DE60106057D1 - Verfahren zur herstellung von baccatin iii-derivativen - Google Patents

Verfahren zur herstellung von baccatin iii-derivativen

Info

Publication number: DE60106057D1
Authority: DE; Germany
Prior art keywords: baccatin iii; iii derivatives; producing; producing baccatin; preparation
Prior art date: 2000-08-10
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

DE60106057T

Other languages

English (en)

Other versions

DE60106057T2 (de

Inventor

Alessandro Pontiroli

Ezio Bombardelli

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Indena SpA

Original Assignee

Indena SpA

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-08-10

Filing date

2001-07-27

Publication date

2004-11-04

2001-07-27 Application filed by Indena SpA filed Critical Indena SpA

2004-11-04 Publication of DE60106057D1 publication Critical patent/DE60106057D1/de

2006-02-23 Application granted granted Critical

2006-02-23 Publication of DE60106057T2 publication Critical patent/DE60106057T2/de

2021-07-28 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/08—Bridged systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Epoxy Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Peptides Or Proteins (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

DE60106057T 2000-08-10 2001-07-27 Verfahren zur herstellung von baccatin iii-derivativen Expired - Lifetime DE60106057T2 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
IT2000MI001869A IT1318678B1 (it)	2000-08-10	2000-08-10	Procedimento per la preparazione di derivati della baccatina iii.
ITMI20001869		2000-08-10
PCT/EP2001/008730 WO2002012215A1 (en)	2000-08-10	2001-07-27	Process for the preparation of baccatin iii derivatives

Publications (2)

Publication Number	Publication Date
DE60106057D1 true DE60106057D1 (de)	2004-11-04
DE60106057T2 DE60106057T2 (de)	2006-02-23

Family

ID=11445705

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE60106057T Expired - Lifetime DE60106057T2 (de)	2000-08-10	2001-07-27	Verfahren zur herstellung von baccatin iii-derivativen

Country Status (22)

Country	Link
US (2)	US6828445B2 (de)
EP (1)	EP1307436B1 (de)
JP (1)	JP4907043B2 (de)
KR (1)	KR100853056B1 (de)
CN (3)	CN100349882C (de)
AT (1)	ATE277919T1 (de)
AU (2)	AU8204001A (de)
CA (1)	CA2418829C (de)
CZ (1)	CZ302810B6 (de)
DE (1)	DE60106057T2 (de)
DK (1)	DK1307436T3 (de)
ES (1)	ES2228929T3 (de)
HU (1)	HU229316B1 (de)
IL (2)	IL154330A0 (de)
IT (1)	IT1318678B1 (de)
NO (1)	NO328124B1 (de)
PL (1)	PL200868B1 (de)
PT (1)	PT1307436E (de)
RU (1)	RU2264394C2 (de)
SI (1)	SI1307436T1 (de)
SK (1)	SK286653B6 (de)
WO (1)	WO2002012215A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1320107B1 (it) *	2000-11-28	2003-11-18	Indena Spa	Procedimento per la preparazione di derivati tassanici.
ITMI20012185A1 (it) *	2001-10-19	2003-04-19	Indena Spa	Procedimento per la preparazione della 14beta-idrossi-baccatina iii-1,14-carbonato
ITMI20012186A1 (it) *	2001-10-19	2003-04-19	Indena Spa	Procedimento per la preparazione della 14-beta-idrossi-baccatina iii-1,14-carbonato
ITMI20021921A1 (it) *	2002-09-10	2004-03-11	Indena Spa	Funzionalizzazione della posizione 14 dei nuclei tassanici e sintesi di nuovi derivati antitumorali.
US7446126B2 (en) *	2004-10-08	2008-11-04	Indena S.P.A.	Semisynthesis process for the preparation of 10-deacetyl-N-debenzoyl-paclitaxel
ITMI20050614A1 (it) *	2005-04-12	2006-10-13	Indena Spa	Processo per la purificazione della 10-deacetilbaccatina iii dalla 10-deacetil-2-debenzoil-2-pentenoilbaccatina iii
US20080151139A1 (en) *	2006-12-22	2008-06-26	Itt Manufacturing Enterprises, Inc.	Addressable backlight for LCD panel
DK2080764T3 (da)	2008-01-18	2012-09-24	Indena Spa	Faste former af ortataxel

