[go: up one dir, main page]

DE60107416D1 - Adnf mischungen zur verbesserung der lernfähigkeit und der gedächtnisfunktion - Google Patents

Adnf mischungen zur verbesserung der lernfähigkeit und der gedächtnisfunktion

Info

Publication number
DE60107416D1
DE60107416D1 DE60107416T DE60107416T DE60107416D1 DE 60107416 D1 DE60107416 D1 DE 60107416D1 DE 60107416 T DE60107416 T DE 60107416T DE 60107416 T DE60107416 T DE 60107416T DE 60107416 D1 DE60107416 D1 DE 60107416D1
Authority
DE
Germany
Prior art keywords
adnf
blends
memory function
improve learning
learning
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60107416T
Other languages
English (en)
Other versions
DE60107416T2 (de
Inventor
Y Spong
Douglas Brenneman
Illana Gozes
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ramot at Tel Aviv University Ltd
US Department of Health and Human Services
Original Assignee
Ramot at Tel Aviv University Ltd
US Department of Health and Human Services
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ramot at Tel Aviv University Ltd, US Department of Health and Human Services filed Critical Ramot at Tel Aviv University Ltd
Publication of DE60107416D1 publication Critical patent/DE60107416D1/de
Application granted granted Critical
Publication of DE60107416T2 publication Critical patent/DE60107416T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Virology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Psychology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Addiction (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Communicable Diseases (AREA)
  • Emergency Medicine (AREA)
DE60107416T 2000-05-31 2001-05-31 Adnf mischungen zur verbesserung der lernfähigkeit und der gedächtnisfunktion Expired - Lifetime DE60107416T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US20894400P 2000-05-31 2000-05-31
US208944P 2000-05-31
US26780501P 2001-02-08 2001-02-08
US267805P 2001-02-08
PCT/US2001/017758 WO2001092333A2 (en) 2000-05-31 2001-05-31 Use of adnf for enhancing learning and memory

Publications (2)

Publication Number Publication Date
DE60107416D1 true DE60107416D1 (de) 2004-12-30
DE60107416T2 DE60107416T2 (de) 2005-12-01

Family

ID=26903662

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60107416T Expired - Lifetime DE60107416T2 (de) 2000-05-31 2001-05-31 Adnf mischungen zur verbesserung der lernfähigkeit und der gedächtnisfunktion

Country Status (11)

Country Link
US (2) US7427598B2 (de)
EP (1) EP1285000B1 (de)
JP (1) JP4440536B2 (de)
CN (1) CN1444600A (de)
AT (1) ATE283286T1 (de)
AU (2) AU7511101A (de)
CA (1) CA2410735A1 (de)
DE (1) DE60107416T2 (de)
MX (1) MXPA02011923A (de)
NZ (1) NZ522821A (de)
WO (1) WO2001092333A2 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6613740B1 (en) * 1997-02-07 2003-09-02 Ramot University Authority For Applied Research And Industrial Development Ltd. Activity dependent neurotrophic factor III (ADNF III)
US7384908B1 (en) 1999-08-18 2008-06-10 National Institute Of Health Orally active peptides that prevent cell damage and death
EP1285000B1 (de) * 2000-05-31 2004-11-24 THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES Adnf mischungen zur verbesserung der lernfähigkeit und der gedächtnisfunktion
AU2002335750A1 (en) * 2001-09-12 2003-03-24 Ramot At Tel-Aviv University Ltd. Neurotrophic components of the adnf i complex
WO2004069870A2 (en) * 2003-02-10 2004-08-19 To-Bbb Holding B.V. Differentially expressed nucleic acids in the blood-brain barrier under inflammatory conditions
US7960334B2 (en) * 2003-03-12 2011-06-14 Ramot At Tel-Aviv University Ltd. Use of ADNF III polypeptides for treating mental diseases and disorders, including schizophrenia
JP4878551B2 (ja) 2004-04-08 2012-02-15 貞和 相磯 運動ニューロン疾患治療薬
US7452867B2 (en) 2005-03-23 2008-11-18 Ramot At Tel-Aviv University, Ltd. Use of ADNF polypeptides for treating peripheral neurotoxicity
TWI303567B (en) * 2005-12-20 2008-12-01 Ind Tech Res Inst Oligopeptide, derivative thereof, and pharmaceutical composition comprising the same
US20070185035A1 (en) * 2005-12-23 2007-08-09 Nastech Pharmaceutical Company Inc. Enhanced mucosal administration of neuroprotective peptides
CA2638827A1 (en) 2006-02-24 2007-08-30 Illana Gozes Protection of the retina against laser injury by adnf peptides such as nap and sal
AU2008291652A1 (en) * 2007-08-24 2009-03-05 Allon Therapeutics Inc. Neuroprotection using NAP-like and SAL-like peptide mimetics
US8586548B2 (en) 2009-08-17 2013-11-19 Ramot At Tel-Aviv University, Ltd. NAP alpha-aminoisobutyric acid analog with neuroprotective activity
US9518994B2 (en) 2010-01-06 2016-12-13 Ramot At Tel Aviv University Method for diagnosing and monitoring schizophrenia and tauopathies
WO2012015910A2 (en) * 2010-07-28 2012-02-02 Allon Therapeutics Inc. Use of adnf polypeptides for treating neurodegenerative diseases
EP3377089B1 (de) * 2015-11-18 2020-04-08 Herantis Pharma Plc Zusammensetzungen mit cdnf zur verwendung bei der intranasalen behandlung von erkrankungen des zentralnervensystems

