 Pherecydes Pharma Phagentherapie von E.coli-Infektionen
GB201417810D0 (en) 2014-10-08 2014-11-19 Phico Therapeutics Ltd Modifying bacteriophage
GB201417805D0 (en) * 2014-10-08 2014-11-19 Phico Therapeutics Ltd Modifield bacteriophage
GB201417808D0 (en) * 2014-10-08 2014-11-19 Phico Therapeutics Ltd Modified bacteriophage
GB201417811D0 (en) * 2014-10-08 2014-11-19 Phico Therapeutics Ltd Modifying bacteriophage
EP3018201A1 (de) 2014-11-07 2016-05-11 Pherecydes Pharma Phagentherapie
EP3234136B1 (de) * 2014-12-16 2024-08-21 C3J Therapeutics, Inc. Zusammensetzungen von und verfahren für virales in vitro genomengineering
EP3901255A1 (de) 2016-04-08 2021-10-27 Phico Therapeutics Ltd Modifizierter bakteriophage
US10781441B2 (en) 2016-04-08 2020-09-22 Phico Therapeutics Ltd Modifying bacteriophage
EP3532850A1 (de) * 2016-10-28 2019-09-04 Massachusetts Institute Of Technology Synthetische bakteriophagen und bakteriophagenzusammensetzungen
KR101822812B1 (ko) * 2017-02-22 2018-01-29 주식회사 인트론바이오테크놀로지 신규한 엔테로코쿠스 패슘 박테리오파지 Ent-FAP-4 및 이의 엔테로코쿠스 패슘 증식 억제 용도
US10174295B1 (en) 2017-08-01 2019-01-08 The Charles Stark Draper Laboratory, Inc. Composition of matter: engineering of Escherichia coli phage K1E
GB201712733D0 (en) 2017-08-08 2017-09-20 Snipr Tech Ltd Methods & cells
CN111788304B (zh) * 2018-01-19 2024-10-01 噬菌体技术公司 基因工程噬菌体
GB201901099D0 (en) 2019-01-27 2019-03-13 Snipr Biome Aps Methods, uses and compositions
CA3143745A1 (en) * 2019-07-18 2021-01-21 Kilian VOGELE Host-independent expression of bacteriophages
CN112695017B (zh) * 2019-10-23 2022-04-15 吉林大学 噬菌体vB_Yen_X1及在防治鼠疫杆菌感染中应用
US11584781B2 (en) 2019-12-30 2023-02-21 Eligo Bioscience Chimeric receptor binding proteins resistant to proteolytic degradation
CN111876400B (zh) * 2020-08-06 2022-05-24 昆明理工大学 一种常温裂解酶Sly和编码此酶的多核苷酸
CN112143747B (zh) * 2020-09-09 2022-09-13 昆明理工大学 一种噬菌体裂解酶及其基因、基因重组表达载体与应用
CN113215114A (zh) * 2021-06-09 2021-08-06 西南石油大学 一种ndm-1大肠杆菌噬菌体及其分离方法和应用
ES3039826T3 (en) 2022-06-29 2025-10-24 Snipr Biome Aps Targeting e coli cells
GB202209518D0 (en) 2022-06-29 2022-08-10 Snipr Biome Aps Treating & preventing E coli infections
EP4621049A1 (de) * 2024-03-19 2025-09-24 Invitris GmbH Multispezifische partikel