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5698712A (en) *	1992-03-06	1997-12-16	Indena S.P.A.	Baccatine III derivatives
IT1254517B (it) *	1992-03-06	1995-09-25	Indena Spa	14-beta idrossi-10-deacetil-baccatina iii, suoi derivati, loro prepazione ed impiego terapeutico
FR2696460B1 (fr) *	1992-10-05	1994-11-25	Rhone Poulenc Rorer Sa	Procédé de préparation de dérivés du taxane.
US5475011A (en) *	1993-03-26	1995-12-12	The Research Foundation Of State University Of New York	Anti-tumor compounds, pharmaceutical compositions, methods for preparation thereof and for treatment
FR2721024B1 (fr) *	1994-06-09	1996-07-12	Rhone Poulenc Rorer Sa	Nouveaux taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.
IT1275936B1 (it) *	1995-03-17	1997-10-24	Indena Spa	Derivati della 10-deacetilbaccatina iii e della 10-deacetil-14b- idrossibaccatina iii loro metodo di preparazione e formulazioni
FR2732341A1 (fr) *	1995-03-27	1996-10-04	Rhone Poulenc Rorer Sa	Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
IT1275435B (it) *	1995-05-19	1997-08-07	Indena Spa	Derivati della 10-desacetil-14beta-idrossibaccatina iii,loro metodo di preparazione e formulazioni che li contengono
AU2187799A (en) *	1998-01-26	1999-08-09	Hanmi Pharmaceutical Co., Ltd.	Novel taxaneterpine compounds
IT1308636B1 (it) *	1999-03-02	2002-01-09	Indena Spa	Procedimento per la preparazione di tassani da 10-desacetilbaccatinaiii.
ITMI991483A1 (it) *	1999-07-06	2001-01-06	Indena Spa	Derivati tassanici e procedimenti per la loro preparazione
IT1320107B1 (it) *	2000-11-28	2003-11-18	Indena Spa	Procedimento per la preparazione di derivati tassanici.

2000
- 2000-08-10 IT IT2000MI001869A patent/IT1318678B1/it active
2001
- 2001-07-27 HU HU0303832A patent/HU229316B1/hu unknown
- 2001-07-27 PL PL360087A patent/PL200868B1/pl unknown
- 2001-07-27 WO PCT/EP2001/008730 patent/WO2002012215A1/en not_active Ceased
- 2001-07-27 CZ CZ20030365A patent/CZ302810B6/cs not_active IP Right Cessation
- 2001-07-27 SK SK159-2003A patent/SK286653B6/sk not_active IP Right Cessation
- 2001-07-27 AU AU8204001A patent/AU8204001A/xx active Pending
- 2001-07-27 SI SI200130208T patent/SI1307436T1/xx unknown
- 2001-07-27 CN CNB2005100873136A patent/CN100349882C/zh not_active Expired - Lifetime
- 2001-07-27 IL IL15433001A patent/IL154330A0/xx active IP Right Grant
- 2001-07-27 PT PT01960578T patent/PT1307436E/pt unknown
- 2001-07-27 DE DE60106057T patent/DE60106057T2/de not_active Expired - Lifetime
- 2001-07-27 CN CNA2007101617507A patent/CN101130528A/zh active Pending
- 2001-07-27 JP JP2002518192A patent/JP4907043B2/ja not_active Expired - Lifetime
- 2001-07-27 AU AU2001282040A patent/AU2001282040B8/en not_active Expired
- 2001-07-27 EP EP01960578A patent/EP1307436B1/de not_active Expired - Lifetime
- 2001-07-27 CN CNB018138675A patent/CN1254470C/zh not_active Expired - Lifetime
- 2001-07-27 KR KR1020037001790A patent/KR100853056B1/ko not_active Expired - Lifetime
- 2001-07-27 US US10/343,991 patent/US6828445B2/en not_active Expired - Lifetime
- 2001-07-27 DK DK01960578T patent/DK1307436T3/da active
- 2001-07-27 RU RU2003103776/04A patent/RU2264394C2/ru active
- 2001-07-27 CA CA002418829A patent/CA2418829C/en not_active Expired - Lifetime
- 2001-07-27 AT AT01960578T patent/ATE277919T1/de active
- 2001-07-27 ES ES01960578T patent/ES2228929T3/es not_active Expired - Lifetime
2003
- 2003-02-06 IL IL154330A patent/IL154330A/en unknown
- 2003-02-07 NO NO20030609A patent/NO328124B1/no not_active IP Right Cessation
2004
- 2004-10-26 US US10/972,674 patent/US7078538B2/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
NO328124B1 (no)	2009-12-14
US20040014998A1 (en)	2004-01-22
AU2001282040B2 (en)	2005-09-15
ES2228929T3 (es)	2005-04-16
CN1446207A (zh)	2003-10-01
PT1307436E (pt)	2004-11-30
IL154330A0 (en)	2003-09-17
AU2001282040B8 (en)	2006-01-19
IT1318678B1 (it)	2003-08-27
DK1307436T3 (da)	2005-01-31
CA2418829A1 (en)	2002-02-14
EP1307436A1 (de)	2003-05-07
HU229316B1 (en)	2013-10-28
HUP0303832A3 (en)	2005-02-28
HK1088325A1 (zh)	2006-11-03
US7078538B2 (en)	2006-07-18
ATE277919T1 (de)	2004-10-15
WO2002012215A1 (en)	2002-02-14
SI1307436T1 (en)	2005-02-28
CN100349882C (zh)	2007-11-21
NO20030609D0 (no)	2003-02-07
ITMI20001869A1 (it)	2002-02-10
CN1254470C (zh)	2006-05-03
US6828445B2 (en)	2004-12-07
CA2418829C (en)	2009-12-29
CZ2003365A3 (cs)	2003-06-18
SK1592003A3 (en)	2003-07-01
JP4907043B2 (ja)	2012-03-28
JP2004505961A (ja)	2004-02-26
RU2264394C2 (ru)	2005-11-20
PL200868B1 (pl)	2009-02-27
IL154330A (en)	2006-12-31
HUP0303832A2 (hu)	2004-03-01
HK1055964A1 (en)	2004-01-30
SK286653B6 (sk)	2009-03-05
CN101130528A (zh)	2008-02-27
AU8204001A (en)	2002-02-18
CZ302810B6 (cs)	2011-11-23
NO20030609L (no)	2003-02-07
KR100853056B1 (ko)	2008-08-19
EP1307436B1 (de)	2004-09-29
ITMI20001869A0 (it)	2000-08-10
US20050113585A1 (en)	2005-05-26
PL360087A1 (en)	2004-09-06
KR20030020454A (ko)	2003-03-08
CN1736995A (zh)	2006-02-22
DE60106057T2 (de)	2006-02-23

