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DE60102925D1 - Amino-thiolester-verbindungen, diese enthaltende pharmazeutische und kosmetische zusammensetzungen und ihre anwendungen - Google Patents

Amino-thiolester-verbindungen, diese enthaltende pharmazeutische und kosmetische zusammensetzungen und ihre anwendungen

Info

Publication number
DE60102925D1
DE60102925D1 DE60102925T DE60102925T DE60102925D1 DE 60102925 D1 DE60102925 D1 DE 60102925D1 DE 60102925 T DE60102925 T DE 60102925T DE 60102925 T DE60102925 T DE 60102925T DE 60102925 D1 DE60102925 D1 DE 60102925D1
Authority
DE
Germany
Prior art keywords
pharmaceutical
amino
applications
cosmetic compositions
thiolester
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60102925T
Other languages
English (en)
Other versions
DE60102925T2 (de
Inventor
Guy Fournet
Antony Quash
Jacques Gore
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Galderma Research and Development SNC
Original Assignee
Galderma Research and Development SNC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Galderma Research and Development SNC filed Critical Galderma Research and Development SNC
Publication of DE60102925D1 publication Critical patent/DE60102925D1/de
Application granted granted Critical
Publication of DE60102925T2 publication Critical patent/DE60102925T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/08—Antiseborrheics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/12—Keratolytics, e.g. wart or anti-corn preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C327/00—Thiocarboxylic acids
    • C07C327/20—Esters of monothiocarboxylic acids
    • C07C327/22—Esters of monothiocarboxylic acids having carbon atoms of esterified thiocarboxyl groups bound to hydrogen atoms or to acyclic carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Molecular Biology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Communicable Diseases (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE60102925T 2000-05-31 2001-05-31 Amino-thiolester-verbindungen, diese enthaltende pharmazeutische und kosmetische zusammensetzungen und ihre anwendungen Expired - Lifetime DE60102925T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0007029 2000-05-31
FR0007029A FR2809727B1 (fr) 2000-05-31 2000-05-31 Nouveaux composes aminothiolesters, compositions pharmaceutiques et cosmetiques les contenant et utilisations
PCT/FR2001/001694 WO2001092220A1 (fr) 2000-05-31 2001-05-31 Composes aminothiolesters, compositions pharmaceutiques et cosmetiques les contenant et utilisations

Publications (2)

Publication Number Publication Date
DE60102925D1 true DE60102925D1 (de) 2004-05-27
DE60102925T2 DE60102925T2 (de) 2005-04-07

Family

ID=8850863

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60102925T Expired - Lifetime DE60102925T2 (de) 2000-05-31 2001-05-31 Amino-thiolester-verbindungen, diese enthaltende pharmazeutische und kosmetische zusammensetzungen und ihre anwendungen

Country Status (10)

Country Link
US (1) US8026231B2 (de)
EP (1) EP1296946B1 (de)
JP (1) JP4855626B2 (de)
AR (1) AR028122A1 (de)
AT (1) ATE264839T1 (de)
AU (1) AU2001274171A1 (de)
DE (1) DE60102925T2 (de)
ES (1) ES2219530T3 (de)
FR (1) FR2809727B1 (de)
WO (1) WO2001092220A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2983492B1 (fr) * 2011-12-06 2015-10-30 Advanced Biodesign Procede ex vivo de purge tumorale d'un echantillon biologique
AR106352A1 (es) * 2015-10-15 2018-01-03 Advanced Biodesign Compuestos de aminotioléster o las sales farmacéuticamente aceptables del mismo, para usar en el tratamiento del cáncer
JP7062592B2 (ja) * 2015-10-15 2022-05-06 アドヴァンスト・バイオデザイン アミノチオールエステル化合物またはその薬学的に許容される塩および対象の癌細胞におけるｈ２ｏ２濃度を増大し得る化合物の組み合わせ
FR3047734B1 (fr) * 2016-02-17 2019-09-06 Advanced Biodesign Procede de preparation de composes aminothiolester et leurs sels
JP7681566B2 (ja) * 2019-07-31 2025-05-22 アドヴァンスト・バイオデザイン アミノチオールエステル化合物及びその使用
FR3119314B1 (fr) 2021-01-29 2025-01-10 Advanced Biodesign Nanocapsule lipidique comprenant au moins un composé aminothiolester ou un de ses dérivés pharmaceutiquement acceptable
EP4035666A1 (de) 2021-01-29 2022-08-03 Advanced Biodesign Aminothiolesterverbindung oder derivate davon zur verwendung als immunmodulatorisches mittel
WO2025229179A1 (en) 2024-05-03 2025-11-06 Advanced Biodesign Use of aminothiolester compounds in combination with hypomethylating agents (hma) for the prevention and treatment of cancer

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5051528A (en) * 1990-04-24 1991-09-24 Eastman Kodak Company Recovery process for ethylene glycol and dimethylterephthalate
JPH0797350A (ja) * 1993-08-02 1995-04-11 Mitsubishi Chem Corp ベンゾイルアセチレン誘導体
FR2761606B1 (fr) * 1997-04-08 1999-05-14 Cird Galderma Utilisation de derives aminothiolesters dans le domaine pharmaceutique
CA2279892C (en) 1997-12-02 2008-02-12 Heinrich Smuda Method of recovery of terephthalic acid and ethylene glycol from poly/ethylene terephthalate/wastes
FR2777001B1 (fr) * 1998-04-01 2000-06-09 Cird Galderma Derives de l'acide 6,8-dimercaptooctanoique substitues en 6-s et/ou en 8-s par le radical (3-methylthiopropanoyl) et compositions pharmaceutiques destinees au traitement des tumeurs cancereuses
JP4067306B2 (ja) 1999-10-22 2008-03-26 帝人ファイバー株式会社 ポリエステル廃棄物からテレフタル酸ジメチル及びエチレングリコールを分離回収する方法
JP3808672B2 (ja) * 1999-11-26 2006-08-16 東洋製罐株式会社 回収ポリエチレンテレフタレート粉砕品からのテレフタル酸の工業的回収方法

Also Published As

Publication number Publication date
WO2001092220A1 (fr) 2001-12-06
ES2219530T3 (es) 2004-12-01
JP2003535076A (ja) 2003-11-25
JP4855626B2 (ja) 2012-01-18
US20070032476A1 (en) 2007-02-08
FR2809727A1 (fr) 2001-12-07
AU2001274171A1 (en) 2001-12-11
FR2809727B1 (fr) 2002-07-26
EP1296946A1 (de) 2003-04-02
ATE264839T1 (de) 2004-05-15
EP1296946B1 (de) 2004-04-21
AR028122A1 (es) 2003-04-23
DE60102925T2 (de) 2005-04-07
US8026231B2 (en) 2011-09-27

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