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4405720A (en) 1981-03-04 1983-09-20 The United States Of America As Represented By The Department Of Health And Human Services Silver stains for protein in gels
US4508820A (en) 1982-08-13 1985-04-02 The United States Of America As Represented By The Department Of Health And Human Services Method for simultaneously monitoring turnover rate in multiple proteins
US4555490A (en) 1984-06-08 1985-11-26 The United States Of America As Represented By The Department Of Health And Human Services Rapid visualization system for gel electrophoresis
US4703016A (en) 1986-05-05 1987-10-27 The United States Of America As Represented By The Department Of Health And Human Services Silver stain for rapid, quantitative detection of polypeptides and nucleic acids
US4940659A (en) 1987-02-20 1990-07-10 Monoclonetics International, Inc. Screening extra-cellular body fluids for superoxide dismutase (SOD-1) for determining fetal trisomy 21 down syndrome
US4892814A (en) 1987-06-22 1990-01-09 The United States Of America As Represented By The Department Of Health And Human Services Method for distinguishing Creutzfeldt-Jakob disease from other dementias
US5817797A (en) 1988-06-01 1998-10-06 The United States Of America As Represented By The Department Of Health And Human Services Sequencing DNA; a modification of the polymerase chain reaction
US5292665A (en) 1989-03-15 1994-03-08 The United States Of America As Represented By The Department Of Health And Human Services Catalyst for preparing polyacrylamide gel which improves the detection of biomaterials by silver staining
US5844097A (en) 1990-11-30 1998-12-01 Monoclonetics International, Inc. Methods for the diagnosis of peripheral nerve damage
EP0559795B1 (de) 1990-11-30 1995-12-27 Monoclonetics International, Inc. Verfahren zur diagnose chronischer niedriger rückenschmerzen und nackenschmerzen
US5861504A (en) 1991-05-29 1999-01-19 The United States Of America As Represented By The Department Of Health And Human Services Eleven highly informative microsatelite repeat polymorphic DNA markers
US5468610A (en) 1991-05-29 1995-11-21 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Three highly informative microsatellite repeat polymorphic DNA markers
US5378602A (en) 1991-05-29 1995-01-03 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Highly informative microsatellite repeat polymorphic DNA markers twenty-[seven]six
US5429947A (en) 1992-06-17 1995-07-04 Merril; Carl R. Diagnosing Alzheimer's disease and schizophrenia
AU699322B2 (en) 1994-04-05 1998-12-03 Exponential Biotherapies, Inc. Antibacterial therapy with genotypically modified bacteriophage
US5811093A (en) 1994-04-05 1998-09-22 Exponential Biotherapies, Inc. Bacteriophage genotypically modified to delay inactivations by the host defense system
US20010043924A1 (en) 1994-04-05 2001-11-22 Exponential Biotherapies, Inc. Antibacterial therapy with bacteriophage physico-chemically altered to delay inactivation by the host defense system
US5736388A (en) * 1994-12-30 1998-04-07 Chada; Sunil Bacteriophage-mediated gene transfer systems capable of transfecting eukaryotic cells
SE506771C2 (sv) * 1996-02-06 1998-02-09 Gotpat 105 Ab Fusionsprotein, bakteriofag uttryckande proteinet, dessas användning samt hybridoma celler och monoklonaler producerade av cellerna
AU3737297A (en) * 1996-08-05 1998-02-25 Brigham And Women's Hospital Bacteriophage-mediated gene therapy
US20020177614A1 (en) 2001-03-23 2002-11-28 Merril Carl R. Methods for treating nuerodegenerative diseases including alzheimer's
US7521479B2 (en) 2001-04-16 2009-04-21 Panacea Pharmaceuticals, Inc. Methods of treating prion disease in mammals
EP1543169A4 (de) 2002-01-23 2007-09-12 Us Gov Health & Human Serv Verfahren zur bestimmung der empfindlichkeit gegenüber bakteriophagen
US7399753B2 (en) 2002-02-25 2008-07-15 Virxsys Corporation Trans-splicing mediated photodynamic therapy

Also Published As

Publication number Publication date
WO2002007742A9 (en) 2002-04-18
ES2252263T3 (es) 2006-05-16
WO2002007742A2 (en) 2002-01-31
US7163818B2 (en) 2007-01-16
DE60113851T2 (de) 2006-07-20
EP1305038A2 (de) 2003-05-02
ATE305793T1 (de) 2005-10-15
CA2417188A1 (en) 2002-01-31
AU2001278003A1 (en) 2002-02-05
EP1305038B1 (de) 2005-10-05
US20030216338A1 (en) 2003-11-20
WO2002007742A8 (en) 2003-10-30
WO2002007742A3 (en) 2002-08-08

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