Publication	Publication Date	Title
ATE338044T1 (de)	2006-09-15	Herstellung von 1h-imidazoc4,5-c)chinolin-4- aminen ber 1h-imidazoc4,5-c)chinolin-4- phthalimidzwischenprodukte
ATE277919T1 (de)	2004-10-15	Verfahren zur herstellung von baccatin iii- derivativen
ATE344273T1 (de)	2006-11-15	Verfahren zur herstellung von 21-hydroxy-6,19- oxidoprogesteron (21oh-6op)
DE60105314D1 (de)	2004-10-07	Verfahren zur herstellung von taxanderivaten
ATE350372T1 (de)	2007-01-15	Verfahren und oxazolidin zwischenprodukt zur herstellung von taxanen
ATE281434T1 (de)	2004-11-15	Verfahren zur herstellung von benzoperhydroisoindolen
ATE244706T1 (de)	2003-07-15	Enantiomere von mercaptolactonen und verfahren zu ihrer herstellung
ATE325794T1 (de)	2006-06-15	Verfahren zur herstellung und zwischenprodukte von pyridin-2-yl-amin
ATE234288T1 (de)	2003-03-15	Verfahren zur herstellung eines buthylthuio- isochinolinderivates und zwischenprodukte dafür
ATE466847T1 (de)	2010-05-15	Verfahren zur herstellung von 14-beta- hydroxybaccatin-iii-1,14-carbonat
ATE537160T1 (de)	2011-12-15	Verfahren zur herstellung von 14beta- hydroxybaccatin-iii-1,14-carbonat
DE60103560D1 (de)	2004-07-01	Prozess zur herstellung von paclitaxel
ATE272038T1 (de)	2004-08-15	Verfahren zur herstellung von 2-alkyl-3- chlorphenolen
ATE326545T1 (de)	2006-06-15	Verfahren zur herstellung von d- oder l-menthol
ATE235461T1 (de)	2003-04-15	Verfahren zur herstellung von 3-cyano-2,4- dihalogen-5-fluor-benzoesäuren
ATE496054T1 (de)	2011-02-15	Verfahren zur herstellung von 1,3-dioxolan- nucleosiden
ATE425143T1 (de)	2009-03-15	Verfahren zur herstellung von indolen
ATE325111T1 (de)	2006-06-15	Verfahren zur herstellung von 15-pentadecanolid
ATE298762T1 (de)	2005-07-15	Verfahren zur herstellung von desclarithromycin, sowie zwischenprodukte
ATE458723T1 (de)	2010-03-15	Verfahren zur herstellung von 4,6-dichlor-5- fluorpyrimidin
ATE250581T1 (de)	2003-10-15	Verfahren zur herstellung von 3-cyanopyridin aus 2-methyl-1,5-pentandiamin
ATE281428T1 (de)	2004-11-15	Verfahren zur herstellung von methoxyimino- essigsäureamiden
ATE474575T1 (de)	2010-08-15	Pyridinverbindungen, ihre verfahren zur herstellung und anwendung
ATE236135T1 (de)	2003-04-15	Verfahren zur herstellung von 4,6- dichlorpyrimidin
DE59907019D1 (de)	2003-10-23	Verfahren zur herstellung von 4,4-dimethyl-5 alpha-cholesta-8,14,24-trien-3 beta-ol und zwischenprodukte im verfahren (i)

Legal Events

Date	Code	Title	Description
2005-10-27	8364	No opposition during term of opposition
2006-10-26	8328	Change in the person/name/address of the agent	Representative=s name: PFENNING MEINIG & PARTNER GBR, 80339 MUENCHEN
2009-07-30	8328	Change in the person/name/address of the agent	Representative=s name: MAIWALD PATENTANWALTSGESELLSCHAFT MBH, 80335 MUENC