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DE60104810D1 - Zellfreies Verfahren zur Herstellung von posttranslational veränderten Proteinen - Google Patents

Zellfreies Verfahren zur Herstellung von posttranslational veränderten Proteinen

Info

Publication number
DE60104810D1
DE60104810D1 DE60104810T DE60104810T DE60104810D1 DE 60104810 D1 DE60104810 D1 DE 60104810D1 DE 60104810 T DE60104810 T DE 60104810T DE 60104810 T DE60104810 T DE 60104810T DE 60104810 D1 DE60104810 D1 DE 60104810D1
Authority
DE
Germany
Prior art keywords
post
cell
production
modified proteins
translationally modified
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60104810T
Other languages
English (en)
Other versions
DE60104810T2 (de
Inventor
Cha Yong Choi
Sang Hyeon Kang
Taek Jin Kang
Ji Hyoung Woo
Sang Kil Lee
Seung Woo Cho
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DreamBiogen Co Ltd
Original Assignee
DreamBiogen Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by DreamBiogen Co Ltd filed Critical DreamBiogen Co Ltd
Application granted granted Critical
Publication of DE60104810D1 publication Critical patent/DE60104810D1/de
Publication of DE60104810T2 publication Critical patent/DE60104810T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/005—Glycopeptides, glycoproteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/505—Erythropoietin [EPO]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE60104810T 2001-02-07 2001-02-22 Zellfreies Verfahren zur Herstellung von posttranslational veränderten Proteinen Expired - Fee Related DE60104810T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2001-0005949A KR100399337B1 (ko) 2001-02-07 2001-02-07 단백질의 무세포 번역후수식법
KR2001005949 2001-02-07

Publications (2)

Publication Number Publication Date
DE60104810D1 true DE60104810D1 (de) 2004-09-16
DE60104810T2 DE60104810T2 (de) 2005-09-15

Family

ID=19705454

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60104810T Expired - Fee Related DE60104810T2 (de) 2001-02-07 2001-02-22 Zellfreies Verfahren zur Herstellung von posttranslational veränderten Proteinen

Country Status (6)