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4587046A (en) * 1982-05-18 1986-05-06 The Regents Of The University Of California Drug-carrier conjugates
US6174862B1 (en) 1991-04-22 2001-01-16 Ramot University Authority For Applied Research And Industrial Development, Ltd. Neurotrophic peptides of activity dependent neurotrophic factor
JP3285862B2 (ja) * 1991-04-22 2002-05-27 アメリカ合衆国 活性依存性神経栄養因子
US6310040B1 (en) * 1991-11-08 2001-10-30 Cephalon, Inc. Treating retinal neuronal disorders by the application of insulin-like growth factors and analogs
JPH07508025A (ja) * 1992-05-08 1995-09-07 トーマス・ジェファーソン・ユニバーシティ インスリン様増殖因子（ｉｇｆ−１）類似体
US6613740B1 (en) * 1997-02-07 2003-09-02 Ramot University Authority For Applied Research And Industrial Development Ltd. Activity dependent neurotrophic factor III (ADNF III)
US6933277B2 (en) * 1999-03-12 2005-08-23 The United States Of America As Represented By The Department Of Health And Human Services Prevention of fetal alcohol syndrome and neuronal cell death with ADNF polypeptides
DE60010478T2 (de) 1999-08-18 2005-06-09 The Government Of The United States Of America As Represented By The Secretary, Department Of Health And Human Services Oral wirksame peptide, die zellschädigung und zelltod verhindern
US7384908B1 (en) * 1999-08-18 2008-06-10 National Institute Of Health Orally active peptides that prevent cell damage and death
EP1285000B1 (de) * 2000-05-31 2004-11-24 THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES Adnf mischungen zur verbesserung der lernfähigkeit und der gedächtnisfunktion

Also Published As

Publication number Publication date
WO2001092333A3 (en) 2002-05-30
JP4440536B2 (ja) 2010-03-24
WO2001092333A2 (en) 2001-12-06
AU2001275111B2 (en) 2006-07-06
US7427598B2 (en) 2008-09-23
ATE283286T1 (de) 2004-12-15
JP2003535105A (ja) 2003-11-25
NZ522821A (en) 2004-08-27
EP1285000A2 (de) 2003-02-26
HK1054947A1 (en) 2003-12-19
EP1285000B1 (de) 2004-11-24
AU7511101A (en) 2001-12-11
DE60107416T2 (de) 2005-12-01
CA2410735A1 (en) 2001-12-06
US20090203615A1 (en) 2009-08-13
MXPA02011923A (es) 2004-09-06
US20040048801A1 (en) 2004-03-11
CN1444600A (zh) 2003-09-24

Similar Documents

Publication Publication Date Title
DE60107416D1 (de) Adnf mischungen zur verbesserung der lernfähigkeit und der gedächtnisfunktion
EP1266025A4 (de) Proteingerüste für antikörper-mimetika und andere bindungsproteine
DK1482042T3 (da) Aktive og inaktive CC-kemokinreceptorer og nukleinsyremolekyler der koder for receptoren
DE59903410D1 (de) Hybridprotein zur hemmung der mastzelldegranulation und dessen verwendung
DE69829293D1 (de) Verwendung eines mittels zur verminderung des risikos kardiovaskulärer erkrankungen
DE69942459D1 (de) Isolierte nukleinsäuremoleküle die t-zellen induzierbare faktoren kodieren (tif), kodierte proteine und ihre anwendung
WO2008079290A3 (en) Stable buffered formulations containing polypeptides
ES2192157T1 (es) Metodo y dispositivo para determinacion de posicion.
EP2141243A3 (de) Proteingerüste für Antikörpermimetika und andere Bindungsproteine
ATE465748T1 (de) Vernetzte, nicht von pilzen kommende lipase enthaltende zusammensetzung und methoden zu deren verwendung
HRP20080464T3 (en) Method for purifying fsh
ATE429241T1 (de) Verfahren zur regulierung der stickstoffmonoxid- erzeugung
DE602005016800D1 (de) Hif-prolylhydroxylase-aktivitätstest
ATE382060T1 (de) Moleküle und verfahren zur inhibierung der freisetzung von kim-1
ATE347611T1 (de) Automatischer apparat zum messen von wassertoxizität
DE60129137D1 (de) Modulierung durch il-tif/interleukin-21
AU2003304419A8 (en) Botulinum neurotoxin b receptors and use thereof
DE60013093D1 (de) Methoden und kits zum sequenzieren von polypeptiden
DK1540335T3 (da) Screeningsfremgangsmåder til kognitive forstækere
DK1587526T3 (da) MNTF-peptider og sammensætninger og anvendelsesmåder
ATE555126T1 (de) Relaxin-chimere polypeptide und deren herstellung und anwendung
MXPA02007787A (es) Moleculas trade y uso relacionado con las mismas.
ATE339683T1 (de) Verfahren zur detektion und konzentrationsbestimmung von schwefelfreien odoriermitteln in erd- oder brenngas
WO2003053855A3 (en) Rapid high-throughput screen for detecting biological species in ballast water
WO2006084189A3 (en) Method for determining thermal stability of collagen or collagen-like peptide

Legal Events

Date Code Title Description
8364 No opposition during term of opposition