Country Link
US (2) US6780607B2 (de)
EP (1) EP1231278B1 (de)
JP (1) JP2002238595A (de)
KR (1) KR100399337B1 (de)
DE (1) DE60104810T2 (de)
ES (1) ES2227097T3 (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2686899B1 (fr) 1992-01-31 1995-09-01 Rhone Poulenc Rorer Sa Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant.
WO2001077137A1 (en) 2000-04-12 2001-10-18 Human Genome Sciences, Inc. Albumin fusion proteins
KR100399337B1 (ko) * 2001-02-07 2003-09-26 드림바이오젠 주식회사 단백질의 무세포 번역후수식법
AU2002349296A1 (en) * 2001-11-30 2003-06-10 Novozymes A/S Method for generating a site-specific library of variants
EP2277889B1 (de) 2001-12-21 2014-07-09 Human Genome Sciences, Inc. Fusionsproteine von Albumin und Interferon beta
JP4441170B2 (ja) * 2002-11-28 2010-03-31 独立行政法人理化学研究所 Ｓ１２リボソームタンパク質に変異を有する大腸菌細胞抽出液及びそれを用いる無細胞系によるタンパク質の製造方法
EP1594530A4 (de) 2003-01-22 2006-10-11 Human Genome Sciences Inc Albuminfusionsproteine
EP1634947A4 (de) * 2003-06-10 2007-10-03 Shimadzu Corp Extrakt aus einer kultivierten säugerzelle, verfahren zu dessen präparation und verfahren zur zellfreien proteinsynthese unter verwendung des extrakts
JP4091901B2 (ja) * 2003-11-13 2008-05-28 株式会社島津製作所 無細胞系タンパク質合成におけるミクロソーム膜添加による翻訳後修飾方法
JP3965437B2 (ja) * 2003-11-14 2007-08-29 国立大学法人山口大学 無細胞系タンパク質合成におけるミクロソーム膜添加による翻訳後修飾方法
JPWO2005075660A1 (ja) * 2004-02-03 2007-10-11 東洋紡績株式会社 改良された無細胞タンパク質合成用組成物
FR2870259A1 (fr) * 2004-05-12 2005-11-18 Univ D Aix Marseille I Procede de preparation de composes osidiques et des kits pour sa mise en oeuvre
JP4868731B2 (ja) 2004-11-17 2012-02-01 独立行政法人理化学研究所 哺乳動物培養細胞由来の無細胞タンパク質合成システム
JP4590249B2 (ja) * 2004-11-17 2010-12-01 独立行政法人理化学研究所 糖タンパク質合成用の無細胞タンパク質合成システム
JP4787488B2 (ja) * 2004-11-19 2011-10-05 独立行政法人理化学研究所 直鎖状鋳型ｄｎａを用いた無細胞タンパク質合成方法及びそのための細胞抽出液
WO2006078821A2 (en) * 2005-01-21 2006-07-27 Invitrogen Corporation Products and processes for in vitro synthesis of biomolecules
EP2010556B1 (de) * 2006-04-11 2015-09-23 Sloan-Kettering Institute for Cancer Research Homogenes erythropoïetin sowie ein verfahren zur deren bereitung
US7610567B2 (en) * 2006-04-27 2009-10-27 Achronix Semiconductor Corporation Systems and methods for performing automated conversion of representations of synchronous circuit designs to and from representations of asynchronous circuit designs
EP2213747B1 (de) * 2007-11-05 2021-06-30 Riken Verfahren zur herstellung eines membranproteins
DE102008054716A1 (de) * 2008-12-16 2010-06-17 Evonik Degussa Gmbh Inprozesskontrolle in einem Verfahren zur Herstellung von EPO
WO2015085209A1 (en) 2013-12-06 2015-06-11 President And Fellows Of Harvard College Paper-based synthetic gene networks
WO2015106276A1 (en) * 2014-01-13 2015-07-16 Magdalena Leszcyniecka Method for optimizing post-translational modifications on recombinant proteins
US9908064B2 (en) 2015-02-06 2018-03-06 Leidos, Inc. Portable fluidic platform for rapid cell-free production of protein biologics
CA3032514C (en) 2015-07-31 2021-05-04 Takehiro SHINODA Method of producing membrane protein and utilization thereof
CA3104859A1 (en) 2018-07-03 2020-01-09 Leidos, Inc. Materials and methods for cell-free expression of vaccine epitope concatemers
CN111484998B (zh) * 2019-05-30 2023-04-21 康码（上海）生物科技有限公司 体外定量共表达多种蛋白的方法及其应用
WO2023152519A2 (en) * 2022-02-14 2023-08-17 Nuclera Ltd Protein expression reagents for post-translational modifications

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ210501A (en) * 1983-12-13 1991-08-27 Kirin Amgen Inc Erythropoietin produced by procaryotic or eucaryotic expression of an exogenous dna sequence
JP2904583B2 (ja) 1991-10-11 1999-06-14 プロメガ・コーポレーション 真核無細胞抽出物中での転写と翻訳の共役
US6103489A (en) * 1997-03-21 2000-08-15 University Of Hawaii Cell-free protein synthesis system with protein translocation and processing
CA2364921A1 (en) * 1999-02-22 2000-08-31 European Molecular Biology Laboratory Translation system
KR100399337B1 (ko) * 2001-02-07 2003-09-26 드림바이오젠 주식회사 단백질의 무세포 번역후수식법

Also Published As

Publication number Publication date
DE60104810T2 (de) 2005-09-15
EP1231278B1 (de) 2004-08-11
US6780607B2 (en) 2004-08-24
EP1231278A1 (de) 2002-08-14
US20050084926A1 (en) 2005-04-21
ES2227097T3 (es) 2005-04-01
JP2002238595A (ja) 2002-08-27
US20020106719A1 (en) 2002-08-08
KR20020065769A (ko) 2002-08-14
KR100399337B1 (ko) 2003-09-26

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee